HistadicВ® Uses

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What is HistadicВ®?

HistadicВ® is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

HistadicВ® is used to treat runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.

HistadicВ® may also be used for purposes not listed in this medication guide.

HistadicВ® indications

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Temporary relief of sneezing, itchy, watery eyes, itchy nose or throat, and runny nose caused by hay fever (allergic rhinitis), or other respiratory allergies.

How should I use HistadicВ®?

Use HistadicВ® as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use HistadicВ®.

Uses of HistadicВ® in details

This medication is used to treat itching and pain caused by minor burns/cuts/scrapes, sunburn, insect bites, minor skin irritations, or rashes from poison ivy, poison oak, or poison sumac.

Diphenhydramine belongs to a class of drugs known as antihistamines. It works by preventing the effects of a certain natural substance (histamine) that causes itching. Calamine helps to dry the oozing and weeping caused by irritation from poisonous plants.

Use of this medication is not recommended in children younger than 2 years unless directed by the doctor.

How to use HistadicВ® topical

Use this medication on the skin only. Some products may need to be shaken well before use. Follow all directions on the product package, or use as directed by your doctor. Before applying, clean the affected area with soap and water. Gently pat dry. Apply to the affected area as directed, usually 3 to 4 times a day. Wash hands immediately after use, unless the area being treated includes the hands.

Do not use on large areas of the body or apply more often than directed. Do not use on chickenpox or measles. Do not use with other products that contain diphenhydramine (e.g., allergy medication taken by mouth). Your condition will not clear faster, but side effects may be increased.

Avoid getting the product in your eyes, nose, ears, or mouth. If the medication gets in these areas, rinse the area right away with clean water.

Tell your doctor if your condition persists or worsens after 7 days of treatment. If you think you may have a serious medical problem, seek immediate medical attention.

HistadicВ® description

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An alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine. It has been used in the treatment of several disorders including asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. It has become less extensively used with the advent of more selective agonists.

HistadicВ® dosage

Tab Adult & childn >12 yr 1 tab tds-qds. Childn 6-12 yr ½ tab tds-qds. Syr Adult 5 mL tds-qds. Childn 6-12 yr 2.5 mL tds-qds, 2-5 yr 1.25 mL tds-qds.

HistadicВ® interactions

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What other drugs will affect HistadicВ®?

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), antispasmodics (e.g., atropine, belladonna alkaloids), drugs for Parkinson's disease (e.g., anticholinergics such as benztropine, trihexyphenidyl), scopolamine, tricyclic antidepressants (e.g., amitriptyline).

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, amitriptyline, trazodone). Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products.

HistadicВ® is very similar to dexchlorpheniramine. Do not use medications containing dexchlorpheniramine while using HistadicВ®.

This medication may interfere with certain laboratory tests (including allergy skin testing), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

HistadicВ® side effects

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What are the possible side effects of HistadicВ®?

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Mild stinging, redness, swelling, or dry/flaky skin may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

HistadicВ® contraindications

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What is the most important information I should know about HistadicВ®?

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Hypersensitivity to antihistamines; narrow-angle glaucoma; stenosing peptic ulcer; symptomatic prostatic hypertrophy; asthmatic attack; bladder neck obstruction; pyloroduodenal obstruction; MAO therapy; use in newborn or premature infants and in breast-feeding mothers.

Active ingredient matches for HistadicВ®:

Chlorpheniramine Maleate


List of HistadicВ® substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Histarine 50 ml Syrup (Kentreck Labs Pvt Ltd.)$ 0.03
HISTARINE 1MG/125MG/2.5MG SYRUP 1 bottle / 50 ML syrup each (Kentreck Labs Pvt Ltd.)$ 0.60
Histarine 1 mg/125 mg/2.5 mg Syrup (Kentreck Labs Pvt Ltd.)$ 0.60
Histatab/Histatapp 4 mg x 100's
Histatab/Histatapp 4 mg x 1, 000's
Histatab/Histatapp 2 g/5 mL x 60 mL
Histatab/Histatapp 2 g/5 mL x 1 gal
Histomonic 650+25+4 Tablet (Beckcem Drugs International (P) Ltd)$ 0.02
Histomonic Plus 60 ml Syrup (Beckcem Drugs International (P) Ltd)$ 0.03
I Tus 100 ml Syrup (Shrine Remedies)$ 0.03
10ml (Ind-Swift)$ 0.17
I-TOP eye drops 10ml (Ind-Swift)$ 0.17
Indikof C 100 ml Syrup (Alkem Laboratories Ltd)$ 0.03
INDIKOF C SYRUP 1 bottle / 100 ML syrup each (Alkem Laboratories Ltd)$ 0.74
Indikof C Syrup (Alkem Laboratories Ltd)$ 0.74
Inlid Total Tablet (Donnel Healthcare Pvt Ltd)$ 0.02
Jadyl 100 ml Expectorant (Smilax Pharmaceuticals)$ 0.02
Jest 60 ml Expectorant (Acron Pharmaceuticals)$ 0.02
Johncidin
Kangsau 120 mL
Kanmau
Kanmo
Kavrex 100 ml Syrup (Kavya Healthcare)$ 0.04
Keto PC Eye 10 ml Drop (Laborate Pharmaceuticals India Ltd.)$ 0.53
Kildep Tablet (Healing Touch Pharmaceuticals)$ 0.02
Kobamin
Kodekof 60 ml Syrup (Finecure Pharmaceuticals Ltd)$ 0.03
Koder-G 1 mL
100ml (Meridian Medicare Ltd.)$ 0.35
Kofrid 100 ml Syrup (Meridian Medicare Ltd.)$ 0.02
Kofrid 10+5 Tablet (Meridian Medicare Ltd.)$ 0.03
KOFRID 2.5MG/30MG/55MG EXPECTORANT 1 bottle / 100 ML expectorant each (Meridian Medicare Ltd.)$ 0.78
KOFRID syr 100ml (Meridian Medicare Ltd.)$ 0.35
Kofrid 2.5 mg/30 mg/55 mg Expectorant (Meridian Medicare Ltd.)$ 0.01
Kopin$ Daw Jih
Kopin / Mey See 1 mL
Kopin / Mey See 60 mL
Kufcol D Tablet (Rockstar Pharma (group of Athens Labs))$ 0.04
100ml (ModHike)$ 0.46
LIGHT-CUF syr 100ml (ModHike)$ 0.46

References

  1. DailyMed. "CHLORPHENIRAMINE POLISTIREX; HYDROCODONE POLISTIREX: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "chlorpheniramine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "chlorpheniramine". http://www.drugbank.ca/drugs/DB01114 (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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