Dicycloverine indications
For the treatment of functional disturbances of gastrointestinal motility eg, irritable bowel syndrome and renal and biliary colic. As with other antispasmodics, Dicycloverine has limited efficacy in the treatment of these disorders and should be used only if other measures (eg, diet) have been of little or no benefit.
Dicycloverine has been used alone or in combination with phenobarbital in the treatment of infant colic and acute enterocolitis but lacks substantial evidence of efficacy in these conditions. Infant colic is considered a benign and self-limiting condition.
Dicycloverine description
A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms.
Dicycloverine dosage
Oral
Gastrointestinal tract spasm
Adult: 10-20 mg tid.
Child: 2-12 yr: 10 mg tid; 6 mth-2 yr: 5-10 mg 3-4 times daily.
Elderly:
Intramuscular
Gastrointestinal tract spasm
Adult: 20 mg 4 times a day given only for 1-2 days. Replace with oral therapy as soon as possible.
Dicycloverine interactions
The following agents may increase certain actions or side effects of anticholinergic drugs. amantadine antiarrhythmic agents of class (e.g. quinidine), antihistamines antipsychotic agents (e.g. phenothiazines), benzodiazepines. MAO inhibitors, narcotic analgesics (e.g., meperidine), nitrates and nitrites, sympathomimetic agents, tricyclic antidepressants, and other drugs having anticholinergic activity.
Anticholinergics antagonize the effects of antiglaucoma agents. Anticholinergic drugs in the presence of increased intraocular pressure may be hazardous when taken concurrently with agents such as corti costeroids..
Anticholinergic agents may affect gastrointestinal absorption of various drugs, such as slowly dissolving dosage forms of digoxin; increased serum digoxin concentrations may result.
Anticholinergic drugs may antagonize the effects of the drugs that alter gastrointestinal motility, such as metoclopramide. Because antacids may interfere with the absorption of anticholinergic agents, simultaneous use of these drugs should be avoided.
The inhibiting effects of anticholinergic drugs on gastric hydrochloric acid secretion are antagonized by agents used to treat achlorhydria and those used to test gastric secretion.
Dicycloverine side effects
Dryness of mouth w/ difficulty in swallowing & talking, thirst, reduced bronchial secretions, mydriasis w/ cycloplegia & photophobia, flushing & dryness of the skin, transient bradycardia w/ palpitations & arrhythmias, difficulty in micturition, constipation.
Dicycloverine contraindications
Dicycloverine should not be given to patients with obstructive uropathy, obstructive disease of the GIT, ulcerative colitis, reflux esophagitis, hypersensitivity to Dicycloverine HCl and nursing mothers.
Active ingredient matches for Dicycloverine:
Dicycloverine
List of Dicycloverine substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Dicycloverin Hydrochloride | |
| Dicycloverine Hydrochloride Zentiva (United Kingdom) | |
| Dicycloverine Zentiva (United Kingdom) | |
| Dicycloverinum | |
| Dicycloverinum [Inn-Latin] | |
| Dicymed (Philippines) | |
| Dicymine (Hong Kong, Thailand) | |
| Dicymine 10 mg x 1, 000's (Christo) | |
| Dicymine Co 3.6 L (Christo) | |
| Dicymine 15 mg x 1, 000's (Christo) | |
| Diethylaminocarbethoxybicyclohexyl Hydrochloride | |
| Dilomin (Philippines) | |
| Dilomin 10 mg x 100's (Am-europharma) | $ 13.52 |
| Dilomin 10 mg/5 mL x 60 mL (Am-europharma) | $ 0.73 |
| Dilomine | |
| Diocyl | |
| Diocyl Hydrochloride | |
| DIOSPAS (India) | |
| 10 mg x 250's (Shalaks Pharmaceuticals Pvt. Ltd.) | $ 0.90 |
| 10 mg x 500's (Shalaks Pharmaceuticals Pvt. Ltd.) | $ 0.91 |
| 20 mg x 100's (Shalaks Pharmaceuticals Pvt. Ltd.) | $ 0.59 |
| 20 mg x 500's (Shalaks Pharmaceuticals Pvt. Ltd.) | $ 1.45 |
| Diospas 10mg TAB / 250 (Shalaks Pharmaceuticals Pvt. Ltd.) | $ 0.90 |
| Diospas 10mg TAB / 500 (Shalaks Pharmaceuticals Pvt. Ltd.) | $ 0.91 |
| Diospas 20mg TAB / 100 (Shalaks Pharmaceuticals Pvt. Ltd.) | $ 0.59 |
| Diospas 20mg TAB / 500 (Shalaks Pharmaceuticals Pvt. Ltd.) | $ 1.45 |
| Diospas 10 mg Tablet (Shalaks Pharmaceuticals Pvt. Ltd.) | $ 0.00 |
| Diospas 20 mg Tablet (Shalaks Pharmaceuticals Pvt. Ltd.) | $ 0.01 |
| DIOSPAS tab 10 mg x 20's (Shalaks Pharmaceuticals Pvt. Ltd.) | $ 0.05 |
| DIOSPAS tab 20 mg x 10's (Shalaks Pharmaceuticals Pvt. Ltd.) | $ 0.06 |
| Diospas 10mg TAB / 250 (Shalaks Pharmaceuticals Pvt. Ltd.) | $ 0.90 |
| Diospas 10mg TAB / 500 (Shalaks Pharmaceuticals Pvt. Ltd.) | $ 0.91 |
| Diospas 20mg TAB / 100 (Shalaks Pharmaceuticals Pvt. Ltd.) | $ 0.59 |
| Diospas 20mg TAB / 500 (Shalaks Pharmaceuticals Pvt. Ltd.) | $ 1.45 |
| Diospas NA Drop (Shalaks Pharmaceuticals Pvt. Ltd.) | $ 0.36 |
| DIOSPAS (DIVINE) | |
| DIOSPAS DROPS 1 packet / 10 ML drop each (Divine Lifecare Pvt Ltd) | $ 0.36 |
| Dirin (Bangladesh) | |
| Diverin (Bangladesh) | |
| Dysmen Injection (India) | |
| Dysmen Injections | |
| Injectable; Injection; Dicyclomine Hydrochloride | |
| DYSMEN-INJ (India) | |
| 10 mg x 1 mL x 10ml (Svizera) | $ 0.12 |
| Dysmen-Inj 10mg x 1mL INJ / 10ml (Svizera) | $ 0.12 |
| DYSMEN-INJ inj 10 mg x 1 mL x 10ml (Svizera) | $ 0.12 |
| Dysmen-Inj 10mg x 1mL INJ / 10ml (Svizera) | $ 0.12 |
| Dyspas (India) | |
| 10's (Embiotic Laboratories (P) Ltd.) | $ 0.17 |
See 276 substitutes for Dicycloverine | |
References
- PubChem. "dicyclomine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "dicyclomine". http://www.drugbank.ca/drugs/DB00804 (accessed September 17, 2018).
- DTP/NCI. "Merbentyl: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Dicycloverine are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Dicycloverine. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yet1 consumer reported time for results
To what extent do I have to use Dicycloverine before I begin to see changes in my health conditions?As part of the reports released by ndrugs.com website users, it takes 1 day and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Dicycloverine. To get the time effectiveness of using Dicycloverine drug by other patients, please click here.
| Users | % | ||
|---|---|---|---|
| 1 day | 1 | 100.0% | |
2 consumers reported age
| Users | % | ||
|---|---|---|---|
| 30-45 | 2 | 100.0% | |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
