What is Itrazol?
Itrazol is used to treat serious fungal or yeast infections. Itrazol oral solution is only used to treat oropharyngeal or esophageal candidiasis (thrush, oral thrush). Itrazol capsule is used to treat fungal infections, such as aspergillosis (fungal infection in the lungs), blastomycosis (Gilchrist’s disease), histoplasmosis (Darling’s disease), or onychomycosis (fungal infection in the fingernails or toenails). Itrazol tablet is only used to treat onychomycosis of the toenails. Itrazol works by killing the fungus or yeast and preventing its growth.
Itrazol is available only with your doctor's prescription.
Itrazol indications
Itrazol® (Itrazol) Injection/Oral Solution is indicated for empiric therapy of febrile neutropenic patients with suspected fungal infections. (NOTE: In a comparative trial, the overall response rate for Itrazol-treated subjects was higher than for amphotericin B-treated subjects. However, compared to amphotericin B-treated subjects, a larger number of Itrazol-treated subjects discontinued treatment due to persistent fever and a change in antifungal medication due to fever. Whereas, a larger number of amphotericin B-treated subjects discontinued due to drug intolerance.
Itrazol® (Itrazol) Injection is also indicated for the treatment of the following fungal infections in immunocompromised and non-immunocompromised patients:
- Blastomycosis, pulmonary and extrapulmonary;
- Histoplasmosis, including chronic cavitary pulmonary disease and disseminated, non-meningeal histoplasmosis; and
- Aspergillosis, pulmonary and extrapulmonary, in patients who are intolerant of or who are refractory to amphotericin B therapy.
Specimens for fungal cultures and other relevant laboratory studies (wet mount, histopathology, serology) should be obtained prior to therapy to isolate and identify causative organisms. Therapy may be instituted before the results of the cultures and other laboratory studies are known; however, once these results become available, anti-infective therapy should be adjusted accordingly.
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How should I use Itrazol?
Use Itrazol tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Itrazol tablets. Talk to your pharmacist if you have questions about this information.
- Take Itrazol tablets with a full meal. If you have low stomach acid or you take medicine to reduce stomach acid, take Itrazol tablets with an acidic beverage (eg, non-diet cola).
- If you take antacids, didanosine, H blockers (eg, famotidine), or proton pump inhibitors (PPIs) (eg, omeprazole), ask your doctor or pharmacist how to take it with Itrazol tablets.
- To clear up your infection completely, take Itrazol tablets for the full course of treatment. Keep taking it even if you feel better in a few days. Do not miss any doses.
- Itrazol tablets works best if it is taken at the same time each day.
- If you miss a dose of Itrazol tablets, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Itrazol tablets.
Uses of Itrazol in details
Use: Labeled Indications
Aspergillosis (capsules): Treatment of pulmonary and extrapulmonary aspergillosis in immunocompromised and nonimmunocompromised patients who are intolerant of or refractory to amphotericin B therapy. Note: IDSA Aspergillosis guidelines recommend amphotericin B formulations for invasive aspergillosis (initial or salvage) only when voriconazole is contraindicated or not tolerated (IDSA [Patterson 2016]).
Blastomycosis (capsules): Treatment of pulmonary and extrapulmonary blastomycosis in immunocompromised and nonimmunocompromised patients.
Histoplasmosis (capsules): Treatment of histoplasmosis, including chronic cavitary pulmonary disease and disseminated, nonmeningeal histoplasmosis in immunocompromised and nonimmunocompromised patients.
Onychomycosis:
Capsules (100 mg [Itrazol]): Treatment of onychomycosis of the toenail, with or without fingernail involvement, and onychomycosis of the fingernail caused by dermatophytes (tinea unguium) in nonimmunocompromised patients
Tablets: Treatment of onychomycosis of the toenail caused by Trichophyton rubrum or Trichophyton mentagrophytes in nonimmunocompromised patients
Oropharyngeal/Esophageal candidiasis (oral solution): Treatment of oropharyngeal and esophageal candidiasis
Canadian labeling: Oral capsules: Additional indications (not in US labeling):
Candidiasis, oral and/or esophageal: Treatment of oral and/or esophageal candidiasis in immunocompromised and immunocompetent patients
Chromomycosis: Treatment of chromomycosis in immunocompromised and immunocompetent patients
Dermatomycoses: Treatment of dermatomycoses due to tinea pedis, tinea cruris, tinea corporis, and of pityriasis versicolor in patients for whom oral therapy is appropriate
Onychomycosis: Treatment of onychomycosis in immunocompromised and immunocompetent patients
Paracoccidioidomycosis: Treatment of paracoccidioidomycosis in immunocompromised and immunocompetent patients
Sporotrichosis: Treatment of cutaneous and lymphatic sporotrichosis in immunocompromised and immunocompetent patients
Off Label Uses
Candidiasis, vulvovaginal in HIV-infected patients
Based on the US Department of Health and Human Services (HHS) Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents, Itrazol oral solution is an effective and recommended alternative agent in the management of vulvovaginal candidiasis in HIV-infected patients.
Coccidioidal meningitis in HIV-infected patients
Based on the US Department of Health and Human Services (HHS) Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents, Itrazol is an effective and recommended alternative agent in the treatment of and as chronic suppressive therapy of coccidioidal meningitis in HIV-infected patients.
Coccidioidal pneumonia in HIV-infected patients
Based on the US Department of Health and Human Services (HHS) Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents, Itrazol is an effective and recommended agent in the treatment of coccidioidal pneumonia (focal pneumonia) in HIV-infected patients.
Coccidioidomycosis (non-HIV infected)
Based on the Infectious Diseases Society of America (IDSA) guidelines for the treatment of coccidioidomycosis, Itrazol is an effective and recommended agent for the treatment of coccidioidomycosis, including coccidioidal meningitis and certain types of pulmonary and extrapulmonary infections.
Cryptococcosis in HIV-infected patients
Based on the HHS Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents, Itrazol is an effective and recommended alternative agent in the treatment (consolidation therapy) of cryptococcal meningitis in HIV-infected patients.
Microsporidiosis, disseminated in HIV-infected patients
Based on the US Department of Health and Human Services (HHS) Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents, Itrazol is an effective and recommended agent in the management of disseminated microsporidiosis caused by Trachipleistophora or Anncaliia in HIV-infected patients.
Penicilliosis in HIV-infected patients
Based on the US Department of Health and Human Services (HHS) Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents, Itrazol is an effective and recommended agent in the treatment or primary prophylaxis of penicilliosis in HIV-infected patients.
Itrazol description
Each capsule contains Itraconazole 100 mg in a pellet formulation for oral administration. The inactive ingredients are sucrose, corn starch, hydrolysed starch syrup, hypromellose and macrogol. The capsule itself contains titanium dioxide, indigotindisulfonate sodium, coccine nouvelle and gelatin.
Itrazol oral solution also contains hydroxypropyl β-cyclodextrin, sorbitol, propylene glycol, hydrochloric acid, cherry flavour 1, cherry flavour 2, caramel flavour, sodium saccharin, sodium hydroxide and purified water.
Itrazol dosage
Itrazol Dosage
Generic name: Itrazol 200mg
Dosage form: tablet
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Itrazol should be taken with a full meal at the same time each day. The recommended dose is 200 mg (one tablet) once daily for 12 consecutive weeks.
Use in Patients with Renal Impairment:
Limited data are available on the use of oral Itrazol in patients with renal impairment. Caution should be exercised when Itrazol is administered to patients with renal impairment.
Use in Patients with Hepatic Impairment:
Limited data are available on the use of oral Itrazol in patients with hepatic impairment. Caution should be exercised when Itrazol is administered to patients with hepatic impairment.
More about Itrazol (Itrazol)
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Consumer resources
- Itrazol
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- Other brands: Itrazol, Itrazol PulsePak
Professional resources
- Itrazol (FDA)
- Itrazol (AHFS Monograph)
Related treatment guides
- Candidemia
- Aspergillosis, Aspergilloma
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- Blastomycosis
- Candida Urinary Tract Infection
- More (18) »
Itrazol interactions
See also:
What other drugs will affect Itrazol?
Itrazol and its major metabolite, hydroxyitraconazole, are inhibitors of CYP3A4. Therefore, the following drug interactions may occur :
- Itrazol® (Itrazol injection) may decrease the elimination of drugs metabolized by CYP3A4, resulting in increased plasma concentrations of these drugs when they are administered with Itrazol® (Itrazol injection). These elevated plasma concentrations may increase or prolong both therapeutic and adverse effects of these drugs. Whenever possible, plasma concentrations of these drugs should be monitored, and dosage adjustments made after concomitant Itrazol® (Itrazol injection) therapy is initiated. When appropriate, clinical monitoring for signs or symptoms of increased or prolonged pharmacologic effects is advised. Upon discontinuation, depending on the dose and duration of treatment, Itrazol plasma concentrations decline gradually (especially in patients with hepatic cirrhosis or in those receiving CYP3A4 inhibitors). This is particularly important when initiating therapy with drugs whose metabolism is affected by Itrazol.
- Inducers of CYP3A4 may decrease the plasma concentrations of Itrazol. Itrazol® (Itrazol injection) may not be effective in patients concomitantly taking Itrazol® (Itrazol injection) and one of these drugs. Therefore, administration of these drugs with Itrazol® (Itrazol injection) is not recommended.
- Other inhibitors of CYP3A4 may increase the plasma concentrations of Itrazol. Patients who must take Itrazol® (Itrazol injection) concomitantly with one of these drugs should be monitored closely for signs or symptoms of increased or prolonged pharmacologic effects of Itrazol® (Itrazol injection).
Table 1: Selected Drugs that are Predicted to Alter the Plasma Concentration of Itrazol or Have Their Plasma Concentration Altered by Itrazol® (Itrazol injection) For information on parenterally administered midazolam, see the Benzodiazepine paragraph below.
Antiarrhythmics
The class IA antiarrhythmic quinidine and class III antiarrhythmic dofetilide are known to prolong the QT interval. Coadministration of quinidine or dofetilide with Itrazol® (Itrazol injection) may increase plasma concentrations of quinidine or dofetilide which could result in serious cardiovascular events. Therefore, concomitant administration of Itrazol® (Itrazol injection) and quinidine or dofetilide is contraindicated.
The class IA antiarrhythmic disopyramide has the potential to increase the QT interval at high plasma concentrations. Caution is advised when Itrazol® (Itrazol injection) and disopyramide are administered concomitantly.
Concomitant administration of digoxin and Itrazol® (Itrazol injection) has led to increased plasma concentrations of digoxin via inhibition of P-glycoprotein.
Anticonvulsants
Reduced plasma concentrations of Itrazol were reported when Itrazol® (Itrazol injection) was administered concomitantly with phenytoin. Carbamazepine, phenobarbital, and phenytoin are all inducers of CYP3A4. Although interactions with carbamazepine and phenobarbital have not been studied, concomitant administration of Itrazol® (Itrazol injection) and these drugs would be expected to result in decreased plasma concentrations of Itrazol. In addition, in vivo studies have demonstrated an increase in plasma carbamazepine concentrations in subjects concomitantly receiving ketoconazole. Although there are no data regarding the effect of Itrazol on carbamazepine metabolism, because of the similarities between ketoconazole and Itrazol, concomitant administration of Itrazol® (Itrazol injection) and carbamazepine may inhibit the metabolism of carbamazepine.
Antimycobacterials
Drug interaction studies have demonstrated that plasma concentrations of azole antifungal agents and their metabolites, including Itrazol and hydroxyitraconazole, were significantly decreased when these agents were given concomitantly with rifabutin or rifampin. In vivo data suggest that rifabutin is metabolized in part by CYP3A4. Itrazol® (Itrazol injection) may inhibit the metabolism of rifabutin. Although no formal study data are available for isoniazid, similar effects should be anticipated. Therefore, the efficacy of Itrazol® (Itrazol injection) could be substantially reduced if given concomitantly with one of these agents. Coadministration is not recommended.
Antineoplastics
Itrazol® (Itrazol injection) may inhibit the metabolism of busulfan, docetaxel, and vinca alkaloids.
Antipsychotics
Pimozide is known to prolong the QT interval and is partially metabolized by CYP3A4. Coadministration of pimozide with Itrazol® (Itrazol injection) could result in serious cardiovascular events. Therefore, concomitant administration of Itrazol® (Itrazol injection) and pimozide is contraindicated.
Benzodiazepines
Concomitant administration of Itrazol® (Itrazol injection) and alprazolam, diazepam, oral midazolam, or triazolam could lead to increased plasma concentrations of these benzodiazepines. Increased plasma concentrations could potentiate and prolong hypnotic and sedative effects. Concomitant administration of Itrazol® (Itrazol injection) and oral midazolam or triazolam is contraindicated. If midazolam is administered parenterally, special precaution and patient monitoring is required since the sedative effect may be prolonged.
Calcium Channel Blockers
Edema has been reported in patients concomitantly receiving Itrazol® (Itrazol injection) and dihydropyridine calcium channel blockers. Appropriate dosage adjustment may be necessary.
Calcium channel blockers can have a negative inotropic effect which may be additive to those of Itrazol; Itrazol can inhibit the metabolism of calcium channel blockers such as dihydropyridines (e.g., nifedipine and felodipine) and verapamil. Therefore, caution should be used when co-administering Itrazol and calcium channel blockers due to an increased risk of CHF. Concomitant administration of Itrazol® (Itrazol injection) and nisoldipine results in clinically significant increases in nisoldipine plasma concentrations which cannot be managed by dosage reduction, therefore the concomitant administration of Itrazol® (Itrazol injection) and nisoldipine is contraindicated.
Gastrointestinal Motility Agents
Coadministration of Itrazol® (Itrazol injection) with cisapride can elevate plasma cisapride concentrations which could result in serious cardiovascular events. Therefore, concomitant administration of Itrazol® (Itrazol injection) with cisapride is contraindicated.
HMG CoA-Reductase Inhibitors
Human pharmacokinetic data suggest that Itrazol® (Itrazol injection) inhibits the metabolism of atorvastatin, cerivastatin, lovastatin, and simvastatin, which may increase the risk of skeletal muscle toxicity, including rhabdomyolysis. Concomitant administration of Itrazol® (Itrazol injection) with HMG CoA-reductase inhibitors, such as lovastatin and simvastatin, is contraindicated.
Immunosuppressants
Concomitant administration of Itrazol® (Itrazol injection) and cyclosporine or tacrolimus has led to increased plasma concentrations of these immunosuppressants. Concomitant administration of Itrazol® (Itrazol injection) and sirolimus could increase plasma concentrations of sirolimus.
Macrolide Antibiotics
Erythromycin and clarithromycin are known inhibitors of CYP3A4 and may increase plasma concentrations of Itrazol. In a small pharmacokinetic study involving HIV infected patients, clarithromycin was shown to increase plasma concentrations of Itrazol. Similarly, following administration of 1 gram of erythromycin ethyl succinate and 200 mg Itrazol as single doses, the mean Cmax and AUC 0-∞ of Itrazol increased by 44% (90% CI: 119-175%) and 36% (90% CI: 108-171%), respectively.
Oral Hypoglycemic Agents
Severe hypoglycemia has been reported in patients concomitantly receiving azole antifungal agents and oral hypoglycemic agents. Blood glucose concentrations should be carefully monitored when Itrazol® (Itrazol injection) and oral hypoglycemic agents are coadministered.
Polyenes
Prior treatment with Itrazol, like other azoles, may reduce or inhibit the activity of polyenes such as amphotericin B. However, the clinical significance of this drug effect has not been clearly defined.
Protease Inhibitors
Concomitant administration of Itrazol® (Itrazol injection) and protease inhibitors metabolized by CYP3A4, such as indinavir, ritonavir, and saquinavir, may increase plasma concentrations of these protease inhibitors. In addition, concomitant administration of Itrazol® (Itrazol injection) and indinavir and ritonavir (but not saquinavir) may increase plasma concentrations of Itrazol. Caution is advised when Itrazol® (Itrazol injection) and protease inhibitors must be given concomitantly.
Reverse Transcriptase Inhibitors
Nevirapine is an inducer of CYP3A4. In vivo studies have shown that nevirapine induces the metabolism of ketoconazole, significantly reducing the bioavailability of ketoconazole. Studies involving nevirapine and Itrazol have not been conducted. However, because of the similarities between ketoconazole and Itrazol, concomitant administration of Itrazol® (Itrazol injection) and nevirapine is not recommended. In a clinical study, when 8 HIV-infected subjects were treated concomitantly with Itrazol® (Itrazol injection) Capsules 100 mg twice daily and the nucleoside reverse transcriptase inhibitor zidovudine 8 ± 0.4 mg/kg/day, the pharmacokinetics of zidovudine were not affected. Other nucleoside reverse transcriptase inhibitors have not been studied.
Other
- Levacetylmethadol (levomethadyl) is known to prolong the QT interval and is metabolized by CYP3A4. Co-administration of levacetylmethadol with Itrazol® (Itrazol injection) could result in serious cardiovascular events. Therefore, concomitant administration of Itrazol® (Itrazol injection) and levacetylmethadol is contraindicated.
- Elevated concentrations of ergot alkaloids can cause ergotism, ie. a risk for vasospasm potentially leading to cerebral ischemia and/or ischemia of the extremities. Concomitant administration of ergot alkaloids such as dihydroergotamine, ergometrine (ergonovine), ergotamine and methylergometrine (methylergonovine) with Itrazol® (Itrazol injection) is contraindicated.
- Halofantrine has the potential to prolong the QT interval at high plasma concentrations. Caution is advised when Itrazol® (Itrazol injection) and halofantrine are administered concomitantly.
- In vitro data suggest that alfentanil is metabolized by CYP3A4. Administration with Itrazol® (Itrazol injection) may increase plasma concentrations of alfentanil.
- Human pharmacokinetic data suggest that concomitant administration of Itrazol® (Itrazol injection) and buspirone results in significant increases in plasma concentrations of buspirone.
- Itrazol® (Itrazol injection) may inhibit the metabolism of certain glucocorticosteroids such as budesonide, dexamethasone, fluticasone and methylprednisolone.
- In vitro data suggest that trimetrexate is extensively metabolized by CYP3A4. In vitro animal models have demonstrated that ketoconazole potently inhibits the metabolism of trimetrexate. Although there are no data regarding the effect of Itrazol on trimetrexate metabolism, because of the similarities between ketoconazole and Itrazol, concomitant administration of Itrazol® (Itrazol injection) and trimetrexate may inhibit the metabolism of trimetrexate.
- Cilostazol and eletriptan are CYP3A4 metabolized drugs that should be used with caution when co-administered with Itrazol® (Itrazol injection).
- Itrazol® (Itrazol injection) enhances the anticoagulant effect of coumarin-like drugs, such as warfarin.
- Fentanyl plasma concentrations could be increased or prolonged by concomitant use of Itrazol® (Itrazol injection) and may cause potentially fatal respiratory depression.
Itrazol side effects
See also:
What are the possible side effects of Itrazol?
Interaction Potential: Itrazol oral solution has a potential for clinically important drug interactions. Clinical Trials: Table 1 shows the adverse events reported among patients in clinical trials (pooled data) of Itrazol oral solution compared to fluconazole, in the treatment of oropharyngeal and esopharyngeal candidosis. It includes all adverse events (with an incidence of ≥2%) reported among Itrazol-treated patients. About 44% of patients treated with Itrazol oral solution and about 43% of patients treated with fluconazole experienced at least one adverse event. The adverse events reported are summarized irresponsive of the causality assessment of the investigators.
Post-Marketing Experience: Adverse drug reactions from spontaneous reports during the worldwide post-marketing experience with Itrazol (all formulations) that meet threshold criteria are included in Table 2. The adverse drug reactions are ranked by frequency, using the following convention: Very common ≥1/10, common ≥1/100 and <1/10, uncommon ≥1/1000 and <1/100, rare ≥1/10,000 and <1/1000, very rare <1/10,000, including isolated reports.
The frequency in Table 2 reflect reporting rates for adverse drug reactions from spontaneous reports and do not represent more precise estimates of incidence that might be obtained in clinical or epidemiological studies.
Itrazol contraindications
See also:
What is the most important information I should know about Itrazol?
Drug Interactions
Concomitant administration of Itrazol® (Itrazol) Capsules, Injection, or
Oral Solution and certain drugs metabolized by the cytochrome P450 3A4 isoenzyme system (CYP3A4) may result in increased plasma concentrations of those drugs, leading to potentially serious and/or life-threatening adverse events. Cisapride, oral midazolam, nisoldipine, pimozide, quinidine, dofetilide, triazolam and levacetylmethadol (levomethadyl) are contraindicated with Itrazol® (Itrazol injection). HMG CoA-reductase inhibitors metabolized by CYP3A4, such as lovastatin and simvastatin, are also contraindicated with Itrazol® (Itrazol injection). Ergot alkaloids metabolized by CYP3A4 such as dihydroergotamine, ergometrine (ergonovine), ergotamine and methylergometrine (methylergonovine) are contraindicated with Itrazol®.
Itrazol® (Itrazol injection) is contraindicated for patients who have shown hypersensitivity to Itrazol or its excipients. There is no information regarding cross-hypersensitivity between Itrazol and other azole antifungal agents. Caution should be used when prescribing Itrazol® (Itrazol injection) to patients with hypersensitivity to other azoles.
Itrazol IV cannot be used when administration of Sodium Chloride Injection is contraindicated.
The excipient hydroxypropyl-β-cyclodextrin is eliminated through glomerular filtration. Therefore, Itrazol IV is contraindicated in patients with severe renal impairment (defined as creatinine clearance below 30 mL/min).
Active ingredient matches for Itrazol:
Itraconazole in Brazil, Greece, Oman, Russian Federation.
| Unit description / dosage (Manufacturer) | Price, USD |
| Capsule; Oral; Itraconazole 100 mg | |
List of Itrazol substitutes (brand and generic names): | |
| Itrazile (Georgia) | |
| Itrazol 100mg (Oman) | |
| Itrazole (Taiwan, Thailand) | |
| Itrazole 100 mg x 25 x 4's (Millimed) | |
| Itrazole 10 mg/1 mL x 150 mL (Millimed) | |
| Itrazole cap 100 mg 25 x 4's (Millimed) | |
| Itrazole 100mg Capsule (Millimed) | $ 0.14 |
| Itrazole 200mg Tablet (Millimed) | $ 0.29 |
| Itriben | |
| Itriben 100mg Tablet (Jenburkt Pharmaceuticals Ltd) | $ 0.13 |
| Itriben 200mg Capsule (Jenburkt Pharmaceuticals Ltd) | $ 0.24 |
| Itrizole (Japan) | |
| Itrizole 1% (Japan) | |
| Itrizole 50 (Japan) | |
| Itrocap | |
| Itrocap 100mg Capsule (Smart Laboratories Pvt Ltd) | $ 0.14 |
| Itrocap 200mg Capsule (Smart Laboratories Pvt Ltd) | $ 0.19 |
| Itrocol (India) | |
| Itrocol 100mg CAP / 4 (Olcare) | $ 1.69 |
| ITROCOL cap 100 mg x 4's (Olcare) | $ 1.69 |
| Itrokast (Poland) | |
| Itrol (Colombia, Dominican Republic) | |
| ITROLE (India) | |
| 100 mg x 4's (Chemo Biological) | $ 1.64 |
| Itrole 100 mg Capsule (Chemo Biological) | $ 0.41 |
| Itrole 10mg CAP / 4 (Chemo Biological) | $ 1.64 |
| ITROLE cap 100 mg x 4's (Chemo Biological) | $ 1.64 |
| Itrole 10mg CAP / 4 (Chemo Biological) | $ 1.64 |
| ITROMED | |
| ITROMED 100MG CAPSULE 1 strip / 4 capsules each (Leeford Healthcare Ltd) | $ 0.95 |
| ITROMED 200MG CAPSULE 1 strip / 4 capsules each (Leeford Healthcare Ltd) | $ 2.17 |
| Itromed 200mg Capsule (Leeford Healthcare Ltd) | $ 0.54 |
| Itrosac (India) | |
| Itrosac 100mg CAP / 10 (Sac Pharma) | $ 1.93 |
| ITROSAC cap 100 mg x 10's (Sac Pharma) | $ 1.93 |
| ITROSTRED | |
| ITROSTRED 100MG CAPSULE 1 strip / 4 capsules each (Leeford Healthcare Ltd) | $ 0.41 |
| ITROZ (India) | |
| ITROZ tab 100 mg x 4's (Dermis) | |
| ITUNGO (India) | |
| ITUNGO cap 100 mg x 4's (Orion) | |
| ITYZA | |
| ITYZA 200MG CAPSULE 1 strip / 7 capsules each (Abbott India Ltd) | $ 2.11 |
| ITYZA CAPSULE 1 strip / 7 capsules each (Abbott India Ltd) | $ 1.05 |
| Itzfor | |
| ITZHH | |
| ITZHH CAPSULE 100MG 1 strip / 4 capsules each (Hegde and Hegde Pharmaceutical LLP) | $ 1.63 |
| Itzhh 200mg Capsule (Hegde and Hegde Pharmaceutical LLP) | $ 0.48 |
| Itzol (Indonesia) | |
| Itzol 100 mg x 12's (Lapi) | $ 16.37 |
| ITZUCIA (India) | |
| 100 mg x 8's (United Biotech) | |
| Itzucia 100mg CAP / 8 (United Biotech) | |
| ITZUCIA cap 100 mg x 8's (United Biotech) | |
| Itzucia 100mg CAP / 8 (United Biotech) | |
| IYCOTIZOL | |
| IYCOTIZOL 100MG TABLET 1 strip / 4 tablets each (Rowan) | $ 1.65 |
See 813 substitutes for Itrazol | |
References
- DailyMed. "ITRACONAZOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "itraconazole". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "itraconazole". http://www.drugbank.ca/drugs/DB01167 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Itrazol are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Itrazol. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yet1 consumer reported price estimates
Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?The below mentioned numbers have been reported by ndrugs.com website users about whether the Itrazol drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
| Users | % | ||
|---|---|---|---|
| Not expensive | 1 | 100.0% | |
1 consumer reported time for results
To what extent do I have to use Itrazol before I begin to see changes in my health conditions?As part of the reports released by ndrugs.com website users, it takes 2 weeks and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Itrazol. To get the time effectiveness of using Itrazol drug by other patients, please click here.
| Users | % | ||
|---|---|---|---|
| 2 weeks | 1 | 100.0% | |
2 consumers reported age
| Users | % | ||
|---|---|---|---|
| > 60 | 1 | 50.0% | |
| 46-60 | 1 | 50.0% | |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
