What are the possible side effects of Guarana seed?
Although rare, serious side effects from Guarana seed have been reported. Stop taking Guarana seed and seek emergency medical attention if you experience
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a serious allergic reaction including difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives; or
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irregular heartbeats or chest pain.
Other less serious side effects may also reported with the use of Guarana seed. Talk to your doctor or health care provider if you experience
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heartburn;
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upset stomach;
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loss of appetite;
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constipation or diarrhea;
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nervousness, irritability, or anxiety;
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sleeplessness;
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irregular heartbeats; or
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headache.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Side effects of Guarana seed in details
Cardiovascular
Tachycardia; extrasystoles; palpitations; other cardiac arrhythmias.
CNS
Insomnia; restlessness; excitement; nervousness; tinnitus; scintillating scotoma; muscular tremor; headache; lightheadedness.
Dermatologic
Urticaria; rash, dry skin, skin breakdown (caffeine citrate).
EENT
Retinopathy of prematurity (caffeine citrate).
GI
Vomiting; nausea; diarrhea; stomach pain; necrotizing enterocolitis, gastritis, GI hemorrhage (caffeine citrate).
Genitourinary
Diuresis; kidney failure (caffeine citrate).
Hematologic
Disseminated intravascular coagulation (caffeine citrate).
Metabolic
Hyperglycemia; acidosis (caffeine citrate).
Respiratory
Dyspnea, lung edema (caffeine citrate).
Miscellaneous
Hypersensitivity (eg, dermatitis, rhinitis, bronchial asthma); feeding intolerance, sepsis, accidental injury, hemorrhage, cerebral hemorrhage (caffeine citrate).
What is the most important information I should know about Guarana seed?
Guarana seed, or its active constituent caffeine, should not be taken when formulated with ephedrine in diet aids or performance-enhancing supplements. Potentially fatal irregular heartbeats have been reported to occur.
Guarana seed has not been evaluated by the FDA for safety, effectiveness, or purity. All potential risks and/or advantages of Guarana seed may not be known. Additionally, there are no regulated manufacturing standards in place for these compounds. There have been instances where herbal/health supplements have been sold which were contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.
Guarana seed contraindications
Caffeine and sodium benzoate solution in pediatrics
Reviews
The results of a survey conducted on ndrugs.com for Guarana seed are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Guarana seed. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported side effects
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Information checked by Dr. Sachin Kumar, MD Pharmacology