Ocu-Disal Uses

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What is Ocu-Disal?

Ocu-Disal is the chemical name for salt. Ocu-Disal can reduce some types of bacteria in certain body secretions, such as saliva.

Ocu-Disal inhalation is used to produce sputum (mucus, or phlegm) from the mouth to help improve lung function in people with cystic fibrosis, or to collect sputum for medical testing. This medication may also be used to dilute other medications inhaled through a nebulizer.

Ocu-Disal inhalation may also be used for other purposes not listed in this medication guide.

Ocu-Disal indications

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Airlife Modudose Ocu-Disal as isotonic solution: the dehydration of various origins. To maintain the volume of blood plasma during and after surgery. As a solvent for various drugs.

Hypertonic solution: violations of water-electrolyte metabolism: lack of sodium and chlorine ions; hypoosmotic dehydration of various origins (due to prolonged vomiting, diarrhea, burns with a gastric fistula, pulmonary hemorrhage, intestinal bleeding).

Eye drops and ointment: irritation of the cornea with inflammatory and allergic diseases (combined therapy).

How should I use Ocu-Disal?

Use Ocu-Disal nebulizer solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Ocu-Disal nebulizer solution.

Uses of Ocu-Disal in details

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This product is used to treat dryness inside the nose (nasal passages). It helps add moisture inside the nose to dissolve and soften thick or crusty mucus. In babies and young children with stuffy noses who cannot blow their noses, using this product helps to make the mucus easier to remove with a nasal bulb syringe. This helps relieve stuffiness and makes breathing easier.

This product contains a purified gentle salt solution (also called saline or Ocu-Disal solution). It does not contain any medication.

How to use Ocu-Disal nasal

Spray this product into each nostril as needed or as directed by your doctor. This product may also be given into the nose as drops or a stream. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

Try not to touch the container tip to the inside of your nose. If this happens, rinse the tip with hot water and dry with a clean tissue before recapping the container.

If your condition persists or worsens, or if you think you may have a serious medical problem, seek immediate medical attention.

Ocu-Disal description

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Ocu-Disal, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Ocu-Disal is the salt most responsible for the salinity of seawater and of the extracellular fluid of many multicellular organisms. It is listed on the World Health Organization Model List of Essential Medicines.

Ocu-Disal dosage

All injections in VIAFLEX plastic containers are intended for intravenous administration using sterile and nonpyrogenic equipment.

As directed by a physician. Dosage, rate, and duration of administration are to be individualized and depend upon the indication for use, the patient’s age, weight, clinical condition, concomitant treatment, and on the patient’s clinical and laboratory response to treatment.

When other electrolytes or medicines are added to this solution, the dosage and the infusion rate will also be dictated by the dose regimen of the additions.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit. Use of a final filter is recommended during administration of all parenteral solutions, where possible.

Do not administer unless the solution is clear and seal is intact.

Additives may be incompatible with Ocu-Disal Injection, USP. As with all parenteral solutions, compatibility of the additives with the solution must be assessed before addition. Before adding a substance or medication, verify that it is soluble and/or stable in water and that the pH range of Ocu-Disal Injection, USP is appropriate. After addition, check for unexpected color changes and/or the appearance of precipitates, insoluble complexes or crystals.

The instructions for use of the medication to be added and other relevant literature must be consulted. Additives known or determined to be incompatible must not be used. When introducing additives to Ocu-Disal Injection, USP, aseptic technique must be used. Mix the solution thoroughly when additives have been introduced. Do not store solutions containing additives.

After opening the container, the contents should be used immediately and should not be stored for a subsequent infusion. Do not reconnect any partially used containers. Discard any unused portion.

Ocu-Disal interactions

See also:
What other drugs will affect Ocu-Disal?

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Caution must be exercised in the administration of Ocu-Disal Injection, USP to patients receiving corticosteroids or corticotropin.

Studies have not been conducted to evaluate additional drug/drug or drug/food interactions with Ocu-Disal (Ocu-Disal (Ocu-Disal injection) injection) Injection, USP.

Ocu-Disal side effects

See also:
What are the possible side effects of Ocu-Disal?

Post-Marketing Adverse Reactions

The following adverse reactions have been identified during postapproval use of Ocu-Disal Injection, USP. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

The following adverse reactions have been reported in the post-marketing experience during use of 0.9% Ocu-Disal Injection, USP and include the following:

hypersensitivity/infusion reactions, including hypotension, pyrexia, tremor, chills, urticaria, rash, and pruritus.

Also reported are infusion site reactions, such as infusion site erythema, injection site streaking, burning sensation, and infusion site urticaria.

The following adverse reactions have not been reported with 0.9% Ocu-Disal Injection, USP but may occur: hypernatremia, hyperchloremic metabolic acidosis, and hyponatremia, which may be symptomatic.

Hyponatremia has been reported for 0.45% Ocu-Disal Injection, USP.

The following adverse reactions have not been reported with 0.45% Ocu-Disal Injection, USP but may occur: hyperchloremic metabolic acidosis, hypersensitivity/infusion reactions (including hypotension, pyrexia, tremor, chills, urticaria, rash, and pruritus), and infusion site reactions (such as infusion site erythema, injection site streaking, burning sensation, infusion site urticaria).

If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary.

Ocu-Disal contraindications

See also:
What is the most important information I should know about Ocu-Disal?

Due to potential toxicity of benzyl alcohol in newborns, Bacteriostatic Ocu-Disal Injection, USP, 0.9% containing benzyl alcohol must not be used in this patient population.

Bacteriostatic Ocu-Disal Injection, USP, 0.9% should not be used for fluid or Ocu-Disal replacement.

Active ingredient matches for Ocu-Disal:

Sodium chloride


List of Ocu-Disal substitutes (brand and generic names)

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Unit description / dosage (Manufacturer)Price, USD
5 % w/v x 10ml (Le Sante (Cadila Pharmaceuticals Ltd.))$ 0.23
Ocutone 5% w/v EYE-DPS / 10ml (Le Sante (Cadila Pharmaceuticals Ltd.))$ 0.23
Ocutone Eye 10 ml Drop (Le Sante (Cadila Pharmaceuticals Ltd.))$ 0.23
OCUTONE eye drops 5 % w/v x 10ml (Le Sante (Cadila Pharmaceuticals Ltd.))$ 0.23
Ocutone 5% w/v EYE-DPS / 10ml (Le Sante (Cadila Pharmaceuticals Ltd.))$ 0.23
Drops; Nasal; Sodium Chloride (Pfizer consumer)
Spray; Nasal; Sodium Chloride (Pfizer consumer)
Olyte-E sodium chloride 2.6 g, potassium chloride 1.5 g, Sodium citrate 2.9 g, anhydrous dextrose 13.5 g. POWD / 21.80 (Olcare)$ 0.20
Liquid; Ophthalmic; Sodium Chloride 0.44%
Opticlear solution/ drops .5 mg/mL (Major Pharmaceuticals (US))
Solution; Ophthalmic; Sodium Chloride 0.9%
ORS L 200 ml Solution (Juggat Pharma)$ 0.27
Ors-L Plus Sodium chloride 250 mg, potassium chloride 300 mg, sodium citrate 580 mg, dextrose 5.4 g, taurine 100mg, calcium lactate 80 mg, magnesium sulphate 100 mg, carbohydrates 24 g. O-LIQD / 200ml (J & J)$ 0.27
ORS-L PLUS oral liqd 200ml (J & J)$ 0.27
OSMOEYE eye oint 6 % w/w x 3g (Eyekare)$ 1.57
Osmoeye 5% w/v Eye Drop (Eyekare)$ 0.51
Osmoeye 6% w/v Eye Ointment (Eyekare)$ 1.57
Osmoeye 5% w/v Gel (Eyekare)$ 0.51
Osolin 0.65% w/v N-DPS / 15ml (Olcare (Fusion))$ 0.27
OSOLIN nasal drops 0.65 % w/v x 15ml (Olcare (Fusion))$ 0.27
Otricare-S 0.65% w/v N-DPS / 20ml (Biotabs)$ 0.34
OTRICARE-S nasal drops 0.65 % w/v x 20ml (Biotabs)$ 0.34
OTRINOZ -S 0.74% NASAL DROPS 1 packet / 10 ML nasal drops each (Novartis India Ltd)$ 0.43
Otrivin S Nasal 10 ml Drop (Novartis India Ltd)$ 0.33
Otrivin S 0.74% w/v Nasal Spray (Novartis India Ltd)$ 0.53
0.74 % w/v x 10ml (Novartis (OTC))$ 0.30
Otrivin-S 0.74% w/v N-DPS / 10ml (Novartis (OTC))$ 0.30
OTRIVIN-S nasal spray 0.74 % w/v x 10ml (Novartis (OTC))$ 0.45

References

  1. DailyMed. "AMINO ACIDS; CALCIUM ACETATE; GLYCERIN; MAGNESIUM ACETATE; PHOSPHORIC ACID; POTASSIUM CHLORIDE; SODIUM ACETATE; SODIUM CHLORIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "sodium chloride". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "Sodium Chloride". http://www.drugbank.ca/drugs/DB09153 (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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