Kofrid Uses

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What is Kofrid?

Kofrid is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Kofrid is used to treat runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.

Kofrid may also be used for purposes not listed in this medication guide.

Kofrid indications

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Temporary relief of sneezing, itchy, watery eyes, itchy nose or throat, and runny nose caused by hay fever (allergic rhinitis), or other respiratory allergies.

How should I use Kofrid?

Use Kofrid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Kofrid.

Uses of Kofrid in details

This medication is used to treat itching and pain caused by minor burns/cuts/scrapes, sunburn, insect bites, minor skin irritations, or rashes from poison ivy, poison oak, or poison sumac.

Diphenhydramine belongs to a class of drugs known as antihistamines. It works by preventing the effects of a certain natural substance (histamine) that causes itching. Calamine helps to dry the oozing and weeping caused by irritation from poisonous plants.

Use of this medication is not recommended in children younger than 2 years unless directed by the doctor.

How to use Kofrid topical

Use this medication on the skin only. Some products may need to be shaken well before use. Follow all directions on the product package, or use as directed by your doctor. Before applying, clean the affected area with soap and water. Gently pat dry. Apply to the affected area as directed, usually 3 to 4 times a day. Wash hands immediately after use, unless the area being treated includes the hands.

Do not use on large areas of the body or apply more often than directed. Do not use on chickenpox or measles. Do not use with other products that contain diphenhydramine (e.g., allergy medication taken by mouth). Your condition will not clear faster, but side effects may be increased.

Avoid getting the product in your eyes, nose, ears, or mouth. If the medication gets in these areas, rinse the area right away with clean water.

Tell your doctor if your condition persists or worsens after 7 days of treatment. If you think you may have a serious medical problem, seek immediate medical attention.

Kofrid description

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An alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine. It has been used in the treatment of several disorders including asthma, heart failure, rhinitis, and urinary incontinence, and for its central nervous system stimulatory effects in the treatment of narcolepsy and depression. It has become less extensively used with the advent of more selective agonists.

Kofrid dosage

Tab Adult & childn >12 yr 1 tab tds-qds. Childn 6-12 yr ½ tab tds-qds. Syr Adult 5 mL tds-qds. Childn 6-12 yr 2.5 mL tds-qds, 2-5 yr 1.25 mL tds-qds.

Kofrid interactions

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What other drugs will affect Kofrid?

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), antispasmodics (e.g., atropine, belladonna alkaloids), drugs for Parkinson's disease (e.g., anticholinergics such as benztropine, trihexyphenidyl), scopolamine, tricyclic antidepressants (e.g., amitriptyline).

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, amitriptyline, trazodone). Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products.

Kofrid is very similar to dexchlorpheniramine. Do not use medications containing dexchlorpheniramine while using Kofrid.

This medication may interfere with certain laboratory tests (including allergy skin testing), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Kofrid side effects

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What are the possible side effects of Kofrid?

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Mild stinging, redness, swelling, or dry/flaky skin may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Kofrid contraindications

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What is the most important information I should know about Kofrid?

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Hypersensitivity to antihistamines; narrow-angle glaucoma; stenosing peptic ulcer; symptomatic prostatic hypertrophy; asthmatic attack; bladder neck obstruction; pyloroduodenal obstruction; MAO therapy; use in newborn or premature infants and in breast-feeding mothers.

Active ingredient matches for Kofrid:

Chlorpheniramine maleate in India.

Ammonium Chloride/Chlorpheniramine/Sodium Citrate

Ammonium chloride/menthol/sodium citrate in India.


Unit description / dosage (Manufacturer)Price, USD
100ml$ 0.35
Kofrid 100 ml Syrup$ 0.02
Kofrid 10+5 Tablet$ 0.03
KOFRID 2.5MG/30MG/55MG EXPECTORANT 1 bottle / 100 ML expectorant each (Numed)$ 0.78
KOFRID syr 100ml (Meridian)$ 0.35
Kofrid 2.5 mg/30 mg/55 mg Expectorant (Numed)$ 0.01

List of Kofrid substitutes (brand and generic names):

Koder-G 1 mL
Kopin$ Daw Jih
Kopin / Mey See 1 mL
Kopin / Mey See 60 mL
Kufcol D Tablet (Rockstar Pharma (group of Athens Labs))$ 0.04
100ml (ModHike)$ 0.46
LIGHT-CUF syr 100ml (ModHike)$ 0.46
Nacold 60 ml Syrup (Biotech Limited)$ 0.02
Nacold 500+20+10 Tablet (Biotech Limited)$ 0.02
Nacold 500+25+2 Tablet (Biotech Limited)$ 0.01
Naifa Eye 5 ml Drop (Mmatrics Pharmaceuticals.)$ 0.46
Neo Husten 2 mL
Neo-Vinapyrin 2 mL
Neodril 100 ml Syrup (Healing Touch Pharmaceuticals)$ 0.01
New Genkof 100 ml Syrup (Health Guard (India) Pvt. Ltd.)$ 0.04
No Cold Tablet (Alka Pharmaceuticals)$ 0.02
100ml$ 0.30
NOMOKOF EXPECTORANT 1 bottle / 100 ML expectorant each (Cadila)$ 0.55
Nomokoof 100 ml Syrup (Cadila Pharmaceuticals Ltd.)$ 0.02
Non-Pyrin
Nonanticold
Norvent D 100 ml Syrup (Ind-Chemie Health Specialities Pvt Ltd.)$ 0.03
NORVENT D 4MG/10MG SYRUP 1 bottle / 100 ML syrup each (Ind-Chemie Health Specialities Pvt Ltd.)$ 0.98
Norvent D Syrup (Ind-Chemie Health Specialities Pvt Ltd.)$ 1.08
Noscaphene 10+10+4 Tablet (Medoz Pharmaceuticals)$ 0.02
Nosthyl 100 ml Syrup (Biochem Pharmaceutical Industrial Ltd)$ 0.02
Nosthyl 7.5+7.5+2.5 Tablet (Biochem Pharmaceutical Industrial Ltd)$ 0.04
Notril Plus 60 ml Syrup (Winsome Laboratories Ltd.)$ 0.03
NOTRIL PLUS SYRUP 1 bottle / 60 ML syrup each (Winsome Laboratories Ltd.)$ 0.37
NOTRIL PLUS syr 60ml (Winsome Laboratories Ltd.)$ 0.46
Notril Plus Syrup (Winsome Laboratories Ltd.)$ 0.37
Novacet Plus 60 ml Syrup (Pharmanova India Drugs (P) Ltd)$ 0.03
NP Cold 60 ml Suspension (NPS Pharmaceuticals)$ 0.03
Ntkuf D 100 ml Syrup (Hauz Pharma Pvt Ltd)$ 0.03
Nutussic 60 ml Syrup (Wander Ltd)$ 0.04
NUTUSSIC SYRUP 1 bottle / 60 ML syrup each (Wander Ltd)$ 0.38
Nutussic Syrup (Wander Ltd)$ 0.38
Oballercal 5 mL
Ocucel A Eye 10 ml Drop (Proxima (FDC Limited))$ 0.04
OCUCEL A EYE DROP 1 packet / 10 ML eye drop each (Proxima (FDC Limited))$ 0.48

References

  1. DailyMed. "CHLORPHENIRAMINE POLISTIREX; HYDROCODONE POLISTIREX: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "SODIUM CITRATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. DailyMed. "AMMONIUM CHLORIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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