What is Brophemin?
Brophemin is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Brophemin is used to treat runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.
Brophemin may also be used for purposes not listed in this medication guide.
Brophemin indications
allergic rhinitis, hypersensitivity reactions
How should I use Brophemin?
Use Brophemin as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Brophemin may be taken with food if it upsets your stomach.
- Shake well before using.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- If you miss a dose of Brophemin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Brophemin.
Uses of Brophemin in details
Brophemin is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, watery eyes, itchy eyes/nose/throat/skin, cough, runny nose, and sneezing.
This medication works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. By blocking another natural substance made by your body (acetylcholine), it helps dry up some body fluids to relieve symptoms such as watery eyes and runny nose.
Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Ask your doctor or pharmacist for more details about using your product safely.
These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Do not use this product to make a child sleepy. Do not give other cough-and-cold medication that might contain the same or similar ingredients. Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).
How to use Brophemin
Take the tablet, capsule, or liquid form by mouth with or without food or as directed by your doctor. This medication may be taken with food or milk if stomach upset occurs.
If you are taking extended-release capsules, swallow them whole. Do not crush or chew extended-release capsules or tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.
If you are using chewable tablets, chew the tablet thoroughly before swallowing.
If you are using the liquid form, use a medication measuring device to carefully measure the prescribed dose. Do not use a household spoon. If your liquid form is a suspension, shake the bottle well before each dose.
Your dosage is based on your age, medical condition, and response to therapy. Do not increase your dose or take this medication more often without your doctor's approval. Take this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time(s) each day.
Inform your doctor if your condition persists or worsens.
Brophemin description
Brophemin maleate is an antihistamine used to treat allergic conditions such as hay fever or urticaria.
Brophemin dosage
Brophemin Dosage
Applies to the following strength(s): 2 mg/5 mL; 12 mg; 8 mg; 4 mg; 6 mg; 8 mg/5 mL; 10 mg/mL; 11 mg; 10 mg/5 mL; 12 mg/5 mL; 4 mg/5 mL; 1 mg/mL
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Usual Adult Dose for:
- Cold Symptoms
- Allergic Rhinitis
- Urticaria
- Allergic Reaction
Usual Pediatric Dose for:
- Allergic Rhinitis
- Cold Symptoms
- Urticaria
- Allergic Reaction
Additional dosage information:
- Renal Dose Adjustments
- Liver Dose Adjustments
- Precautions
- Dialysis
Usual Adult Dose for Cold Symptoms
Immediate Release: 4 mg to 8 mg orally every 6 hours as needed. The duration of action varies from patient to patient. Many patients will require dosing only twice daily.
Extended Release: 6 mg to 12 mg extended release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
Maximum oral dose 24 mg/day.
Usual Adult Dose for Allergic Rhinitis
Immediate Release: 4 mg to 8 mg orally every 6 hours as needed. The duration of action varies from patient to patient. Many patients will require dosing only twice daily.
Extended Release: 6 mg to 12 mg extended release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
Maximum oral dose 24 mg/day.
Usual Adult Dose for Urticaria
Immediate Release: 4 mg to 8 mg orally every 6 hours as needed. The duration of action varies from patient to patient. Many patients will require dosing only twice daily.
Extended Release: 6 mg to 12 mg extended release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
Maximum oral dose 24 mg/day.
Usual Adult Dose for Allergic Reaction
Immediate Release: 4 mg to 8 mg orally every 6 hours as needed. The duration of action varies from patient to patient. Many patients will require dosing only twice daily.
Extended Release: 6 mg to mg 12 mg extended release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
Maximum oral dose 24 mg/day.
IV, IM, subcutaneous: 5 mg to 20 mg every 6 to 12 hours. Duration of action is 3 to 12 hours.
Maximum parenteral dose 40 mg/day.
Usual Pediatric Dose for Allergic Rhinitis
< 6 years:
Immediate Release:
0.125 mg/kg/dose orally every 6 hours. Maximum dose: 6 mg to 8 mg/day.
2 to 6 years:
Extended Release suspension:
2 mg orally twice daily, not to exceed 2 doses in 24 hours.
6 to 12 years:
Immediate Release:
2 mg to 4 mg orally every 6 to 8 hours. Maximum dose 12 to 16 mg/day.
Extended Release suspension:
4 mg orally twice daily, not to exceed 2 doses in 24 hours.
> 12 years:
Immediate Release:
4 mg to 8 mg orally every 6 hours as needed. The duration of action varies from patient to patient. Many patients will require dosing only twice daily.
Extended Release:
6 mg to 12 mg sustained release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
Maximum oral dose 24 mg/day.
Usual Pediatric Dose for Cold Symptoms
< 6 years:
Immediate Release:
0.125 mg/kg/dose orally every 6 hours. Maximum dose: 6 mg to 8 mg/day.
2 to 6 years:
Extended Release suspension:
2 mg orally twice daily, not to exceed 2 doses in 24 hours.
6 to 12 years:
Immediate Release:
2 mg to 4 mg orally every 6 to 8 hours. Maximum dose 12 to 16 mg/day.
Extended Release suspension:
4 mg orally twice daily, not to exceed 2 doses in 24 hours.
> 12 years:
Immediate Release:
4 mg to 8 mg orally every 6 hours as needed. The duration of action varies from patient to patient. Many patients will require dosing only twice daily.
Extended Release:
6 mg to 12 mg sustained release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
Maximum oral dose 24 mg/day.
Usual Pediatric Dose for Urticaria
< 6 years:
Immediate Release:
0.125 mg/kg/dose orally every 6 hours. Maximum dose: 6 mg to 8 mg/day.
2 to 6 years:
Extended Release suspension:
2 mg orally twice daily, not to exceed 2 doses in 24 hours.
6 to 12 years:
Immediate Release:
2 mg to 4 mg orally every 6 to 8 hours. Maximum dose 12 to 16 mg/day.
Extended Release suspension:
4 mg orally twice daily, not to exceed 2 doses in 24 hours.
> 12 years:
Immediate Release:
4 mg to 8 mg orally every 6 hours as needed. The duration of action varies from patient to patient. Many patients will require dosing only twice daily.
Extended Release:
6 mg to 12 mg sustained release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
Maximum oral dose 24 mg/day.
Usual Pediatric Dose for Allergic Reaction
< 6 years:
Immediate Release:
0.125 mg/kg/dose orally every 6 hours. Maximum dose: 6 mg to 8 mg/day.
2 to 6 yrs:
Extended Release Suspension:
2.5 mg extended release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
6 to 12 years:
Immediate Release:
2 mg to 4 mg orally every 6 to 8 hours. Maximum dose 12 to 16 mg/day.
Extended Release Suspension:
5 mg extended release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
> 12 years:
Immediate Release:
4 mg orally every 6 hours as needed. The duration of action varies from patient to patient. Many patients will require dosing only twice daily.
Extended Release:
6 mg to 12 mg extended release orally twice daily as needed. The duration of action varies from patient to patient. Many patients will require dosing only once a day, preferably at bedtime to avoid drowsiness.
Maximum oral dose 24 mg/day.
IM, IV, subcutaneous :
< 12 years:
0.5 mg/kg/day divided every 6 to 8 hours.
> 12 years:
5 mg to 20 mg every 6 to 12 hours. Duration of action is 3 to 12 hours.
Maximum parenteral dose 40 mg/day.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
Brophemin should be used with caution in patients with asthma, heart disease, hypertension or thyroid disease.
Dialysis
Data not available
More about Brophemin
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- En Espanol
- 7 Reviews - Add your own review/rating
Consumer resources
- Brophemin
- Brophemin 24-hour sustained-release capsules
- Brophemin chewable tablets
- Brophemin liquid
- Brophemin
- Brophemin
- Other brands: Brovex, Bromax, Siltane, Lodrane 24, More (7) »
Professional resources
- Brophemin Drops (FDA)
- Brophemin (Wolters Kluwer)
Related treatment guides
- Allergic Reactions
- Allergic Rhinitis
- Cold Symptoms
- Urticaria
Brophemin interactions
See also:
What other drugs will affect Brophemin?
Brophemin can interact with alcohol or other CNS depressants (may potentiate the CNS depressant effects of either these medications or antihistamines), anticholinergics or other medications with anticholinergic activity (anticholinergic effects may be potentiated when these medications are used concurrently with antihistamines), and monoamine oxidase (MAO) inhibitors (concurrent use with antihistamines may prolong and intensify the anticholinergic and CNS depressant effects of antihistamines).
Brophemin side effects
See also:
What are the possible side effects of Brophemin?
Applies to Brophemin: chewable tablets, liquid, oral suspension
Other dosage forms:
- 12-hour sustained-release tablets, 24-hour sustained-release capsules
Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Anxiety; dizziness or lightheadedness; drowsiness; enlarged pupils; headache; loss of appetite; restlessness; sleeplessness; tension.
Seek medical attention right away if any of these SEVERE side effects occur while taking Brophemin:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred or double vision; chest pain; clumsiness or unsteadiness; convulsions; fast or irregular heartbeat; hallucinations; pounding in the chest; psychotic episodes (bizarre behavior); severe dry mouth, nose, or throat; shortness of breath; sore throat and fever; trouble urinating; unusual bleeding or bruising; unusual tiredness or weakness.
Brophemin contraindications
See also:
What is the most important information I should know about Brophemin?
Patients with hypersensitivity or idiosyncrasy to Brophemin. Do not use in newborn infants, premature infants, in nursing mothers, in patients with severe hypertension, severe coronary artery disease, ischemic heart disease, or in those receiving monoamine oxidase (MAO) inhibitors. Antihistamines are contraindicated in patients with narrow-angle glaucoma, urinary retention, peptic ulcer, and during an asthma attack. Antihistamines should not be used to treat lower respiratory tract conditions including asthma.
Active ingredient matches for Brophemin:
Brompheniramine maleate in Taiwan.
Unit description / dosage (Manufacturer) | Price, USD |
Brophemin 4 mg | |
List of Brophemin substitutes (brand and generic names): | |
Babycold (Thailand) | |
Baltane | |
Brompheniramine Maleate | |
Brompheniramine Pharmasant (Thailand) | |
Bronchomime "Honten" (Vietnam) | |
Bronchomime "Honten" 8 mg x 1 Bottle 200 Tablet | |
Broramin (Taiwan) | |
Broramin 4 mg x 2 x 6's | |
Broramin 4 mg x 1000's | |
Harber-Tane | |
Probahist (United States) | |
Schertane | |
Schertane Tdt | |
U.R.I. |
References
- PubChem. "BROMPHENIRAMINE". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "BROMPHENIRAMINE". http://www.drugbank.ca/drugs/DB00835 (accessed September 17, 2018).
- MeSH. "Histamine H1 Antagonists". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Brophemin are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Brophemin. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology