Concentrat VO 59-1 Neomycine 80 Porc Uses

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What is Concentrat VO 59-1 Neomycine 80 Porc?

Concentrat VO 59-1 Neomycine 80 Porc is an antibiotic that fights bacteria in the body.

Concentrat VO 59-1 Neomycine 80 Porc is used to reduce the risk of infection during surgery of your intestines. Concentrat VO 59-1 Neomycine 80 Porc is also used to reduce the symptoms of hepatic coma.

Concentrat VO 59-1 Neomycine 80 Porc may also be used for purposes not listed in this medication guide.

Concentrat VO 59-1 Neomycine 80 Porc indications

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To reduce the development of drug-resistant bacteria and maintain the effectiveness of Concentrat VO 59-1 Neomycine 80 Porc Sulfate tablets and other antibacterial drugs, Concentrat VO 59-1 Neomycine 80 Porc Sulfate tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Suppression of Intestinal Bacteria

Concentrat VO 59-1 Neomycine 80 Porc Sulfate tablets are indicated as adjunctive therapy as part of a regimen for the suppression of the normal bacterial flora of the bowel, e.g., preoperative preparation of the bowel. It is given concomitantly with erythromycin enteric-coated base.

Hepatic Coma (Portal-Systemic Encephalopathy)

Concentrat VO 59-1 Neomycine 80 Porc Sulfate has been shown to be effective adjunctive therapy in hepatic coma by reduction of the ammonia-forming bacteria in the intestinal tract. The subsequent reduction in blood ammonia has resulted in neurologic improvement.

How should I use Concentrat VO 59-1 Neomycine 80 Porc?

Use Concentrat VO 59-1 Neomycine 80 Porc solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Concentrat VO 59-1 Neomycine 80 Porc solution.

Uses of Concentrat VO 59-1 Neomycine 80 Porc in details

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Oral Concentrat VO 59-1 Neomycine 80 Porc is used before the operation of the gut to kill the bacteria which normally live in the gut that may cause a serious infection and in treatment of patients with coma due to liver disease (hepatic coma).

Concentrat VO 59-1 Neomycine 80 Porc description

A component of Concentrat VO 59-1 Neomycine 80 Porc that is produced by Streptomyces fradiae. On hydrolysis it yields neamine and neobiosamine B. (From Merck Index, 11th ed). Concentrat VO 59-1 Neomycine 80 Porc is a bactericidal aminoglycoside antibiotic that binds to the 30S ribosome of susceptible organisms. Binding interferes with mRNA binding and acceptor tRNA sites and results in the production of non-functional or toxic peptides.

Concentrat VO 59-1 Neomycine 80 Porc dosage

Concentrat VO 59-1 Neomycine 80 Porc Dosage

Generic name: Concentrat VO 59-1 Neomycine 80 Porc SULFATE 87.5mg in 5mL

Dosage form: oral solution

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The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

To minimize the risk of toxicity use the lowest possible dose and the shortest possible treatment period to control the condition. Treatment for periods longer than two weeks is not recommended.

Hepatic coma

For use as an adjunct in the management of hepatic coma, the recommended dose is 4 to 12 grams per day given in the following regimen:

  1. Withdraw protein from diet. Avoid use of diuretic agents.

  2. Give supportive therapy including blood products, as indicated.

  3. Give Concentrat VO 59-1 Neomycine 80 Porc

    Oral Solution in doses of four to twelve grams of Concentrat VO 59-1 Neomycine 80 Porc sulfate per day in divided doses.

    Treatment should be continued over a period of five to six days during which time protein should be returned incrementally to the diet.

  4. If less potentially toxic drugs cannot be used for chronic hepatic insufficiency, Concentrat VO 59-1 Neomycine 80 Porc sulfate in doses of up to four grams daily may be necessary. The risks for the development of Concentrat VO 59-1 Neomycine 80 Porc induced toxicity progressively increase when the treatment must be extended to preserve the life of a patient with hepatic encephalopathy who has failed to fully respond. Frequent periodic monitoring of these patients to ascertain the presence of drug toxicity is mandatory. Also, Concentrat VO 59-1 Neomycine 80 Porc serum concentrations should be monitored to avoid potentially toxic levels. The benefits to the patient should be weighed against the risks of nephrotoxicity, permanent ototoxicity and neuromuscular blockade following the accumulation of Concentrat VO 59-1 Neomycine 80 Porc in the tissues.

More about Concentrat VO 59-1 Neomycine 80 Porc (Concentrat VO 59-1 Neomycine 80 Porc)

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Concentrat VO 59-1 Neomycine 80 Porc interactions

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What other drugs will affect Concentrat VO 59-1 Neomycine 80 Porc?

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Caution should be taken in concurrent or serial use of other neurotoxic and/ or nephrotoxic drugs because of possible enhancement of the nephrotoxicity and/or ototoxicity of Concentrat VO 59-1 Neomycine 80 Porc.

Caution should also be taken in concurrent or serial use of other aminoglycosides and polymyxins because they may enhance Concentrat VO 59-1 Neomycine 80 Porc's nephrotoxicity and/or ototoxicity and potentiate Concentrat VO 59-1 Neomycine 80 Porc sulfate's neuromuscular blocking effects.

Oral Concentrat VO 59-1 Neomycine 80 Porc inhibits the gastrointestinal absorption of penicillin V, oral vitamin B-12, methotrexate and 5-fluorouracil. The gastrointestinal absorption of digoxin also appears to be inhibited. Therefore, digoxin serum levels should be monitored.

Oral Concentrat VO 59-1 Neomycine 80 Porc sulfate may enhance the effect of coumarin in anticoagulants by decreasing vitamin K availability.

Concentrat VO 59-1 Neomycine 80 Porc side effects

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What are the possible side effects of Concentrat VO 59-1 Neomycine 80 Porc?

Applies to Concentrat VO 59-1 Neomycine 80 Porc: oral solution, oral tablet

In addition to its needed effects, some unwanted effects may be caused by Concentrat VO 59-1 Neomycine 80 Porc (the active ingredient contained in Concentrat VO 59-1 Neomycine 80 Porc). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking Concentrat VO 59-1 Neomycine 80 Porc:

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Minor Side Effects

Some of the side effects that can occur with Concentrat VO 59-1 Neomycine 80 Porc may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

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Concentrat VO 59-1 Neomycine 80 Porc contraindications

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What is the most important information I should know about Concentrat VO 59-1 Neomycine 80 Porc?

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You should not take this medicine if you are allergic to Concentrat VO 59-1 Neomycine 80 Porc or similar antibiotics such as amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), paromomycin (Humatin, Paromycin), streptomycin, or tobramycin (Nebcin, Tobi).

You should not take Concentrat VO 59-1 Neomycine 80 Porc if you have ulcerative colitis, Crohn's disease, a blockage in your intestines, or other inflammatory bowel disease.

Do not use Concentrat VO 59-1 Neomycine 80 Porc if you are pregnant. It could harm the unborn baby.

Before you take Concentrat VO 59-1 Neomycine 80 Porc, tell your doctor if you have kidney disease, myasthenia gravis, or Parkinson's disease.

Never take Concentrat VO 59-1 Neomycine 80 Porc in larger amounts than recommended, or for longer than 2 weeks. High doses or long-term use of Concentrat VO 59-1 Neomycine 80 Porc can cause serious kidney problems, or hearing loss that may not be reversible. The longer you take Concentrat VO 59-1 Neomycine 80 Porc, the more likely you are to develop these serious side effects.

To be sure this medication is not causing harmful effects, your kidney function, and your nerve and muscle function will need to be tested often. You may also need hearing tests. Concentrat VO 59-1 Neomycine 80 Porc can have long lasting effects on your body. Do not miss any follow up visits to your doctor for blood or urine tests.

Concentrat VO 59-1 Neomycine 80 Porc can harm your kidneys, and this effect is increased when you also use certain other medicines harmful to the kidneys. Before using Concentrat VO 59-1 Neomycine 80 Porc, tell your doctor about all other medicines you use. Many other drugs (including some over-the-counter medicines) can be harmful to the kidneys.

If you are being treated for hepatic coma, avoid eating foods that are high in protein. Follow your doctor's instructions about any other restrictions on food, beverages, or activity.



Active ingredient matches for Concentrat VO 59-1 Neomycine 80 Porc:

Neomycin in France.


List of Concentrat VO 59-1 Neomycine 80 Porc substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Decacin B E/E Drop (Calibre Pharmaceutical Pvt. Ltd.)$ 0.06
Decdan N E/E 3 ml Drop (Merind Ltd (Wockhardt Ltd))$ 0.03
Decol N Eye 5 ml Drop (Intas Laboratories Pvt Ltd)$ 0.13
Decol N 0.5%/0.1% Drop (Intas Laboratories Pvt Ltd)$ 0.10
Dermowin NM Skin 10 gm Cream (Wings Pharmaceuticals (P) Ltd.)$ 0.14
Dermozyme Skin 10 gm Ointment (Concept Pharmaceuticals Ltd.)$ 0.30
Dexa N E/E Drop (Winmac Laboratories Limited)$ 0.04
Dexalog N Eye Drop (Prem Pharmaceuticals Ltd.)$ 0.10
Dibet N Skin 10 gm Cream (Neuron Pharma Pvt. Ltd.)$ 0.02
Flumed N Skin 10 gm Cream (Mediwin Pharmaceuticals)$ 0.24
Fluted 10 g
Fluted 100 g
Flutop N Skin 15 gm Cream (Novasearch Dermocare (Ultramark Healthcare Pvt Ltd))$ 0.02
Klosoft N Skin 15 gm Ointment (Sandoz Pvt.Ltd)$ 0.29
KLOSOFT N 0.05%/0.5% CREAM 1 tube / 15 gm cream each (Sandoz Pvt.Ltd)$ 0.29
Klosoft N 0.05%/5% Cream (Sandoz Pvt.Ltd)$ 0.29

References

  1. DailyMed. "HYDROCORTISONE; NEOMYCIN SULFATE; POLYMYXIN B SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "neomycin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "neomycin". http://www.drugbank.ca/drugs/DB00452 (accessed September 17, 2018).

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