Vitamin B5 Uses

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Vitamin B5 indications

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Coenzyme A (metabolite of dexpanthenol) is important for deep penetrating moisturizer; stimulates epithelization; has wound healing effect; has an anti-inflammatory effect.

Only the D-Panthenol is the provitamin of D-Pantothenic acid (Vitamin B5), not the L-Panthenol.

A cream with dexpanthenol regularly applied to the skin improves the moisture content of dry skin significantly.

A cream with 5% dexpanthenol accelerates the healing of superficial wounds by approximately 30%.

An ointment with dexpanthenol prevents erythema due to UV light.

Dexpanthenol ointment also protects the lips against solar herpes, Sun burns, mild burns, skin irritations, dry or cracked skin, cosmetic or shaving rashes, post chemical peeling treatment, post laser resurfacing treatment ( 11th -15th day).

Dexpanthenol is effective for preventing / treating nappy dermatitis in infants.

Vitamin B5 interactions

Dextropanthenyl alcohol in combination with hydrocortisone may be more effective than topical hydrocortisone alone in some dermatoses.

Vitamin B5 side effects

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No serious side effects have been reported, even at intakes of up to 10,000 mg (10 grams) per day. Very large amounts of pantothenic acid (several grams per day) can cause diarrhea.

Pantothenic acid works together with vitamin B1, vitamin B2, and vitamin B3 to help make the fuel our bodies run on—ATP.

There is one report of a 76-year-old woman who developed a life-threatening condition (eosinophilic pleuropericardial effusion) while taking 300 mg of pantothenic acid per day and 10 mg of biotin per day.2 However, it is not clear whether the vitamins caused the problem.

Vitamin B5 contraindications

Haemophiliacs, patients with ileus (due to mechanical obstruction).

Active ingredient matches for Vitamin B5:

Vitamin B5


Unit description / dosage (Manufacturer)Price, USD
Tablet; Oral; D-Pantothenic Acid / Calcium D-Pantothenate 50 mg
Tablet; Oral; D-Pantothenic Acid / Calcium D-Pantothenate 250 mg

List of Vitamin B5 substitutes (brand and generic names):

Tablet; Oral; Vitamin B5 / Calcium D-Pantothenate 250 mg
Tablet; Oral; Vitamin B5 / Calcium D-Pantothenate 500 mg
Tablet; Oral; D-Pantothenic Acid / Calcium D-Pantothenate 100 mg
Capsule; Oral; Vitamin B5 / D-Pantothenic Acid 250 mg
Tablet, Extended Release; Oral; Vitamin B5 / D-Pantothenic Acid 1 g
Tablet; Oral; Vitamin B5 / D-Pantothenic Acid 500 mg
Tablet; Oral; D-Pantothenic Acid / Calcium D-Pantothenate 250 mg; Vitamin B1 5 mg; Vitamin B2 5 mg
Ointment; Topical; Vitamin B5 / Dexpanthenol 5%
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Spray; Nasal; Vitamin B5 / Dexpanthenol (Ratiopharm)
Tablet; Oral; Vitamin B5 / Calcium Pantothenate (Quimica medica)
Solution; Topical; Phenyl Mercuric Borate; Vitamin B5 / Panthenol 250 mg / ml (Pharmaselect)
Solution; Topical; Vitamin B5 / Panthenol 50 mg / ml (Pharmaselect)
Tablet; Oral; D-Pantothenic Acid / Calcium D-Pantothenate 100 mg
Tablet, Extended Release; Oral; Vitamin B5 / Calcium D-Pantothenate 1000 mg
Capsule; Oral; D-Pantothenic Acid 300 mg

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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