What is Mechotane?
Mechotane is taken to treat certain disorders of the urinary tract or bladder. It helps to cause urination and emptying of the bladder. Mechotane may also be used for other conditions as determined by your doctor.
Mechotane is available only with your doctor's prescription.
Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, Mechotane is used in certain patients with the following medical conditions:
- Certain stomach problems
- Gastroesophageal reflux (caused by acid in the stomach washing back up into the esophagus)
- Megacolon (an abnormally large or dilated colon)
Mechotane indications
Mechotane Chloride Tablets USP are indicated for the treatment of acute postoperative and postpartum nonobstructive (functional) urinary retention and for neurogenic atony of the urinary bladder with retention.
How should I use Mechotane?
Use Mechotane as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Mechotane on an empty stomach, either 1 hour before or 2 hours after a meal. If taken soon after eating, nausea and vomiting may occur.
- If you miss a dose of Mechotane, take it as soon as possible. If it is more than 2 hours since your dose was to be taken, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Mechotane.
Uses of Mechotane in details
Mechotane is used to treat acute urirary retention after surgrey, childbirth and due to various diseases of the urinary bladder. Mechotane may also be used for treating a disease called congenital megacolon (abnormal dilatation of large intestine which is present from birth) and gastro-esophageal reflux and reflux esophagitis (inflammation of the esophagus due to regurgitation).
Mechotane description
Mechotane is a synthetic ester structurally and pharmacologically related to acetylcholine. A slowly hydrolyzed muscarinic agonist with no nicotinic effects, Mechotane is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, cardiac rate changes, and bronchial spasms. [PubChem]
Mechotane dosage
Mechotane Dosage
Generic name: Mechotane CHLORIDE 5mg
Dosage form: tablet
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Dosage must be individualized, depending on the type and severity of the condition to be treated.
Preferably give the drug when the stomach is empty. If taken soon after eating, nausea and vomiting may occur.
The usual adult oral dose ranges from 10 to 50 mg three or four times a day. The minimum effective dose is determined by giving 5 to 10 mg initially and repeating the same amount at hourly intervals until satisfactory response occurs, or until a maximum of 50 mg has been given. The effects of the drug sometimes appear within 30 minutes and are usually maximal within 60 to 90 minutes. The drug effects persist for about one hour.
If necessary, the effects of the drug can be abolished promptly by atropine (seeOVERDOSAGE).
More about Mechotane (Mechotane)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- En Espanol
- 1 Review - Add your own review/rating
Consumer resources
- Mechotane
- Mechotane (Advanced Reading)
- Other brands: Duvoid
Professional resources
- Mechotane (AHFS Monograph)
- Mechotane (FDA)
Related treatment guides
- GERD
- Abdominal Distension
- Urinary Retention
Mechotane interactions
See also:
What other drugs will affect Mechotane?
Acetylcholinesterase Inhibitors: May enhance the adverse/toxic effect of Cholinergic Agonists. Monitor therapy
Beta-Blockers: May enhance the adverse/toxic effect of Cholinergic Agonists. Of particular concern are the potential for cardiac conduction abnormalities and bronchoconstriction. Monitor therapy
Cimetropium: Cholinergic Agonists may diminish the anticholinergic effect of Cimetropium. Monitor therapy
Sincalide: Drugs that Affect Gallbladder Function may diminish the therapeutic effect of Sincalide. Management: Consider discontinuing drugs that may affect gallbladder motility prior to the use of sincalide to stimulate gallbladder contraction. Consider therapy modification
Mechotane side effects
See also:
What are the possible side effects of Mechotane?
Applies to Mechotane: elixir, solution, tablet
As well as its needed effects, Mechotane (the active ingredient contained in Mechotane) may cause unwanted side effects that require medical attention.
Severity: Moderate
If any of the following side effects occur while taking Mechotane, check with your doctor or nurse as soon as possible:
Rare - more common with the injection
- Shortness of breath, wheezing, or tightness in chest
Minor Side Effects
Some Mechotane side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:
Less common or rare: - more common with the injection
- Belching
- blurred vision or change in near or distance vision
- diarrhea
- dizziness or lightheadedness
- feeling faint
- frequent urge to urinate
- headache
- increased watering of mouth or sweating
- nausea or vomiting
- redness or flushing of skin or feeling of warmth
- seizures
- sleeplessness, nervousness, or jitters
- stomach discomfort or pain
Mechotane contraindications
See also:
What is the most important information I should know about Mechotane?
