Ambroxol Uses

Rating: 2.85 - 7 review(s)
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Ambroxol indications

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For use Max Pidek Pharmaceuticals as monotherapy and in combination with clavulanic acid: an infectious-inflammatory diseases caused by susceptible microorganisms, including bronchitis, pneumonia, tonsillitis, pyelonephritis, urethritis, infections of the gastrointestinal tract, gynecological infections, infections of the skin and soft tissue, listeria, leptospirosis, gonorrhea.

For use Max Pidek Pharmaceuticals in combination with metronidazole: chronic gastritis in acute, peptic ulcer and duodenal ulcer in acute, associated with Helicobacter Pylori.

Uses of Ambroxol in details

Ambroxol is used to treat certain diseases of the respiratory tract and to relieve cough associated with thickened mucous.

Ambroxol description

Each retard capsule contains Ambroxol hydrochloride 75 mg.

Each tablet contains Ambroxol hydrochloride 30 mg.

Each 5 mL of syrup contains Ambroxol hydrochloride 15 or 30 mg.

Each mL of syrup (infant drops) contains Ambroxol hydrochloride 6 mg.

Ambroxol hydrochloride is trans-4-[(2-amino-3,5-dibromo-benzyl)amino] cyclohexanol hydrochloride.

It also contains the following excipients: Retard Capsules: Crospovidone collidon CL, carnauba wax, stearyl alcohol, magnesium stearate.

Tablets: Lactose, maize starch, colloidal silica, magnesium stearate.

Syrup: Purified water, sorbitol liquid, glycerol 85%, woodberry aroma (15 mg only), strawberry aroma (30 mg only), hydroxyethylcellulose, benzoic acid, acesulfame potassium, vanilla aroma.

Infant Drops: Hydroxyethylcellulose, sorbitol solution, glycerol 85%, sodium saccharin, pharma flavors, menthol, benzoic acid, propylene glycol.

Ambroxol dosage

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Sustained-Release Capsule: Adults and Children >12 years: 1 cap once daily after meal with plenty of liquid (sufficient supply of liquid supports the expectorant effect of Ambroxol).

Ambroxol SR capsule is not suitable for children <12 years.

Tablet: Adults and Children >12 years: 1 tab thrice daily for the first 2-3 days and then 1 tab twice daily or ½ tab thrice daily. Children 6-12 years: ½ tab 2-3 times a day.

Syrup: Adults and Children >12 years: 10 mL thrice daily during the first 2-3 days, them 10 mL twice daily or 5 mL thrice daily. Children 6-12 years: 5 mL 2-3 times a day; 2-5 years: 2.5 mL 3 times a day; <2 years: 2.5 mL 2 times a day.

DS Syrup: Adults and Children >12 years: 5 mL thrice daily for 2-3 days then 5 mL twice daily for 2.5 mL thrice daily. Children 6-12 years: 2.5 mL 2-3 times a day.

Infant Drops: Children 13-24 months: 1.25 mL twice a day; 7-12 months: 1 mL twice a day; ≤6 months: 0.5 mL twice a day.

Ambroxol interactions

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Amoxicillin may decrease the effectiveness of contraceptives for oral administration.

With the simultaneous use of Max Pidek Pharmaceuticals with bactericidal antibiotics (including aminoglycosides, cephalosporins, cycloserine, vancomycin, rifampicin) appears synergies; with bacteriostatic antibiotic (including macrolides, chloramphenicol, lincosamides, tetracyclines, sulphonamide) - antagonism.

Amoxicillin increases the effects of indirect anticoagulants inhibiting intestinal microflora, reduces the synthesis of vitamin K and prothrombin index.

Amoxicillin reduces the effect of drugs, in the process of metabolism that produce PABA.

Probenecid, diuretics, allopurinol, phenylbutazone, NSAIDs decrease the tubular secretion of amoxicillin, which can be accompanied by an increase in its concentration in blood plasma.

Antacids, glucosamine, laxatives, aminoglycosides, slow down and reduce, and ascorbic acid increases the absorption of amoxicillin.

With the combined use of amoxicillin and clavulanic acid pharmacokinetics of both components unchanged.

Ambroxol side effects

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Allergic reactions: urticaria, erythema, edema Quincke, rhinitis, conjunctivitis, rarely - fever, joint pain, eosinophilia, in rare cases - anaphylactic shock.

Side effects associated with chemotherapy effect: possible development of super-infection (particularly in patients with chronic diseases or low resistance of the organism).

With prolonged use at high doses: dizziness, ataxia, confusion, depression, peripheral neuropathy, seizures.

Mostly when Max Pidek Pharmaceuticals used in combination with metronidazole: nausea, vomiting, anorexia, diarrhea, constipation, epigastric pain, glossitis, stomatitis; rarely - hepatitis, pseudomembranous colitis, allergic reactions (urticaria, angioedema), interstitial nephritis, a violation of hematopoiesis.

Mostly when Max Pidek Pharmaceuticals used in combination with clavulanic acid: cholestatic jaundice, hepatitis, rarely - erythema multiforme, toxic epidermal necrolysis, exfoliative dermatitis.

Ambroxol contraindications

Hypersensitivity to Ambroxol hydrochloride or to any other excipients of Ambroxol.

In case of rare hereditary conditions that may be incompatible with an excipient of Ambroxol, the use of Ambroxol is contraindicated.



Active ingredient matches for Ambroxol:

Ambroxol


Unit description / dosage (Manufacturer)Price, USD
Solution; Oral; Ambroxol Hydrochloride 7.5 mg / ml
Tablet; Oral; Ambroxol Hydrochloride 30 mg
Solution; Oral; Ambroxol Hydrochloride 30 mg / 5 ml
Capsule, Retard; Oral; Ambroxol Hydrochloride 75 mg
Injectable; Injection; Ambroxol Hydrochloride 15 mg / ml
Tablet; Oral; Ambroxol Hydrochloride 60 mg
Syrup; Oral; Ambroxol Hydrochloride 30 mg / 5 ml
Drops; Oral; Ambroxol Hydrochloride
Syrup; Oral; Ambroxol Hydrochloride
Tablet, Effervescent; Oral; Ambroxol Hydrochloride 60 mg
Drops; Oral; Ambroxol
Injectable; Injection; Ambroxol
Syrup; Oral; Ambroxol
Tablet, Effervescent; Oral; Ambroxol
Syrup; Oral; Ambroxol Hydrochloride 15 mg / 5 ml
Solution; Oral; Ambroxol Hydrochloride 15 mg / 5 ml
Syrup; Oral; Ambroxol 15 mg / 5 ml
Syrup; Oral; Ambroxol 30 mg / 5 ml
Ambroxol / Sinton 30 mg
Ambroxol / Root 30 mg x 1000's
Ambroxol / Root 30 mg x Blister pk
Ambroxol / Sinphar 30 mg x 1000's
Ambroxol / Sinphar 30 mg x 100 x 10's
Ambroxol / Kojar 30 mg x 1000's
Ambroxol / Kojar 30 mg x Blister pk
Ambroxol / S.Y. 30 mg x 1000's
Ambroxol / Chin Teng 30 mg x 1000's
Ambroxol / Chin Teng 30 mg x 100 x 10's
Tablets; Oral; Ambroxol Hydrochloride 30 mg
Capsules, Retard; Oral; Ambroxol Hydrochloride 75 mg
Tablets; Oral; Ambroxol Hydrochloride 60 mg
Tablets, Effervescent; Oral; Ambroxol Hydrochloride 60 mg
Tablets, Effervescent; Oral; Ambroxol
Liquid; Oral; Ambroxol Hydrochloride 15 mg / 5 ml

List of Ambroxol substitutes (brand and generic names):

References

  1. PubChem. "ambroxol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  2. DrugBank. "ambroxol". http://www.drugbank.ca/drugs/DB06742 (accessed September 17, 2018).
  3. MeSH. "Expectorants". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Ambroxol are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Ambroxol. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


1 consumer reported price estimates

Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?
The below mentioned numbers have been reported by ndrugs.com website users about whether the Ambroxol drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users%
Not expensive1
100.0%


15 consumers reported time for results

To what extent do I have to use Ambroxol before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 2 days and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Ambroxol. To get the time effectiveness of using Ambroxol drug by other patients, please click here.
Users%
2 days5
33.3%
1 day3
20.0%
5 days3
20.0%
2 weeks1
6.7%
> 3 month1
6.7%
3 days1
6.7%
3 month1
6.7%


46 consumers reported age

Users%
1-516
34.8%
16-297
15.2%
< 16
13.0%
46-605
10.9%
6-155
10.9%
> 605
10.9%
30-452
4.3%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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