Macphenicol indications
Infection caused by gm+ve & gm-ve microorganisms, GUT & GIT infection, typhoid & paratyphoid fever, resp tract infection & other infection caused by microorganisms sensitive to Macphenicol.
Macphenicol dosage
Oral
Sexually transmitted diseases; Susceptible infections
Adult: 1.5 g daily in divided doses, up to 3 g/day initially for severe infections.
Child: 30-100 mg/kg/day.
Renal impairment:
| CrCl (ml/min) | Dosage Recommendation |
| 30-60 | 500mg bid. |
| 10-30 | 500mg once daily. |
Oral
Gonorrhoea
Adult: 2.5 g/day for 1-2 days. Alternatively, 2.5 g on the 1st day followed by 2 g/day on each of 4 subsequent days.
Renal impairment:
| CrCl (ml/min) | Dosage Recommendation |
| 30-60 | 500mg bid |
| 10-30 | 500mg once daily. |
Macphenicol interactions
There are many other medicines that can interact with steroids. Below is only a partial list of these medicines:
aspirin (taken on a daily basis or at high doses);
a diuretic (water pill);
a blood thinner such as warfarin (Coumadin);
cyclosporine (Gengraf, Neoral, Sandimmune);
insulin or diabetes medications you take by mouth;
ketoconazole (Nizoral):
rifampin (Rifadin, Rifater, Rifamate, Rimactane); or
seizure medications such as phenytoin (Dilantin) or phenobarbital (Luminal, Solfoton).
Macphenicol side effects
The most common side effects following nasal inhalation of triamcinolone acetonide are nasal irritation and itching, increased cough, nausea or vomiting, sore throat, nasal congestion, sneezing, nasal burning, bloody nasal discharge, and nasal dryness. Other adverse effects reported with intranasal triamcinolone acetonide include headache, dizziness, and watery eyes. All of these are either mild or uncommon.problems with your vision;
swelling, rapid weight gain, feeling short of breath;
severe depression, unusual thoughts or behavior, seizure (convulsions);
bloody or tarry stools, coughing up blood;
pancreatitis (severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate);
low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling); or
dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).
Less serious side effects may include:
sleep problems (insomnia), mood changes;
acne, dry skin, thinning skin, bruising or discoloration;
slow wound healing;
increased sweating;
headache, dizziness, spinning sensation;
nausea, stomach pain, bloating;
muscle weakness;
changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist)
Macphenicol contraindications
Hypersensitivity to Macphenicol, anuria, severe renal disease, severe liver dysfunction. Not for prophylaxis or treatment of influenza, cough, throat infections.
Active ingredient matches for Macphenicol:
List of Macphenicol substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Lanacol (Indonesia) | |
| Lanacol 500 mg x 10 x 10's (Landson) | $ 14.88 |
| Masatirin | |
| Mycochlorin-T (Thailand) | |
| Mycochlorin-T 250 mg x 100's (S M Pharmaceutical) | |
| Mycochlorin-T cap 250 mg 100's (S M Pharmaceutical) | |
| Négérol (France) | |
| Neomyson | |
| Nikolam (Indonesia) | |
| Nilacol (Indonesia) | |
| Nilacol 500 mg x 100's (Nicholas) | $ 12.77 |
| Nufathiam (Indonesia) | |
| Nufathiam 500 mg x 5 x 10's (Nufarindo) | $ 19.03 |
| Nufathiam 125 mg/5 mL x 60 mL (Nufarindo) | |
| Opiphen (Indonesia) | |
| Opiphen 500 mg x 10 x 10's (Otto) | $ 32.24 |
| Opiphen 125 mg/5 mL x 60 mL x 1's (Otto) | $ 1.92 |
| Phenobiotic (Indonesia) | |
| Pushijie (China) | |
| Racephenicol (Taiwan) | |
| Racephenicol 250 mg | |
| Renamoca (Indonesia) | |
| Rincrol | |
| Rindofen (Indonesia) | |
| Rindofen 250 mg x 10 x 10's (Yarindo Farmatama) | |
| Rindofen 500 mg x 10 x 10's (Yarindo Farmatama) | $ 21.08 |
| Sendicol (Indonesia) | |
| Sendicol 250 mg x 10 x 10's (Coronet) | $ 12.45 |
| Sendicol 500 mg x 10 x 10's (Coronet) | $ 32.37 |
| Sendicol 125 mg/5 mL x 60 mL x 1's (Coronet) | $ 2.00 |
| Sendicol Forte 250 mg/5 mL x 60 mL x 1's (Coronet) | $ 3.47 |
| Sendicol Forte (Indonesia) | |
| Sendicol/Sendicol Forte (Indonesia) | |
| Solathim (Indonesia) | |
| Solathim 500 mg x 10 x 10's (Solas) | $ 27.38 |
| Solathim 125 mg/5 mL x 60 mL x 1's (Solas) | $ 1.40 |
| Taf (Israel) | |
| TAF 1% POWDER 1 box / 100 GM powder each (Helios Pharmaceuticals) | $ 0.80 |
| Taf 1% w/w Powder (Helios Pharmaceuticals) | $ 0.80 |
| TAF 25% (Italy) | |
| TAF 28.5 mg/g (Netherlands) | |
| TAF 28.5 mg/g für Pferde, Rinder, Ziegen, Schafe, Schweine, Nerze und Kaninchen For horses, cattle, goats, pigs, minks and rabbits (Austria) | |
| Thiam-P (Thailand) | |
| Thiam-P 250 mg x 1's | |
| Thiam-P 500 mg x 1's | |
| Thiambiotic (Indonesia) | |
| Thiamcin (Thailand) | |
| Thiamcin 250 mg x 1, 000's (General Drugs House) | |
| Thiamcin cap 250 mg 1000's (General Drugs House) | |
| Thiamcol (Taiwan) | |
| Thiamcol / Sinton 250 mg | |
| Thiamcol / Union 250 mg x 100's | |
| Thiamcol / Union 250 mg x 1000's | |
| Thiamet (Indonesia) | |
| Thiamet 500 mg x 100's (Ethica) | $ 37.20 |
| Thiamet 1 g x 50's (Ethica) | $ 29.14 |
See 178 substitutes for Macphenicol | |
References
- PubChem. "thiamphenicol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "thiamphenicol". http://www.drugbank.ca/drugs/DB08621 (accessed September 17, 2018).
- DTP/NCI. "thiamphenicol: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Macphenicol are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Macphenicol. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
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Information checked by Dr. Sachin Kumar, MD Pharmacology
