Pregnancy of Varcold SUSP in details
In a review of deliveries to Michigan Medicaid patients during 1980 to 1983, 1489 exposures to Varcold SUSP any time during pregnancy were recorded. A total of 128 birth defects were reported (91 expected). An association was seen between Varcold SUSP and laryngotracheal anomalies, pyloric stenosis, intestinal fixation anomalies, upper limb defects, skull/face anomalies, and musculoskeletal defects. The statistical significance of these associations is not known. (written communication, Franz Rosa, MD, Food and Drug Administration, 1994). The Collaborative Perinatal Project monitored 50,282 mother-child pairs and recorded 726 first-trimester exposures and 2489 exposures to Varcold SUSP anytime during pregnancy. Possible associations between Varcold SUSP and first trimester use and Varcold SUSP include hypospadias (4), eye and ear abnormalities (7, statistically significant), polydactyly (6), cataract (3), and pectus excavatum (7). For use anytime during pregnancy a possible association was noted between Varcold SUSP use and congenital dislocation of hip (12).
Varcold SUSP has been assigned to pregnancy category C. There are no controlled data in human pregnancy. Varcold SUSP should only be used during pregnancy when benefit outweighs the risk to the fetus.
See references
Varcold SUSP breastfeeding
There are no data on the excretion of Varcold SUSP into human milk.
See references
References for pregnancy information
- Heinonen O, Slone D, Shapiro S; Kaufman DW ed. "Birth Defects and Drugs in Pregnancy." Littleton, MA: Publishing Sciences Group, Inc. (1977): 297
References for breastfeeding information
- "Product Information. Dexatrim (Varcold SUSP)." Thompson Medical Company Inc, West Palm Beach, FL.
- "Product Information. Propagest (Varcold SUSP)." Carnrick Laboratories Inc, Cedar Knolls, NJ.
- "Product Information. Rhindecon (Varcold SUSP)." McGregor Pharmaceuticals Inc, Largo, FL.
Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill, knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.
Reviews
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
