Brotex-G indications
Brotex-G hydrochloride SYRUP indicated for cough associated with wheeziness (bronchospasm) and tenacious phlegm (sputum).
Uses of Brotex-G in details
Brotex-G is used to treat breathing difficulties caused by excessive mucus secretions in the air passages associated with respiratory tract infections.
Brotex-G description
Each tablet also contains lactose, maize or potato starch, gelatine and magnesium stearate as excipients.
The oral/inhalation solution also contains tartaric acid and methyl parahydroxybenzoate as excipients.
The syrup also contains tartaric acid, benzoic acid, sodium carboxymethylcellulose, glycerol, sorbitol solution, pharma flavor and ethanol as excipients.
Each capsule also contains lactose, cornstarch and magnesium stearate as excipients.
Brotex-G HCl is N-cyclohexyl-N-methyl-(2-amino-3,5-dibromobenzyl)amine hydrochloride.
Brotex-G dosage
Unless otherwise prescribed, the following doses are recommended:
Tablet: Adults and Children >12 years: 8 mg (1 tab) thrice daily; 6-12 years: 4 mg (½ tab) thrice daily; 2-6 years: 4 mg (½ tab) twice daily.
Oral Solution:
Adults and Children >12 years: 4 mL thrice daily; 6-12 years: 2 mL thrice daily; 2-6 years: 20 drops thrice daily; <2 years: 10 drops thrice daily.Inhalation Solution (with aerosol apparatus): It is generally recommended to warm inhalation solution to body temperature before inhalation. Patients with bronchial asthma may be advised to commencing inhalation after they have taken their regular bronchospasmolytic therapy.
Adults: 4 mL. Children >12 years: 2 mL; 6-12 years: 1 mL; 2-6 years: 10 drops; <2 years: 5 drops. All doses to be taken twice daily.
The solution may be diluted 1:1 in physiological saline solution. In order to avoid precipitation, the solution should be inhaled immediately after mixing. The combined administration of inhalation and oral application intensifies the effect, and is especially suited for the commencement of treatment in cases where the full effect is to be reached quickly.
Syrup: Adults and Children >12 years: 5 ml (1 tsp) thrice daily.
At commencement of treatment, it may be necessary to increase the total daily dose up to 48 mg in adults.
The syrup is sugar-free and therefore suitable for diabetics and small children.
Ampoule: Severe cases, before and after surgical intervention: 1 amp SC, IM or IV (duration of injection: 2-3 min) 2-3 times daily.
Capsule: Adults: 1 cap 3 times daily.
It is recommended for the initial phase of treatment usually lasting not more than a week.
Patients being treated with Brotex-G should be notified of an expected increase in the flow of secretions.
Brotex-G interactions
A reduction in dose of cardiac glycosides (e.g. digitalis) and quinidine might become necessary in patients suffering from congestive cardiac failure because of the positive inotropic effect of orciprenaline sulphate.
Brotex-G hydrochloride SYRUP should not be administered concomitantly with beta-blocking agents, due to orciprenaline’s reversal of anti-hypertensive action.
The concomitant use of other sympathomimetic agents should be carefully controlled to avoid potentiation of effects.
Brotex-G side effects
Brotex-G’s pharmacological action may lead to gastric irritation. A transient rise in serum aminotransferase values have been reported due to Brotex-G.
Orciprenaline sulphate, as a sympathomimetic agent, may precipitate a wide range of adverse effects. Side-effects include fear; anxiety, restlessness, tremor, insomnia, confusion, irritability, weakness and psychotic states. Appetite may be reduced and nausea and vomiting may occur. A rise in blood pressure which may produce cerebral haemorrhage and pulmonary oedema, tachycardia and cardiac arrhythmias, anginal pain, palpitations, and cardiac arrest. Hypotension with dizziness and fainting and flushing may occur. Other effects that may occur include difficulty in micturition and urinary retention; dyspnoea; weakness; headache; disturbances of glucose metabolism; sweating and hypersalivation. Muscle cramps or twitching or unpleasant taste may occur.
Brotex-G contraindications
Brotex-G hydrochloride SYRUP is contra-indicated in patients with known hypersensitivity to sympathomimetic amines or any of the other ingredients; hypertrophic obstructive cardiomyopathy; and tachyarrhythmia.
Sympathomimetics, such as orciprenaline sulphate, may interact with monoamine oxidase inhibitors (MAOI), and therefore Brotex-G hydrochloride SYRUP should not be given to patients receiving such treatment or within 14 days of MAOI treatment termination.
Safety in pregnancy and lactation has not been established.
