What is Metermine?
Metermine (Metermine) is a stimulant similar to an amphetamine. Metermine is an appetite suppressant that affects the central nervous system.
Metermine is used together with diet and exercise to treat obesity (overweight) in people with risk factors such as high blood pressure, high cholesterol, or diabetes.
Metermine may also be used for purposes not listed in this medication guide.
Metermine indications
Metermine™ tablets are indicated as a short-term (a few weeks) adjunct in a regimen of weight reduction based on exercise, behavioral modification and caloric restriction in the management of exogenous obesity in patients with an initial body mass index greater than or equal to 30 kg/m2, or greater than or equal to 27 kg/m2 in the presence of other risk factors (e.g., controlled hypertension, diabetes, hyperlipidemia).
Below is a chart of body mass index (BMI) based on various heights and weights.
BMI is calculated by taking the patient’s weight, in kilograms (kg), divided by the patient’s height, in meters (m), squared. Metric conversions are as follows: pounds ÷ 2.2 = kg; inches x 0.0254 = meters.
BODY MASS INDEX (BMI), kg/m2
The limited usefulness of agents of this class, including Metermine, should be measured against possible risk factors inherent in their use such as those described below.
How should I use Metermine?
Use Metermine orally disintegrating tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Metermine orally disintegrating tablets by mouth with or without food.
- Take Metermine orally disintegrating tablets in the morning unless your doctor directs you otherwise. Taking Metermine orally disintegrating tablets in the evening may cause trouble sleeping.
- Make sure that your hands are dry before removing Metermine orally disintegrating tablets from the bottle. Place the tablet on the top of your tongue where it will dissolve. The tablet dissolves quickly and can be swallowed with saliva. Metermine orally disintegrating tablets may be taken with or without water. Take the tablet immediately after removing it from the bottle. Do not store the removed tablet for future use.
- If you miss a dose of Metermine orally disintegrating tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Metermine orally disintegrating tablets.
Uses of Metermine in details
Metermine is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who are obese or have weight-related medical problems. Losing weight and keeping it off can lessen the many health risks that come with obesity, including heart disease, diabetes, high blood pressure, and a shorter life.
It is not known how this medication helps people to lose weight. It may work by decreasing your appetite, increasing the amount of energy used by your body, or by affecting certain parts of the brain. This medication is an appetite suppressant and belongs to a class of drugs called sympathomimetic amines.
How to use Metermine
Take this medication by mouth as directed by your doctor, usually once a day, 1 hour before breakfast or 1 to 2 hours after breakfast. If needed, your doctor may adjust your dose to take a small dose up to 3 times a day. Carefully follow your doctor's instructions. Taking this medication late in the day may cause trouble sleeping (insomnia).
If you are using sustained-release capsules, the dose is usually taken once a day before breakfast or at least 10 to 14 hours before bedtime. Swallow the medication whole. Do not crush or chew sustained-release capsules. Doing so can release all of the drug at once, increasing the risk of side effects.
If you are using the tablets made to dissolve in the mouth, the dose is usually taken once a day in the morning, with or without food. First, dry your hands before handling the tablet. Place your dose on top of the tongue until it dissolves, then swallow it with or without water.
The dosage is based on your medical condition and response to therapy. Your doctor will adjust the dose to find the best dose for you. Use this medication regularly and exactly as prescribed in order to get the most benefit from it. To help you remember, take it at the same time(s) each day.
This medication is usually taken for only a few weeks at a time. It should not be taken with other appetite suppressants. The possibility of serious side effects increases with longer use of this medication and use of this drug along with certain other diet drugs.
This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as depression, severe tiredness) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions right away.
Rarely, abnormal drug-seeking behavior (addiction) is possible with this medication. Do not increase your dose, take it more frequently, or use it for a longer time than prescribed. Properly stop the medication when so directed.
This medication may stop working well after you have been taking it for a few weeks. Talk with your doctor if this medication stops working well. Do not increase the dose unless directed by your doctor. Your doctor may direct you to stop taking this medication.
Metermine description
A central nervous system stimulant and sympathomimetic with actions and uses similar to those of dextroamphetamine. It has been used most frequently in the treatment of obesity. [PubChem]. Some common brand names for Metermine are Metermine® and Metermine™. Metermine is also available in combination medications such as Qsymia®.
Metermine dosage
Metermine Dosage
Generic name: Metermine HYDROCHLORIDE 37.5mg
Dosage form: tablet, orally disintegrating
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Exogenous Obesity
Dosage should be individualized to obtain an adequate response with the lowest effective dose.
The usual adult dose is one tablet as prescribed by the physician, administered in the morning, with or without food. Metermine is not recommended for use in pediatric patients less than or equal to 16 years of age.
Late evening medication should be avoided because of the possibility of resulting insomnia.
With dry hands, gently remove the Metermine (Metermine hydrochloride ODT) tablet from the bottle. Immediately place the Metermine tablet on top of the tongue where it will dissolve, then swallow with or without water.
More about Metermine (Metermine)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Espanol
- 1 Review - Add your own review/rating
Consumer resources
- Metermine orally disintegrating tablets
- Metermine
- Other brands: Metermine, Fastin, Ionamin, Metermine, More (7) »
Professional resources
- Metermine (FDA)
- Metermine Hydrochloride (AHFS Monograph)
Related treatment guides
- Obesity
- Weight Loss
Metermine interactions
See also:
What other drugs will affect Metermine?
Monoamine Oxidase Inhibitors
Use of Metermine is contraindicated during or within 14 days following the administration of monoamine oxidase inhibitors because of the risk of hypertensive crisis.
Alcohol
Concomitant use of alcohol with Metermine may result in an adverse drug reaction.
Insulin and
Oral Hypoglycemic Medications
Requirements may be altered.
Adrenergic Neuron Blocking Drugs
Metermine may decrease the hypotensive effect of adrenergic neuron blocking drugs.
Drug Abuse And Dependence
Controlled Substance
Metermine is a Schedule IV controlled substance.
Abuse
Metermine is related chemically and pharmacologically to the amphetamines. Amphetamines and other stimulant drugs have been extensively abused and the possibility of abuse of Metermine should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program.
Dependence
Abuse of amphetamines and related drugs may be associated with intense psychological dependence and severe social dysfunction. There are reports of patients who have increased the dosage of these drugs to many times that recommended. Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG. Manifestations of chronic intoxication with anorectic drugs include severe dermatoses, marked insomnia, irritability, hyperactivity and personality changes. A severe manifestation of chronic intoxication is psychosis, often clinically indistinguishable from schizophrenia.
Metermine side effects
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What are the possible side effects of Metermine?
Applies to Metermine: oral capsule, oral capsule extended release, oral tablet, oral tablet disintegrating
As well as its needed effects, Metermine (the active ingredient contained in Metermine) may cause unwanted side effects that require medical attention.
Major Side Effects
If any of the following side effects occur while taking Metermine, check with your doctor immediately:
Rare
- Seeing, hearing, or feeling things that are not there
- severe mental changes
- Chest pain
- decreased ability to exercise
- dizziness
- fainting
- fast, irregular, pounding, or racing heartbeat or pulse
- headache
- numbness or tingling in the arms or legs
- swelling of the feet or lower legs
- trembling or shaking of the legs, arms, hands, or feet
- trouble breathing
- trouble with thinking, speaking, or walking
- weakness
Minor Side Effects
Some Metermine side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:
Incidence not known:
- Decreased interest in sexual intercourse
- difficulty having a bowel movement (stool)
- dry mouth
- false or unusual sense of well-being
- hives or welts
- inability to have or keep an erection
- increased in sexual ability, desire, drive, or performance
- increased interest in sexual intercourse
- itching
- loss in sexual ability, desire, drive, or performance
- redness of the skin
- skin rash
- unpleasant taste
Metermine contraindications
See also:
What is the most important information I should know about Metermine?
Weight loss during pregnancy can harm an unborn baby, even if you are overweight. Do not use Metermine if you are pregnant.
Do not use Metermine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.
Taking Metermine together with other diet medications such as fenfluramine (Phen-Fen) or dexfenfluramine (Redux) can cause a rare fatal lung disorder called pulmonary hypertension. Do not take Metermine with any other diet medications without your doctor's advice.
Metermine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Drinking alcohol can increase certain side effects of Metermine.
Metermine is only part of a complete program of treatment that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.
Metermine may be habit-forming and should be used only by the person it was prescribed for. Never share Metermine with another person, especially someone with a history of drug abuse or addiction. Keep track of the amount of medicine used from each new bottle. Metermine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Do not stop using Metermine suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using Metermine.
Active ingredient matches for Metermine:
Phentermine in Australia.
List of Metermine substitutes (brand and generic names) | Sort by popularity |
Unit description / dosage (Manufacturer) | Price, USD |
Lonamin | |
Minobese | |
Mirapront | |
Mirubal (Venezuela) | |
Normaform | |
Normephentermine | |
Obe-Nix | |
Obenix | |
Obephen | |
Obermine | |
Obestin | |
Capsule; Oral; Phentermine Hydrochloride 30 mg | |
Capsules; Oral; Phentermine Hydrochloride 30 mg | |
Obestin-30 | |
Oby-Cap | |
Oby-Trim | |
Capsule; Oral; Phentermine Hydrochloride 30 mg | |
Capsules; Oral; Phentermine Hydrochloride 30 mg | |
ObyCap | |
ObyTrim | |
Capsule; Oral; Phentermine Hydrochloride 30 mg | |
Capsules; Oral; Phentermine Hydrochloride 30 mg | |
Omnibex | |
Ona Mast | |
Ona-Mast | |
Capsule; Oral; Phentermine Hydrochloride 30 mg | |
Tablet; Oral; Phentermine Hydrochloride 8 mg | |
Capsules; Oral; Phentermine Hydrochloride 30 mg | |
Tablets; Oral; Phentermine Hydrochloride 8 mg | |
Panbesy (Hong Kong, Singapore, South Korea, Thailand) | |
Panbesy 15 mg x 200's (Eurodrug) | |
Panbesy 30 mg x 200's (Eurodrug) | |
Capsules; Oral; Phentermine Hydrochloride 15 mg (Eurodrug) | |
Capsules; Oral; Phentermine Hydrochloride 30 mg (Eurodrug) | |
Panbesy cap 15 mg 200's (Eurodrug) | |
Panbesy cap 30 mg 200's (Eurodrug) | |
Panbesy nyscap 15 mg 200's (Eurodrug) | |
Panbesy nyscap 30 mg 200's (Eurodrug) | |
Panshape M | |
Pender (South Korea) | |
Pentmin (South Korea) | |
Phenkini (South Korea) | |
Phenteral | |
Phentercot | |
Phentermin Kukje (South Korea) | |
Phentermine Hydrochloride Actavis (United States) | |
Phentermine Hydrochloride Barr (United States) | |
See 182 substitutes for Metermine |
References
- PubChem. "phentermine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "phentermine". http://www.drugbank.ca/drugs/DB00191 (accessed September 17, 2018).
- DTP/NCI. "phentermine: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Metermine are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Metermine. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yetConsumer reported age
No survey data has been collected yetConsumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology