Mebread Uses

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Mebread indications

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Oral

Oedema

Adult: 25-50 mg daily, increase if necessary to 75-100 mg. For long-term therapy: 25-50 mg every 2nd or 3rd day.

Oral

Hypertension

Adult: 25-50 mg daily alone or in combination with other antihypertensives, alternate-day maintenance dosage may be used.

Mebread dosage

Oral

Oedema

Adult: 25-50 mg daily, increase if necessary to 75-100 mg. For long-term therapy: 25-50 mg every 2nd or 3rd day.

Oral

Hypertension

Adult: 25-50 mg daily alone or in combination with other antihypertensives, alternate-day maintenance dosage may be used.

Mebread interactions

Increased toxicity of digitalis glycosides, allopurinol, tetracyclines. Increased risk of arrhythmia with drugs that prolong the QT interval. Hypotension with other antihypertensives, alcohol, barbiturates, opioids. Increased effects of neuromuscular blockers. Diuretic effects may be antagonised by NSAIDs, corticosteroids, carbenoxolone.

Potentially Fatal: Increased lithium toxicity.

Mebread side effects

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Electrolyte imbalance; hyperglycaemia; gout; dry mouth; thirst; weakness; muscle pain and cramp; seizures; hypotension; GI disturbances; anorexia; sialadenitis; headache; impotence; yellow vision; hypersensitivity reactions; cholestatic jaundice; pancreatitis; blood dyscrasias; dizziness; photosensitivity reactions, postural hypotension, paraesthesia.

Mebread contraindications

Severe hepatic or renal impairment; anuria; Addison's disease; hypercalcaemia.

Active ingredient matches for Mebread:

Mefruside in Japan.


List of Mebread substitutes (brand and generic names)

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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