• Zema Lotion indications
• Uses of Zema Lotion in details
• Zema Lotion description
• Zema Lotion dosage
• Zema Lotion interactions
• Zema Lotion side effects
• Zema Lotion contraindications

What is Zema Lotion?

Zema Lotion topical is used to treat many skin disorders, such as acne, dandruff, psoriasis, seborrheic dermatitis of the skin and scalp, calluses, corns, common warts, and plantar warts, depending on the dosage form and strength of the preparation.

Zema Lotion is available without a prescription. Some of these preparations are available only with your doctor's prescription.

Zema Lotion indications

For Dermatologic Use: Zema Lotion 6% is a topical aid in the removal of excessive keratin in hyperkeratotic skin disorders including verrucae, and the various ichthyoses (vulgaris, sex-linked and lamellar), keratosis palmaris and plantaris keratosis pilaris, pityriasis rubra pilaris, and psoriasis (including body, scalp, palms and soles).

For Podiatric Use: Zema Lotion 6% is a topical aid in the removal of excessive keratin on dorsal and plantar hyperkeratotic lesions.

Topical preparations of 6% Zema Lotion have been reported to be useful adjunctive therapy for verrucae plantares.

How should I use Zema Lotion?

Use Zema Lotion shampoo as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• To use shampoo as a scalp treatment: Use before bathing. Do not wet hair. Apply Zema Lotion shampoo with the applicator directly to affected areas of the scalp. Leave on for 5 minutes, gradually increasing the treatment time up to 1 hour, or as directed by your doctor. After treatment, rinse thoroughly with water. Wash your hands after each use. You may use a non-medicated shampoo after using Zema Lotion shampoo, if desired.
• To use shampoo as a medicated shampoo: Wet hair, apply Zema Lotion shampoo with the applicator directly to scalp, and massage vigorously for several minutes. Rinse thoroughly. Be sure to wash your hands after each use. Use Zema Lotion shampoo daily until the condition clears, or as directed by your doctor.
• To use the gel on the skin: Moisten the affected area and keep damp for at least 5 minutes before you apply Zema Lotion shampoo. Apply Zema Lotion shampoo to the affected area as directed. Cover the treated area at night unless your doctor tells you otherwise. If applying to an area that cannot be covered, check with your doctor for instructions. Wash Zema Lotion shampoo off in the morning.
• To use gel as a scalp treatment: Apply Zema Lotion shampoo with the applicator directly to affected areas of the scalp. Avoid contact with unaffected hair or skin. Leave the medicine on for 10 to 20 minutes initially, gradually increasing the treatment time to one hour, or as directed by your doctor. The gel may be washed off using the medicated shampoo or warm water in a bath or shower.
• Wash hands immediately after you use Zema Lotion shampoo, unless your hands are part of the treated area.
• If you miss a dose of Zema Lotion shampoo, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Zema Lotion shampoo.

Uses of Zema Lotion in details

This medication is used on the skin to treat common skin and foot (plantar) warts. Zema Lotion helps cause the wart to gradually peel off. This medication is also used to help remove corns and calluses. This product should not be used on the face or on moles, birthmarks, warts with hair growing from them, or genital/anal warts.

Zema Lotion is a keratolytic. It belongs to the same class of drugs as aspirin (salicylates). It works by increasing the amount of moisture in the skin and dissolving the substance that causes the skin cells to stick together. This makes it easier to shed the skin cells. Warts are caused by a virus. Zema Lotion does not affect the virus.

How to use Zema Lotion topical

Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

This medication is for use on the skin only. To avoid irritation, do not let this medication come into contact with your eyes, nose, mouth, groin, or any broken skin. If you do get the medication in those areas, flush the area with cool water for 15 minutes. Wash hands after use.

First, soak the corn, callus, or wart in warm water for about 5 minutes to soften the treatment area. Dry thoroughly. Your doctor may direct you to use a pumice stone, callus file, or emery board to carefully remove the top dead layers of skin after soaking and before applying the medication. This dead skin removal is only to help the medication work better. Do not try to rub the wart or callus off.

If you are using a liquid/gel, apply a few drops or a thin coat of the medication to cover the entire wart, callus, or corn using the applicator if provided. Be careful to apply it only to the affected area and not the surrounding skin. Let dry for 5 minutes. Depending on the brand used, you may need to apply the medication twice with each treatment. Check your product package and follow the directions carefully. You may cover the area loosely with a bandage. Repeat this procedure 1 to 2 times daily for up to 2 weeks for corns and calluses and 12 weeks for warts or as directed by your doctor.

If you are using a medicated pad or bandage, you may need to cut the pad so that it covers the treatment area completely but does not touch the surrounding skin. Peel off the protective covering and place the patch/bandage over the area. Leave in place according to package directions. Remove and place a new patch/bandage as directed (usually every 8 to 48 hours depending on brand). Repeat this procedure for up to 2 weeks for corns and calluses and 12 weeks for warts.

Dosage is based on your medical condition, product type/brand, and response to treatment. Do not use large amounts, apply this medication more often, or use it for a longer period than directed. Your condition will not clear faster, but the chance for side effects may be increased.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day.

If your condition persists or worsens, or if you think you may have a serious medical problem, seek immediate medical attention.

Zema Lotion description

Each mL contains anthraquinone glycosides 50 mg, Zema Lotion 10 mg and alcohol 60%.

