Drydex indications
Drydex hydrochloride SYRUP indicated for cough associated with wheeziness (bronchospasm) and tenacious phlegm (sputum).
Uses of Drydex in details
Drydex is used to treat breathing difficulties caused by excessive mucus secretions in the air passages associated with respiratory tract infections.
Drydex description
Each tablet also contains lactose, maize or potato starch, gelatine and magnesium stearate as excipients.
The oral/inhalation solution also contains tartaric acid and methyl parahydroxybenzoate as excipients.
The syrup also contains tartaric acid, benzoic acid, sodium carboxymethylcellulose, glycerol, sorbitol solution, pharma flavor and ethanol as excipients.
Each capsule also contains lactose, cornstarch and magnesium stearate as excipients.
Drydex HCl is N-cyclohexyl-N-methyl-(2-amino-3,5-dibromobenzyl)amine hydrochloride.
Drydex dosage
Unless otherwise prescribed, the following doses are recommended:
Tablet: Adults and Children >12 years: 8 mg (1 tab) thrice daily; 6-12 years: 4 mg (½ tab) thrice daily; 2-6 years: 4 mg (½ tab) twice daily.
Oral Solution:
Adults and Children >12 years: 4 mL thrice daily; 6-12 years: 2 mL thrice daily; 2-6 years: 20 drops thrice daily; <2 years: 10 drops thrice daily.Inhalation Solution (with aerosol apparatus): It is generally recommended to warm inhalation solution to body temperature before inhalation. Patients with bronchial asthma may be advised to commencing inhalation after they have taken their regular bronchospasmolytic therapy.
Adults: 4 mL. Children >12 years: 2 mL; 6-12 years: 1 mL; 2-6 years: 10 drops; <2 years: 5 drops. All doses to be taken twice daily.
The solution may be diluted 1:1 in physiological saline solution. In order to avoid precipitation, the solution should be inhaled immediately after mixing. The combined administration of inhalation and oral application intensifies the effect, and is especially suited for the commencement of treatment in cases where the full effect is to be reached quickly.
Syrup: Adults and Children >12 years: 5 ml (1 tsp) thrice daily.
At commencement of treatment, it may be necessary to increase the total daily dose up to 48 mg in adults.
The syrup is sugar-free and therefore suitable for diabetics and small children.
Ampoule: Severe cases, before and after surgical intervention: 1 amp SC, IM or IV (duration of injection: 2-3 min) 2-3 times daily.
Capsule: Adults: 1 cap 3 times daily.
It is recommended for the initial phase of treatment usually lasting not more than a week.
Patients being treated with Drydex should be notified of an expected increase in the flow of secretions.
Drydex interactions
A reduction in dose of cardiac glycosides (e.g. digitalis) and quinidine might become necessary in patients suffering from congestive cardiac failure because of the positive inotropic effect of orciprenaline sulphate.
Drydex hydrochloride SYRUP should not be administered concomitantly with beta-blocking agents, due to orciprenaline’s reversal of anti-hypertensive action.
The concomitant use of other sympathomimetic agents should be carefully controlled to avoid potentiation of effects.
Drydex side effects
Drydex’s pharmacological action may lead to gastric irritation. A transient rise in serum aminotransferase values have been reported due to Drydex.
Orciprenaline sulphate, as a sympathomimetic agent, may precipitate a wide range of adverse effects. Side-effects include fear; anxiety, restlessness, tremor, insomnia, confusion, irritability, weakness and psychotic states. Appetite may be reduced and nausea and vomiting may occur. A rise in blood pressure which may produce cerebral haemorrhage and pulmonary oedema, tachycardia and cardiac arrhythmias, anginal pain, palpitations, and cardiac arrest. Hypotension with dizziness and fainting and flushing may occur. Other effects that may occur include difficulty in micturition and urinary retention; dyspnoea; weakness; headache; disturbances of glucose metabolism; sweating and hypersalivation. Muscle cramps or twitching or unpleasant taste may occur.
Drydex contraindications
Drydex hydrochloride SYRUP is contra-indicated in patients with known hypersensitivity to sympathomimetic amines or any of the other ingredients; hypertrophic obstructive cardiomyopathy; and tachyarrhythmia.
Sympathomimetics, such as orciprenaline sulphate, may interact with monoamine oxidase inhibitors (MAOI), and therefore Drydex hydrochloride SYRUP should not be given to patients receiving such treatment or within 14 days of MAOI treatment termination.
Safety in pregnancy and lactation has not been established.
Active ingredient matches for Drydex:
Bromhexine in India.
Ammonium chloride/bromhexine hydrochloride/dextromethorphan hydrobromide/menthol in India.
| Unit description / dosage (Manufacturer) | Price, USD |
| Drydex Bromhexine hydrochloride 4 mg, Menthol 2.5 mg, Dextromethorphan hydrobromide5 mg, Ammonium chloride 50mg/5 mL. SYR / 100ml | $ 0.59 |
| Drydex Bromhexine hydrochloride 4 mg, Menthol 2.5 mg, Dextromethorphan hydrobromide5 mg, Ammonium chloride 50mg/5 mL. SYR / 50ml | $ 0.35 |
| 100ml | $ 0.59 |
| 50ml | $ 0.35 |
| Drydex 100 ml Syrup | $ 0.03 |
| Drydex 50 ml Syrup | $ 0.03 |
| DRYDEX syr 100ml (Neclife (Neccare)) | $ 0.59 |
| DRYDEX syr 50ml (Neclife (Neccare)) | $ 0.35 |
List of Drydex substitutes (brand and generic names): | |
| Dry Cough Syrup (United Kingdom) | |
| Dry Cough Syrup syrup 15 mg (Aah) | |
| Drydex T | |
| Drydex T 50 ml Syrup (Nectar Life Sciences Ltd.) | $ 0.04 |
| Drydex T 100 ml Syrup (Nectar Life Sciences Ltd.) | $ 0.03 |
| Dulinct (India) | |
| Dulinct Dextromethorphan 5 mg, Chlorpheniramine maleate 2.5mg, Guaiphenesin 50 mg, Ammonium chloride 60 mg. SYR / 100ml (Eva Biotech) | $ 0.55 |
| 100ml (Eva Biotech) | $ 0.55 |
| DULINCT syr 100ml (Eva Biotech) | $ 0.55 |
| Dur-Elix (Philippines) | |
| Duract Max Strength Cough | |
| Duract Max Strength Cough tablet, orally disintegrating 30 mg/1 (Matrixx Initiatives, Inc. (US)) | |
| Duro-Tuss Mucolytic (New Zealand, Singapore) | |
| Duro-Tuss Mucolytic 12 mg/5 mL x 200 mL (iNova) | |
| Duro-Tuss Mucolytic syr 12 mg/5 mL 200 mL x 1's (iNova) | |
| Duro-Tuss Mucolytic Cough Liquid (Singapore) | |
| Dutross (Thailand) | |
| Dutross 8 mg x 25 x 10's (Tnp) | |
| Dutross 4 mg/5 mL x 60 mL (Tnp) | |
| Eaco (Taiwan) | |
| Eaco 30 mg x 1000's | |
| Easco (Taiwan) | |
| Easco 20 mg | |
| easybronchial forte 3 mg/ml (Austria) | |
| easybronchial junior 1.5 mg/ml (Austria) | |
| Ecodil (India) | |
| Ecodil Paracetamol 170 mg, Dextromethorphan hydrobromide5 mg, Chlorpheniramine maleate1.5 mg, Phenylephrinehydrochloride 2.5 mg. P-SYR / 50ml (Maan Pharma) | $ 0.34 |
| 50ml (Maan Pharma) | $ 0.34 |
| ECODIL P- syr 50ml (Maan Pharma) | $ 0.34 |
| Ecodil-DH (India) | |
| Ecodil-DH Dextromethorphan hydrobromide10 mg, Phenylephrinehydrochloride 5 mg, Chlorpheniramine maleate 2 mg. SYR / 100ml (Maan Pharma) | $ 0.57 |
| Ecodil-DH Dextromethorphan hydrobromide10 mg, Phenylephrinehydrochloride 5 mg, Chlorpheniramine maleate 2 mg. SYR / 50ml (Maan Pharma) | $ 0.39 |
| 100ml (Maan Pharma) | $ 0.57 |
| 50ml (Maan Pharma) | $ 0.39 |
| ECODIL-DH syr 100ml (Maan Pharma) | $ 0.57 |
| ECODIL-DH syr 50ml (Maan Pharma) | $ 0.39 |
| Ecodil-DS (India) | |
| Ecodil-DS Paracetamol 250 mg, Dextromethorphan hydrobromide10 mg, Phenylephrinehydrochloride 5 mg, Chlorpheniramine maleate 2 mg. P-SYR / 50ml (Maan Pharma) | $ 0.38 |
| 50ml (Maan Pharma) | $ 0.38 |
| ECODIL-DS P- syr 50ml (Maan Pharma) | $ 0.38 |
| Edomox-B (India) | |
| Edomox-B Amoxycillin 250 mg, Bromhexine8 mg, Lactobacillus sporogenes60. CAP / 10 | $ 0.43 |
| 10's | $ 0.43 |
| Efelin-X (India) | |
| Efelin-X Terbutaline 2.5 mg, Bromhexine8 mg. TAB / 10 | $ 0.12 |
| 10's | $ 0.12 |
| Eifcof-B (Thailand) | |
| Eifcof-B 15 mg x 1000's | |
| Eifcof-G (Thailand) | |
| Eifcof-G 15 mg x 50 x 10's (Bangkok Lab & Cosmetic) | |
| Eifcof-G 15 mg x 1, 000's (Bangkok Lab & Cosmetic) | |
| Eifcof-G tab 15 mg 1000's (Bangkok Lab & Cosmetic) | |
| Eifcof-G tab 15 mg 50 x 10's (Bangkok Lab & Cosmetic) | |
| Ekxine (Hong Kong) | |
| Ekxine 8 mg x 1 Bottle 100 Tablet (Strand) | |
| Ekxine 8 mg x 1, 000's (Strand) | |
| Eledyl (India) | |
| Eledyl Terbutaline sulphate 1.25 mg, Bromhexine hydrochloride 4 mg, Guaiphenesin 50 mg. EXP / 100ml | $ 0.34 |
| 100ml | $ 0.34 |
See 3651 substitutes for Drydex | |
References
- DailyMed. "DEXTROMETHORPHAN HYDROBROMIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "AMMONIUM CHLORIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "dextromethorphan". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Drydex are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Drydex. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yet3 consumers reported age
| Users | % | ||
|---|---|---|---|
| 30-45 | 2 | 66.7% | |
| 16-29 | 1 | 33.3% | |
Consumer reviews
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Information checked by Dr. Sachin Kumar, MD Pharmacology
