Virlix-D Pregnancy

• Pregnancy of Virlix-D in details
• Virlix-D breastfeeding
• Virlix-D reviews

Pregnancy of Virlix-D in details

Cetirizine (Virlix-D)-Pseudoephedrine (Virlix-D) has been assigned to pregnancy category C by the FDA. High dose animal studies have revealed evidence of developmental toxicity. There are no controlled data in human pregnancy. Cetirizine (Virlix-D)-Pseudoephedrine (Virlix-D) is only recommended for use during pregnancy when there are no alternatives and benefit outweighs risk..

Virlix-D breastfeeding

Cetirizine (Virlix-D) is excreted into human milk. Cetirizine (Virlix-D) is considered contraindicated during breast-feeding by the manufacturer. Pseudoephedrine (Virlix-D) is excreted into human milk. Three mothers given Pseudoephedrine (Virlix-D) demonstrated milk concentrations consistently higher than plasma concentrations. Maximum milk concentrations were reached at 1 to 1.5 hours after dosing. In one woman, the milk:plasma concentration ratio at 1, 3, and 12 hours was 3.3, 3.9, and 2.6. The authors calculated that 1000 mL of breast milk consumed over 24 hours would provide an infant with 0.25 to 0.33 mg of Pseudoephedrine (Virlix-D), or 0.5% to 0.7% of the dose ingested by the mother. There are no reports of adverse effects in infants who were exposed to Pseudoephedrine (Virlix-D) in breast milk. Pseudoephedrine (Virlix-D) is considered compatible with breast-feeding by the American Academy of Pediatrics.

References

1. DailyMed. "PSEUDOEPHEDRINE SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
2. DailyMed. "CETIRIZINE HYDROCHLORIDE; PSEUDOEPHEDRINE HYDROCHLORIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
3. PubMed Health. "Pseudoephedrine (By mouth): This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology