What is Nivate-NC?
Beclomethasone is a steroid. It prevents the release of substances in the body that cause inflammation.
Beclomethasone nasal is used to treat nasal symptoms such as congestion, sneezing, and runny nose caused by seasonal or year-round allergies. The Nivate-NC brand of this medication is also used to keep nasal polyps from coming back after surgery to remove them.
Beclomethasone may also be used for purposes not listed in this medication guide.
Nivate-NC indications
Beclomethasone dipropionate produces anti-inflammatory and vasoconstrictor effects. BECONE is indicated for the relief of the symptoms of seasonal or perennial allergic and nonallergic rhinitis. It is also indicated for the prevention of recurrence of nasal polyps following surgical removal.
Uses of Nivate-NC in details
Nivate-NC is used to treat runny nose, swelling and itching of the nose due to allergy (allergic rhinitis), hay fever and ulcerative colitis. Nivate-NC reduces inflammation, swelling and irritation in nose and helps to relieve itching, sneezing and blocked or runny nose. It is also used in asthma and ulcerative colitis.
Nivate-NC description
The dose which the patient gets through the mouthpiece of the device is 180 mcg.
Nivate-NC contains 200 doses of finely powdered beclomethasone dipropionate mixed in a small quantity of lactose. The amount of drug received by the patient (180 mcg/dose) corresponds to that from 2 puffs of the freon-based beclomethasone inhalation aerosol with a metered dose of 100 mcg/dose. The dose to be inhaled is released from the container by pressing the device between the thumb and the forefinger. This is followed by inhalation through the device. As a result, beclomethasone dipropionate particles are transferred to their target, the lungs. Use of the Nivate-NC does not require coordination of actuation of the dose and inhalation.
Nivate-NC dosage
Management of Chronic Asthma: Adults and Children >12 years: 100-400 mcg twice daily. Maximum: 1000 mcg twice daily.
Children (5-12 years): 100-200 mcg twice daily. Maximum: 200-400 mcg twice daily.
Prophylaxis of Asthma: Adults and Children >12 years: 50-200 mcg twice daily. Increase if necessary to maximum 400 mcg twice daily.
Children (5-12 years): The usual starting dose is 100 mcg twice daily. Depending on the severity of asthma, the daily dose may be increased up to 400 mcg administered in 2-4 divided doses.
When patient's symptoms remain under satisfactory control, the dose should be titrated to the lowest dose at which effective control of asthma is maintained.
Therapy in New Patients: Mild Asthma: 50-100 mcg twice daily.
Moderate Asthma: 100-200 mcg twice daily.
Severe Asthma: 200-400 mcg twice daily.
When switching a patient with well-controlled asthma from another corticosteroid inhaler, initially Nivate-NC 100 mcg puff should be prescribed for Nivate-NC (CFC) or budesonide 200-250 mcg; fluticasone propionate 100 mcg.
When switching a patient with poorly-controlled asthma from another corticosteroid inhaler, initially Nivate-NC 100 mcg puff should be prescribed for Nivate-NC (CFC) or budesonide or fluticasone propionate 100 mcg. The dose of Nivate-NC should be adjusted to response.
Use in the elderly or patients with hepatic or renal impairment: There are no special dosage recommendations for use in the elderly or in patients with hepatic or renal impairment.
Nivate-NC interactions
See also:
What other drugs will affect Nivate-NC?
No drug interactions have been described with inhaled beclomethasone.
Nivate-NC side effects
See also:
What are the possible side effects of Nivate-NC?
The most commonly noted side effects associated with inhaled beclomethasone are mild cough or wheezing due to chemical irritation; these effects may be minimized by using an inhaled bronchodilator (e.g., albuterol or Ventolin) prior to the beclomethasone.
Oral candidiasis or thrush, a fungal infection of the mouth and throat, can occur in between 1 in 20 and 1 in 8 persons who use beclomethasone. The risk of thrush is greater with higher doses, but the risk in children is lower than in adults. Hoarseness may occur in as few as 1 in 20 or as many as 1 in 2 persons and is due to chemical irritation. A spacer device that can be attached to the inhaler and washing out the mouth with water following each use of beclomethasone reduces the amount of beclomethasone in the mouth and throat and reduces the risk of thrush and hoarseness.
Higher doses of inhaled beclomethasone (more than 1000 mcg/day) may result in more absorption into the body. This may decrease bone formation and increase bone breakdown (resorption), resulting in weak bones and a risk of fractures. Even higher doses (more than 1500 mcg/day in adults and 400 mcg/day in children) may suppress the adrenal glands and impair their ability to make natural glucocorticoid. People with such suppression (which can be identified by testing) need increased amounts of glucocorticoid orally or by the intravenous route during periods of high physical stress since higher amounts of glucocorticoids are needed by the body to fight physical stress. Patients receiving beclomethasone may develop easy bruising if enough beclomethasone is absorbed into the body from the lungs.
Nivate-NC contraindications
Hypersensitivity to any of the ingredients of this preparation contraindicates its use. Status asthmaticus, acute episodes of asthma.
Active ingredient matches for Nivate-NC:
Beclometasone dipropionate in India.
Clotrimazole/neomycin sulphate in India.
| Unit description / dosage (Manufacturer) | Price, USD |
| 15g | |
| Nivate-NC Beclometasone dipropionate0.025 % w/w, Neomycin sulphate0.5 % w/w, Clotrimazole 0.1 %w/w. OINT / 15g | |
| NIVATE-NC oint 15g (Nitin) | |
| Nivate-NC Beclometasone dipropionate0.025 % w/w, Neomycin sulphate0.5 % w/w, Clotrimazole 0.1 %w/w. OINT / 15g | |
List of Nivate-NC substitutes (brand and generic names): | |
| Nistin C | |
| Nistin C Eye 3 gm Ointment (Jawa Pharmaceuticals (India) Pvt. Ltd.) | $ 0.42 |
| Nizoral Cool 2% (Vietnam) | |
| Noah Smearing Film (China) | |
| Normospor (South Africa) | |
| Nosecone (Taiwan) | |
| Nosecone 0.42 mg/1 g x 200 doses | |
| Notiderm NF (Peru) | |
| Novacetol (Chile) | |
| Tablet; Oral; Acetaminophen 250 mg; Aspirin 300 mg; Codeine Hydrochloride 10 mg (Prater) | |
| Cream; Topical; Clotrimazole 1% (Prater) | |
| Novadine VT | |
| Novadine VT Vaginal Pessary Pessary (Radico Remedies) | $ 0.15 |
| Nuforce CD | |
| Nuforce CD Vaginal 100+100 Capsule (Mankind Pharmaceuticals Pvt. Ltd.) | $ 0.08 |
| NUFORCE CD 100 MG/200 MG SUPPOSITORY 1 packet / 3 suppositorys each (Mankind Pharmaceuticals Pvt. Ltd.) | $ 0.87 |
| Nuforce CD3 | |
| Nuforce CD3 Vaginal 100+200 Suppository (Mankind Pharmaceuticals Pvt. Ltd.) | $ 0.20 |
| NUFORCE DUST POWD (India) | |
| 1 % w/w x 75g (Mankind (Discovery)) | $ 0.32 |
| Nuforce Dust Powd 1% w/w PWD / 75g (Mankind (Discovery)) | $ 0.32 |
| NUFORCE DUST POWD topical powd 1 % w/w x 75g (Mankind (Discovery)) | $ 0.32 |
| Nuforce Dust Powd 1% w/w PWD / 75g (Mankind (Discovery)) | $ 0.32 |
| Nuforce Mouth Paint (India) | |
| Nuforce Mouth Paint 1% w/v M-PAINT / 15ml (Mankind (Discovery)) | $ 0.31 |
| 1 % w/v x 15ml (Mankind (Discovery)) | $ 0.31 |
| NUFORCE MOUTH PAINT mouth paint 1 % w/v x 15ml (Mankind (Discovery)) | $ 0.31 |
| Nuforce V6 (India) | |
| Nuforce V6 100mg VAG-TAB / 6 (Mankind Pharmaceuticals Pvt. Ltd.) | $ 0.29 |
| 100 mg x 6's (Mankind Pharmaceuticals Pvt. Ltd.) | $ 0.29 |
| Nuforce V6 100 mg Tablet (Mankind Pharmaceuticals Pvt. Ltd.) | $ 0.05 |
| Nuforce-GM (India) | |
| Nuforce-GM Beclometasone dipropionate0.025 % w/w, Clotrimazole 1 %w/w, Gentamicin sulphate 0.1 %w/w. CRM / 15g (Mankind) | $ 0.20 |
| 15g (Mankind) | $ 0.20 |
| NUFORCE-GM cream 15g (Mankind) | $ 0.20 |
| NUFORCE-V6 (India) | |
| NUFORCE-V6 vag tab 100 mg x 6's (Mankind (Discovery)) | $ 0.29 |
| O Care | |
| O Care Ear 5 ml Drop (Divine Healthcare) | $ 0.37 |
| Obactin BCL | |
| Obactin BCL 10 ml Drop (Meridian Medicare Ltd.) | $ 0.05 |
| Odis | |
| Odis Mouth/Throat 15 ml Mouth Wash/Gargle (Odin Healthcare Pvt Ltd) | $ 0.46 |
| Oenss (Vietnam) | |
| Oenss 100 mg x 1 Blister x 10 Tablet | |
| Oenss 100 mg x 10 Blister x 10 Tablet | |
| Olclobee-GC (India) | |
| Olclobee-GC Beclometasone 0.025 % w/w, neomycin 0.5 % w/w, clotrimazole 1 % w/w. CRM / 15g (Olcare (Olski)) | $ 0.47 |
| OLCLOBEE-GC cream 15g (Olcare (Olski)) | $ 0.47 |
| Olotic (India) | |
| Olotic Chloramphenicol, Lignocaine, Clotrimazole, Beclomethasone. EAR-DPS / 5ml (Zytras) | $ 0.39 |
| Olotic Chloramphenicol , Lignocaine , Clotrimazole , Beclomethasone. EAR-DPS / 5ml (Zytras) | $ 0.39 |
| 5ml (Zytras) | $ 0.39 |
| Olotic Chloramphenicol, lignocaine, clotrimazole, beclomethasone. EAR DPS / 5ml (Zytras) | $ 0.39 |
| OLOTIC ear drops 5ml (Zytras) | $ 0.39 |
| Onderm (India) | |
| Onderm Neomycin sulphate 0.5 % w/w, Clotrimazole 1 % w/w, Beclomethasone dipropionate0.025 % w/w. CRM / 10g (Obsurge Biotech Limited) | $ 0.39 |
| 10g (Obsurge Biotech Limited) | $ 0.39 |
| Onderm Skin 10 gm Ointment (Obsurge Biotech Limited) | $ 0.39 |
| ONDERM 0.025%W/W/0.5%W/W/1%W/W OINTMENT 1 tube / 10 GM ointment each (Obsurge Biotech Limited) | $ 0.47 |
See 3893 substitutes for Nivate-NC | |
References
- DailyMed. "HYDROCORTISONE; NEOMYCIN SULFATE; POLYMYXIN B SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "BETAMETHASONE DIPROPIONATE; CLOTRIMAZOLE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "neomycin". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Nivate-NC are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Nivate-NC. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
