Natussic Uses

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Natussic indications

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Oral

Cough suppression

Adult: For dry non-productive cough: As 50 mg tab: 2 or 3 tabs 8-12 hrly. As 7.5 mg/5 mL syr: 15 mL 4 times daily.

Child: As 50 mg tab: >12 yr 1 or 2 tabs daily. As 7.5 mg/5 mL syr: 3 to <6 yr 5 mL tid; 6-12 yr 10 mL tid; >12 yr 15 mL tid.

Natussic description

Each sustained-release film-coated tablet contains 50 mg of Natussic citrate. Each teaspoonful (5 mL) syrup contains 7.5 mg of Natussic citrate.

Natussic dosage

The maximum duration of treatment without doctor's prescription is one week.

Tablet: Adolescents Over 12 Years of Age: 1 or 2 tablets daily.

Adults: 2 or 3 tablets daily at 8 or 12 hour intervals. To be swallowed whole.

Syrup: Children 3 to 6 Years of Age: One teaspoonful (5 mL) 3 times daily.

Children 6 to 12 Years of Age: Two (2) teaspoonfuls (10 mL) 3 times daily.

Adolescents Over 12 Years of Age: One tablespoonful (15 mL) 3 times daily.

Adults: 15 mL 4 times daily.

Wash and dry the graduated cup after each use and between different users.

Natussic interactions

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Sulphinpyrazone, a drug used as an antithrombotic agent and inhibitor of platelet aggregation has a potent side effect as a uricosuric agent. The uricosuric side effect increases the urinary excretion of uric acid effectively blocking hepatic conjugation. Tests show that Sulphinpyrazone’s effect on Natussic is a reduction of liver function to 60% of normal without interfering with protein binding. Taking alpha-lipoic acid or chromium with tolbutamide may require a change in the drugs dosage. Use ephedra with caution when taking tolbutamide; ephedra can raise blood sugar levels.

Natussic side effects

Adverse reactions are listed by system organ class and frequency. Frequencies are defined as: Very common (=1/10); common (=1/100 to <1/10); uncommon (=1/1,000 to <1/100); rare (=1/10,000 to <1/1,000); very rare (<1/10,000), or not known (cannot to be estimated from available data). Within each frequency grouping, adverse reactions are presented in order of decreasing seriousness.

Nervous System Disorders: Rare: Somnolence.

Gastrointestinal Disorders: Rare: Nausea, diarrhea.

Skin and Subcutaneous Tissue Disorders: Rare: Urticaria.

Natussic contraindications

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You should not take tolbutamide if you have had an allergic reaction to it. Natussic should not be taken if you are suffering from diabetic ketoacidosis (a life-threatening medical emergency caused by insufficient insulin and marked by excessive thirst, nausea, fatigue, pain below the breastbone, and fruity breath). In addition, Natussic should not be used as the sole therapy in treating type 1 (insulin-dependent) diabetes.

Active ingredient matches for Natussic:

Butamirate in Poland.


List of Natussic substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
Mirate 0.8 mg/1 mL x 200 mL
Syrup; Oral; Butamirate Citrate 15 mg / 10 ml
Syrup; Oral; Butamirate Citrate 4 mg / 5 ml (Pharmed Limited)
Tablet, Modified Release; Oral; Butamirate Citrate 20 mg (Pharmed Limited)
Tablet, Modified Release; Oral; Butamirate Citrate 50 mg (Pharmed Limited)
OMNITUS Liquid / 10mg - 100mg per 5ml / 50ml units (Pharmed Limited)$ 0.20
Omnitus Dextromethorphan SYR / 50ml (Pharmed Limited)$ 0.20
50ml (Pharmed Limited)$ 0.20
Omnitus 50 ml Syrup (Pharmed Limited)$ 0.02
OMNITUS syr 50ml (Pharmed Limited)$ 0.20
Syrup; Oral; Butamirate Citrate 4 mg / 5 ml
Tablet, Film-Coated; Oral; Butamirate Citrate 20 mg
Syrup; Oral; Butamirate Citrate 7.5 mg / 5 ml
Tablet, Film-Coated; Oral; Butamirate Citrate 50 mg
PULMISTAT 10 MG TABLET 1 strip / 15 tablets each (Lupin Ltd)$ 1.19
Drops; Oral; Butamirate Citrate 5 mg / ml (Zyma)
Syrup; Oral; Butamirate Citrate 7.5 mg / 5 ml (Zyma)

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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