• Symax Duotab indications
• Uses of Symax Duotab in details
• Symax Duotab description
• Symax Duotab dosage
• Symax Duotab interactions
• Symax Duotab side effects
• Symax Duotab contraindications

What is Symax Duotab?

Symax Duotab produces many effects in the body, including relief from muscle spasms.

Symax Duotab also reduces the fluid secretions of many organs and glands in the body, such as the stomach, pancreas, lungs, saliva glands, sweat glands, and nasal passages.

Symax Duotab is used to treat many different stomach and intestinal disorders, including peptic ulcer and irritable bowel syndrome. It is also used to control muscle spasms in the bladder, kidneys, or digestive tract, and to reduce stomach acid. Symax Duotab is sometimes used to reduce tremors and rigid muscles in people with symptoms of Parkinson's disease.

Symax Duotab is also used as a drying agent to control excessive salivation, runny nose, or excessive sweating.

Symax Duotab may also be used for purposes not listed in this medication guide.

Symax Duotab indications

Symax Duotab® is effective as adjunctive therapy in the treatment of peptic ulcer. In acute episodes, Symax Duotab® injection can be used to control gastric secretion, visceral spasm and hypermotility in spastic colitis, spastic bladder, cystitis, pylorospasm, and associated abdominal cramps. For use as adjunctive therapy in the treatment of irritable bowel syndrome (irritable colon, spastic colon, mucous colitis) and functional gastrointestinal disorders. Also as adjunctive therapy in the treatment of neurogenic bladder and neurogenic bowel disturbances (including the splenic flexure syndrome and neurogenic colon).

Parenterally administered Symax Duotab® is also effective in reducing gastrointestinal motility to facilitate diagnostic procedures such as endoscopy or hypotonic duodenography. Symax Duotab® may be used to reduce pain and hypersecretion in pancreatitis, in certain cases of partial heart block associated with vagal activity, and as an antidote for poisoning by anticholinesterase agents.

IN ANESTHESIA:

Symax Duotab® injection is indicated as a pre-operative antimuscarinic to reduce salivary, tracheobronchial, and pharyngeal secretions, to reduce the volume and acidity of gastric secretions, and to block cardiac vagal inhibitory reflexes during induction of anesthesia and intubation. Symax Duotab® protects against the peripheral muscarinic effects such as bradycardia and excessive secretions produced by halogenated hydrocarbons and cholinergic agents such as physostigmine, neostigmine, and pyridostigmine given to reverse the actions of curariform agents.

IN UROLOGY:

Symax Duotab® injection may also be used intravenously to improve radiologic visibility of the kidneys. It is also indicated along with morphine or other narcotics in symptomatic relief of biliary and renal colic.

How should I use Symax Duotab?

Use Symax Duotab spray as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Symax Duotab spray. Talk to your pharmacist if you have questions about this information.
• Symax Duotab spray is usually taken 30 to 60 minutes before a meal. Follow your doctor's instructions for taking Symax Duotab spray.
• The spray pump must be primed before you use the first dose of Symax Duotab spray. Remove the plastic cover and point the opening away from yourself and others. Press down firmly and quickly until a fine mist appears (at least 3 sprays).
• To use Symax Duotab spray, hold the container upright. Open your mouth and bring the container as close as possible. Press down firmly and close your mouth. If necessary, repeat as directed by your doctor.
• Do not swallow immediately after you use the spray. Do not spit or rinse your mouth for 5 to 10 minutes after you use Symax Duotab spray.
• If you have not used the spray pump for 2 days or more, reprime before using it. Point the opening away from yourself and others and spray 1 time to reprime.
• Wipe the spray tip with a clean tissue and replace the cover.
• Do not use this bottle for more than 30 sprays even if it looks like it still contains medicine. The pump may not deliver the correct amount of medicine after 30 sprays.
• Do not take extra doses or stop using Symax Duotab spray without first checking with your doctor.
• If you also take antacids, take Symax Duotab spray before meals and the antacid after meals, unless directed otherwise by your doctor.
• If you miss a dose of Symax Duotab spray, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Symax Duotab spray.

Uses of Symax Duotab in details

Symax Duotab is used to treat a variety of stomach/intestinal problems such as cramps and irritable bowel syndrome. It is also used to treat other conditions such as bladder and bowel control problems, cramping pain caused by kidney stones and gallstones, and Parkinson's disease. In addition, it is used to decrease side effects of certain medications (drugs used to treat myasthenia gravis) and insecticides.

This medication works by decreasing acid production in the stomach, slowing down the natural movements of the gut, and relaxing muscles in many organs (e.g., stomach, intestines, bladder, kidney, gallbladder). Symax Duotab also lessens the amount of certain body fluids (e.g., saliva, sweat). This medication belongs to a class of drugs known as anticholinergics/antispasmodics.

How to use Symax Duotab sublingual

Place this medication under the tongue and allow it to dissolve. This medication may also be swallowed whole or chewed. It may be taken with or without meals. Take it as prescribed by your doctor.

Dosage is based on your medical condition and response to therapy. Do not increase your dose or take it more often than prescribed without consulting your doctor. Adults and children 12 years and older should not take more than 1.5 milligrams in 24 hours. Children aged 2 to 12 years should not take more than 0.75 milligrams in 24 hours. Ask your doctor or pharmacist for more information.

Antacids lower the absorption of Symax Duotab. If you use antacids, take them after meals and take Symax Duotab before meals; or take antacids at least 1 hour after taking Symax Duotab.

Drink plenty of fluids while taking this medication unless your doctor directs you otherwise.

Inform your doctor if your condition persists or worsens.

Symax Duotab description

Symax Duotab is a chemical compound, a tropane alkaloid it is the levo-isomer to atropine. It is a secondary metabolite of some plants, particularly henbane (Hyoscamus niger.) Symax Duotab is used to provide symptomatic relief to various gastrointestinal disorders including spasms, peptic ulcers, irritable bowel syndrome, pancreatitis, colic and cystitis. It has also been used to relieve some heart problems, control some of the symptoms of Parkinson's disease, as well as for control of respiratory secretions in end of life care.

Symax Duotab dosage

Symax Duotab Dosage

Generic name: Symax Duotab SULFATE.125mg

Dosage form: tablet

See also:

• Symax Duotab-DT tablet
• Symax Duotab-FT Chewable Melt tablet
• Symax Duotab-SL tablet
• Symax Duotab-SR tablet

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual adult and adolescent dose: 1 to 2 tablets three or four times a day, thirty minutes to one hour before meals and at bedtime, the dosage being adjusted as needed and tolerated.

Note: Geriatric patients may be more sensitive to the effects of the usual adult dose.

Usual dose for children 6 to under 12 years of age: 1/2 to 1 tablet three or four times a day, thirty minutes to one hour before meals and at bedtime. Dosage should be individualized by physician according to patient’s needsand tolerance

Note: This product is not recommended for use in children under six years of age.

More about Symax Duotab (Symax Duotab)

• Side Effects
• During Pregnancy
• Dosage Information
• Drug Interactions
• Support Group
• En Espanol
• 1 Review - Add your own review/rating

Consumer resources

• Symax Duotab

• Other brands: Symax Duotab, Symax Duotab, Symax Duotab, Symax Duotab, More (15) »

Professional resources

• Symax Duotab (FDA)
• Symax Duotab Sulfate (AHFS Monograph)

Other formulations

• Symax Duotab SL
• Symax Duotab FT
• Symax Duotab SR
• More (1) »

Related treatment guides

• Anesthesia
• Crohn's Disease
• Endoscopy or Radiology Premedication
• Irritable Bowel Syndrome
• Urinary Incontinence

Symax Duotab interactions

See also:
What other drugs will affect Symax Duotab?

Additive adverse effects resulting from cholinergic blockade may occur when Symax Duotab® (Symax Duotab) is administered concomitantly with other antimuscarinics, amantadine, haloperidol, phenothiazines, monoamine oxidase (MAO) inhibitors, tricyclic antidepressants or some antihistamines.

Antacids may interfere with the absorption of Symax Duotab® (Symax Duotab). Administer Symax Duotab® (Symax Duotab) before meals; antacids after meals.

Symax Duotab side effects

See also:
What are the possible side effects of Symax Duotab?

Applies to Symax Duotab: oral conventional tablets and sublingual tablets, oral extended-release capsules and tablets, oral oral solution and elixir, oral orally disintegrating tablets, parenteral injection

Side effects include:

Most adverse effects are manifestations of pharmacologic effects at muscarinic-cholinergic receptors and usually are reversible when therapy is discontinued.

Severity and frequency of adverse effects are dose related and individual intolerance varies greatly; adverse effects occasionally may be obviated by a reduction in dosage but this also may eliminate potential therapeutic effects.

Adverse effects include dry mouth, urinary hesitancy and retention, blurred vision, tachycardia, palpitations, mydriasis, increased ocular tension, loss of taste, headache, nervousness, drowsiness, weakness, fatigue, dizziness, insomnia, nausea, vomiting, impotence, constipation, bloated feeling, abdominal pain, diarrhea, allergic reactions or drug idiosyncrasies, urticaria and other dermal manifestations, ataxia, speech disturbance, mental confusion and/or excitement (especially in geriatric patients), short-term memory loss, hallucinations, and decreased sweating.

Symax Duotab contraindications

See also:
What is the most important information I should know about Symax Duotab?

Do not take Symax Duotab if you are allergic to it, or if you have kidney disease, a bladder or intestinal obstruction, severe ulcerative colitis, toxic megacolon, glaucoma, or myasthenia gravis.

Before taking Symax Duotab, tell your doctor if you have heart disease, congestive heart failure, a heart rhythm disorder, high blood pressure, overactive thyroid, or hiatal hernia with gastroesophageal reflux disease.

Avoid taking antacids at the same time you take Symax Duotab. Antacids can make it harder for your body to absorb Symax Duotab. If you use an antacid, take it after you have taken Symax Duotab and eaten a meal.

Symax Duotab may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Drinking alcohol can increase drowsiness and dizziness while you are taking Symax Duotab.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Symax Duotab can decrease sweating and you may be more prone to heat stroke.

Active ingredient matches for Symax Duotab:

Hyoscyamine

375mg/HYOSCYAMINE SULFATE 0

Hyoscyamine Long-Acting Tablets

References

1. PubChem. "hyoscyamine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
2. DrugBank. "hyoscyamine". http://www.drugbank.ca/drugs/DB00424 (accessed September 17, 2018).
3. MeSH. "Parasympatholytics". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

Reviews

User reports

Consumer reviews

Information checked by Dr. Sachin Kumar, MD Pharmacology