Maxima MD indications
Contraceptive used to prevent pregnancy.
Oral contraceptives are very effective method of birth control. The chance of becoming pregnant is very low when the pill is taken correctly.
Maxima MD may also have non-contraceptive health benefits: Prevent weight gain and other symptoms eg, bloating and swelling which are related to fluid retention.
Drospirenone (Maxima MD) also has antiandrogenic activity which can help to reduce acne and greasiness of the skin and hair. With these special properties, Drospirenone (Maxima MD) is similar to the natrual progesterone hormone produced by the body.
The risk of anemia may be lower since the period may be lighter and shorter. The menstrual pains may also become less severe and completely disappear.
Maxima MD description
Each pink active film-coated tablet contains Drospirenone (Maxima MD) 3 mg and Ethinylestradiol (Maxima MD) 20 mcg as active substances. The white film-coated tablets do not contain active substances. It also contains the following ingredients: Pink active film-coated tablets: Tablet Core: Lactose monohydrate, pregelatinized starch (maize), povidone, croscarmellose sodium, polysorbate 80, magnesium stearate. Coating: Partially hydrolyzed polyvinyl alcohol, titanium dioxide (E171), macrogol 3350, talc, yellow iron oxide (E172), red iron oxide (E172), black iron oxide (E172). White film-coated tablets: Tablet Core: Anhydrous lactose, povidone, magnesium stearate. Coating: Partially hydrolized polyvinyl alcohol, titanium dioxide (E171), macrogol 3350, talc.
Each blister contains 28 tablets, 24 pink, active film-coated tablets in the 1st, 2nd, 3rd and 4th rows of the strip and 4 white placebo film-coated tablets in row 4. The core of the tablet is coated.
Each of the 24 active tablet contains a small quantity of 2 different female hormones, called Drospirenone (Maxima MD) (a progestogen) and Ethinylestradiol (Maxima MD) (an estrogen). Due to the small quantity of the hormones, Maxima MD is considered a low-dose oral contraceptive. Since all tablets in the pack combine the same hormones in the same dose, it is considered a monophasic combined oral contraceptive.
The 4 tablets do not contain active ingredients and are called placebo tablets.
Maxima MD dosage
Take 1 tablet once daily, may be taken with food or without food, if necessary with a small amount of water. Maxima MD should be taken approximately the same time everyday. Always take Maxima MD exactly as the physician has recommended. Check and ask with the physician or pharmacist if unsure.
Each blister contains 24 active pink tablets and 4 white placebo tablets. The 2 different colored tablets are arranged in order. A strip contains 28 tablets. Do not get confused with the tablet, take a pink tablet for the first 24 days, and then a white tablet for the last 4 days. Then start a new strip straightaway (24 pink and then 4 white tablets). There is therefore, no gap between 2 strips. Because of the different composition of the tablets, it is necessary to begin with the 1st tablet on the upperleft and that tablets may be taken every day. For the correct order, the direction of the arrows on the strip must be followed. Preparation of the Strip:
During the 4 days when taking the white placebo tablets (the placebo days), bleeding should start (also called withdrawal bleeding). Normally, the period will begin on the 2nd or 3rd day after the last pink active tablet Maxima MD was taken. Once the last white tablet have been taken, the next strip should be started even if bleeding have not stopped. This means that the patient should start every strip on the same day of the week, and menstruation should occur during the same days of every month.
If Maxima MD was taken as indicated, there is protection against pregnancy for the 4 days the placebo tablets are taken.
Disposal: Medicines should not be disposed of via wastewater or household waste. Ask the pharmacist how to dispose medicines when no longer required. These measures will help to protect the environment.
Starting the 1st Strip: If the Patient Has Not Taken Any Hormonal Contraceptive in the Previous Month: Start taking Maxima MD on the 1st day of the cycle (the 1st day of menstruation). If the patient started taking on the 1st day of menstruation, there will be immediate protection against pregnancy. The patient can also start from the 2nd-5th day of the cycle, but an additional contraceptives (eg, a condom) should be used for the first 7 days.
Changing from a Combined Hormonal Contraceptive, Combined Contraceptive Vaginal Ring or Patch: Start taking Maxima MD preferably on the day after the last active tablet (the last tablet containing the active substances) of the previous pill, but at the latest on the day after the tablet-free days of the previous pill finish (or after taking the last inactive tablet of the previous pill). When changing from a combined contraceptive vaginal ring or patch, follow the physician's recommendations.
Changing from a Progestogen-Only-Method (Progestogen Only Tablet, Injection, Progestogen-Releasing IUD or Implant): The patient can change from the progestogen-only tablet whenever they like (if had an implant or an intrauterine device, use the new tablet the day it was removed; if an injection is used, use the new tablet on the day when the patient would have injected again), but it is recommended, in all cases, to use an additional protection (eg, a condom) for the first 7 days of taking Maxima MD.
After Miscarriage: Follow the physician's recommendations.
After Having a Baby: Start taking Maxima MD between 21 and 28 days after having a baby. If to start later than day 28, a barrier contraceptive (eg, a condom) must be used for the first 7 days of taking Maxima MD.
If, after having a baby and have had sex already before starting Maxima MD (again), be sure that the patient is not pregnant or wait for the next menstrual period.
If the patient is breastfeeding and wanted to start taking Maxima MD (again) after having a baby, see Use in pregnancy & lactation.
Vomiting or Severe Diarrhea: If vomiting occurs 3-4 hrs after taking an active pink tablet or severe diarrhea is present, there is a risk that the active ingredients in the pill have not been totally absorbed by the body. This is similar to what happens when forgotten to take a tablet. After vomiting or having diarrhea, another pink tablet from a reserve strip should be taken as soon as possible. If possible, take it within 12 hrs of the usual time, the tablet must be taken. If not possible or >12 hrs have passed, see Missed Dose as follows.
Delay of Menstrual Period: Although it is not recommended, period may be delayed (withdrawal bleeding) until the end of a new strip, if the white placebo tablets in the 4th row are not taken and a 2nd strip of Maxima MD is immediately started and finished. Specks (drops of blood or stains) or bleeding may be experienced when taking the 2nd strip. Finish the 2nd strip by taking the 4 white tablets from the 4th row. Then start the next strip.
Ask the physician for advice before deciding to delay menstrual period.
Changing the 1st Day of Period: If the tablets are taken according to the instructions, period (withdrawal bleeding) will start during the placebo days. If the patient have to change that day, it can be done by shortening (but never increasing - 4 is the maximum) the length of the placebo days. For example, if the placebo interval begins on Friday and if the patient wanted to start on Tuesday (3 days before), the patient should begin a new strip 3 days before as normally would. Withdrawal bleeding (a period) may not be experienced during this interval. But then, a light or menstruation-like bleeding may be experienced.
If unsure of what to do, consult a physician for advice.
Discontinuation of Maxima MD: Maxima MD may be discontinued whenever wanted. If the patient do not want to get pregnant, consult the physician about the other efficient birth control methods. If the patient wanted to become pregnant, discontinue Maxima MD and wait for the menstrual period before trying to become pregnant. The patient will be able to calculate the expected delivery date more easily.
Missed Dose: The last 4 tablets in the 4th row of the strip are placebo tablets. If forgotten to take 1 of these tablets, there will have no effect on the reliability of Maxima MD. Throw away the forgotten placebo.
If forgotten to take a pink, active tablet (tablets 1-24 of the blister-strip), follow these instructions: If <12 hrs late in taking a tablet, the protection from pregnancy is not reduced. Take the tablet as soon as realized and the following tablets at the usual time.
If >12 hours late in taking a tablet, protection from pregnancy may be reduced. The more tablets have forgotten to take, the greater the risk of becoming pregnant.
The risk of reduced protection against pregnancy is highest if forgotten to take a pink tablet at the beginning or at the end of the strip.
Consequently, the following measures should be adopted : Forgot to Take >1 Tablet in a Strip: Consult a physician.
Forgot to Take 1 Tablet Between Days 1–7 (1st Row): Take the forgotten tablet as soon as realized, even if this means that the 2 tablets must be taken at the same time. Continue taking the tablets at the usual time and additional precautions eg, a condom should be used for the next 7 days. If have had sex in the week before the tablet is forgotten, there is a risk for being pregnant. In this case, consult a physician.
Forgot to Take 1 Tablet Between Days 8–14 (2nd Row): Take the forgotten tablet as soon as realized, even if this means that the 2 tablets must be taken at the same time. Continue taking the tablets at the usual time. The contraceptive effect will not be reduced and should not be taken with additional precautions.
Forgot to Take 1 Tablet Between Days 15–24 (3rd or 4th Row): May choose 1 of the 2 following possibilities:
1. The tablet forgotten should be taken as soon as realized, even if this means that 2 tablets should be taken at the same time. Continue taking the following tablets at the usual time. Instead of having the white placebo tablets on this strip, throw away and start taking the next strip (the starting day will be different).
The patient will probably have period (withdrawal bleeding) at the end of the 2nd strip (while taking the white placebo tablets), but some specks or bleeding may occur when taking the active tablets of the 2nd strip.
2. The active pink tablets may also be discontinued and may directly take the 4 white placebo tablets, (before taking the placebo tablets, record the day the tablet was forgotten to be taken). If a new strip is to be started on a fixed start date, take the placebo white tablets for <4 days.
If 1 of these 2 recommendations are to be followed, the patient will be protected against pregnancy.
If forgotten to take a tablet in a strip, and there is no period during the placebo days, this could mean that the patient may be pregnant. In this case, consult the physician before continuing with the next strip.
Administration: Ask the physician for advice if not sure when to start. For any further questions on the use of Maxima MD, ask a physician or pharmacist.
Maxima MD interactions
Always inform the prescriber about the medications or herbal preparations the patient are taking. Also inform any other health professional that has prescribed other medication (or the pharmacist) that the patient is taking Maxima MD. The healthcare professional may inform the patient the need to use additional contraceptives (eg, condom) and inform the patient the duration.
Some medicine can cause Maxima MD to lose its contraceptive effect or can cause unexpected bleeding. This applies to medicines used to treat epilepsy (eg, primidone, phenytoin, barbiturates, carbamazepine, oxcarbazepine) and tuberculosis (eg, rifampicin), HIV (ritonavir), other infectious disease (griseofulvin, ampicillin, tetracyclines) and the medicinal herb St. John's wort.
If the patient wants to use herbal preparations which contain St. John's wort while taking Maxima MD, she should consult the doctor beforehand. Maxima MD can affect other medicines eg, those which contain ciclosporin or the anticonvulsant drug lamotrigine (this can increase the frequency of convulsions).
Consult the doctor or pharmacist before taking any medicine. Inform the doctor or pharmacist if the patient is taking or have recently taken any other medicines, including medicines obtained without a prescription.
Taking Maxima MD with Food and Drink: Take Maxima MD tablet everyday with some water if needed. The patient can take the tablets with or without food, but should take Maxima MD approximately at the same time everyday.
Laboratory Tests: If the patient need a blood analysis, inform the doctor or laboratory staff that the patient is taking a contraceptive, as oral contraceptives can affect the results of some test.
Maxima MD side effects
The following is a list of the side effects that have been linked with the use of Maxima MD: Common (between 1-10 in every 100 users may be affected): Mood swings, headache, nausea, breast pain, problem with periods eg, irregular menstruations and absence of periods.
Uncommon (between 1-10 in every 1000 users may be affected): Depression, loss of interest in sex, nervousness, sleepiness; dizziness, "pins and needles"; migraine, varicose veins, increased blood pressure; stomach ache, vomiting, indigestion, intestinal gas, inflammation of the stomach, diarrhea; acne, itching, rash; aches and pains eg, back pain, limb pain, muscular cramps; vaginal fungal infection, pelvic pain, breast enlargement, benign breast lumps, uterine/vaginal bleeding (which usually subsides during continued treatment), genital discharge, hot flushes, inflammation of the vagina (vaginitis), problems with periods; painful, reduced and very heavy periods; vaginal dryness, abnormal cervical smear; lack of energy, increased sweating, fluid retention, increased weight.
Rare (between 1-10 in every 10,000 users may be affected): Candida (fungal infection), anemia, increased number of platelets in the blood, allergic reaction, hormonal (endocrine) disorder; increased appetite, loss of appetite, abnormally high concentration of potassium in the blood, abnormally low concentration of sodium in the blood; failure to experience an orgasm, insomnia; giddiness, tremor; eye disorders eg, inflammation of the eyelid, dry eyes; abnormally rapid heartbeat, inflammation of a vein, nosebleed, fainting; enlarged abdomen, bowel disorder, feeling bloated, stomach hernia, fungal infection of the mouth, constipation, dry mouth; pain of bile ducts or gallbladder, inflammation of gallbladder; yellow-brown patches on the skin, eczema, hair loss; lumpy, light-sensitive and acne-like skin inflammation; dry skin, excessive hair growth, skin disorder, stretch marks on the skin, skin inflammation, skin nodules; difficult or painful sex, vaginal inflammation (vulvovaginitis), bleeding following intercourse, withdrawal bleeding, breast cyst, increased number of breast cells (hyperplasia), malignant breast lumps, abnormal growth on the mucosal surface of the neck of the womb, shrinkage or wasting of the lining of the womb, ovarian cysts, womb enlargement, feeling generally unwell, weight loss.
The following adverse effects have also been reported, but their frequency cannot be estimated from the available data: Hypersensitivity, erythema multiforme (rash with target-shaped reddening or sores).
If any of the adverse effects get serious, or if any side effects not listed is noticed, inform a physician or pharmacist.
Maxima MD contraindications
Hypersensitivity to Drospirenone (Maxima MD) or Ethinylestradiol (Maxima MD) or any other ingredient in Maxima MD. This could cause itching, a rash or inflammation.
Patients that have (or have had in the past) blood clots (thrombosis) in a blood vessel of the leg, lungs (embolsim) or other organs; a heart attack or stroke; any illness which could lead to a heart attack (eg, angina pectoris which causes serious pain in the chest) or a stroke (eg, a temporary or minor stroke without residual effects); certain form of migraine (focal neurological symptoms); inflammation of the pancreas (pancreatitis); liver illness and hepatic function have not yet normalized; kidneys do not work well (kidney failure); liver tumor; suspect breast cancer or cancer of the sexual organs.
Any illness which could increase the risk of developing artery thrombosis eg, diabetes with damaged blood vessels, very high blood pressure, very high fat levels in the blood (cholesterol or triglycerides); disturbance of blood clotting (eg, protein C deficiency); vaginal bleeding and the cause is unknown.
Use in pregnancy: If the patient is pregnant, do not take Maxima MD. If the patient is pregnant when taking Maxima MD, stop taking it immediately and contact the doctor.
Consult the doctor or pharmacist before taking any medicine.
Active ingredient matches for Maxima MD:
Drospirenone/Ethinylestradiol in Argentina.
List of Maxima MD substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Maxima MD 24 (Argentina) | |
| Megy (Brazil) | |
| Miafem (Chile) | |
| Tablet, Film-Coated; Oral; Drospirenone 3 mg; Ethinyl Estradiol 0.02 mg | |
| Tablet, Film-Coated; Oral; Drospirenone 3 mg; Ethinyl Estradiol 0.03 mg | |
| Miafem CD (Chile) | |
| Midiana (Bulgaria, Estonia, Georgia) | |
| Midiana 28 (Bulgaria, Sweden) | |
| Midrospa (Germany) | |
| MinayEight (Estonia) | |
