What is Levodopa - Beida Pharm?
Levodopa - Beida Pharm (Levodopa - Beida Pharm) is an inhaled prescription medicine used to treat symptoms of Parkinson's disease that come back (OFF episodes) while you are taking another medicine called carbidopa and Levodopa - Beida Pharm.
Levodopa - Beida Pharm is not to be used in place of any medicine you take daily for Parkinson's disease.
It is not known if Levodopa - Beida Pharm is safe or effective in children.
Levodopa - Beida Pharm indications
Oral
Parkinsonism
Adult: Initially, 125 mg bid; increase gradually every 3-7 days according to response. Max dose: 8 g daily in divided doses.
Oral
Parkinsonism in conjunction with carbidopa
Adult: Patients not previously on Levodopa - Beida Pharm therapy: Initially, 25 mg carbidopa with 100 mg Levodopa - Beida Pharm tid; gradually increase in increments of 12.5 mg carbidopa with 50 mg Levodopa - Beida Pharm or 25 mg carbidopa with 100 mg Levodopa - Beida Pharm every day or on alternate days. Maintenance dose: 75-200 mg carbidopa with 750 mg to 2 g Levodopa - Beida Pharm daily in divided doses. Max carbidopa dose: 200 mg daily. Patients previously on Levodopa - Beida Pharm monotherapy: 20-25% of the dose previously taken 3 or 4 times daily. Patient previously on other Levodopa - Beida Pharm/dopa-decarboxylase combination therapy: Initial dose should provide the same daily Levodopa - Beida Pharm dose.
Oral
Parkinsonism in conjunction with benserazide
Adult: Patients not previously on Levodopa - Beida Pharm therapy: Initially, 50 mg 3 or 4 times daily; gradually increase in increments of 100 mg once or twice wkly. Increase initial dose to 100 mg tid for advanced disease stages. Maintenance dose: 400-800 mg daily in divided doses; most require <600 mg daily. Patients previously on Levodopa - Beida Pharm monotherapy: 10-15% of the usual dose previously taken. Patient previously on other Levodopa - Beida Pharm/dopa-decarboxylase combination therapy: Initially, 50 mg 3 or 4 times daily.
Elderly: Initially, 50 mg once or bid, then increase by 50 mg every 3rd or 4th day.
How should I use Levodopa - Beida Pharm?
Use Levodopa - Beida Pharm exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Levodopa - Beida Pharm is for use only in people who are currently taking carbidopa and Levodopa - Beida Pharm. Do not stop taking your daily Parkinson's medications or change your dosing schedule without your doctor's advice.
For best results, use Levodopa - Beida Pharm when an "off episode" begins (when your Parkinson's symptoms start to return). Do not use Levodopa - Beida Pharm more than 5 times per day.
Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.
Levodopa - Beida Pharm is a powder that comes with a special inhaler device and blister packs containing capsules of the medicine. You will load 2 capsules (one at a time) into the inhaler device each time you use the medicine. Pushing the handle of the device onto the mouthpiece will pierce the capsule and release the medicine into the inhaler.
Do not swallow a Levodopa - Beida Pharm capsule. It is for use only in the Levodopa - Beida Pharm inhaler device.
This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Levodopa - Beida Pharm.
Do not stop using Levodopa - Beida Pharm suddenly after long-term regular use, or you could have unpleasant withdrawal symptoms (fever, confusion, muscle stiffness, changes in breathing and heart rate). Ask your doctor how to safely stop using this medicine.
Store at room temperature away from moisture and heat. Keep each capsule in the blister pack until you ready to load the inhaler device. Do not store capsules inside the device.
Throw away the device when your capsules run out. Always use the inhaler device that comes with each new prescription.
Uses of Levodopa - Beida Pharm in details
Levodopa - Beida Pharm is used to treat symptoms such as stiffness, tremors, spasms, and poor muscle control associated with Parkinson disease and parkinsonism-like symptoms caused by taking certain other drugs such as chlorpromazine, fluphenazine, perphenazine.
Levodopa - Beida Pharm description
The naturally occurring form of dihydroxyphenylalanine and the immediate precursor of dopamine. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to dopamine. It is used for the treatment of parkinsonian disorders and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system. [PubChem]
Levodopa - Beida Pharm dosage
Levodopa - Beida Pharm Dosage
Generic name: Levodopa - Beida Pharm 42mg
Dosage form: capsule
Medically reviewed on January 3, 2019.
Levodopa - Beida Pharm capsules are for oral inhalation only and should be used only with the Levodopa - Beida Pharm inhaler.
Important Administration Instructions
Levodopa - Beida Pharm capsules are for oral inhalation only and should be used only with the Levodopa - Beida Pharm inhaler. Levodopa - Beida Pharm capsules must not be swallowed as the intended effect will not be obtained. Levodopa - Beida Pharm capsules should be stored in their blister package and only removed immediately before use.
Recommended Dosage
Levodopa - Beida Pharm should be taken when symptoms of an OFF period start to return.
The recommended dosage of Levodopa - Beida Pharm is oral inhalation of the contents of two 42 mg capsules (84 mg) as needed, up to 5 times a day. The maximum dose per OFF period is 84 mg, and the maximum daily dosage is 420 mg. Levodopa - Beida Pharm has been shown to be effective only in combination with carbidopa/Levodopa - Beida Pharm.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical Disclaimer
More about Levodopa - Beida Pharm (Levodopa - Beida Pharm)
- Levodopa - Beida Pharm Side Effects
- During Pregnancy or Breastfeeding
- Drug Interactions
- Drug class: dopaminergic antiparkinsonism agents
Professional resources
- Levodopa - Beida Pharm (FDA)
Related treatment guides
- Parkinson's Disease
Levodopa - Beida Pharm interactions
See also:
What other drugs will affect Levodopa - Beida Pharm?
Increased postural hypotension and possible reduced absorption with TCAs. Reduced effects with phenothiazines, butyrophenones, thioxanthenes and other antipsychotic agents; reserpine, papaverine, phenytoin, isoniazid. Reversal of effects of Levodopa - Beida Pharm monotherapy with pyridoxine. Exacerbation of abnormal involuntary movements and possibly delayed absorption with anticholinergics. Additive hypotensive effects with antihypertensive agents. Increased CNS toxicity with methyldopa. Exacerbation of parkinsonian symptoms with metoclopramide.
Potentially Fatal: Increased risk of hypertensive crises with nonselective MAOIs. Increased risk of cardiac arrhythmias with cyclopropane or halogenated anaesthetics.
Levodopa - Beida Pharm side effects
See also:
What are the possible side effects of Levodopa - Beida Pharm?
The following serious adverse reactions are discussed below and elsewhere in the labeling:
- Falling Asleep During Activities of Daily Living and Somnolence
- Withdrawal-Emergent Hyperpyrexia and Confusion
- Hallucinations/Psychosis
- Impulse Control/Compulsive Behaviors
- Dyskinesia
- Bronchospasm in Patients with Lung Disease
- Glaucoma
Clinical Trials Experience
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.
Adverse Reactions in Study 1
Table 1 lists the adverse reactions that occurred in at least 2% of patients with Parkinson's disease who were treated with Levodopa - Beida Pharm 84 mg and higher than placebo for OFF periods in Study 1. Study 1 was a double-blind, placebo-controlled study, in which 114 patients received Levodopa - Beida Pharm 84 mg (two 42 mg capsules) for an average of 2 doses per day, to a maximum of 5 times a day, and 112 patients received placebo. Levodopa - Beida Pharm-treated patients were 45-82 years of age (mean 63.5 years of age) and were predominantly male (72%) and white (94%). All patients were also treated with oral carbidopa/Levodopa - Beida Pharm. The most common adverse reactions (≥ 5% and higher than placebo) in Study 1 were cough, nausea, upper respiratory tract infection, and sputum discolored.
| Adverse Reactions | Levodopa - Beida Pharm 84 mg N=114 % | Placebo N=112 % |
|---|---|---|
| Respiratory, thoracic and mediastinal disorders | ||
| Cough | 15 | 2 |
| Sputum discolored | 5 | 0 |
| Nasal discharge discoloration | 2 | 0 |
| Oropharyngeal pain | 2 | 0 |
| Gastrointestinal disorders | ||
| Nausea | 5 | 3 |
| Vomiting | 3 | 0 |
| Infections and infestations | ||
| Upper respiratory tract infection | 6 | 3 |
| Nasopharyngitis | 3 | 2 |
| Bronchitis/pneumonia | 2 | 0 |
| Nervous system disorders | ||
| Dyskinesia | 4 | 1 |
| Headache | 2 | 0 |
| Injury, poisoning and procedural complications | ||
| Fall | 3 | 2 |
| Laceration | 2 | 0 |
| Skin abrasion | 2 | 0 |
| General disorders and administration site conditions | ||
| Chest discomfort | 2 | 0 |
| Investigations | ||
| Blood bilirubin increased | 2 | 0 |
| Red blood cell count decreased | 2 | 0 |
| Musculoskeletal and connective tissue disorders | ||
| Pain in extremity | 2 | 1 |
| Psychiatric disorders | ||
| Insomnia | 2 | 1 |
| Vascular disorders | ||
| Orthostatic hypotension/blood pressure decreased | 2 | 0 |
Adverse Reactions Leading to Discontinuation in Study 1
In Study 1, 6 of 114 patients (5%) in the Levodopa - Beida Pharm 84 mg group and 3 of 112 patients (3%) in the placebo group discontinued because of adverse reactions. The most common of these adverse reactions was cough, which lead to discontinuation in 2% of patients in the Levodopa - Beida Pharm 84 mg group and none in the placebo group.
Levodopa - Beida Pharm contraindications
See also:
What is the most important information I should know about Levodopa - Beida Pharm?
Monoamine oxidase (MAO) inhibitors and Levodopa - Beida Pharm should not be given concomitantly and these inhibitors must be discontinued 2 weeks prior to initiating therapy with Levodopa - Beida Pharm. Levodopa - Beida Pharm is contraindicated in patients with known hypersensitivity to the drug and in narrow angle glaucoma.
Because Levodopa - Beida Pharm may activate a malignant melanoma, it should not be used in patients with suspicious, undiagnosed skin lesions or a history of melanoma.
Active ingredient matches for Levodopa - Beida Pharm:
Levodopa in China.
List of Levodopa - Beida Pharm substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Eldopal (Netherlands) | |
| Eldopar | |
| Eldopatec | |
| Eurodopa | |
| Helfo-Dopa | |
| Inbrija | |
| Insulamina | |
| Laradopa | |
| Larodopa | |
| Capsule; Oral; Levodopa 100 mg (Cambridge) | |
| Capsule; Oral; Levodopa 250 mg (Cambridge) | |
| Capsule; Oral; Levodopa 500 mg (Cambridge) | |
| Tablet; Oral; Levodopa 100 mg (Cambridge) | |
| Tablet; Oral; Levodopa 250 mg (Cambridge) | |
| Tablet; Oral; Levodopa 500 mg (Cambridge) | |
| Ledopa | |
| Levedopa | |
| Levocarbin (Peru) | |
| Levodopa (Albania, Argentina, Aruba, Australia, Austria, Azerbaijan, Belarus, Bolivia, Bosnia & Herzegowina, Bulgaria, Cambodia, China, Croatia (Hrvatska), Cuba, Czech Republic, Denmark, Estonia, Ethiopia, Finland, Georgia, Germany, Greece, Hong Kong, Hungary, Iceland, Indonesia, Ireland, Italy, Jamaica, Japan, Kazakhstan, Laos, Lithuania, Luxembourg, Malta, Mexico, Moldova, Netherlands, New Zealand, Norway, Oman, Paraguay, Peru, Philippines, Poland, Portugal, Romania, Russian Federation, Serbia, Slovakia, Slovenia, South Africa, South Korea, Spain, Switzerland, Taiwan, Thailand, Trinidad & Tobago, Turkey, Turkmenistan, United Kingdom, Uzbekistan, Venezuela) | |
| L-dopa powder | $ 15.19 |
| Levodopa powder | $ 7.31 |
| Levodopa 250 mg | |
| Lévodopa | |
| L-dopa powder | $ 15.19 |
| Levodopa powder | $ 7.31 |
| Levodopa 250 mg | |
| L-dopa powder | $ 15.19 |
| Levodopa powder | $ 7.31 |
| Levodopa 250 mg | |
| Levodopa Fu Seng (Taiwan) | |
| Levodopa-c | |
| Madopar-F (India) | |
| Madopar-F Levodopa 200mg, Benserazide50mg TAB / 10 (NPIL (Cognex)) | $ 1.11 |
| 10's (NPIL (Cognex)) | $ 1.27 |
| MADOPAR-F tab 10's (NPIL (Cognex)) | $ 1.11 |
| Maipedopa | |
| Majormet (Taiwan) | |
| Majormet 1000's | |
| Parda | |
| Rigakin (Netherlands) | |
| Sobiodopa | |
| Symblyopia (China) | |
| Syndpa Plus | |
| Syndpa Plus Carbidopa 25mg, Levodopa 100mg TAB / 10 | $ 0.26 |
| Syndpa Plus Carbidopa 25mg, Levodopa 100mg TAB / 10 | $ 0.26 |
| Veldopa (United Kingdom) | |
| Weldopa | |
See 82 substitutes for Levodopa - Beida Pharm | |
References
- DailyMed. "CARBIDOPA; ENTACAPONE; LEVODOPA: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "levodopa". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "levodopa". http://www.drugbank.ca/drugs/DB01235 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Levodopa - Beida Pharm are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Levodopa - Beida Pharm. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
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Information checked by Dr. Sachin Kumar, MD Pharmacology
