What is Nitidex?
Nitidex is a selective serotonin and norepinephrine reuptake inhibitor antidepressant (SSNRI). Nitidex affects chemicals in the brain that may become unbalanced and cause depression.
Nitidex is used to treat major depressive disorder in adults. Nitidex is also used to treat general anxiety disorder in adults and children who are at least 7 years old.
Nitidex is also used in adults to treat fibromyalgia (a chronic pain disorder), or chronic muscle or joint pain (such as low back pain and osteoarthritis pain).
Nitidex is also used to treat pain caused by nerve damage in adults with diabetes (diabetic neuropathy).
Nitidex may also be used for purposes not listed in this medication guide.
Nitidex indications
Nitidex® is indicated for the treatment of:
- Major Depressive Disorder
- Generalized Anxiety Disorder
- Diabetic Peripheral Neuropathy
- Fibromyalgia
- Chronic Musculoskeletal Pain
How should I use Nitidex?
Use Nitidex delayed-release capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Nitidex delayed-release capsules comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Nitidex delayed-release capsules refilled.
- Take Nitidex delayed-release capsules by mouth with or without food. Taking it with food may help to decrease the chance of nausea or stomach upset.
- Swallow Nitidex delayed-release capsules whole. Do not break, crush, or chew before swallowing. Do not open the capsule and sprinkle the contents on food or in liquid.
- Take Nitidex delayed-release capsules on a regular schedule to get the most benefit from it. Taking Nitidex delayed-release capsules at the same time each day will help you remember to take it.
- Continue to take Nitidex delayed-release capsules even if you feel well. Do not miss any doses.
- Do not suddenly stop taking Nitidex delayed-release capsules without checking with your doctor. Side effects may occur. They may include anxiety, numbness or tingling of the skin, diarrhea, dizziness, headache, increased sweating, irritability, nausea, trouble sleeping, unusual tiredness, or vomiting. If you need to stop Nitidex delayed-release capsules, your doctor may need to gradually lower your dose.
- If you miss a dose of Nitidex delayed-release capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Nitidex delayed-release capsules.
Uses of Nitidex in details
Use: Labeled Indications
Fibromyalgia (delayed-release particles capsule only): Management of fibromyalgia.
Generalized anxiety disorder: Treatment of generalized anxiety disorder.
Major depressive disorder (unipolar): Treatment of unipolar major depressive disorder.
Musculoskeletal pain, chronic: Management of chronic musculoskeletal pain including osteoarthritis of the knee and low back pain.
Neuropathic pain associated with diabetes mellitus: Management of pain associated with diabetic peripheral neuropathy.
Off Label Uses
Chemotherapy-induced peripheral neuropathy
Data from a randomized, double-blind, placebo-controlled study support the use of Nitidex in the treatment of pain, numbness, and tingling associated with chemotherapy-induced peripheral neuropathy. Subgroup analyses suggest efficacy may be greater for oxaliplatin-induced neuropathy as opposed to paclitaxel-induced neuropathy
American College of Physicians (ACP) guidelines on nonsurgical management of urinary incontinence recommend against pharmacologic therapy in women with stress urinary incontinence and note that although low-quality, placebo-controlled studies of Nitidex demonstrate beneficial effects, these effects have not been confirmed by data from high-quality studies.
National Institute for Health and Care Excellence (NICE) evidence-based guidelines on the management of urinary incontinence and pelvic organ prolapse in women state that Nitidex should not be considered as first-line treatment for women with predominant stress urinary incontinence nor routinely used as second-line treatment for women with stress urinary incontinence. However, Nitidex may be considered as second-line therapy for women who decline surgical treatment or who are not suitable candidates for surgical treatment.
Nitidex description
The active ingredient in Nitidex is Nitidex.
Each Nitidex 30 mg & 60 mg capsule contains 30 mg & 60 mg of Nitidex as Nitidex hydrochloride respectively.
Excipients/Inactive Ingredients: Capsule Content: Hypromellose, hypromellose acetate succinate, sucrose, sugar spheres, talc, titanium dioxide (E171), triethyl citrate. Capsule Shell:
60 mg: Gelatin, sodium lauryl sulfate, titanium dioxide (E171), indigo carmine (E132), yellow iron oxide (E172), edible white ink.
Edible Green Ink Contains: Black Iron Oxide-Synthetic (E172), yellow iron oxide-synthetic (E172), propylene glycol, shellac.
Edible White Ink Contains: Titanium Dioxide (E171), propylene glycol, shellac, povidone.
Nitidex dosage
Nitidex Dosage
Generic name: Nitidex HYDROCHLORIDE 40mg
Dosage form: capsule, delayed release
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Swallow Nitidex whole. Do not chew or crush. Do not open the capsule and sprinkle its contents on food or mix with liquids. All of these might affect the enteric coating. Nitidex can be given without regard to meals. If a dose of Nitidex is missed, take the missed dose as soon as it is remembered. If it is almost time for the next dose, skip the missed dose and take the next dose at the regular time. Do not take two doses of Nitidex at the same time.
Dosage for Treatment of Major Depressive Disorder
Administer Nitidex at a total dose of 40 mg/day (given as 20 mg twice daily) to 60 mg/day (given either once daily or as 30 mg twice daily). For some patients, it may be desirable to start at 30 mg once daily for 1 week, to allow patients to adjust to the medication before increasing to 60 mg once daily. While a 120 mg/day dose was shown to be effective, there is no evidence that doses greater than 60 mg/day confer any additional benefits. The safety of doses above 120 mg/day has not been adequately evaluated. Periodically reassess to determine the need for maintenance treatment and the appropriate dose for such treatment.
Dosage for Treatment of Generalized Anxiety Disorder
Adults
For most patients, initiate Nitidex 60 mg once daily. For some patients, it may be desirable to start at 30 mg once daily for 1 week, to allow patients to adjust to the medication before increasing to 60 mg once daily. While a 120 mg once daily dose was shown to be effective, there is no evidence that doses greater than 60 mg/day confer additional benefit. Nevertheless, if a decision is made to increase the dose beyond 60 mg once daily, increase dose in increments of 30 mg once daily. The safety of doses above 120 mg once daily has not been adequately evaluated. Periodically reassess to determine the continued need for maintenance treatment and the appropriate dose for such treatment.
Elderly
Initiate Nitidex at a dose of 30 mg once daily for 2 weeks before considering an increase to the target dose of 60 mg. Thereafter, patients may benefit from doses above 60 mg once daily. If a decision is made to increase the dose beyond 60 mg once daily, increase dose in increments of 30 mg once daily. The maximum dose studied was 120 mg per day. Safety of doses above 120 mg once daily has not been adequately evaluated.
Children and Adolescents (7 to 17 years of age)
Initiate Nitidex at a dose of 30 mg once daily for 2 weeks before considering an increase to 60 mg. The recommended dose range is 30 to 60 mg once daily. Some patients may benefit from doses above 60 mg once daily. If a decision is made to increase the dose beyond 60 mg once daily, increase dose in increments of 30 mg once daily. The maximum dose studied was 120 mg per day. The safety of doses above 120 mg once daily has not been evaluated.
Dosage for Treatment of Diabetic Peripheral Neuropathic Pain
Administer Nitidex 60 mg once daily. There is no evidence that doses higher than 60 mg confer additional significant benefit and the higher dose is clearly less well tolerated. For patients for whom tolerability is a concern, a lower starting dose may be considered.
Since diabetes is frequently complicated by renal disease, consider a lower starting dose and gradual increase in dose for patients with renal impairment.
Dosage for Treatment of Chronic Musculoskeletal Pain
Administer Nitidex 60 mg once daily. Begin treatment at 30 mg for one week, to allow patients to adjust to the medication before increasing to 60 mg once daily. There is no evidence that higher doses confer additional benefit, even in patients who do not respond to a 60 mg dose, and higher doses are associated with a higher rate of adverse reactions.
Dosing in Special Populations
Hepatic Impairment
Avoid use in patients with chronic liver disease or cirrhosis.
Severe Renal Impairment
Avoid use in patients with severe renal impairment, GFR <30 mL/min.
Discontinuing Nitidex
Adverse reactions after discontinuation of Nitidex, after abrupt or tapered discontinuation, include: dizziness, headache, nausea, diarrhea, paresthesia, irritability, vomiting, insomnia, anxiety, hyperhidrosis, and fatigue. A gradual reduction in dosage rather than abrupt cessation is recommended whenever possible.
Switching a Patient to or from a Monoamine Oxidase Inhibitor (MAOI) Intended to Treat Psychiatric Disorders
At least 14 days should elapse between discontinuation of an MAOI intended to treat psychiatric disorders and initiation of therapy with Nitidex. Conversely, at least 5 days should be allowed after stopping Nitidex before starting an MAOI intended to treat psychiatric disorders.
Use of Nitidex with Other MAOIs such as Linezolid or Methylene Blue
Do not start Nitidex in a patient who is being treated with linezolid or intravenous methylene blue because there is an increased risk of serotonin syndrome. In a patient who requires more urgent treatment of a psychiatric condition, other interventions, including hospitalization, should be considered.
In some cases, a patient already receiving Nitidex therapy may require urgent treatment with linezolid or intravenous methylene blue. If acceptable alternatives to linezolid or intravenous methylene blue treatment are not available and the potential benefits of linezolid or intravenous methylene blue treatment are judged to outweigh the risks of serotonin syndrome in a particular patient, Nitidex should be stopped promptly, and linezolid or intravenous methylene blue can be administered. The patient should be monitored for symptoms of serotonin syndrome for 5 days or until 24 hours after the last dose of linezolid or intravenous methylene blue, whichever comes first. Therapy with Nitidex may be resumed 24 hours after the last dose of linezolid or intravenous methylene blue.
The risk of administering methylene blue by non-intravenous routes (such as oral tablets or by local injection) or in intravenous doses much lower than 1 mg/kg with Nitidex is unclear. The clinician should, nevertheless, be aware of the possibility of emergent symptoms of serotonin syndrome with such use.
More about Nitidex (Nitidex)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Espanol
- 0 Reviews - Add your own review/rating
Consumer resources
- Nitidex
- Nitidex (Advanced Reading)
- Other brands: Nitidex
Professional resources
- Nitidex (FDA)
- Nitidex (AHFS Monograph)
Related treatment guides
- Back Pain
- Chronic Pain
- Depression
- Diabetic Peripheral Neuropathy
- Generalized Anxiety Disorder
- More (1) »
Nitidex interactions
See also:
What other drugs will affect Nitidex?
Potential for Other Drugs to Affect Nitidex
Both CYP1A2 and CYP2D6 are responsible for Nitidex metabolism
Inhibitors of CYP1A2 Concomitant use of Nitidex with fluvoxamine, an inhibitor of CYP1A2, results in approximately a 6-fold increase in AUC and about a 2.5-fold increase in Cmax of Nitidex. Some quinolone antibiotics would be expected to have similar effects and these combinations should be avoided
Inhibitors of CYP2D6 Because CYP2D6 is involved in Nitidex metabolism, concomitant use of Nitidex with potent inhibitors of CYP2D6 may result in higher concentrations of Nitidex. Paroxetine (20 mg QD) increased the concentration of Nitidex (40 mg QD) by about 60%, and greater degrees of inhibition are expected with higher doses of paroxetine. Similar effects would be expected with other potent CYP2D6 inhibitors (e.g., fluoxetine, quinidine).
Potential for Nitidex to Affect Other Drugs
Drugs Metabolized by CYP1A2 In vitro drug interaction studies demonstrate that Nitidex does not induce CYP1A2 activity, and it is unlikely to have a clinically significant effect on the metabolism of CYP1A2 substrates.
Drugs Metabolized by CYP2D6 Nitidex is a moderate inhibitor of CYP2D6. When Nitidex was administered (at a dose of 60 mg BID) in conjunction with a single 50-mg dose of desipramine, a CYP2D6 substrate, the AUC of desipramine increased 3-fold. Therefore, co-administration of Nitidex with other drugs that are extensively metabolized by this isozyme and which have a narrow therapeutic index, including certain antidepressants (tricyclic antidepressants [TCAs], such as nortriptyline, amitriptyline, and imipramine), phenothiazines and Type 1C antiarrhythmics (e.g., propafenone, flecainide), should be approached with caution. Plasma TCA concentrations may need to be monitored and the dose of the TCA may need to be reduced if a TCA is co-administered with Nitidex. Because of the risk of serious ventricular arrhythmias and sudden death potentially associated with elevated plasma levels of thioridazine, Nitidex and thioridazine should not be co-administered.
Drugs Metabolized by CYP3A Results of in vitro studies demonstrate that Nitidex does not inhibit or induce CYP3A activity.
Nitidex May Have a Clinically Important Interaction with the Following Other Drugs:
Alcohol When Nitidex and ethanol were administered several hours apart so that peak concentrations of each would coincide, Nitidex did not increase the impairment of mental and motor skills caused by alcohol.
In the Nitidex clinical trials database, three Nitidex-treated patients had liver injury as manifested by ALT and total bilirubin elevations, with evidence of obstruction. Substantial intercurrent ethanol use was present in each of these cases, and this may have contributed to the abnormalities seen
CNS Acting Drugs Given the primary CNS effects of Nitidex, it should be used with caution when it is taken in combination with or substituted for other centrally acting drugs, including those with a similar mechanism of action.
Potential for Interaction with Drugs that Affect Gastric Acidity Nitidex has an enteric coating that resists dissolution until reaching a segment of the gastrointestinal tract where the pH exceeds 5.5. In extremely acidic conditions, Nitidex, unprotected by the enteric coating, may undergo hydrolysis to form naphthol. Caution is advised in using Nitidex in patients with conditions that may slow gastric emptying (e.g., some diabetics). Drugs that raise the gastrointestinal pH may lead to an earlier release of Nitidex. However, co-administration of Nitidex with aluminum- and magnesium-containing antacids (51 mEq) or Nitidex with famotidine, had no significant effect on the rate or extent of Nitidex absorption after administration of a 40-mg oral dose. It is unknown whether the concomitant administration of proton pump inhibitors affects Nitidex absorption.
Nitidex side effects
See also:
What are the possible side effects of Nitidex?
The following serious adverse reactions are described below and elsewhere in the labeling:
- Suicidal Thoughts and Behaviors in Children, Adolescents and Young Adults
- Hepatotoxicity
- Orthostatic Hypotension, Falls and Syncope
- Serotonin Syndrome
- Abnormal Bleeding
- Severe Skin Reactions
- Discontinuation of Treatment with Nitidex
- Activation of Mania/Hypomania
- Angle-Closure Glaucoma
- Seizures
- Effect on Blood Pressure
- Clinically Important Drug Interactions
- Hyponatremia
- Urinary Hesitation and Retention
Clinical Trial Data Sources
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.
The stated frequencies of adverse reactions represent the proportion of individuals who experienced, at least once, a treatment-emergent adverse reaction of the type listed. A reaction was considered treatment-emergent if it occurred for the first time or worsened while receiving therapy following baseline evaluation. Reactions reported during the studies were not necessarily caused by the therapy, and the frequencies do not reflect investigator impression (assessment) of causality.
Adults
The data described below reflect exposure to Nitidex in placebo-controlled trials for MDD (N=3779), GAD (N=1018), OA (N=503), CLBP (N=600), DPNP (N=906), and FM (N=1294). The population studied was 17 to 89 years of age; 65.7%, 60.8%, 60.6%, 42.9%, and 94.4% female; and 81.8%, 72.6%, 85.3%, 74.0%, and 85.7% Caucasian for MDD, GAD, OA and CLBP, DPNP, and FM, respectively. Most patients received doses of a total of 60 to 120 mg per day. The data below do not include results of the trial examining the efficacy of Nitidex in patients ≥ 65 years old for the treatment of generalized anxiety disorder; however, the adverse reactions observed in this geriatric sample were generally similar to adverse reactions in the overall adult population.
Children And Adolescents
The data described below reflect exposure to Nitidex in pediatric, 10-week, placebo-controlled trials for MDD (N=341) and GAD (N=135). The population studied (N=476) was 7 to 17 years of age with 42.4% children age 7 to 11 years of age, 50.6% female, and 68.6% white. Patients received 30-120 mg per day during placebo-controlled acute treatment studies. Additional data come from the overall total of 822 pediatric patients (age 7 to 17 years of age) with 41.7% children age 7 to 11 years of age and 51.8% female exposed to Nitidex in MDD and GAD clinical trials up to 36-weeks in length, in which most patients received 30-120 mg per day.
Adverse Reactions Reported As Reasons For Discontinuation Of Treatment In Adult Placebo-Controlled Trials
Major Depressive Disorder
Approximately 8.4% (319/3779) of the patients who received Nitidex in placebo-controlled trials for MDD discontinued treatment due to an adverse reaction, compared with 4.6% (117/2536) of the patients receiving placebo. Nausea (Nitidex 1.1%, placebo 0.4%) was the only common adverse reaction reported as a reason for discontinuation and considered to be drug-related (i.e., discontinuation occurring in at least 1% of the Nitidex-treated patients and at a rate of at least twice that of placebo).
Generalized Anxiety Disorder
Approximately 13.7% (139/1018) of the patients who received Nitidex in placebo-controlled trials for GAD discontinued treatment due to an adverse reaction, compared with 5.0% (38/767) for placebo. Common adverse reactions reported as a reason for discontinuation and considered to be drug-related (as defined above) included nausea (Nitidex 3.3%, placebo 0.4%), and dizziness (Nitidex 1.3%, placebo 0.4%).
Diabetic Peripheral Neuropathic Pain
Approximately 12.9% (117/906) of the patients who received Nitidex in placebo-controlled trials for DPNP discontinued treatment due to an adverse reaction, compared with 5.1% (23/448) for placebo. Common adverse reactions reported as a reason for discontinuation and considered to be drug-related (as defined above) included nausea (Nitidex 3.5%, placebo 0.7%), dizziness (Nitidex 1.2%, placebo 0.4%), and somnolence (Nitidex 1.1%, placebo 0.0%).
Fibromyalgia
Approximately 17.5% (227/1294) of the patients who received Nitidex in 3 to 6 month placebo-controlled trials for FM discontinued treatment due to an adverse reaction, compared with 10.1% (96/955) for placebo. Common adverse reactions reported as a reason for discontinuation and considered to be drug-related (as defined above) included nausea (Nitidex 2.0%, placebo 0.5%), headache (Nitidex 1.2%, placebo 0.3%), somnolence (Nitidex 1.1%, placebo 0.0%), and fatigue (Nitidex 1.1%, placebo 0.1%).
Chronic Pain Due To Osteoarthritis
Approximately 15.7% (79/503) of the patients who received Nitidex in 13-week, placebo-controlled trials for chronic pain due to OA discontinued treatment due to an adverse reaction, compared with 7.3% (37/508) for placebo. Common adverse reactions reported as a reason for discontinuation and considered to be drug-related (as defined above) included nausea (Nitidex 2.2%, placebo 1.0%).
Chronic Low Back Pain
Approximately 16.5% (99/600) of the patients who received Nitidex in 13-week, placebo-controlled trials for CLBP discontinued treatment due to an adverse reaction, compared with 6.3% (28/441) for placebo. Common adverse reactions reported as a reason for discontinuation and considered to be drug-related (as defined above) included nausea (Nitidex 3.0%, placebo 0.7%), and somnolence (Nitidex 1.0%, placebo 0.0%).
Most Common Adult Adverse Reactions
Pooled Trials For All Approved Indications
The most commonly observed adverse reactions in Nitidex-treated patients (incidence of at least 5% and at least twice the incidence in placebo patients) were nausea, dry mouth, somnolence, constipation, decreased appetite, and hyperhidrosis.
Diabetic Peripheral Neuropathic Pain
The most commonly observed adverse reactions in Nitidex-treated patients (as defined above) were nausea, somnolence, decreased appetite, constipation, hyperhidrosis, and dry mouth.
Fibromyalgia
The most commonly observed adverse reactions in Nitidex-treated patients (as defined above) were nausea, dry mouth, constipation, somnolence, decreased appetite, hyperhidrosis, and agitation.
Chronic Pain Due To Osteoarthritis
The most commonly observed adverse reactions in Nitidex-treated patients (as defined above) were nausea, fatigue, constipation, dry mouth, insomnia, somnolence, and dizziness.
Chronic Low Back Pain
The most commonly observed adverse reactions in Nitidex-treated patients (as defined above) were nausea, dry mouth, insomnia, somnolence, constipation, dizziness, and fatigue.
Adverse Reactions Occurring At An Incidence Of 5% Or More Among Nitidex-Treated Patients In Adult Placebo-Controlled Trials
Table 2 gives the incidence of treatment-emergent adverse reactions in placebo-controlled trials for approved indications that occurred in 5% or more of patients treated with Nitidex and with an incidence greater than placebo.
Table 2: Treatment-Emergent Adverse Reactions: Incidence of 5% or More and Greater than Placebo in Placebo-Controlled Trials of Approved Indications Also includes initial insomnia, insomnia, middle insomnia, and terminal insomnia.
Other adverse reactions that occurred at an incidence of less than 2% but were reported by more Nitidex treated patients than placebo treated patients and are associated Nitidex treatment: abnormal dreams (including nightmare), anxiety, flushing (including hot flush), hyperhidrosis, palpitations, pulse increased, and tremor.
Discontinuation-emergent symptoms have been reported when stopping Nitidex. The most commonly reported symptoms following discontinuation of Nitidex in pediatric clinical trials have included headache, dizziness, insomnia, and abdominal pain.
Growth (Height and Weight)
Decreased appetite and weight loss have been observed in association with the use of SSRIs and SNRIs. Pediatric patients treated with Nitidex in clinical trials experienced a 0.1kg mean decrease in weight at 10 weeks, compared with a mean weight gain of approximately 0.9 kg in placebo-treated patients. The proportion of patients who experienced a clinically significant decrease in weight ( ≥ 3.5%) was greater in the Nitidex group than in the placebo group (14% and 6%, respectively). Subsequently, over the 4- to 6-month uncontrolled extension periods, Nitidex-treated patients on average trended toward recovery to their expected baseline weight percentile based on population data from age- and sex-matched peers. In studies up to 9 months, Nitidex-treated pediatric patients experienced an increase in height of 1.7 cm on average (2.2 cm increase in children [7 to 11 years of age] and 1.3 cm increase in adolescents [12 to 17 years of age]). While height increase was observed during these studies, a mean decrease of 1% in height percentile was observed (decrease of 2% in children [7 to 11 years of age] and increase of 0.3% in adolescents [12 to 17 years of age]). Weight and height should be monitored regularly in children and adolescents treated with Nitidex.
Postmarketing Spontaneous Reports
The following adverse reactions have been identified during post approval use of Nitidex. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.
Adverse reactions reported since market introduction that were temporally related to Nitidex therapy and not mentioned elsewhere in labeling include: acute pancreatitis, anaphylactic reaction, aggression and anger (particularly early in treatment or after treatment discontinuation), angioneurotic edema, angle-closure glaucoma, colitis (microscopic or unspecified), cutaneous vasculitis (sometimes associated with systemic involvement), extrapyramidal disorder, galactorrhea, gynecological bleeding, hallucinations, hyperglycemia, hyperprolactinemia, hypersensitivity, hypertensive crisis, muscle spasm, rash, restless legs syndrome, seizures upon treatment discontinuation, supraventricular arrhythmia, tinnitus (upon treatment discontinuation), trismus, and urticaria.
Nitidex contraindications
See also:
What is the most important information I should know about Nitidex?
Hypersensitivity to active substance or to any of the excipients.
Concomitant use of Nitidex with nonselective, irreversible monoamine oxidase inhibitors (MAOIs).
Liver disease resulting in hepatic impairment.
Nitidex should not be used in combination with fluvoxamine, ciprofloxacin or enoxacine (i.e. potent CYP1A2 inhibitors) since the combination results in elevated plasma concentrations of Nitidex.
Severe renal impairment (creatine clearance <30 mL/min).
The initiation of treatment with Nitidex is contraindicated in patients with uncontrolled hypertension that could expose patients to a potential risk of hypertensive crisis.
Active ingredient matches for Nitidex:
Duloxetine in Argentina.
List of Nitidex substitutes (brand and generic names) | Sort by popularity |
Unit description / dosage (Manufacturer) | Price, USD |
Nitexol (Chile) | |
Capsule, Enteric Coated; Oral; Duloxetine Hydrochloride 60 mg | |
Onelar (Croatia (Hrvatska), Estonia, Greece, Lithuania, Malta, Netherlands, Romania) | |
Onelar 30mg (Bulgaria) | |
Onelar 60mg (Bulgaria) | |
Pharmacor Duloxetine (Australia) | |
PMS-Duloxetine (Canada) | |
PMS-duloxetine capsule / delayed release 30 mg (Pharmascience Inc (Canada)) | |
PMS-duloxetine capsule / delayed release 60 mg (Pharmascience Inc (Canada)) | |
RAN-Duloxetine (Canada) | |
Ran-duloxetine capsule / delayed release 30 mg (Ranbaxy Pharmaceuticals Canada Inc. (Canada)) | |
Ran-duloxetine capsule / delayed release 60 mg (Ranbaxy Pharmaceuticals Canada Inc. (Canada)) | |
Realta (Chile) | |
Riva-Duloxetine (Canada) | |
Riva-duloxetine capsule / delayed release 30 mg (Laboratoire Riva Inc (Canada)) | |
Riva-duloxetine capsule / delayed release 60 mg (Laboratoire Riva Inc (Canada)) | |
Roxanri (Bosnia & Herzegowina) | |
Sandoz Duloxetine (Canada) | |
Sandoz Duloxetine capsule / delayed release 30 mg (Sandoz Canada Incorporated (Canada)) | |
Sandoz Duloxetine capsule / delayed release 60 mg (Sandoz Canada Incorporated (Canada)) | |
Sebata (South Korea) | |
Siloxezol (Italy, Sweden) | |
Swenta (India) | |
Swenta 20mg TAB (Triton (Calyx)) | |
Swenta 30mg TAB (Triton (Calyx)) | |
20 mg (Triton (Calyx)) | |
30 mg (Triton (Calyx)) | |
SWENTA 20MG TABLET 1 strip / 10 tablets each (Triton (Calyx)) | $ 0.82 |
SWENTA tab 20 mg x 10's (Triton (Calyx)) | $ 0.84 |
SWENTA tab 30 mg x 10's (Triton (Calyx)) | $ 0.76 |
Swenta 20mg Tablet (Triton (Calyx)) | $ 0.08 |
Sylonex (India) | |
Sylonex 20mg EC-TAB / 100 (Psyco Remedies.) | $ 5.80 |
Sylonex 30mg EC-TAB / 100 (Psyco Remedies.) | $ 9.22 |
Sylonex 40mg EC-TAB / 100 (Psyco Remedies.) | $ 10.65 |
Sylonex 60mg EC-TAB / 100 (Psyco Remedies.) | $ 16.27 |
20 mg x 100's (Psyco Remedies.) | $ 5.80 |
30 mg x 100's (Psyco Remedies.) | $ 9.22 |
40 mg x 100's (Psyco Remedies.) | $ 10.65 |
60 mg x 100's (Psyco Remedies.) | $ 16.27 |
Sylonex 30 mg Tablet (Psyco Remedies.) | $ 0.09 |
Sylonex 40 mg Tablet (Psyco Remedies.) | $ 0.11 |
Sylonex 60 mg Tablet (Psyco Remedies.) | $ 0.16 |
Sylonex 20 mg Tablet (Psyco Remedies.) | $ 0.06 |
SYLONEX 30MG CAPSULE 1 strip / 10 capsules each (Psyco Remedies.) | $ 0.93 |
SYLONEX enteric-coated tab 20 mg x 10's (Psyco Remedies.) | $ 0.64 |
SYLONEX enteric-coated tab 30 mg x 10's (Psyco Remedies.) | $ 0.95 |
SYLONEX enteric-coated tab 40 mg x 10's (Psyco Remedies.) | $ 1.14 |
SYLONEX enteric-coated tab 60 mg x 10's (Psyco Remedies.) | $ 1.63 |
See 903 substitutes for Nitidex |
References
- PubChem. "duloxetine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "duloxetine". http://www.drugbank.ca/drugs/DB00476 (accessed September 17, 2018).
- MeSH. "Serotonin and Noradrenaline Reuptake Inhibitors". https://www.ncbi.nlm.nih.gov/mesh/20... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Nitidex are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Nitidex. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yet1 consumer reported age
Users | % | ||
---|---|---|---|
46-60 | 1 | 100.0% |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology