Actions of Tritus in details
Description: Tritus is an indirect acting sympathomimetic, often used orally as the HCl salt for nasal congestion. It has been withdrawn in several countries due to increased risk of haemorrhagic strokes.
Pharmacokinetics:
Absorption: Readily and completely absorbed from GI tract. Time to peak plasma concentration: 1-2 hr.
Metabolism: Undergoes partial hepatic metabolism.
Excretion: Via urine 80-90% (unchanged). Half-life: Approx 3-5 hr.
How should I take Tritus?
Take Tritus exactly as directed by your doctor, or follow the instructions that accompany the package. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass of water.
Never take this medication in larger doses or more often than is recommended. Too much Tritus could be very harmful.
If your symptoms are accompanied by a high fever, or if they do not improve in 7 days, see your doctor.
Store Tritus at room temperature away from moisture and heat.
Tritus pharmacology
Tritus (PPA), a sympathomimetic agent structurally similar to pseudoephedrine, is used to treat nasal congestion. Tritus is found in appetite suppressant formulations and with guaifenesinin in cough-cold formulations. In 2000, the FDA requested that all drug companies discontinue marketing products containing Tritus, due to an increased risk of hemorrhagic stroke in women who used Tritus.
References
- DailyMed. "CHLORPHENIRAMINE POLISTIREX; HYDROCODONE POLISTIREX: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "DEXTROMETHORPHAN HYDROBROMIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- NCIt. "Dextromethorphan: NCI Thesaurus (NCIt) provides reference terminology for many systems. It covers vocabulary for clinical care, translational and basic research, and public information and administrative activities.". https://ncit.nci.nih.gov/ncitbrowser... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Tritus are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Tritus. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