Zema Lotion dosage

Zema Lotion Dosage

Generic name: Zema Lotion 275mg in 1mL

Dosage form: topical solution

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Rx only

FOR TOPICAL USE ONLY.

NOT FOR OPHTHALMIC, ORAL OR INTRAVAGINAL USE.

DESCRIPTION

Zema Lotion is a topical preparation containing 27.5% Zema Lotion in a proprietary film-forming vehicle that comprises isopropyl alcohol, butyl acetate, polyvinyl butyral, isopropyl metacresol, trimethyl pentanyl diisobutyrate, phenic acid and acrylates copolymer. The pharmacologic activity of Zema Lotion is generally attributed to the keratolytic activity of Zema Lotion which is incorporated into a polyacrylic, film-forming virucidal vehicle designed to cover the wart without the need for a bandage. The structural formula of Zema Lotion is:

CLINICAL PHARMACOLOGY

Although the exact mode of action for Zema Lotion in the treatment of warts is unknown, its activity appears to be associated with its keratolytic action, which results in mechanical removal of epidermal cells infected with wart viruses.

The virucidal complex incorporated into Zema Lotion’s proprietary vehicle is designed to help reduce risk of reinfection at the wart site, as well as prevent viral contamination of the product under normal usage.

INDICATIONS AND USAGE

Zema Lotion is indicated for the topical treatment and removal of common warts and plantar warts.

CONTRAINDICATIONS

Patients with diabetes or impaired blood circulation should not use Zema Lotion. Zema Lotion also should not be used on moles, birthmarks, and unusual warts with hair growing from them, or warts on the face.

PRECAUTIONS

Zema Lotion is for external use only. Do not permit Zema Lotion to contact eyes or mucous membranes. If contact with eyes or mucous membranes occurs, immediately flush with water for 15 minutes. Zema Lotion should not be allowed to contact normal skin surrounding wart, since localized irritation may occur. Treatment should be discontinued if excessive irritation occurs. Zema Lotion is flammable. Keep away from fire or flame. Keep bottle tightly capped when not in use.

ADVERSE REACTIONS

A localized irritant reaction may occur if Zema Lotion is applied to the normal skin surrounding the wart. Any irritation may normally be controlled by temporarily discontinuing use and by applying the medication only to the wart site when treatment is resumed.

DOSAGE AND ADMINISTRATION

Prior to applying Zema Lotion, soak wart in warm water for five minutes. Remove any loosened tissue by gently rubbing with a brush, wash cloth, or emery board. Dry wart site thoroughly. Using the brush applicator supplied, apply Zema Lotion twice to entire wart surface, allowing the first application to dry before applying the second. Continue treatment once or twice a day as directed by physician. Be careful not to apply to surrounding skin.

Clinically visible improvement will normally occur during the first or second week of therapy. Maximum resolution may be expected after four to six weeks of Zema Lotion use.

HOW SUPPLIED

Zema Lotion is supplied in 10ml amber bottles with a brush applicator (NDC 42783-312-10).

Store at controlled room temperature, 15° to 30°C (59° to 86°F).

Manufactured for:

Elorac, Inc.

Vernon Hills, IL 60061

U.S. Patent Pending

Revised 06/2011

221619

More about Zema Lotion (Zema Lotion topical)

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Zema Lotion interactions

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to Zema Lotion or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Young children may be at increased risk of unwanted effects because of increased absorption of Zema Lotion through the skin. Also, young children may be more likely to get skin irritation from Zema Lotion. Zema Lotion should not be applied to large areas of the body, used for long periods of time, or used under occlusive dressing (air-tight covering, such as kitchen plastic wrap) in infants and children. Zema Lotion should not be used in children younger than 2 years of age.

Geriatric

Elderly people are more likely to have age-related blood vessel disease. This may increase the chance of problems during treatment with Zema Lotion.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Zema Lotion side effects

See also:
What are the possible side effects of Zema Lotion?

Less common or rare

Skin irritation not present before use of Zema Lotion (moderate or severe)

Frequency not known

Dryness and peeling of skin

flushing

redness of skin

unusually warm skin

Symptoms of Zema Lotion poisoning

Confusion

diarrhea

dizziness

fast or deep breathing

headache (severe or continuing)

hearing loss

lightheadedness

nausea

rapid breathing

ringing or buzzing in ears (continuing)

severe drowsiness

stomach pain

vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

-Skin irritation not present before use of Zema Lotion (mild) -stinging

Zema Lotion contraindications

See also:
What is the most important information I should know about Zema Lotion?

Less common or rare

Skin irritation not present before use of Zema Lotion (moderate or severe)

Frequency not known

Dryness and peeling of skin

flushing

redness of skin

unusually warm skin

Symptoms of Zema Lotion poisoning

Confusion

diarrhea

dizziness

fast or deep breathing

headache (severe or continuing)

hearing loss

lightheadedness

nausea

rapid breathing

ringing or buzzing in ears (continuing)

severe drowsiness

stomach pain

vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

-Skin irritation not present before use of Zema Lotion (mild) -stinging

Active ingredient matches for Zema Lotion:

Salicylic acid in Thailand.

Phenol 0825%/resorcinol 38%/Salicylic acid 118% in Thailand.

References

1. PubChem. "salicylic acid". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
2. DrugBank. "salicylic acid". http://www.drugbank.ca/drugs/DB00936 (accessed September 17, 2018).
3. DTP/NCI. "salicylic acid: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology