Corivin-PAED Uses

How do you administer this medicine?
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What is Corivin-PAED?

Relieving nasal congestion due to the common cold, hay fever, other upper respiratory tract allergies, or sinus infection. It also soothes nasal discomfort caused by dryness. It may also be used to treat other conditions as determined by your doctor.

Corivin-PAED spray is a decongestant. It works by shrinking swollen and congested nasal tissues (mucous membranes) by constricting blood vessels. This results in relief of congestion (stuffy feeling), improved drainage of mucus, and improved breathing through the nose. Local application (eg, nose drops and sprays) causes more intense and rapid vasoconstriction than oral medicines (eg, tablets, syrups).

Corivin-PAED indications

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Corivin-PAED nasal is a decongestant. It works by constricting (shrinking) blood vessels (veins and arteries) in the body. The nasal formulation acts directly on the blood vessels in the nasal tissues. Constriction of the blood vessels in the nose and sinuses leads to a decrease in congestion.

Corivin-PAED nasal is used to treat congestion associated with allergies, hay fever, sinus irritation, and the common cold.

How should I use Corivin-PAED?

Use Corivin-PAED spray as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Corivin-PAED spray.

Uses of Corivin-PAED in details

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Corivin-PAED is used for relief of the blocked; congested nose and sinuses caused by colds and allergies such as hay fever.

Corivin-PAED description

A nasal vasoconstricting decongestant drug which acts by binding to the same receptors as adrenaline. It is applied as a spray or as drops into the nose to ease inflammation and congestion of the nasal passageways. It binds alpha-adrenergic receptors to activate the adrenal system which causes systemic vasoconstriction, thereby easing nasal congestion.

Corivin-PAED dosage

Usual Pediatric Dose for Nasal Congestion

Corivin-PAED nasal 0.05% spray:

2 to 12 years: 1 to 2 sprays in each nostril every 8 to 10 hours not to exceed 3 doses daily. Do not use for more than 3 days.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available

Corivin-PAED interactions

Do not use Corivin-PAED nasal if you have taken a monoamine oxidase (MAO) inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days.

Although drug interactions between topical nasal decongestants and other medications taken by mouth are not expected, they can occur. Rarely, Corivin-PAED nasal may interact with the following medicines:

furazolidone (Furoxone);

guanethidine (Ismelin);

indomethacin (Indocin);

methyldopa (Aldomet);

bromocriptine (Parlodel);

caffeine in cola, tea, coffee, chocolate, and other products;

theophylline (Theo-Dur, Theochron, Theolair, others);

tricyclic antidepressants such as amitriptyline (Elavil, Endep), doxepin (Sinequan), clomipramine (Anafranil), and nortriptyline (Pamelor), and others; and

phenothiazines such as chlorpromazine (Thorazine), thioridazine (Mellaril), and prochlorperazine (Compazine), and others

Corivin-PAED side effects

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What are the possible side effects of Corivin-PAED?

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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeat;
  • confusion, hallucinations, unusual thoughts or behavior;
  • severe dizziness, anxiety, restless feeling, or nervousness;
  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);
  • confusion, hallucinations, unusual thoughts or behavior;
  • easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or
  • urinating less than usual or not at all.

    Keep taking the medication and talk to your doctor if you have any of these less serious side effects:

  • blurred vision;
  • dry mouth;
  • nausea, stomach pain, constipation;
  • mild loss of appetite, stomach upset;
  • warmth, tingling, or redness under your skin;
  • sleep problems (insomnia);
  • restless or excitability (especially in children);
  • skin rash or itching;
  • dizziness, drowsiness;
  • problems with memory or concentration; or
  • ringing in your ears.

    Corivin-PAED contraindications

    See also:
    What is the most important information I should know about Corivin-PAED?

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    has narrow-angle glaucoma or rhinitis sicca

    is allergic to Corivin-PAED or any of the ingredients of the medication Corivin-PAED drops like other vasoconstrictor drops should not be used without medical supervision in patients with heart disease, hypertension, thyroid disease and hypertrophy of prostate.

    Active ingredient matches for Corivin-PAED:

    Xylometazoline in India.


