What is Coficil-Plus?
Acetaminophen (Coficil-Plus) is a Coficil-Plus and a fever reducer.
Aspirin (Coficil-Plus) is in a group of drugs called salicylates (sa-LIS-il-ates). It works by reducing substances in the body that cause pain, fever, and inflammation.
Caffeine (Coficil-Plus) is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow.
Coficil-Plus is a combination medicine used to treat pain caused by tension headaches, migraine headaches, muscle aches, menstrual cramps, arthritis, toothaches, the common cold, or nasal congestion.
Do not use Aspirin (Coficil-Plus) for heart or blood vessel conditions unless your doctor tells you to.
Coficil-Plus may also be used for purposes not listed in this medication guide.
Coficil-Plus indications
This medication contains a combination of Coficil-Plus. Acetaminophen (Coficil-Plus) is a Coficil-Plus and a fever reducer. Aspirin (Coficil-Plus) is in a group of drugs called salicylates (sa-LIS-il-ates). It works by reducing substances in the body that cause pain, fever, and inflammation. Caffeine (Coficil-Plus) is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow.
This medication is used to treat pain caused by tension headaches, migraine headaches, muscle aches, menstrual cramps, arthritis, toothaches, the common cold, or nasal congestion.
Aspirin (Coficil-Plus) should be used for cardiovascular conditions only under the supervision of a doctor.
How should I use Coficil-Plus?
Use Coficil-Plus as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Coficil-Plus by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
- Take Coficil-Plus with a full glass of water (8 oz [240 mL]). Do not lie down for 30 minutes after taking Coficil-Plus.
- Use Coficil-Plus exactly as directed on the package, unless instructed differently by your doctor. If you are taking Coficil-Plus without a prescription, follow any warnings and precautions on the label.
- If you miss a dose of Coficil-Plus and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Coficil-Plus.
Uses of Coficil-Plus in details
This drug is used to treat mild to moderate pain (from headaches, menstrual periods, toothaches, backaches, osteoarthritis, or cold/flu aches and pains) and to reduce fever.
How to use Coficil-Plus rectal
Use this product rectally as directed. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.
If you are giving Acetaminophen (Coficil-Plus) to a child, be sure you use a product that is meant for children. Use your child's age (or weight) to find the right dose on the product package.
First, unwrap 1 suppository. Lie down on your left side with right knee bent. If giving to a child, the child may lie on the side or flat on the back. Gently push the suppository into the rectum with your finger. After inserting the suppository, if necessary, hold the buttocks together for 30 to 60 seconds to keep the suppository in place. Remain lying down for a few minutes, and avoid having a bowel movement for an hour or longer so the drug will be absorbed. The suppository is for rectal use only.
Pain medications work best if they are used as the first signs of pain occur. If you wait until the symptoms have worsened, the medication may not work as well.
Do not use more than recommended. Do not use this medication for fever for more than 3 days unless directed by your doctor. For adults, do not use this product for pain for more than 10 days (5 days in children) unless directed by your doctor. If the child has a sore throat (especially with high fever, headache, or nausea/vomiting), consult the doctor promptly.
Tell your doctor if your condition persists or worsens or if you develop new symptoms. If you think you may have a serious medical problem, get medical help right away.
Coficil-Plus dosage
Coficil-Plus Dosage
Generic name: Acetaminophen (Coficil-Plus) 250mg, Aspirin (Coficil-Plus) 250mg, Caffeine (Coficil-Plus) 65mg
Dosage form: tablet
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
- do not use more than directed
- adults: take 2 caplets with a glass of water
- if symptoms persist or worsen, ask your doctor
- do not take more than 2 caplets in 24 hours, unless directed by a doctor
- under 18 years of age: ask a doctor
More about Migraine Formula (Acetaminophen (Coficil-Plus) / Aspirin (Coficil-Plus) / Caffeine (Coficil-Plus))
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- 0 Reviews - Add your own review/rating
Consumer resources
- Other brands: Excedrin, Coficil-Plus, Coficil-Plus, Goody's Extra-Strength Headache Powders, More (7) »
Professional resources
- Coficil-Plus (FDA)
Related treatment guides
- Migraine
Coficil-Plus interactions
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What other drugs will affect Coficil-Plus?
Use of Aspirin (Coficil-Plus) with dipyridamole may result in an increase in plasma-salicylate concentrations. Drugs such as metoclopramide in patients with migraine headache result in earlier absorption of Aspirin (Coficil-Plus) and higher peak plasma-salicylate concentrations. Metoprolol may also increase peak plasma-salicylate concentrations. Salicylate intoxication has occurred in patients on high-dose salicylate regimens and carbonic anhydrase inhibitors.
Plasma-salicylate concentrations may be reduced by corticosteroids. This interaction is likely to be important in patients receiving high-dose long-term salicylate treatment. Conversely, salicylate toxicity may occur if corticosteroids are withdrawn. Also the risk of gastrointestinal bleeding and ulceration associated with Aspirin (Coficil-Plus) is increased when used with corticosteroids. Antacids may increase the excretion of Aspirin (Coficil-Plus) in alkaline urine.
Aspirin (Coficil-Plus) may enhance the activity of coumarin anticoagulants, sulfonylurea hypoglycaemic drugs, zafirlukast, methotrexate, phenytoin, and valproate. Aspirin (Coficil-Plus) diminishes the effects of uricosurics such as probenecid and sulfinpyrazone. The manufacturer of mifepristone advises of a theoretical risk that prostaglandin synthetase inhibition by Aspirin (Coficil-Plus) or NSAIDs may alter the efficacy of mifepristone.