Hypersensitivity to Mechotane chloride tablets, hyperthyroidism, peptic ulcer, latent or active bronchial asthma, pronounced bradycardia or hypotension, vasomotor instability, coronary artery disease, epilepsy, and parkinsonism.
Mechotane chloride should not be employed when the strength or integrity of the gastrointestinal or bladder wall is in question, or in the presence of mechanical obstruction; when increased muscular activity of the gastrointestinal tract or urinary bladder might prove harmful, as following recent urinary bladder surgery, gastrointestinal resection and anastomosis, or when there is possible gastrointestinal obstruction; in bladder neck obstruction, spastic gastrointestinal disturbances, acute inflammatory lesions of the gastrointestinal tract, or peritonitis; or in marked vagotonia.
Active ingredient matches for Mechotane:
List of Mechotane substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Bethanechol | |
| Bethanechol / Johnson 25 mg x 1000's | |
| Duvoid (Canada, United States) | |
| Tablet; Oral; Bethanechol Chloride 10 mg (Roberts) | |
| Tablet; Oral; Bethanechol Chloride 25 mg (Roberts) | |
| Tablet; Oral; Bethanechol Chloride 50 mg (Roberts) | |
| Mechothane | |
| Mecothane | |
| Mictone | |
| Muscaran (Belgium) | |
| Myo Hermes (Spain) | |
| Myotonachol (United States, Canada) | |
| Tablet; Oral; Bethanechol Chloride 10 mg (Glenwood) | |
| Tablet; Oral; Bethanechol Chloride 25 mg (Glenwood) | |
| Tablet; Oral; Bethanechol Chloride 5 mg (Glenwood) | |
| Myotonine Chloride | |
| PHL-Bethanechol Chloride | |
| Tablet; Oral; Bethanechol Chloride 10 mg | |
| Tablet; Oral; Bethanechol Chloride 25 mg | |
| Tablet; Oral; Bethanechol Chloride 50 mg | |
| PHL-bethanechol Chloride tablet 10 mg (Pharmel Inc (Canada)) | |
| PHL-bethanechol Chloride tablet 25 mg (Pharmel Inc (Canada)) | |
| PHL-bethanechol Chloride tablet 50 mg (Pharmel Inc (Canada)) | |
| Uninechol (South Korea) | |
| Urabeth | |
| Urecholine | |
| Injectable; Injection; Bethanechol Chloride 5 mg / ml (Barr) | |
| Tablet; Oral; Bethanechol Chloride 10 mg (Barr) | |
| Tablet; Oral; Bethanechol Chloride 25 mg (Barr) | |
| Tablet; Oral; Bethanechol Chloride 5 mg (Barr) | |
| Tablet; Oral; Bethanechol Chloride 50 mg (Barr) | |
| 100 tablet in 1 bottle (Barr) | |
| Urecholine tablet 5 mg/1 (Barr) | |
| Urecholine tablet 10 mg/1 (Barr) | |
| Urecholine tablet 25 mg/1 (Barr) | |
| Urecholine tablet 50 mg/1 (Barr) | |
| Urecholine Chloride | |
| Uro-Carb | |
| Urotone | |
| UROTONE Capsule/ Tablet / 25mg / 5x10 units (Samarth Pharma Pvt. Ltd.) | $ 11.45 |
| Urotone 25mg TAB / 10 (Samarth Pharma Pvt. Ltd.) | $ 1.17 |
| 25 mg x 10's (Samarth Pharma Pvt. Ltd.) | $ 1.17 |
| Urotone 25 mg Tablet (Samarth Pharma Pvt. Ltd.) | $ 0.12 |
| UROTONE 25 MG TABLET 1 strip / 10 tablets each (Samarth Pharma Pvt. Ltd.) | $ 1.41 |
| UROTONE tab 25 mg x 10's (Samarth Pharma Pvt. Ltd.) | $ 1.17 |
| Urotone 25mg Tablet (Samarth Pharma Pvt. Ltd.) | $ 0.14 |
| Urotonine (India) | |
See 64 substitutes for Mechotane | |
References
- PubChem. "bethanechol". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "bethanechol". http://www.drugbank.ca/drugs/DB01019 (accessed September 17, 2018).
- MeSH. "Parasympathomimetics". https://www.ncbi.nlm.nih.gov/mesh/68... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Mechotane are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Mechotane. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
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Information checked by Dr. Sachin Kumar, MD Pharmacology