    Unit description / dosage (Manufacturer)Price, USD
    CORIVIN-PAED nasal drops 0.05 % w/v x 10ml (Olcare (Fusion))$ 0.35

    List of Corivin-PAED substitutes (brand and generic names):

    CORIVEX PAED nasal drops 0.05 % w/v x 10ml (Olcare (Excare))$ 0.35
    0.1 % x 10ml (Lee Benz (Admac Pharma Ltd.))$ 0.36
    Cyfer 0.1% N-DPS / 10ml (Lee Benz (Admac Pharma Ltd.))$ 0.36
    Cyfer Nasal 10 ml Drop (Lee Benz (Admac Pharma Ltd.))$ 0.36
    Cyfer 100 mg+1.5 mg+7.5 mcg Tablet (Lee Benz (Admac Pharma Ltd.))$ 0.09
    CYFER nasal drops 0.1 % x 10ml (Lee Benz (Admac Pharma Ltd.))$ 0.36
    Cyfer 0.1% N-DPS / 10ml (Lee Benz (Admac Pharma Ltd.))$ 0.36
    0.05 % w/v x 10ml (Admac (Lee Benz))$ 0.34
    Cyfer-P 0.05% w/v N-DPS / 10ml (Admac (Lee Benz))$ 0.34
    CYFER-P nasal drops 0.05 % w/v x 10ml (Admac (Lee Benz))$ 0.34
    Cyfer-P 0.05% w/v N-DPS / 10ml (Admac (Lee Benz))$ 0.34
    Ointment; Topical; Camphor 5%; Eucalyptus Oil 1.5%; Menthol 3% (Adison Laboratories)
    0.1 % w/v x 10ml (Adison Laboratories)$ 0.35
    0.05 % w/v x 10ml (Adison Laboratories)$ 0.24
    Decon 500's (Adison Laboratories)
    Decon 0.05% w/v P- N- DROPS / 10ml (Adison Laboratories)$ 0.24
    Decon 0.1% w/v N- DROPS / 10ml (Adison Laboratories)$ 0.35
    Decon 25 mg Injection (Adison Laboratories)$ 0.70
    Decon Nasal 10 ml Drop (Adison Laboratories)$ 0.37
    Decon 50 mg Injection (Adison Laboratories)$ 1.22
    Decon Eye Drop (Adison Laboratories)$ 0.16
    Decon Nasal 0.05% Drop (Adison Laboratories)$ 0.44
    DECON 0.1% W/V NASAL DROPS 1 packet / 10 ML nasal drops each (Adison Laboratories)$ 0.57
    DECON 0.1% W/V SPRAY 1 packet / 10 ML spray each (Adison Laboratories)$ 0.57
    DECON NEW 0.1% W/V SPRAY 1 packet / 10 ML spray each (Adison Laboratories)$ 0.57
    DECON PAED 0.05%W/V DROP 1 packet / 10 ML drop each (Adison Laboratories)$ 0.57
    DECON nasal drops 0.1 % w/v x 10ml (Adison Laboratories)$ 0.35
    DECON P- nasal drops 0.05 % w/v x 10ml (Adison Laboratories)$ 0.24
    Decon 0.1% w/v Nasal Drops (Adison Laboratories)$ 0.57
    Decon 0.1% w/v Nasal Spray (Adison Laboratories)$ 0.57
    Decon 0.05%w/v Nasal Drops (Adison Laboratories)$ 0.57
    Solution; Nasal; Xylometazoline Hydrochloride 0.1%
    Decongest Nasal solution 0.1 % (Teva Canada Limited (Canada))
    Spray; Nasal; Xylometazoline Hydrochloride 0.1% (Confab)
    Solution; Nasal; Xylometazoline Hydrochloride 0.1% (Confab)

    References

    1. PubChem. "xylometazoline". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
    2. DrugBank. "xylometazoline". http://www.drugbank.ca/drugs/DB06694 (accessed September 17, 2018).
    3. MeSH. "Nasal Decongestants". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).

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    Information checked by Dr. Sachin Kumar, MD Pharmacology

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