Broomhexine HCl RXT indications
Broomhexine HCl RXT hydrochloride SYRUP indicated for cough associated with wheeziness (bronchospasm) and tenacious phlegm (sputum).
Uses of Broomhexine HCl RXT in details
Broomhexine HCl RXT is used to treat breathing difficulties caused by excessive mucus secretions in the air passages associated with respiratory tract infections.
Broomhexine HCl RXT description
Each tablet also contains lactose, maize or potato starch, gelatine and magnesium stearate as excipients.
The oral/inhalation solution also contains tartaric acid and methyl parahydroxybenzoate as excipients.
The syrup also contains tartaric acid, benzoic acid, sodium carboxymethylcellulose, glycerol, sorbitol solution, pharma flavor and ethanol as excipients.
Each capsule also contains lactose, cornstarch and magnesium stearate as excipients.
Broomhexine HCl RXT HCl is N-cyclohexyl-N-methyl-(2-amino-3,5-dibromobenzyl)amine hydrochloride.
Broomhexine HCl RXT dosage
Unless otherwise prescribed, the following doses are recommended:
Tablet: Adults and Children >12 years: 8 mg (1 tab) thrice daily; 6-12 years: 4 mg (½ tab) thrice daily; 2-6 years: 4 mg (½ tab) twice daily.
Oral Solution:
Adults and Children >12 years: 4 mL thrice daily; 6-12 years: 2 mL thrice daily; 2-6 years: 20 drops thrice daily; <2 years: 10 drops thrice daily.Inhalation Solution (with aerosol apparatus): It is generally recommended to warm inhalation solution to body temperature before inhalation. Patients with bronchial asthma may be advised to commencing inhalation after they have taken their regular bronchospasmolytic therapy.
Adults: 4 mL. Children >12 years: 2 mL; 6-12 years: 1 mL; 2-6 years: 10 drops; <2 years: 5 drops. All doses to be taken twice daily.
The solution may be diluted 1:1 in physiological saline solution. In order to avoid precipitation, the solution should be inhaled immediately after mixing. The combined administration of inhalation and oral application intensifies the effect, and is especially suited for the commencement of treatment in cases where the full effect is to be reached quickly.
Syrup: Adults and Children >12 years: 5 ml (1 tsp) thrice daily.
At commencement of treatment, it may be necessary to increase the total daily dose up to 48 mg in adults.
The syrup is sugar-free and therefore suitable for diabetics and small children.
Ampoule: Severe cases, before and after surgical intervention: 1 amp SC, IM or IV (duration of injection: 2-3 min) 2-3 times daily.
Capsule: Adults: 1 cap 3 times daily.
It is recommended for the initial phase of treatment usually lasting not more than a week.
Patients being treated with Broomhexine HCl RXT should be notified of an expected increase in the flow of secretions.
Broomhexine HCl RXT interactions
A reduction in dose of cardiac glycosides (e.g. digitalis) and quinidine might become necessary in patients suffering from congestive cardiac failure because of the positive inotropic effect of orciprenaline sulphate.
Broomhexine HCl RXT hydrochloride SYRUP should not be administered concomitantly with beta-blocking agents, due to orciprenaline’s reversal of anti-hypertensive action.
The concomitant use of other sympathomimetic agents should be carefully controlled to avoid potentiation of effects.
Broomhexine HCl RXT side effects
Broomhexine HCl RXT’s pharmacological action may lead to gastric irritation. A transient rise in serum aminotransferase values have been reported due to Broomhexine HCl RXT.
Orciprenaline sulphate, as a sympathomimetic agent, may precipitate a wide range of adverse effects. Side-effects include fear; anxiety, restlessness, tremor, insomnia, confusion, irritability, weakness and psychotic states. Appetite may be reduced and nausea and vomiting may occur. A rise in blood pressure which may produce cerebral haemorrhage and pulmonary oedema, tachycardia and cardiac arrhythmias, anginal pain, palpitations, and cardiac arrest. Hypotension with dizziness and fainting and flushing may occur. Other effects that may occur include difficulty in micturition and urinary retention; dyspnoea; weakness; headache; disturbances of glucose metabolism; sweating and hypersalivation. Muscle cramps or twitching or unpleasant taste may occur.
Broomhexine HCl RXT contraindications
Broomhexine HCl RXT hydrochloride SYRUP is contra-indicated in patients with known hypersensitivity to sympathomimetic amines or any of the other ingredients; hypertrophic obstructive cardiomyopathy; and tachyarrhythmia.
Sympathomimetics, such as orciprenaline sulphate, may interact with monoamine oxidase inhibitors (MAOI), and therefore Broomhexine HCl RXT hydrochloride SYRUP should not be given to patients receiving such treatment or within 14 days of MAOI treatment termination.
Safety in pregnancy and lactation has not been established.
Active ingredient matches for Broomhexine HCl RXT:
Bromhexine in Netherlands.
List of Broomhexine HCl RXT substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Broomhexine Hydrochloride 8mg (Netherlands) | |
| Broomhexinehydrochloride Samenwerkende Apothekers (Netherlands) | |
| Bropavol (Chile) | |
| Bropect | |
| Bropect 100 ml Expectorant (The Pharmed Research Lab Pvt Ltd) | $ 0.02 |
| Bropect 50 ml Expectorant (The Pharmed Research Lab Pvt Ltd) | $ 0.03 |
| Bropect-T | |
| Bropect-T 50 ml Expectorant (The Pharmed Research Lab Pvt Ltd) | $ 0.03 |
| Bropect-T 100 ml Expectorant (The Pharmed Research Lab Pvt Ltd) | $ 0.03 |
| Broplas | |
| Broplas 100 ml Expectorant (Plasmid Health Care Pvt. Ltd.) | $ 0.02 |
| Bros Expectorant | |
| Bros Expectorant 60 ml Expectorant (Bevit Pharmaceuticals Ltd.) | $ 0.02 |
| Brosal-G | |
| Brosal-G 60 ml Expectorant (Acron Pharmaceuticals) | $ 0.02 |
| Broson (India) | |
| Broson 100 ml Syrup (Agron Remedies Pvt Ltd) | $ 0.01 |
| BROSON syr 100ml (Agron Remedies Pvt Ltd) | $ 0.18 |
| Brost-G | |
| Brost-G 100 ml Expectorant (Osho Laboratories (P) Ltd.) | $ 0.02 |
| Brotex-G | |
| Brotex-G 100 ml Syrup (Antiseptic Pharmaceuticals) | $ 0.05 |
| Brotex-G 50 ml Syrup (Antiseptic Pharmaceuticals) | $ 0.03 |
| Brovol (Thailand) | |
| Brovol 4 mg/5 mL x 60 mL | |
| Brovol 4 mg/5 mL x 1 gal | |
| Browin Jun (India) | |
| Browin Jun Bromhexine 2 mg, Terbutaline1.25 mg, Guaifenesin 25 mg. EXP / 100ml | $ 0.37 |
| 100ml | $ 0.37 |
| Browin Junior | |
| Browin Junior 100 ml Expectorant (Wintech Pharmaceuticals) | $ 0.02 |
| Broxil B | |
| Broxil B 100 ml Syrup (Aries Drugs Pvt. Ltd.) | $ 0.03 |
| Broxine (Bangladesh) | |
| Broxine 8+2 Tablet (Healthy Life Pharma Pvt. Ltd.) | $ 0.00 |
| Broxine 100 ml Syrup (Healthy Life Pharma Pvt. Ltd.) | $ 0.02 |
| BROXINE SYRUP 1 bottle / 100 ML syrup each (Healthy Life Pharma Pvt. Ltd.) | $ 0.40 |
| BROXINE TABLET 1 strip / 10 tablets each (Healthy Life Pharma Pvt. Ltd.) | $ 0.30 |
| Broxine NA Syrup (Healthy Life Pharma Pvt. Ltd.) | $ 0.45 |
| Broxolvon (Netherlands) | |
| Broxy | |
| Broxy 250+4 Tablet (Pharmindia) | $ 0.05 |
| Broxy 500 mg Injection (Pharmindia) | $ 0.43 |
| Broxy 250 mg Injection (Pharmindia) | $ 0.55 |
| Brucof Plus | |
| Brucof Plus 100 ml Syrup (Brussels Laboratories Pvt. Ltd.) | $ 0.02 |
| Butabrom Ds | |
| Butabrom Ds 200+8+5 Tablet (Rekvina Pharmaceuticals) | $ 0.04 |
| Butabrom DS 100 mg/4 mg/2.5 mg Tablet (Rekvina Pharmaceuticals) | $ 0.04 |
| Buzetin (Thailand) | |
| Buzetin | |
| Buzetin 8 mg x 1000's | |
| C-Cold (India) | |
| C-Cold Bromhexine hydrochloride 2 mg, Salbutamol sulphate 1 mg, Guaiphenesin 50 mg, Menthol0.5 mg/5 mL. SYR / 100ml (Corona) | |
| 100ml (Corona) | |
| C-Cold 2 Blister x 6 Tablet (Corona) | |
| C-COLD syr 100ml (Corona) | |
| C1000 Broomhexine (Netherlands) | |
| Cadikof BR | |
| Cadikof BR 100 ml Syrup (Alcure Pharmaceutical Laboratories (India)) | $ 0.05 |
| Cafol | |
| Cafol 100 ml Syrup (Greenco Biologicals Pvt Ltd) | $ 0.02 |
See 1877 substitutes for Broomhexine HCl RXT | |
References
- PubChem. "bromhexine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "Bromhexine". http://www.drugbank.ca/drugs/DB09019 (accessed September 17, 2018).
- MeSH. "Expectorants". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Broomhexine HCl RXT are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Broomhexine HCl RXT. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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| Users | % | ||
|---|---|---|---|
| 46-60 | 1 | 100.0% | |
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Information checked by Dr. Sachin Kumar, MD Pharmacology
