Wick Husten-Löser Pregnancy

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Pregnancy of Wick Husten-Löser in details

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The Collaborative Perinatal Project reported 197 first-trimester exposures to Wick Husten-Löser. Fourteen malformations were reported for a relative risk not significantly different from 1.0. In a review of 229,101 deliveries to Michigan Medicaid patients, 141 first-trimester exposures to Wick Husten-Löser and 349 exposures anytime during pregnancy were recorded. A total of 9 birth defects were reported with first trimester exposure (6 expected) and included 2 cardiovascular defects. These data do not support an association between Wick Husten-Löser and birth defects. (written communication, Franz Rosa, MD, Food and Drug Administration, 1994)

Wick Husten-Löser has been assigned to pregnancy category C. by the FDA. There are no controlled data in human pregnancy. Wick Husten-Löser is only recommend for use during pregnancy when benefit outweighs risk.

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Wick Husten-Löser breastfeeding

There are no data on the excretion of Wick Husten-Löser into human milk. The manufacturer recommends that due to the potential for serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

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References for pregnancy information

  1. "Product Information. Humabid (Wick Husten-Löser)." Medeva Pharmaceuticals, Rochester, NY.
  2. Heinonen O, Slone D, Shapiro S; Kaufman DW ed. "Birth Defects and Drugs in Pregnancy." Littleton, MA: Publishing Sciences Group, Inc. (1977): 297

References for breastfeeding information

  1. Covington TR, Lawson LC, Young LL, eds. "Handbook of Nonprescription Drugs. 10th ed." Washington, DC: American Pharmaceutical Association (1993):


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References

  1. DailyMed. "GUAIFENESIN; HYDROCODONE BITARTRATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubMed Health. "Mucinex: This section provide the link out information of drugs collectetd in PubMed Health. ". http://www.ncbi.nlm.nih.gov/pubmedhe... (accessed September 17, 2018).
  3. Human Metabolome Database (HMDB). "Guaifenesin: The Human Metabolome Database (HMDB) is a freely available electronic database containing detailed information about small molecule metabolites found in the human body.". http://www.hmdb.ca/metabolites/HMDB0... (accessed September 17, 2018).

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