Mefrin Side effects

• Side effects of Mefrin in details
• Mefrin contraindications
• Mefrin reviews

What are the possible side effects of Mefrin?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop taking Mefrin and seek medical attention or call your doctor at once if you have any of these serious side effects:

• chest pain, weakness, shortness of breath, slurred speech, problems with vision or balance;
• black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds;
• urinating less than usual or not at all;
• pain, burning, or bleeding when you urinate;
• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
• bruising, severe tingling, numbness, pain, muscle weakness.

Less serious side effects may include:

• upset stomach, mild heartburn or stomach pain, diarrhea, constipation; bloating, gas;
• dizziness, headache, nervousness;
• skin itching or rash;
• dry mouth;
• increased sweating, runny nose;
• blurred vision; or
• ringing in your ears.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Side effects of Mefrin in details

Applies to Mefrin: oral capsule

As well as its needed effects, Mefrin (the active ingredient contained in Mefrin) may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking Mefrin, check with your doctor immediately:

More common:

• Bloody urine
• bloody, black, or tarry stools
• decreased frequency or amount of urine
• heartburn
• increased bleeding time
• increased blood pressure
• increased thirst
• indigestion
• itching skin
• loss of appetite
• lower back or side pain
• nausea
• pale skin
• rashes
• severe abdominal pain, cramping, or burning
• stomach bloating
• swelling
• swelling of the face, fingers, feet, or lower legs
• trouble breathing with or without exertion
• unusual bleeding or bruising
• unusual tiredness or weakness
• vomiting
• vomiting of material that looks like coffee grounds, severe and continuing
• weight gain
• weight loss

Less common:

• Bleeding gums
• blood in vomit
• blurred vision
• burning feeling in the chest or stomach
• chest pain
• clay-colored stools
• cloudy urine
• confusion
• constipation
• cough or hoarseness
• dark urine
• difficult or labored breathing
• difficult, burning, or painful urination
• difficulty in swallowing
• dilated neck veins
• dizziness
• extreme fatigue
• fainting
• fast, pounding, or irregular heartbeat or pulse
• fever or chills
• frequent urge to urinate
• headache
• increased volume of pale, dilute urine
• irregular breathing
• irregular heartbeat
• large, flat, blue, or purplish patches in the skin
• light-colored stools
• lightheadedness
• nervousness
• noisy breathing
• pain or burning throat
• pinpoint red or purple spots on the skin
• pounding in the ears
• rapid, slow breathing
• redness, swelling, or soreness of tongue
• severe or continuing stomach pain
• shortness of breath
• slow heartbeat
• sore throat
• sores, ulcers, or white spots on the lips or tongue or inside the mouth
• stomach upset
• swelling or inflammation of the mouth
• swollen glands
• tenderness in the stomach area
• tightness in the chest
• tremors
• unpleasant breath odor
• upper right abdominal pain
• weight changes
• wheezing
• yellow eyes and skin

Rare

• Blistering, peeling, or loosening of the skin
• change in consciousness
• chest discomfort
• continuing vomiting
• cracks in the skin
• diarrhea
• dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
• drowsiness
• fever with or without chills
• flushed, dry skin
• fruit-like breath odor
• general body swelling
• general feeling of illness
• high fever
• hives
• increased hunger
• irregular, fast or slow, or shallow breathing
• joint or muscle pain
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• leg pain
• loss of consciousness
• loss of heat from the body
• no blood pressure
• no breathing
• no pulse
• nosebleeds
• painful glands
• pain or discomfort in the arms, jaw, back, or neck
• pains in the stomach, side, or abdomen, possibly radiating to the back
• pale or blue lips, fingernails, or skin
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• racing heartbeat or pulse
• red skin lesions, often with a purple center
• red, irritated eyes
• red, swollen skin
• redness or soreness of the skin
• scaly skin
• seeing, hearing, or feeling things that are not there
• seizures
• severe headache
• sneezing
• sores, welting, or blisters
• stiff neck and/or back
• sweating
• swollen, painful, or tender lymph glands in the neck, armpit, or groin
• unexplained weight loss

If any of the following symptoms of overdose occur while taking Mefrin, get emergency help immediately:

Symptoms of overdose:

• Unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

Minor Side Effects

Some Mefrin side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common:

• Acid or sour stomach
• belching
• continuing ringing or buzzing or other unexplained noise in the ears
• excess air or gas in the stomach or intestines
• full feeling
• hearing loss
• passing gas
• stomach discomfort

Less common:

• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• discouragement
• dry mouth
• fear
• feeling of constant movement of self or surroundings
• feeling sad or empty
• hair loss, thinning of the hair
• increased sensitivity of skin to sunlight
• irritability
• lack of appetite
• lack of interest or pleasure
• lack or loss of strength
• redness or other discoloration of the skin
• sensation of spinning
• severe sunburn
• sleepiness
• sleeplessness
• trouble concentrating
• trouble sleeping
• unable to sleep

Rare

• Appetite changes
• burning, dry, or itching eyes
• change in hearing
• discharge, excessive tearing
• redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid

What is the most important information I should know about Mefrin?

• Mefrin may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Mefrin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Serious stomach ulcers or bleeding can occur with the use of Mefrin. Taking it in high doses or for a long time, smoking, or drinking alcohol increases the risk of these side effects. Taking Mefrin with food will NOT reduce the risk of these effects. Contact your doctor or emergency room at once if you develop severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling.
• Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
• Mefrin is an NSAID. Before you start any new medicine, check the label to see if it has an NSAID (eg, ibuprofen) in it too. If it does or if you are not sure, check with your doctor or pharmacist.
• Do not take aspirin while you are using Mefrin unless your doctor tells you to.
• Mefrin may interfere with certain lab tests. Be sure your doctor and lab personnel know that you take Mefrin.
• Lab tests, including kidney function, complete blood cell counts, and blood pressure, may be performed while you use Mefrin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
• Use Mefrin with caution in the ELDERLY; they may be more sensitive to its effects, especially stomach bleeding and kidney problems.
• Mefrin should be used with extreme caution in CHILDREN younger than 14 years old; safety and effectiveness in these children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: Mefrin may cause harm to the fetus. Do not use it during the last 3 months of pregnancy. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Mefrin while you are pregnant. Mefrin is found in breast milk. Do not breast-feed while taking Mefrin.

Mefrin contraindications

Mefrin (Mefrin) is contraindicated in patients with known hypersensitivity to Mefrin.

Mefrin (Mefrin) should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. Severe, rarely fatal, anaphylactic-like reactions to NSAIDs have been reported in such patients.

Mefrin (Mefrin) is contraindicated for the treatment of peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery.

Mefrin (Mefrin) is contraindicated in patients with acute active ulceration or chronic inflammation of either the upper or lower gastrointestinal tract.

Mefrin (Mefrin) should not be used in patients with preexisting renal disease.

References

1. DailyMed. "MEFENAMIC ACID: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
2. DTP/NCI. "mefenamic acid: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).
3. European Chemicals Agency - ECHA. "Mefenamic acid: The information provided here is aggregated from the "Notified classification and labelling" from ECHA's C&L Inventory. ". https://echa.europa.eu/information-o... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Mefrin are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Mefrin. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

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Information checked by Dr. Sachin Kumar, MD Pharmacology