Vitamin A Natural Source Overdose

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What happens if I overdose Vitamin A Natural Source?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Vitamin A Natural Source can cause serious or life-threatening side effects.

Overdose symptoms may include nausea, vomiting, loss of appetite, vision changes, hair loss, peeling skin, cracked skin around your mouth, changes in menstrual periods, dizziness, drowsiness, tired feeling, bone or joint pain, severe headache, pain behind your eyes, severe stomach pain, dark urine, or jaundice (yellowing of the skin or eyes).

Overdose of Vitamin A Natural Source in details

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The following amounts have been found to be toxic orally. Toxicity manifestations depend on the age, dosage, size, and duration of administration.

Acute toxicity — single dose (25,000 Units/kg body weight)

Infant: 350,000 Units

Adult: Over 2 million Units

Chronic toxicity (4,000 Units/kg body weight for 6 to 15 months)

Infants 3 to 6 months old: 18,500 Units (water dispersed)/day for 1 to 3 months.

Adult: 1 million Units daily for three days; 50,000 Units daily for longer than 18 months; 500,000 Units daily for two months.

Hypervitaminosis A Syndrome:

1.
General manifestations:

Fatigue, malaise, lethargy, abdominal discomfort, anorexia, and vomiting.

2.
Specific manifestations:
a. Skeletal: hepatotoxicity, hard tender cortical thickening over the radius and tibia, migratory arthralgia, slow growth, and premature closure of the epiphysis leading to arrested bone growth in children.

b. Central Nervous System: irritability, headache, and increased intracranial pressure as manifested by bulging fontanels, papilledema, and exophthalmos.

c. Dermatologic: fissures of the lips, drying and cracking of the skin, alopecia, scaling, massive desquamation, and increased pigmentation.

d. Systemic: hypomenorrhea, hepatosplenomegaly, hepatotoxicity, jaundice, leukopenia, Vitamin A Natural Source plasma level over 1,200 Units/100 mL.

The treatment of hypervitaminosis A consists of immediate withdrawal of the vitamin along with symptomatic and supportive treatment.

What should I avoid while taking Vitamin A Natural Source?

Avoid taking orlistat (alli, Xenical) or mineral oil while you are taking Vitamin A Natural Source.

Vitamin A Natural Source warnings

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Avoid overdosage. Keep out of the reach of children.

Pediatric Use: Polysorbates have been associated with E-Ferol syndrome (thrombocytopenia, renal dysfunction, hepatomegaly, cholestasis, ascites, hypotension and metabolic acidosis) in low birth-weight infants.

What should I discuss with my healthcare provider before taking Vitamin A Natural Source?

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

Vitamin A Natural Source precautions

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General: Protect from light. Prolonged daily dose administration over 25,000 Units Vitamin A Natural Source should be under close supervision. Blood level assays are not a direct measure of liver storage. Liver storage should be adequate before discontinuing therapy. Single Vitamin A Natural Source deficiency is rare. Multiple vitamin deficiency is expected in any dietary deficiency.

Drug Interactions: Women on oral contraceptives have shown a significant increase in plasma Vitamin A Natural Source levels.

Carcinogenesis: There are no studies that show that administration of Vitamin A Natural Source will cause or prevent cancer.

Pregnancy Category X:

Nursing Mothers: The U.S. Recommended Daily Allowance (RDA) of Vitamin A Natural Source (5,000 Units) is recommended for nursing mothers.

What happens if I miss a dose of Vitamin A Natural Source?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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