Use of Aspirin (Coficil-Plus) with other NSAIDs should be avoided because of the increased risk of adverse effects; the cardioprotective effects of Aspirin (Coficil-Plus) may be abolished by ibuprofen. Aspirin (Coficil-Plus) may decrease the plasma concentration of some other NSAIDs, for example, fenbufen, indometacin, and piroxicam
Coficil-Plus side effects
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What are the possible side effects of Coficil-Plus?
Nausea, vomiting, stomach upset, trouble falling asleep, or a shaky/nervous feeling may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Stop taking this medication and tell your doctor right away if any of these unlikely but serious side effects occur: severe dizziness, fainting, persistent or worsening stomach pain, vomit that looks like coffee grounds, black/bloody stools, ringing in the ears, loss of hearing, irregular/fast heartbeat, signs of kidney problems (such as change in the amount of urine), signs of infection (e.g., persistent sore throat or fever), easy bruising/bleeding.
A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Coficil-Plus contraindications
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What is the most important information I should know about Coficil-Plus?
This medicaion should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Aspirin (Coficil-Plus) in this medicine can cause a serious and sometimes fatal condition called Reye’s syndrome in children. You should not use this if you are allergic to Acetaminophen (Coficil-Plus) (Tylenol), Aspirin (Coficil-Plus), or Caffeine (Coficil-Plus), or if you have:
a recent history of stomach or intestinal bleeding;
liver disease;
asthma or severe allergic reaction caused by taking Aspirin (Coficil-Plus) or a non-steroidal anti-inflammatory drug (NSAID), especially "Aspirin (Coficil-Plus) triad syndrome"; or
if you are allergic to an NSAID such as Advil, Motrin, Aleve, Orudis, Indocin, Lodine, Voltaren, Toradol, Mobic, Relafen, Feldene, and others.
Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:
asthma or seasonal allergies;
fever with a stiff neck;
a stomach ulcer, heartburn, or stomach pain;
a bleeding or blood clotting disorder such as hemophilia;
diabetes; or
gout.
Active ingredient matches for Coficil-Plus:
Acetaminophen/Aspirin/Caffeine
| Unit description / dosage (Manufacturer) | Price, USD |
| Tablet; Oral; Acetaminophen 100 mg; Aspirin 300 mg; Caffeine 50 mg | |
List of Coficil-Plus substitutes (brand and generic names): | |
| Cibalena A (Brazil) | |
| ConRx Pain Reliever | |
| Contre-Douleurs (Switzerland) | |
| CVS Extra Strength Headache Relief | |
| Dolofarma (Spain) | |
| Dolvis (Italy) | |
| Doralem (Brazil) | |
| Doscafis (Spain) | |
| Drin (Italy) | |
| Duan (Austria) | |
| Ephimigrin (Romania) | |
| Tablet; Oral; Acetaminophen 230 mg; Aspirin 350 mg; Caffeine Anhydrous 20 mg (Europharm) | |
| Excedrin Capsules | |
| Excedrin Express Gels | |
| Excedrin Extra Strength | |
| Excedrin Extra Strength Geltab | |
| Excedrin Geltab | |
| Excedrin Menstrual Complete | |
| Excedrin Menstrual Express Gels | |
| Excedrin Migraine | |
| Tablet; Oral; Acetaminophen 250 mg; Aspirin 250 mg; Caffeine 65 mg (Novartis) | |
| Excedrin Migraine Drug Facts | |
| Excedrin Migraine Geltab | |
| Extra Pain Relief | |
| Extra Power Pain Reliever (United Kingdom) | |
| Fineural N (Germany) | |
| Fribagyl sans Codeine (Switzerland) | |
| Gelpirin (United States) | |
| Genace | |
| Goody’s Headache Powders | |
| Goody's Cool Orange | |
| Powder; Oral; Acetaminophen 325 mg; Aspirin 500 mg; Caffeine 65 mg | |
| Goody's Extra Strength | |
| Powder; Oral; Acetaminophen 260 mg; Aspirin 520 mg; Caffeine 32.5 mg | |
| Goody's Extra-Strength Headache Powders Powder Packet | |
| Goody's Headache Powders | |
| Powder; Oral; Acetaminophen; Aspirin; Caffeine | |
| Goodys Extra Strength | |
| Goodys Headache Powders | |
| Grand-Pa Headache (South Africa) | |
| HA-Tabletten N (Germany) | |
| Tablet; Oral; Acetaminophen; Aspirin; Caffeine (Boehringer ingelheim) | |
| Headrin Extra Strength (United States) | |
| Herbin-Stodin (Germany) | |
| Iralgesic (Russia) | |
| Tablet; Oral; Acetaminophen 162.5 mg; Aspirin 325 mg; Caffeine 32.5 mg (Darou pakhsh) | |
| Kafedrine | |
See 132 substitutes for Coficil-Plus | |
References
- DailyMed. "CAFFEINE; ERGOTAMINE TARTRATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "ASPIRIN; DIPYRIDAMOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "ACETAMINOPHEN; ASPIRIN; CAFFEINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Coficil-Plus are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Coficil-Plus. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yet1 consumer reported age
| Users | % | ||
|---|---|---|---|
| 46-60 | 1 | 100.0% | |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