Active ingredient matches for Brotex-G:
| Unit description / dosage (Manufacturer) | Price, USD |
| Brotex-G 100 ml Syrup | $ 0.05 |
| Brotex-G 50 ml Syrup | $ 0.03 |
List of Brotex-G substitutes (brand and generic names): | |
| Brost-G | |
| Brost-G 100 ml Expectorant (Osho Laboratories (P) Ltd.) | $ 0.02 |
| Brovol (Thailand) | |
| Brovol 4 mg/5 mL x 60 mL | |
| Brovol 4 mg/5 mL x 1 gal | |
| Browin Jun (India) | |
| Browin Jun Bromhexine 2 mg, Terbutaline1.25 mg, Guaifenesin 25 mg. EXP / 100ml | $ 0.37 |
| 100ml | $ 0.37 |
| Browin Junior | |
| Browin Junior 100 ml Expectorant (Wintech Pharmaceuticals) | $ 0.02 |
| Broxil B | |
| Broxil B 100 ml Syrup (Aries Drugs Pvt. Ltd.) | $ 0.03 |
| Broxine (Bangladesh) | |
| Broxine 8+2 Tablet (Healthy Life Pharma Pvt. Ltd.) | $ 0.00 |
| Broxine 100 ml Syrup (Healthy Life Pharma Pvt. Ltd.) | $ 0.02 |
| BROXINE SYRUP 1 bottle / 100 ML syrup each (Healthy Life Pharma Pvt. Ltd.) | $ 0.40 |
| BROXINE TABLET 1 strip / 10 tablets each (Healthy Life Pharma Pvt. Ltd.) | $ 0.30 |
| Broxine NA Syrup (Healthy Life Pharma Pvt. Ltd.) | $ 0.45 |
| Broxolvon (Netherlands) | |
| Broxy | |
| Broxy 250+4 Tablet (Pharmindia) | $ 0.05 |
| Broxy 500 mg Injection (Pharmindia) | $ 0.43 |
| Broxy 250 mg Injection (Pharmindia) | $ 0.55 |
| Brucof Plus | |
| Brucof Plus 100 ml Syrup (Brussels Laboratories Pvt. Ltd.) | $ 0.02 |
| Butabrom Ds | |
| Butabrom Ds 200+8+5 Tablet (Rekvina Pharmaceuticals) | $ 0.04 |
| Butabrom DS 100 mg/4 mg/2.5 mg Tablet (Rekvina Pharmaceuticals) | $ 0.04 |
| Buzetin (Thailand) | |
| Buzetin | |
| Buzetin 8 mg x 1000's | |
| C-Cold (India) | |
| C-Cold Bromhexine hydrochloride 2 mg, Salbutamol sulphate 1 mg, Guaiphenesin 50 mg, Menthol0.5 mg/5 mL. SYR / 100ml (Corona) | |
| 100ml (Corona) | |
| C-Cold 2 Blister x 6 Tablet (Corona) | |
| C-COLD syr 100ml (Corona) | |
| C1000 Broomhexine (Netherlands) | |
| Cadikof BR | |
| Cadikof BR 100 ml Syrup (Alcure Pharmaceutical Laboratories (India)) | $ 0.05 |
| Cafol | |
| Cafol 100 ml Syrup (Greenco Biologicals Pvt Ltd) | $ 0.02 |
| CAFOL SYRUP 1 bottle / 100 ML syrup each (Greenco Biologicals Pvt Ltd) | $ 0.51 |
| Cafol Syrup (Greenco Biologicals Pvt Ltd) | $ 0.51 |
| Camoxy Plus | |
| Camoxy Plus 250+8 Capsule (Mediwin Pharmaceuticals) | $ 0.04 |
| Capex-Bron Exp (India) | |
| Capex-Bron Exp Terbutaline sulphate 1.5 mg, Bromhexine hydrochloride 4 mg, Guaiphenesin 50 mg/5 mL. EXP / 120ml (Seagull) | $ 0.36 |
| 120ml (Seagull) | $ 0.36 |
| CAPEX-BRON EXP syr 120ml (Seagull) | $ 0.36 |
| Catarrosine (Argentina) | |
| Celar | |
| Celar 8+25 Tablet (Chemo Drugs) | $ 0.01 |
| Cep Bro | |
| Cep Bro 4+250 Capsule (Cadila Pharmaceuticals Ltd.) | $ 0.07 |
| Cetariv-B | |
| Cetariv-B 100 ml Syrup (East African (I) Remedies Pvt Ltd) | $ 0.02 |
| Chemidrex-E | |
| Chemidrex-E 100 ml Syrup (Times Drugs & Pharmaceuticals (P) Ltd.) | $ 0.02 |
| Cherifon | |
| Cherifon 100 ml Syrup (Roman Lifesciences Pvt.Ltd) | $ 0.03 |
| Cheritop M | |
| Cheritop M 100 ml Syrup (Zentis Drugs Pvt Ltd) | $ 0.03 |
| Cheritop-M (India) | |
| Cheritop-M Terbutaline sulphate 1.25 mg, Bromhexine hydrochloride 2 mg, Guaiphenesin 50 mg. SYR / 100ml (Zentis) | $ 0.54 |
See 1876 substitutes for Brotex-G | |
References
- PubChem. "bromhexine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "Bromhexine". http://www.drugbank.ca/drugs/DB09019 (accessed September 17, 2018).
- MeSH. "Expectorants". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Brotex-G are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Brotex-G. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
1 consumer reported useful
Was the Brotex-G drug useful in terms of decreasing the symptom or the disease?According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
| Users | % | ||
|---|---|---|---|
| Useful | 1 | 100.0% | |
Consumer reported price estimates
No survey data has been collected yet2 consumers reported time for results
To what extent do I have to use Brotex-G before I begin to see changes in my health conditions?As part of the reports released by ndrugs.com website users, it takes 1 month and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Brotex-G. To get the time effectiveness of using Brotex-G drug by other patients, please click here.
| Users | % | ||
|---|---|---|---|
| 1 month | 1 | 50.0% | |
| 3 month | 1 | 50.0% | |
5 consumers reported age
| Users | % | ||
|---|---|---|---|
| 30-45 | 3 | 60.0% | |
| > 60 | 1 | 20.0% | |
| 46-60 | 1 | 20.0% | |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
