What is Eslo?
Eslo is used alone or together with other medicines to lower hypertension (high blood pressure) in adults and children. High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure can reduce the risk of strokes and heart attacks.
Eslo is a calcium channel blocker. It affects the movement of calcium into the cells of the heart and blood vessels. This relaxes the blood vessels and lowers blood pressure. A lower blood pressure will increase the supply of blood and oxygen to the heart.
Eslo is available only with your doctor's prescription.
Eslo indications
Hypertension
Eslo is indicated for the treatment of hypertension in adults and patients 6 years and older, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including Eslo.
Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than one drug to achieve blood pressure goals. For specific advice on goals and management, see published guidelines, such as those of the National High Blood Pressure Education Program’s Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC).
Numerous antihypertensive drugs, from a variety of pharmacologic classes and with different mechanisms of action, have been shown in randomized controlled trials to reduce cardiovascular morbidity and mortality, and it can be concluded that it is blood pressure reduction, and not some other pharmacologic property of the drugs, that is largely responsible for those benefits. The largest and most consistent cardiovascular outcome benefit has been a reduction in the risk of stroke, but reductions in myocardial infarction and cardiovascular mortality also have been seen regularly.
Elevated systolic or diastolic pressure causes increased cardiovascular risk, and the absolute risk increase per mmHg is greater at higher blood pressures, so that even modest reductions of severe hypertension can provide substantial benefit. Relative risk reduction from blood pressure reduction is similar across populations with varying absolute risk, so the absolute benefit is greater in patients who are at higher risk independent of their hypertension (for example, patients with diabetes or hyperlipidemia), and such patients would be expected to benefit from more aggressive treatment to lower blood pressure goal.
Some antihypertensive drugs have smaller blood pressure effects (as monotherapy) in black patients, and many antihypertensive drugs have additional approved indications and effects (e.g., on angina, heart failure, or diabetic kidney disease). These considerations may guide selection of therapy.
Eslo may be used alone or in combination with other antihypertensive agents.
Uses of Eslo in details
Use: Labeled Indications
Hypertension: Treatment of hypertension, alone or in combination with other antihypertensive agents, in adults and pediatric patients ≥6 years of age.
Eslo description
Eslo (INN), also known as levoamlodipine or Eslo is a pharmacologically active enantiomer of Eslo. Eslo belongs to the dihydropyridine group of calcium channel blocker used as an antihypertensive and antianginal agent. Eslo is currently marketed in Russia and India.
Eslo dosage
Eslo Dosage
Generic name: Eslo MALEATE 1.25mg in 1.25mg
Dosage form: tablet
Medically reviewed by Drugs.com. Last updated on Feb 14, 2020.
Adults
The usual initial antihypertensive oral dose of Eslo is 2.5 mg once daily, and the maximum dose is 5 mg once daily.
Small, fragile, or elderly patients, or patients with hepatic insufficiency may be started on 1.25 mg once daily and this dose may be used when adding Eslo to other antihypertensive therapy.
Adjust dosage according to blood pressure goals. In general, wait 7 to 14 days between titration steps. Titrate more rapidly, however, if clinically warranted, provided the patient is assessed frequently.
Children
The effective antihypertensive oral dose in pediatric patients ages 6–17 years is 1.25 mg to 2.5 mg once daily. Doses in excess of 2.5 mg daily have not been studied in pediatric patients.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical Disclaimer
More about Eslo (Eslo)
- Side Effects
- During Pregnancy
- Imprints, Shape & Color Data
- Drug Interactions
- Drug class: calcium channel blocking agents
- FDA Approval History
Professional resources
- Eslo (FDA)
Related treatment guides
- High Blood Pressure
Eslo interactions
See also:
What other drugs will affect Eslo?
May lead to false-negative aldosterone/renin ratio (Funder 2016).
Eslo side effects
See also:
What are the possible side effects of Eslo?
Adverse Reactions
All adverse reactions were reported with Eslo, as Eslo is the pharmacologically active isomer of Eslo.
>10%: Cardiovascular: Edema (2% to 11%)
1% to 10%:
Cardiovascular: Palpitations (1% to 5%), flushing (≤3%)
Central nervous system: Fatigue (5%), dizziness (3%), drowsiness (1%)
Gastrointestinal: Nausea (3%), abdominal pain (2%)
<1%: Abnormal dreams, angioedema, anorexia, anxiety, arthralgia, arthropathy, asthenia, atrial fibrillation, back pain, bradycardia, cardiac arrhythmia, chest pain, conjunctivitis, constipation, depersonalization, depression, diaphoresis, diarrhea, diplopia, dysphagia, dyspnea, epistaxis, erythema multiforme, erythematous rash, eye pain, female sexual disorder, flatulence, gingival hyperplasia, hot flash, hyperglycemia, hypersensitivity reaction, hypoesthesia, increased thirst, insomnia, leukopenia, maculopapular rash, malaise, male sexual disorder, muscle cramps, myalgia, nervousness, nocturia, pain, pancreatitis, paresthesia, peripheral ischemia, peripheral neuropathy, pruritus, purpuric disease, rigors, skin rash, syncope, tachycardia, thrombocytopenia, tinnitus, tremor, urinary frequency, urination disorder, vasculitis, ventricular tachycardia, vertigo, visual disturbance, vomiting, weight gain, weight loss, xerostomia
Frequency not defined: Cardiovascular: Peripheral edema
Postmarketing: Extrapyramidal reaction, gynecomastia, increased liver enzymes, jaundice
Eslo contraindications
Eslo is contraindicated in patients with known sensitivity to Eslo.
Active ingredient matches for Eslo:
Levamlodipine in India.
S-amlodipine in India.
| Unit description / dosage (Manufacturer) | Price, USD |
| ESLO Capsule/ Tablet / 2.5mg / 10 units (Emcure Pharmaceuticals) | $ 0.34 |
| ESLO Capsule/ Tablet / 1.25mg / 10 units (Emcure Pharmaceuticals) | $ 0.23 |
| ESLO Capsule/ Tablet / 5mg / 10 units (Emcure Pharmaceuticals) | $ 0.49 |
| Eslo 1.25mg TAB / 10 | $ 0.30 |
| Eslo 2.5mg TAB / 10 | $ 0.34 |
| Eslo 5mg TAB / 10 | $ 0.70 |
| 1.25 mg x 10's | $ 0.30 |
| 2.5 mg x 10's | $ 0.34 |
| 5 mg x 10's | $ 0.59 |
| ESLO 1.25MG TABLET 1 strip / 15 tablets each (Zuventus Healthcare Ltd) | $ 0.52 |
| ESLO 2.5 MG TABLET 1 strip / 15 tablets each (Zuventus Healthcare Ltd) | $ 0.83 |
| ESLO 5 MG TABLET 1 strip / 15 tablets each (Zuventus Healthcare Ltd) | $ 1.42 |
| ESLO tab 1.25 mg x 10's (Zuventus) | $ 0.33 |
| ESLO tab 2.5 mg x 10's (Zuventus) | $ 0.55 |
| ESLO tab 5 mg x 10's (Zuventus) | $ 0.94 |
| Eslo 1.25mg TAB / 10 | $ 0.30 |
| Eslo 2.5mg TAB / 10 | $ 0.34 |
| Eslo 5mg TAB / 10 | $ 0.70 |
| Eslo 1.25mg Tablet (Zuventus Healthcare Ltd) | $ 0.03 |
| Eslo 2.5mg Tablet (Zuventus Healthcare Ltd) | $ 0.06 |
| Eslo 5mg Tablet (Zuventus Healthcare Ltd) | $ 0.10 |
List of Eslo substitutes (brand and generic names): | |
| ESDIL (India) | |
| Esdil NA Tablet (Medley) | $ 0.02 |
| Eslo- AT | |
| Eslo- AT Amlodipine 5mg, Atenolol50mg TAB / 10 | $ 0.92 |
| Eslo- AT Atenolol 50mg, AmlodipineBestylate 2.5mg TAB / 10 | $ 0.60 |
| Eslo- Ril | |
| Eslo- Ril - Amlodipine Bestylate2.5mg, Ramipril 2.5mg TAB / 10 | $ 0.92 |
| Eslo-RIL (India) | |
| Eslo-RIL S-amlodipine besylate 2.5 mg, Ramipril 2.5 mg. TAB / 10 (Zuventus) | $ 0.92 |
| 10's (Zuventus) | $ 0.92 |
| Eslo-Ril - Amlodipine Bestylate2.5mg, Ramipril 2.5mg TAB / 10 (Zuventus) | $ 0.92 |
| ESLO-RIL tab 10's (Zuventus) | $ 0.92 |
| Eslo-Ril - Amlodipine Bestylate2.5mg, Ramipril 2.5mg TAB / 10 (Zuventus) | $ 0.92 |
| Espin- AT | |
| Espin- AT - TAB / 10 | $ 0.12 |
| Espin- LT | |
| Espin- LT - TAB / 10 | $ 0.87 |
| Espin-AT (India) | |
| Espin-AT S-amlodipine 2.5 mg, Atenolol50 mg. TAB / 10 (Intas) | $ 0.12 |
| Espin-AT S-amlodipine 2.5 mg, Atenolol50 mg TAB / 10 (Intas) | $ 0.12 |
| 10's (Intas) | $ 0.12 |
| ESPIN-AT 50 MG/2.5 MG TABLET 1 strip / 10 tablets each (Intas) | $ 0.52 |
| ESPIN-AT tab 10's (Intas) | $ 0.12 |
| Espin-LT (India) | |
| Espin-LT S-amlodipine 2.5 mg, Losartan50 mg. TAB / 10 (Intas) | $ 0.87 |
| 10's (Intas) | $ 0.87 |
| ESPIN-LT 50 MG/2.5 MG TABLET 1 strip / 10 tablets each (Intas) | $ 1.31 |
| ESPIN-LT tab 10's (Intas) | $ 0.87 |
| Ethivask (Indonesia) | |
| Ethivask 5 mg x 3 x 10's | $ 7.44 |
| Ethivask 10 mg x 3 x 10's | |
| Eucoran (Colombia, Peru) | |
| Europine | |
| Europine 5mg TAB / 10 | |
| Evangio (Greece, Malta) | |
| Evasc (South Korea) | |
| EXLODEP | |
| EXLODEP 5MG TABLET 1 strip / 20 tablets each (Olcare (Excare)) | $ 0.33 |
| EXLODEP tab 5 mg x 10's (Olcare (Excare)) | $ 0.24 |
| Ezlopin (Philippines) | |
| Fabocef (Argentina) | |
| Fada Amlodipina (Argentina) | |
| Famodip (Vietnam) | |
| Famodip 5 mg x 1 Box | |
| Farlod (Pakistan) | |
| Finacal 10 (Peru) | |
| Finacal 5 (Peru) | |
| Finamlox (Poland) | |
| Finevask (Indonesia) | |
| Fixodip (Turkey) | |
| Flamodip (Vietnam) | |
| Flamodip 10 mg x 1 Box | |
| Fludexam (Austria) | |
| Fopin (Bosnia & Herzegowina, Serbia) | |
| Fuleqing (China) | |
See 4206 substitutes for Eslo | |
References
- PubChem. "amlodipine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "amlodipine". http://www.drugbank.ca/drugs/DB00381 (accessed September 17, 2018).
- MeSH. "Antihypertensive Agents". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Eslo are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Eslo. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yet1 consumer reported age
| Users | % | ||
|---|---|---|---|
| > 60 | 1 | 100.0% | |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