| Modolew (Netherlands, Poland) | |
| Movinella (Denmark) | |
| Mya (Canada) | |
| Mylaz (Slovakia) | |
| Mylazelle (Slovakia) | |
| Myline (Slovakia) | |
| MYWY (Bulgaria, Germany) | |
| Naraya (Poland) | |
| Naraya Plus (Poland) | |
| Nelecta (Portugal) | |
| Niki (Brazil) | |
| NubeIght (Estonia) | |
| Nyssiela (Bosnia & Herzegowina, Czech Republic) | |
| Okade (Netherlands) | |
| Orindille (Estonia) | |
| Orlyelle (Netherlands) | |
| Palandra (Bulgaria, Estonia, Malta) | |
| Perliq (Italy) | |
| Perynella (Belgium) | |
| Perynella 0.02mg/3ml (Luxembourg) | |
| Petibelle (Germany) | |
| Tablet, Film-Coated; Oral; Drospirenone; Ethinyl Estradiol (Jenapharm) | |
| Pirestrol (Estonia) | |
| Prevyasm (Brazil) | |
| Protimest (Colombia) | |
| Radiance (Mexico) | |
| Radiance Marine protein 105 mg, ubidecarenone 15 mg, camelliasinensis leaves 150 mg, vitisvinifera 25 mg, pinus pinasterbark extract 20 mg, citrusbioflavonoids 50 mg, Naturalvitamin E 10 IU, betacarotene3 mg, selenium 26 mcg, zinc 14mg, lycopene 5.85 g, lu (Universal) | $ 2.18 |
| Radiance Marine protein 105 mg, ubidecarenone 15 mg, camelliasinensis leaves 150 mg, vitisvinifera 25 mg, pinus pinasterbark extract 20 mg, citrusbioflavonoids 50 mg, Naturalvitamin E 10 IU, betacarotene3 mg, selenium 26 mcg, zinc 14mg, lycopene 5.85 g, lu (Universal) | $ 2.18 |
| Radiance Marine protein 105 mg, ubidecarenone 15 mg, camelliasinensis leaves 150 mg, vitisvinifera 25 mg, pinus pinasterbark extract 20 mg, citrusbioflavonoids 50 mg, Naturalvitamin E 10 IU, betacarotene3 mg, selenium 26 mcg, zinc 14mg, lycopene 5.85 g, lu (Universal) | $ 2.18 |
| Radiance Marine protein 105 mg, ubidecarenone 15 mg, camelliasinensis leaves 150 mg, vitisvinifera 25 mg, pinus pinasterbark extract 20 mg, citrusbioflavonoids 50 mg, Naturalvitamin E 10 IU, betacarotene3 mg, selenium 26 mcg, zinc 14mg, lycopene 5.85 g, lu (Universal) | $ 2.18 |
| Radiance Marine protein 105 mg, ubidecarenone 15 mg, camelliasinensis leaves 150 mg, vitisvinifera 25 mg, pinus pinasterbark extract 20 mg, citrusbioflavonoids 50 mg, Naturalvitamin E 10 IU, betacarotene3 mg, selenium 26 mcg, zinc 14mg, lycopene 5.85 g, lu (Universal) | $ 2.18 |
| Radiance Marine protein 105 mg, ubidecarenone 15 mg, camelliasinensis leaves 150 mg, vitisvinifera 25 mg, pinus pinasterbark extract 20 mg, citrusbioflavonoids 50 mg, Naturalvitamin E 10 IU, betacarotene3 mg, selenium 26 mcg, zinc 14mg, lycopene 5.85 g, lu (Universal) | $ 2.18 |
| Radiance Marine protein 105 mg, ubidecarenone 15 mg, camelliasinensis leaves 150 mg, vitisvinifera 25 mg, pinus pinasterbark extract 20 mg, citrusbioflavonoids 50 mg, Naturalvitamin E 10 IU, betacarotene3 mg, selenium 26 mcg, zinc 14mg, lycopene 5.85 g, lu (Universal) | $ 2.18 |
| RADIANCE soft-gelatin cap 15's (Universal) | $ 2.18 |
| Radiance Marine protein 105 mg, ubidecarenone 15 mg, camelliasinensis leaves 150 mg, vitisvinifera 25 mg, pinus pinasterbark extract 20 mg, citrusbioflavonoids 50 mg, Naturalvitamin E 10 IU, betacarotene3 mg, selenium 26 mcg, zinc 14mg, lycopene 5.85 g, lu (Universal) | $ 2.18 |
See 481 substitutes for Maxima MD | |
References
- DailyMed. "DROSPIRENONE; ETHINYL ESTRADIOL; LEVOMEFOLATE CALCIUM: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "Drospirenone". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "Drospirenone". http://www.drugbank.ca/drugs/DB01395 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Maxima MD are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Maxima MD. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
