Micronac indications
Articular syndrome (rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout), degenerative and chronic inflammatory diseases of musculoskeletal system (osteochondrosis, osteoarthritis, periartropatii), post-traumatic inflammation of soft tissue and musculoskeletal system (sprains, bruises). Pain in the spine, neuralgia, myalgia, arthralgia, pain and inflammation after surgery or injury, pain in gout, migraine, algomenorrhea, pain with Bursitis, proctitis, colic (biliary and renal), pain in infectious and inflammatory diseases of ENT organs.
For local use: the inhibition of miosis during surgery for cataract prevention of cystoid macular edema associated with removal and lens implantation, inflammatory eye non-infectious nature, post-traumatic inflammation in penetrating and nonpenetrating wound of the eyeball.
Uses of Micronac in details
It is used to relieve pain and swelling of joints (osteoarthritis), swelling of the small joints of hands and feet (rheumatoid arthritis), arthritis that mainly affect the spine (ankylosing spondylitis).
Micronac description
Micronac also contains the following excipients: Medium chain triglycerides, hard fat, gelatin, D-sorbitol, concentrated glycerin, titanium dioxide, yellow no. 5, red no. 40 and purified water.
Micronac dosage
FC tab: Usual Dose: 100 mg twice daily.
Renal Insufficiency: There is no evidence that the dosage of Micronac needs to be modified in patients with mild renal impairment, but as with other NSAIDs, caution should be exercised.
Hepatic Insufficiency: There is some evidence that the dose of Micronac should be reduced in patients with hepatic impairment and it is suggested that an initial dose of 100 mg be used.
SR tab: Adults: 1 tablet daily.
Children: There are no clinical data on the use of Micronac in children.
Gel: Adults: Gently rub 2-4 g (a circular shaped mass approximately 2-2.5 cm in diameter) 3-4 times daily. Maximum Daily Dose: 16 g. Maximum Weekly Dose: 112 g. A period of at least 4 hrs should be left between applications. The dose should not be applied >4 times in a 24-hr period. After application, the hands should be washed unless this is the treated site. Do not use for >14 days unless recommended by the physician.
Micronac interactions
Lithium: Micronac may increase plasma concentrations of lithium.
Cardiac Glycosides: NSAIDs may exacerbate cardiac failure and reduce the glomerular filtration rate in patients receiving glycosides due to increase plasma glycoside (including digoxin) levels.
Diuretics: Micronac, like other NSAIDs, may inhibit the activity of diuretics. Diuretics can increase the risk of nephrotoxicity of NSAIDs.
Anticoagulants: Like other NSAIDs, Micronac may enhance the activity of anticoagulants.
Methotrexate: Since NSAIDs may increase plasma levels, resulting in increased toxicity, caution should be exercised if NSAIDs and methotrexate are administered within 24 hrs of each other.
Mifepristone: NSAIDs should not be used for 8-12 days after mifepristone administration as NSAIDs can reduce the effect of mifepristone.
Other NSAIDs and Steroids: Concomitant therapy with aspirin, other NSAIDs and steroids may increase the frequency of adverse reactions, including the risk of gastrointestinal bleeding.
Cyclosporin: Cyclosporin nephrotoxicity may be increased by the effect of NSAIDs on renal prostaglandins.
Micronac side effects
The majority of adverse reactions reported have been reversible and of a minor nature. The most frequent are gastrointestinal disorders, in particular dyspepsia, abdominal pain, nausea and diarrhea, and occasional occurrence of dizziness. Dermatological complaints including pruritus and rash, and abnormal hepatic enzyme and serum creatinine levels have also been reported.
If serious adverse reactions occur, Micronac should be withdrawn.
Inform the physician or pharmacist in case of adverse effects related to Micronac used.
Micronac contraindications
Hypersensitivity to Micronac, acetylsalicylic acid or to any of the excipients of Micronac/Micronac SR.
FC tab/SR tab: Active or history of recurrent peptic ulcer/haemorrhage (≥2 distinct episodes of proven ulceration or bleeding); NSAIDs are contraindicated in patients who have previously shown hypersensitivity reactions (eg, asthma, rhinitis, angioedema or urticaria) in response to ibuprofen, aspirin or other NSAIDs; severe heart, hepatic and renal failure; history of gastrointestinal (GI) bleeding or perforation, related to previous NSAIDs therapy.
Gel: Patients with or without chronic asthma in whom attacks of asthma, urticaria or acute rhinitis are precipitated by aspirin or other NSAIDs; concomitant use of other products containing Micronac; concomitant use of oral NSAIDs.
Do not use in children and adolescents <14 years.
Use in pregnancy & lactation: FC tab/SR tab: NSAIDs should not be used during pregnancy or labour unless the potential benefit to the patient outweighs the potential risk to the fetus.
In limited studies available, NSAIDs can appear in the breast milk in very low concentrations. NSAIDs should, if possible, be avoided when breastfeeding.
Gel: Since no experience has been acquired with Micronac gel in pregnancy or lactation, it is not recommended for use in these circumstances.
Active ingredient matches for Micronac:
Aceclofenac in India.
| Unit description / dosage (Manufacturer) | Price, USD |
| 100 mg x 10's | $ 0.28 |
| Micronac 100mg TAB / 10 | $ 0.28 |
| MICRONAC EYE DROP 1 packet / 5 ML eye drop each (Micro Labs Ltd) | $ 1.54 |
| MICRONAC tab 100 mg x 10's (Micro HC) | $ 0.28 |
| Micronac 100mg TAB / 10 | $ 0.28 |
| Micronac 0.1% w/v Eye Drop (Micro Labs Ltd) | $ 1.69 |
List of Micronac substitutes (brand and generic names): | |
| Mervan (Bangladesh) | |
| MICRONAC GEL (India) | |
| 30g (Micro HC) | $ 0.66 |
| Micronac Gel Aceclofenac1.5%w/w, MethylSalicylate10%w/w, Menthol5%w/w, LinseedOil3%w/w, Capsicin0.01%w/w GEL / 30g (Micro HC) | $ 0.66 |
| Micronac Gel Aceclofenac 1.5%w/w, MethylSalicylate 10%w/w, Menthol 5%w/w, LinseedOil 3%w/w, Capsicin 0.01%w/w GEL / 30g (Micro HC) | $ 0.66 |
| MICRONAC GEL topical gel 30g (Micro HC) | $ 0.66 |
| Micronac Gel Aceclofenac 1.5%w/w, MethylSalicylate 10%w/w, Menthol 5%w/w, LinseedOil 3%w/w, Capsicin 0.01%w/w GEL / 30g (Micro HC) | $ 0.66 |
| MICRONAC-SR (India) | |
| 200 mg x 10's (Micro HC) | $ 0.42 |
| Micronac-SR 200mg TAB / 10 (Micro HC) | $ 0.42 |
| MICRONAC-SR tab 200 mg x 10's (Micro HC) | $ 0.42 |
| Micronac-SR 200mg TAB / 10 (Micro HC) | $ 0.42 |
| Mobenac (Georgia) | |
| Mobenac FC tab 100 mg 10's (Alkem Lab) | $ 4.40 |
| Mobenac FC tab 100 mg 50's (Alkem Lab) | |
| MOBIRIDE-SR (India) | |
| 200 mg x 10's (Merck) | $ 0.48 |
| MOBIRIDE-SR tab 200 mg x 10's (Merck) | $ 0.48 |
| MONCECLO TAB (India) | |
| MONCECLO TAB tab 100 mg x 10's (Acinom Healthcare) | $ 0.28 |
| MONCECLO-100 (India) | |
| 100 mg x 10's | $ 0.28 |
| MONCECLO-SR (India) | |
| 200 mg x 10's (Acinom Healthcare) | $ 0.39 |
| MONCECLO-SR modified-release tab 200 mg x 10's (Acinom Healthcare) | $ 0.39 |
| MOVACE (India) | |
| 100 mg x 10's (Alkem) | $ 0.14 |
| Movace 100mg FC-TAB / 10 (Alkem) | $ 0.14 |
| MOVACE SP TABLET 1 strip / 10 tablets each (Alkem) | $ 0.77 |
| MOVACE film-coated tab 100 mg x 10's (Alkem) | $ 0.24 |
| Movace 100mg FC-TAB / 10 (Alkem) | $ 0.14 |
| Movace SP Tablet (Alkem) | $ 0.08 |
| Movace-SR (India) | |
| Movace-SR 200mg TAB / 10 (Alkem) | $ 0.36 |
| 200 mg x 10's (Alkem) | $ 0.36 |
| MOVACE-SR tab 200 mg x 10's (Alkem) | $ 0.36 |
| MOVEL OD | |
| MOVEL OD 200 MG TABLET 1 strip / 10 tablets each (Emcee Pharmaceuticals Pvt Ltd) | $ 0.42 |
| Movel OD 200mg Tablet (Emcee Pharmaceuticals Pvt Ltd) | $ 0.04 |
| Movex (Bangladesh, Israel) | |
| Solution; Inhalation; Bromhexine Hydrochloride 2 mg / ml (Rayere) | |
| Tablet; Oral; Bromhexine Hydrochloride 8 mg (Rayere) | |
| MOVEX TABLET 1 strip / 10 tablets each (Rayere) | $ 0.21 |
| Movex Tablet (Rayere) | $ 0.02 |
| Movexx (India) | |
| Movexx 100mg FC-TAB / 10 (Cipla) | $ 0.24 |
| 100 mg x 10's (Cipla) | $ 0.24 |
| MOVEXX 100 MG TABLET 1 strip / 10 tablets each (Cipla) | $ 0.08 |
| MOVEXX film-coated tab 100 mg x 10's (Cipla) | $ 0.30 |
| MOVEXX film-coated tab 200 mg x 10's (Cipla) | $ 1.01 |
| Movexx 100mg Tablet (Cipla) | $ 0.01 |
| Movexx NA Gel (Cipla) | $ 0.32 |
| MOVIZ (India) | |
| MOVIZ Capsule/ Tablet / 100mg / 10 units (JB Chemicals (Unique)) | $ 0.28 |
| Moviz 100mg TAB / 10 (JB Chemicals (Unique)) | $ 0.28 |
See 2152 substitutes for Micronac | |
References
- DailyMed. "NEPAFENAC: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "Aceclofenac". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- PubChem. "Nepafenac". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Micronac are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Micronac. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
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Information checked by Dr. Sachin Kumar, MD Pharmacology
