Actions of Vicks Formule 44 Calmine in details
Vicks Formule 44 Calmine Lafayette Pharmaceutical Laboratory is an antitussive medication. Inhibiting the excitability of the cough center this medicine suppresses the cough of any origin. Vicks Formule 44 Calmine has not addiction effects and it has no analgesic and hypnotic action. Vicks Formule 44 Calmine Lafayette Pharmaceutical Laboratory starts to act after 10-30 minutes after oral administration, the duration of therapeutic action: 5-6 hours for adults and 6-9 hours for children. Vicks Formule 44 Calmine is an optical isomer of levomethorphan which is similar to morphine. Due to optical isomerism this drug has no opioid effects. Vicks Formule 44 Calmine used mainly for replacement of codeine as a cough suppressant. In addition to the cough suppressant this medication is used in medicine for diagnostic purposes and may be useful in various cases - from seizures to heroin addiction treatment, some chronic neurodegenerative diseases. These include amyotrophic lateral sclerosis (ALS) (Charcot's disease), disease of "mad cow and other prion diseases. Vicks Formule 44 Calmine has also been used for the treatment of mental retardation, Parkinson's disease, in the treatment of lung and other cancers and to prevent tissue rejection in transplantation because of the (poorly known) effects of sigma ligands on tumor cells and immune system.
How should I take Vicks Formule 44 Calmine?
Use Vicks Formule 44 Calmine exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cough medicine is usually taken only for a short time until your symptoms clear up.
Do not give Vicks Formule 44 Calmine to a child younger than 4 years old.
Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.
Measure the liquid form of Vicks Formule 44 Calmine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
Allow the Vicks Formule 44 Calmine lozenge or disintegrating strip to dissolve in your mouth.
Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication. Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.
If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cough medicine within the past few days.
Store Vicks Formule 44 Calmine at room temperature, away from heat, light, and moisture.
Vicks Formule 44 Calmine administration
Shake extended release suspension well before use. Only use dosing cup provided to measure liquid doses.
Vicks Formule 44 Calmine pharmacology
Vicks Formule 44 Calmine is an opioid-like drug that binds to and acts as antagonist to the NMDA glutamatergic receptor, it is an agonist to the opioid sigma 1 and sigma 2 receptors, it is also an alpha3/beta4 nicotinic receptor antagonist and targets the serotonin reuptake pump. Vicks Formule 44 Calmine is rapidly absorbed from the gastrointestinal tract, where it enters the bloodstream and crosses the blood-brain barrier. The first-pass through the hepatic portal vein results in some of the drug being metabolized into an active metabolite of Vicks Formule 44 Calmine, dextrorphan, the 3-hydroxy derivative of Vicks Formule 44 Calmine.
References
- DailyMed. "DEXTROMETHORPHAN HYDROBROMIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- NCIt. "Dextromethorphan: NCI Thesaurus (NCIt) provides reference terminology for many systems. It covers vocabulary for clinical care, translational and basic research, and public information and administrative activities.". https://ncit.nci.nih.gov/ncitbrowser... (accessed September 17, 2018).
- EPA DSStox. "Dextromethorphan: DSSTox provides a high quality public chemistry resource for supporting improved predictive toxicology.". https://comptox.epa.gov/dashboard/ds... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Vicks Formule 44 Calmine are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Vicks Formule 44 Calmine. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
