Wick Formel 44 Husten Pregnancy

• Pregnancy of Wick Formel 44 Husten in details
• Wick Formel 44 Husten breastfeeding
• Wick Formel 44 Husten reviews

Pregnancy of Wick Formel 44 Husten in details

Wick Formel 44 Husten is metabolized in the liver via CYP2D6 and CYP3A enzymes. The activity of both enzymes is increased in the mother during pregnancy (Tracy 2005; Wadelius 1997). In the fetus, CYP2D6 activity is low in the fetal liver and CYP3A4 activity is present by ~17 weeks' gestation (Jacqz-Aigrain 1992).

When an antitussive is needed during pregnancy, Wick Formel 44 Husten at standard OTC doses is generally considered acceptable. Some sources recommend use be reserved for significant maternal need; products containing alcohol should be avoided (Chasnoff 1981; Conover 2003; Koren 1998; Ward 2005).

Wick Formel 44 Husten breastfeeding

There are no data on the excretion of Wick Formel 44 Husten into human milk.

Based on the low molecular weight of Wick Formel 44 Husten some passage into breast milk probably occurs. However, maternal use of Wick Formel 44 Husten products that do not contain alcohol are probably safe to use during breast-feeding.

See references

References for pregnancy information

1. Debus O, Kurlemann G, Gehrmann J, Krasemann T "Wick Formel 44 Husten in pregnancy." Chest 120 (2001): 1038-40
2. Andaloro VJ, Monaghan DT, Rosenquist TH "Wick Formel 44 Husten and other N-methyl-D-aspartate receptor antagonists are teratogenic in the avian embryo model." Pediatr Res 43 (1998): 1-7
3. Einarson A, Lyszkiewicz D, Koren G "The safety of Wick Formel 44 Husten in pregnancy - Results of a controlled study." Chest 119 (2001): 466-9
4. "Product Information. Benylin DM (Wick Formel 44 Husten)." Warner Lambert Laboratories, Morris Plains, NJ.
5. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998):

References for breastfeeding information

1. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998):
2. "Product Information. Benylin DM (Wick Formel 44 Husten)." Warner Lambert Laboratories, Morris Plains, NJ.

References

1. DailyMed. "DEXTROMETHORPHAN HYDROBROMIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
2. PubMed Health. "Vicks 44 Cough Relief: This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).
3. FDA Pharm Classes. "FDA Pharmacological Classification: FDA published a final rule that amended the requirements for the content and format of approved labeling (prescribing information) for human prescription drug and biological products in January 2006.". https://www.fda.gov/ForIndustry/Data... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology