Actions of Jodostin in details
Description:
Oral Jodostin (converted to iodide) is essential for synthesis of thyroid hormones.
Topical Jodostin acts as a local irritant and as a germicide active against gram-positive and gram-negative bacteria, fungi, trichomonas, cysts, viruses and some spores.
Pharmacokinetics:
Absorption: Slightly absorbed (topical); transported and concentrated in the thyroid gland (oral).
Distribution:
Oral: Crosses the placenta; enters breast milk.
Excretion:
Oral: Mainly via urine; via faeces, saliva and sweat (small amounts).
How should I take Jodostin?
Use Jodostin only as directed.
Jodostin is for external use only. Do not swallow it.
Keep Jodostin away from the eyes because it may cause irritation. If you should accidentally get some in your eyes, wash it away with water immediately.
Do not use topical Jodostin on deep, puncture wounds, animal bites, or serious burns. To do so may increase the chance of side effects.
Do not cover the wound to which you have applied topical Jodostin with a tight dressing or bandage since this may increase the chance of side effects.
Dosing
The dose of Jodostin will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of Jodostin. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For topical dosage form (tincture):
- For minor bacterial skin infections:
- Adults and children 1 month of age and over—Use when necessary, according to the directions on the label or your doctor's instructions. Do not use for more than ten days.
- Infants and children under 1 month of age—Use is not recommended.
- For minor bacterial skin infections:
To help clear up your infection completely, it is very important that you keep using topical Jodostin for the full time of treatment. Do not miss any doses.
Missed Dose
If you miss a dose of Jodostin, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
Storage
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Jodostin administration
Topical: Iodosorb®: Apply /" thickness to dry sterile gauze, then place prepared gauze onto clean wound. Change dressing when gel changes color from brown to yellow/gray (~3 times/week). Remove with sterile water, saline, or wound cleanser; gently blot fluid from surface leaving wound slightly moist before reapplying gel.
Jodostin pharmacology
Jodostin is required for thyroid hormone synthesis. Jodostin is also known to be a powerful broad spectrum germicidal agent effective against a wide range of bacteria, viruses, fungi, protozoa, and spores. Iodosorb® and Iodoflex™ contain Jodostin in hydrophilic beads of cadexomer which allows a slow release of Jodostin into the wound and absorption of fluid, bacteria, and other substances from the wound
Absorption
Topical: Amount absorbed systemically depends upon concentration and characteristics of skin
Distribution
Primarily trapped by the thyroid
Metabolism
Degraded by amylases normally present in wound fluid
Excretion
Urine (>90%)
References
- NCIt. "Iodine: NCI Thesaurus (NCIt) provides reference terminology for many systems. It covers vocabulary for clinical care, translational and basic research, and public information and administrative activities.". https://ncit.nci.nih.gov/ncitbrowser... (accessed September 17, 2018).
- EPA DSStox. "Iodine: DSSTox provides a high quality public chemistry resource for supporting improved predictive toxicology.". https://comptox.epa.gov/dashboard/ds... (accessed September 17, 2018).
- EPA Office of Pesticide Programs. "The EPA OPP Pesticide Ecotoxicity Database, updated by the Ecological Fate and Effects Division of the EPA Office of Pesticide Programs, contains all EPA reviewed ecotoxicity endpoints for pesticides registered or previously registered in the U.S. Toxicity data. ". http://www.ipmcenters.org/Ecotox/ind... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Jodostin are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Jodostin. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology