Bufamoxy Uses

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What is Bufamoxy?

Penicillins are used to treat infections caused by bacteria. They work by killing the bacteria or preventing their growth.

There are several different kinds of penicillins. Each is used to treat different kinds of infections. One kind of penicillin usually may not be used in place of another. In addition, penicillins are used to treat bacterial infections in many different parts of the body. They are sometimes given with other antibacterial medicines (antibiotics). Some of the penicillins may also be used for other problems as determined by your doctor. However, none of the penicillins will work for colds, flu, or other virus infections.

Penicillins are available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, penicillins are used in certain patients with the following medical conditions:

Bufamoxy indications

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Infections of the Ear, Nose, and Throat

Bufamoxy Capsules, Bufamoxy for oral suspension, Bufamoxy tablets (chewable) are indicated in the treatment of infections due to susceptible (ONLY β-lactamase–negative) isolates of Streptococcus species (α- and β-hemolytic isolates only), Streptococcus pneumoniae, Staphylococcus spp., or Haemophilus influenzae.

Infections of the Genitourinary Tract

Bufamoxy Capsules, Bufamoxy for oral suspension, Bufamoxy tablets (chewable) are indicated in the treatment of infections due to susceptible (ONLY β-lactamase–negative) isolates of Escherichia coli, Proteus mirabilis, or Enterococcus faecalis.

Infections of the Skin and Skin Structure

Bufamoxy Capsules, Bufamoxy for oral suspension, Bufamoxy tablets (chewable) are indicated in the treatment of infections due to susceptible (ONLY β-lactamase-negative) isolates of Streptococcus spp. (α- and β-hemolytic isolates only), Staphylococcus spp., or E. coli.

Infections of the Lower Respiratory Tract

Bufamoxy Capsules, Bufamoxy for oral suspension, Bufamoxy tablets (chewable) are indicated in the treatment of infections due to susceptible (ONLY β-lactamase-negative) isolates of Streptococcus spp. (α- and β-hemolytic isolates only), S. pneumoniae, Staphylococcus spp., or H. influenzae.

Helicobacter pylori Infection

Triple therapy for Helicobacter pylori with clarithromycin and lansoprazole:

Bufamoxy, in combination with clarithromycin plus lansoprazole as triple therapy, is indicated for the treatment of patients with H. pylori infection and duodenal ulcer disease (active or 1 year history of a duodenal ulcer) to eradicate H. pylori. Eradication of H. pylori has been shown to reduce the risk of duodenal ulcer recurrence.

Dual therapy for H. pylori with lansoprazole:

Bufamoxy, in combination with lansoprazole delayed-release capsules as dual therapy, is indicated for the treatment of patients with H. pylori infection and duodenal ulcer disease (active or 1 year history of a duodenal ulcer) who are either allergic or intolerant to clarithromycin or in whom resistance to clarithromycin is known or suspected. Eradication of H. pylori has been shown to reduce the risk of duodenal ulcer recurrence.

Usage

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Bufamoxy and other antibacterial drugs, Bufamoxy should be used only to treat infections that are proven or strongly suspected to be caused by bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

How should I use Bufamoxy?

Use Bufamoxy suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Bufamoxy suspension.

Uses of Bufamoxy in details

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Use: Labeled Indications

Ear, nose, and throat infections (pharyngitis/tonsillitis, otitis media):

Immediate release: Treatment of infections due to beta-lactamase-negative Streptococcus spp. (alpha- and beta-hemolytic isolates only), Streptococcus pneumoniae, Staphylococcus spp., or Haemophilus influenzae.

Extended release: Treatment of tonsillitis and/or pharyngitis due to Streptococcus pyogenes in adults and pediatric patients ≥12 years of age.

Genitourinary tract infections: Immediate release: Treatment of infections of the genitourinary tract due to beta-lactamase-negative Escherichia coli, Proteus mirabilis, or Enterococcus faecalis.

Helicobacter pylori eradication: Immediate release: Eradication of H. pylori to reduce the risk of duodenal ulcer recurrence as a component of combination therapy in patients with active or 1-year history of duodenal ulcer disease.

Lower respiratory tract infections (including pneumonia): Immediate release: Treatment of infections of the lower respiratory tract due to beta-lactamase-negative Streptococcus spp. (alpha- and beta-hemolytic strains only), S. pneumoniae, Staphylococcus spp., or H. influenzae.

Rhinosinusitis, acute bacterial: Immediate release: Treatment of infections due to beta-lactamase-negative Streptococcus spp. (alpha- and beta-hemolytic isolates only), S. pneumoniae, Staphylococcus spp., or H. influenzae.

Skin and skin structure infections: Immediate release: Treatment of infections of the skin and skin structure due to beta-lactamase-negative Streptococcus spp. (alpha- and beta-hemolytic strains only), Staphylococcus spp., or E. coli.

Off Label Uses

Actinomycosis

Data from a small retrospective study suggest that Bufamoxy may be beneficial for the treatment of actinomycosis.

Prosthetic joint infection

Based on the IDSA guidelines for the management of prosthetic joint infection (PJI), Bufamoxy is an effective and recommended agent for chronic oral antimicrobial suppression of PJI with beta-hemolytic streptococci, Enterococcus spp. (penicillin susceptible), and Cutibacterium spp. after completion of parenteral therapy.

Bufamoxy description

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A broad-spectrum semisynthetic antibiotic similar to ampicillin except that its resistance to gastric acid permits higher serum levels with oral administration. Bufamoxy is commonly prescribed with clauvanic acid (a beta lactamase inhibitor) as it is susceptible to beta-lacatamase degradation. [PubChem]

Bufamoxy dosage

Bufamoxy Dosage

Generic name: Bufamoxy 775mg

Dosage form: tablet, film coated, extended release

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Tonsillitis and/or Pharyngitis

The recommended dose of Bufamoxy is 775 mg once daily taken within 1 hour of finishing a meal for 10 days. The full 10-day course of therapy should be completed for effective treatment of tonsillitis and/or pharyngitis secondary to S. pyogenes.

Do not chew or crush tablet.

More about Bufamoxy (Bufamoxy)

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Bufamoxy interactions

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What other drugs will affect Bufamoxy?

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Allopurinol: Concurrent administration may increase the incidence of rash and other allergic skin reactions.

Anticoagulants: There are rare reports of prolongation of prothrombin time in patients concomitantly on Bufamoxy. It is recommended that appropriate monitoring is carried out when Bufamoxy is prescribed concurrently with anticoagulants.

Oral Contraceptives:

In common with other antibiotics, Bufamoxy may affect the gut flora, leading to lower oestrogen reabsorption and reduced efficacy of combined oral contraceptives.

Probenecid: Decreases the renal tubular secretion of Bufamoxy. Concurrent use with Bufamoxy may result in increased and prolonged blood levels of Bufamoxy.

Laboratory Tests: Glucose in Urine: Due to the high urinary concentrations of Bufamoxy, false positive readings are common with chemical methods.

The use of enzymatic glucose oxidase methods is recommended, as there is no interference from Bufamoxy.

Bufamoxy side effects

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What are the possible side effects of Bufamoxy?

. Overdosage

In case of overdosage, discontinue medication, treat symptomatically, and institute supportive measures as required. If the overdosage is very recent and there is no contraindication, an attempt at emesis or other means of removal of drug from the stomach may be performed. A prospective study of 51 pediatric patients at a poison-control center suggested that overdosages of less than 250 mg/kg of Bufamoxy are not associated with significant clinical symptoms and do not require gastric emptying.3

Interstitial nephritis resulting in oliguric renal failure has been reported in a small number of patients after overdosage with Bufamoxy.

Crystalluria, in some cases leading to renal failure, has also been reported after Bufamoxy overdosage in adult and pediatric patients. In case of overdosage, adequate fluid intake and diuresis should be maintained to reduce the risk of Bufamoxy crystalluria.

Renal impairment appears to be reversible with cessation of drug administration. High blood levels may occur more readily in patients with impaired renal function because of decreased renal clearance of Bufamoxy. Bufamoxy may be removed from circulation by hemodialysis.

Bufamoxy contraindications

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What is the most important information I should know about Bufamoxy?

Do not use this medication if you are allergic to Bufamoxy or to any other penicillin antibiotic, such as ampicillin (Principen, Unasyn), dicloxacillin (Dycill, Dynapen), oxacillin (Bactocill), or penicillin (Bicillin L-A, PC Pen VK, Pfizerpen), and others.

Before using Bufamoxy, tell your doctor if you are allergic to cephalosporins such as Omnicef, Cefzil, Ceftin, Keflex, and others. Also tell your doctor if you have asthma, liver or kidney disease, a bleeding or blood clotting disorder, mononucleosis (also called "mono"), or any type of allergy.

Bufamoxy can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom or diaphragm with spermicide) to prevent pregnancy while taking Bufamoxy.

Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Bufamoxy will not treat a viral infection such as the common cold or flu.

Do not share this medication with another person, even if they have the same symptoms you have.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking Bufamoxy and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.



Active ingredient matches for Bufamoxy:

Amoxicillin in Indonesia.


Unit description / dosage (Manufacturer)Price, USD
Bufamoxy 500 mg x 10 x 10's
Bufamoxy 125 mg/5 mL x 60 mL x 1's

List of Bufamoxy substitutes (brand and generic names):

Buclar 250 mg x 10 Blister x 10 Tablet
C MOX 250MG CAPSULE 1 strip / 10 capsules each (Concept Pharmaceuticals Ltd)$ 0.14
C MOX 500MG TABLET 1 strip / 10 tablets each (Concept Pharmaceuticals Ltd)$ 0.30
C-Mox 125mg DT-TAB / 100 (Corona)
C-Mox 250mg DT-TAB / 100 (Corona)
C-Mox 500mg DT-TAB / 100 (Corona)
125 mg x 100's (Corona)
250 mg x 100's (Corona)
500 mg x 100's (Corona)
C-MOX dispertab 125 mg x 10's (Corona)$ 0.22
C-MOX dispertab 250 mg x 10's (Corona)$ 0.40
C-MOX tab 500 mg x 10's (Corona)$ 0.73
Caloxyy-D Amoxicillin 250 mg, Dicloxacillin 250 mg. TAB / 100 (Zenacts)$ 7.14
100's (Zenacts)$ 7.14
CALOXYY-D tab 10's (Zenacts)$ 0.71
Camdiclox Amoxicillin 250 mg, dicloxacillin 250 mg. CAP / 10 (Trumac)$ 0.78
CAMDICLOX cap 10's (Trumac)$ 0.78
Camox 500 mg x 10 x 10's (Injecto Capta Pvt. Ltd.)
Camox 500 mg x 50 x 10's (Injecto Capta Pvt. Ltd.)
Camox 500 mg x 500's (Injecto Capta Pvt. Ltd.)
Camox 250 mg Capsule (Injecto Capta Pvt. Ltd.)$ 0.05
Camox 500 mg Capsule (Injecto Capta Pvt. Ltd.)$ 0.08
CAMOXIPHEN 500MG CAPSULE 1 strip / 10 capsules each (Zydus Cadila)$ 0.45
Cartrimox 250 mg x 100's (Ace)$ 19.78
Cartrimox 500 mg x 100's (Ace)$ 36.67
Cartrimox 125 mg/5 mL x 60 mL (Ace)$ 2.00
Cartrimox 250 mg/5 mL x 60 mL (Ace)$ 3.18
Cartrimox 100 mg/1 mL x 10 mL (Ace)$ 1.78
Cartrimox cap 250 mg 100's (Ace)$ 19.78
Cartrimox cap 500 mg 100's (Ace)$ 36.67
Cartrimox oral drops 100 mg/mL 10 mL x 1's (Ace)$ 1.78
Cartrimox oral susp 125 mg/5 mL 60 mL x 1's (Ace)$ 2.00
Cartrimox oral susp 250 mg/5 mL 60 mL x 1's (Ace)$ 3.18
Cemox 125mg DRY-SYR / 30ml (Sunrise Remedies Pvt Ltd)$ 0.22

References

  1. DailyMed. "AMOXICILLIN; CLAVULANATE POTASSIUM: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "amoxicillin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "amoxicillin". http://www.drugbank.ca/drugs/DB01060 (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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