What is Odipril H?
Odipril H is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.
Odipril H is also used to treat fluid retention (edema) that is caused by congestive heart failure, severe liver disease (cirrhosis), kidney disease, or treatment with a steroid or hormone medicine.
Odipril H is a thiazide diuretic (water pill). It is used to help reduce the amount of water in the body by increasing the flow of urine. It may also be used for other conditions as determined by your doctor.
Odipril H is available only with your doctor's prescription.
Odipril H indications
Odipril H Capsules are indicated in the management of hypertension either as the sole therapeutic agent, or in combination with other antihypertensives. Unlike potassium sparing combination diuretic products, Odipril H Capsules may be used in those patients in whom the development of hyperkalemia cannot be risked, including patients taking ACE inhibitors.
Usage in Pregnancy: The routine use of diuretics in an otherwise healthy woman is inappropriate and exposes mother and fetus to unnecessary hazard. Diuretics do not prevent development of toxemia of pregnancy, and there is no satisfactory evidence that they are useful in the treatment of developed toxemia.
Edema during pregnancy may arise from pathological causes or from the physiologic and mechanical consequences of pregnancy. Diuretics are indicated in pregnancy when edema is due to pathologic causes, just as they are in the absence of pregnancy. Dependent edema in pregnancy resulting from restriction of venous return by the expanded uterus is properly treated through elevation of the lower extremities and use of support hose; use of diuretics to lower intravascular volume in this case is illogical and unnecessary. There is hypervolemia during normal pregnancy which is harmful to neither the fetus nor the mother (in the absence of cardiovascular disease), but which is associated with edema, including generalized edema in the majority of pregnant women. If this edema produces discomfort, increased recumbency will often provide relief. In rare instances this edema may cause extreme discomfort which is not relieved by rest. In these cases a short course of diuretics may provide relief and may be appropriate.
How should I use Odipril H?
Use Odipril H capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Odipril H capsules by mouth with or without food.
- If you take colestipol or cholestyramine for high cholesterol, ask your doctor or pharmacist how to take it with Odipril H capsules.
- Odipril H capsules may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.
- If you miss a dose of Odipril H capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Odipril H capsules.
Uses of Odipril H in details
This medication is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Odipril H is a "water pill" (diuretic) that causes you to make more urine. This helps your body get rid of extra salt and water.
This medication also reduces extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, or kidney disease. This can lessen symptoms such as shortness of breath or swelling in your ankles or feet.
How to use Odipril H
Take this medication by mouth as directed by your doctor, usually once daily in the morning with or without food. It is best to avoid taking this medication within 4 hours of your bedtime to prevent having to get up to urinate.
The dosage is based on your medical condition and response to treatment.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick.
Cholestyramine and colestipol can decrease the absorption of Odipril H. If you are taking either of these drugs, take them at least 4 hours before or after taking Odipril H.
Tell your doctor if your condition does not improve or if it worsens (for example, your blood pressure readings increase).
Odipril H description
Each film-coated tablet contains losartan potassium 50 mg and Odipril H 12.5 mg.
Losartan potassium is 2-Butyl-4-chloro-1-[p-o-1H-tetrazol-5-yl-phenyl)benzyl]imidazole-5-methanol, potassium. Its empirical formula is C22H22ClKN6O and molecular weight is 461.
Odipril H is 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide. Its empirical formula is C7H8ClN3O4S2 and molecular weight is 297.7.
Odipril H dosage
Odipril H Dosage
Generic name: Odipril H 12.5mg
Dosage form: capsule, gelatin coated
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
For Control of Hypertension: The adult initial dose of Odipril H is one capsule given once daily whether given alone or in combination with other antihypertensives. Total daily doses greater than 50 mg are not recommended.
More about Odipril H (Odipril H)
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Consumer resources
- Odipril H
- Odipril H (Advanced Reading)
- Other brands: Aquazide H
Professional resources
- Odipril H (AHFS Monograph)
- Odipril H (FDA)
Related treatment guides
- Diabetes Insipidus
- Edema
- High Blood Pressure
- Nephrocalcinosis
- Osteoporosis
Odipril H interactions
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What other drugs will affect Odipril H?
DIAMOX®. modifies phenytoin metabolism with increased serum levels of phenytoin. This may increase or enhance the occurrence of osteomalacia in some patients receiving chronic phenytoin therapy. Caution is advised in patients receiving chronic concomitant therapy.
By decreasing the gastrointestinal absorption of primidone, DIAMOX may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. Caution is advised when beginning, discontinuing, or changing the dose of DIAMOX in patients receiving primidone.
Because of possible additive effects with other carbonic anhydrase inhibitors, concomitant use is not advisable.
Odipril H may increase the effects of other folic acid antagonists.
Odipril H may increase or decrease blood glucose levels. Consideration should be taken in patients being treated with antidiabetic agents.
Odipril H decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect.
Odipril H reduces urinary excretion of quinidine and may enhance its effect.
Odipril H may prevent the urinary antiseptic effect of methenamine.
Odipril H increases lithium excretion and the lithium may be decreased.
Odipril H and sodium bicarbonate used concurrently increases the risk of renal calculus formation.
Odipril H may elevate cyclosporine levels.
Odipril H side effects
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What are the possible side effects of Odipril H?
The adverse reactions associated with Odipril H have been shown to be dose related. In controlled clinical trials, the adverse events reported with doses of 12.5 mg Odipril H once daily were comparable to placebo. The following adverse reactions have been reported for doses of Odipril H 25 mg and greater and, within each category, are listed in the order of decreasing severity.
Body as a whole: Weakness.
Cardiovascular: Hypotension including orthostatic hypotension (may be aggravated by alcohol, barbiturates, narcotics or antihypertensive drugs).
Digestive: Pancreatitis, jaundice (intrahepatic cholestatic jaundice), diarrhea, vomiting, sialadenitis, cramping, constipation, gastric irritation, nausea, anorexia.
Hematologic: Aplastic anemia, agranulocytosis, leukopenia, hemolytic anemia, thrombocytopenia.
Hypersensitivity: Anaphylactic reactions, necrotizing angiitis (vasculitis and cutaneous vasculitis), respiratory distress including pneumonitis and pulmonary edema, photosensitivity, fever, urticaria, rash, purpura.
Metabolic: Electrolyte imbalance, hyperglycemia, glycosuria, hyperuricemia.
Musculoskeletal: Muscle Spasm.
Nervous System/Psychiatric: Vertigo, paresthesia, dizziness, headache, restlessness.
Renal: Renal failure, renal dysfunction, interstitial nephritis.
Skin: Erythema multiforme including Stevens-Johnson syndrome, exfoliative dermatitis including toxic epidermal necrolysis, alopecia.
Special Senses: Transient blurred vision, xanthopsia.
Urogenital: Impotence.
Whenever adverse reactions are moderate or severe, thiazide dosage should be reduced or therapy withdrawn.
Odipril H contraindications
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What is the most important information I should know about Odipril H?
You should not use this medication if you are allergic to Odipril H or if you are unable to urinate.
Before using this medication, tell your doctor if you have liver disease, kidney disease, glaucoma, asthma or allergies, gout, diabetes, or if you are allergic to sulfa drugs or penicillin.
Avoid drinking alcohol, which can increase some of the side effects of Odipril H.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.
There are many other drugs that can interact with Odipril H. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.
Active ingredient matches for Odipril H:
| Unit description / dosage (Manufacturer) | Price, USD |
| Odipril H 2.5+12.5 Capsule | $ 0.03 |
| ODIPRIL H 2.5 MG/12.5 MG CAPSULE 1 strip / 10 capsules each (Blue Cross Laboratories Ltd) | $ 0.36 |
| Odipril H 2.5 mg/12.5 mg Capsule (Blue Cross Laboratories Ltd) | $ 0.04 |
List of Odipril H substitutes (brand and generic names): | |
| Odipril HG | |
| Odipril HG 5 mg Capsule (Blue Cross Laboratories Ltd.) | $ 0.04 |
| Oditel H | |
| Oditel H 40+12.5 Tablet (Zinnia Life Sciences) | $ 0.06 |
| Olina (Dominican Republic) | |
| Olina 5 mg Anikem Labs Tablet (Anikem Laboratories) | $ 0.03 |
| Olina 10 mg Anikem Labs Tablet (Anikem Laboratories) | $ 0.06 |
| Olina 10 mg Tablet (Anikem Laboratories) | $ 0.06 |
| Olina 5 mg Tablet (Anikem Laboratories) | $ 0.03 |
| Olmat H | |
| Olmat H 40+12.5 Tablet (Carsyon (Micro Labs Ltd)) | $ 0.17 |
| Olmat H 20+12.5 Tablet (Carsyon (Micro Labs Ltd)) | $ 0.11 |
| Olmefast H | |
| Olmefast H 20+12.5 Tablet (Intra Labs India Pvt Ltd) | $ 0.10 |
| Olmesafe H | |
| Olmesafe H 40+12.5 Tablet (Otsira Genetica (Aristo Pharmaceuticals Pvt Ltd.)) | $ 0.13 |
| Olmesafe H 20+12.5 Tablet (Otsira Genetica (Aristo Pharmaceuticals Pvt Ltd.)) | $ 0.07 |
| OLMESAFE H 12.5MG/20MG TABLET 1 strip / 10 tablets each (Otsira Genetica (Aristo Pharmaceuticals Pvt Ltd.)) | $ 0.90 |
| OLMESAFE H 12.5MG/40MG TABLET 1 strip / 10 tablets each (Otsira Genetica (Aristo Pharmaceuticals Pvt Ltd.)) | $ 1.39 |
| Olmesafe H 12.5mg/20mg Tablet (Otsira Genetica (Aristo Pharmaceuticals Pvt Ltd.)) | $ 0.10 |
| Olmesafe H 12.5mg/40mg Tablet (Otsira Genetica (Aristo Pharmaceuticals Pvt Ltd.)) | $ 0.15 |
| Olmetor H | |
| Olmetor H 20+12.5 Tablet (Delta (Torrent Pharmaceuticals Ltd.)) | $ 0.09 |
| Olmetor H 40+12.5 Tablet (Delta (Torrent Pharmaceuticals Ltd.)) | $ 0.15 |
| OLMETOR H 12.5 MG/20 MG TABLET 1 strip / 10 tablets each (Delta (Torrent Pharmaceuticals Ltd.)) | $ 1.27 |
| OLMETOR H 12.5 MG/40 MG TABLET 1 strip / 10 tablets each (Delta (Torrent Pharmaceuticals Ltd.)) | $ 1.89 |
| Olmetrak H | |
| Olmetrak H 20+12.5 Tablet (USV Limited.) | $ 0.09 |
| Olmex H | |
| Olmex H 20+12.5 Tablet (Canon Biotech) | $ 0.09 |
| Olmezest H | |
| Olmezest H 20+12.5 Tablet (Sun Pharmaceutical Industries Ltd.) | $ 0.10 |
| Olmezest H 40+12.5 Tablet (Sun Pharmaceutical Industries Ltd.) | $ 0.16 |
| OLMEZEST H -20 TABLET 1 strip / 10 tablets each (Sun Pharmaceutical Industries Ltd.) | $ 1.25 |
| OLMEZEST H -40 TABLET 1 strip / 10 tablets each (Sun Pharmaceutical Industries Ltd.) | $ 2.07 |
| Olmezest H 20 Tablet (Sun Pharmaceutical Industries Ltd.) | $ 0.13 |
| Olmezest H 40 Tablet (Sun Pharmaceutical Industries Ltd.) | $ 0.23 |
| Olmy H | |
| Olmy H 20+12.5 Tablet (CND (Zydus Cadila Healthcare Ltd)) | $ 0.10 |
| Olmy H 40+12.5 Tablet (CND (Zydus Cadila Healthcare Ltd)) | $ 0.17 |
| OLMY H 12.5 MG/40 MG TABLET 1 strip / 10 tablets each (CND (Zydus Cadila Healthcare Ltd)) | $ 2.67 |
| OLMY H 12.5MG/20MG TABLET 1 strip / 10 tablets each (CND (Zydus Cadila Healthcare Ltd)) | $ 1.66 |
| Olmy R | |
| Olmy R 5+20 Tablet (CND (Zydus Cadila Healthcare Ltd)) | $ 0.09 |
| Olran H | |
| Olran H 40+12.5 Tablet (Research Medicure Pvt. Ltd.) | $ 0.16 |
| Olways H | |
| Olways H 40+12.5 Tablet (Astra Zeneca Pharma India Limited) | $ 0.13 |
| Olways H 20+12.5 Tablet (Astra Zeneca Pharma India Limited) | $ 0.07 |
| OLWAYS H 12.5 MG/20 MG TABLET 1 strip / 10 tablets each (Astra Zeneca Pharma India Limited) | $ 0.79 |
| OLWAYS H 12.5 MG/40 MG TABLET 1 strip / 10 tablets each (Astra Zeneca Pharma India Limited) | $ 1.44 |
| Opril (India) | |
| Opril 5 mg Capsule (Olcare Laboratories) | $ 0.09 |
| Opril 1.25 mg Capsule (Olcare Laboratories) | $ 0.02 |
| Opril 2.5 mg Capsule (Olcare Laboratories) | $ 0.04 |
| OPRIL tab 1.25 mg x 10's (Olcare Laboratories) | $ 0.27 |
| OPRIL tab 2.5 mg x 10's (Olcare Laboratories) | $ 0.46 |
See 3400 substitutes for Odipril H | |
References
- DailyMed. "RAMIPRIL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "AMLODIPINE BESYLATE; HYDROCHLOROTHIAZIDE; OLMESARTAN MEDOXOMIL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "ramipril". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Odipril H are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Odipril H. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
