What is Omidon?
Omidon is a medicine that increases the movements or contractions of the stomach and bowel. Omidon is also used to treat nausea and vomiting caused by other drugs used to treat Parkinson's Disease.
Omidon is to be given only by or under the immediate supervision of your doctor.
Omidon indications
Dyspeptic symptom complex often associated with delayed gastric emptying, gastroesophageal reflux disease (GERD) or esophagitis: Epigastric sense of fullness, feeling of abdominal distention, upper abdominal pain, flatulence (gassiness), eructation (belching), and heartburn.
Short-term treatment of nausea and vomiting of various origins including functional, organic, infectious, diabetic origin, or induced by radiotherapy or medicine therapy. (It is not considered suitable for chronic nausea and vomiting, nor for the routine prophylaxis of postoperative vomiting.)
Treatment of nausea and vomiting induced by dopamine agonists ie, L-dopa and bromocriptine used in Parkinson's disease.
Omidon may also be given as needed, together with paracetamol for the symptomatic treatment of nausea and vomiting associated with migraine.
Uses of Omidon in details
Omidon is used to treat vomiting or nausea caused due to indigestion, diseases or drugs. It is also used to relieve fullness of stomach, belching and heavy bloating, gas and heartburn for a longer period up to 2 weeks.
Omidon description
Omidon is a synthetic anticoagulant and an indanedione derivative. It prevents the formation of active procoagulation factors II, VII, IX, and X, as well as the anticoagulant proteins C and S, in the liver by inhibiting the vitamin K mediated gamma-carboxylation of precursor proteins.
Omidon dosage
It is recommended to take oral Omidon before meals. If taken after meals, absorption of the drug is somewhat delayed.
Adults and Adolescents >12 years and weighing ≥35 kg: Tablets: One to two 10-mg tablet 3-4 times/day, with a maximum daily dose of 8 tablets (80 mg).
Oral Suspension:
10-20 mL (of oral susp containing Omidon 1 mg/mL) 3-4 times/day, with a maximum daily dose of 80 mL.Infants and Children: 0.25-0.5 mg/kg 3-4 times/day with a maximum daily dose of 2.4 mg/kg (but do not exceed 80 mg/day).
Tablets are unsuitable for use in children weighing <35 kg.
Oral Suspension:
0.25-0.5 mg/kg 3-4 times/day with a maximum dose of 2.4 mg/kg (not exceeding 80 mL).Omidon interactions
The concomitant administration of Omidon with phenothiazines, butyrophenones and rauwolfia alkaloids may induce the endocrine disturbances or extrapyramidal disorders. If necessary, monitored carefully and administered cautiously.
Should be administered cautiously in patients receiving digitalis preparations.
The concomitant administration of Omidon with anticholinergic agents may compromise the beneficial effects of Omidon because of depressing the promoting action of gastrointestinal motility.
Theologically, Omidon may have an effect on the absorption of oral preparations, especially slow-releasing or enteric-coated preparations because of increasing gastric motility. But in patients stabilized with digoxin or acetaminophen, the concomitant administration of Omidon had no effect on plasma concentration of these drugs.
It is not reported that Omidon enhances the effect of neuroleptics.
Omidon inhibits peripheral adverse reactions eg, dyspepsia, nausea, vomiting, induced by dopamine agonist (eg, bromocriptine, levodopa), but has no effect on central nervous system.
As the concomitant administration of Omidon with antacids or acid secretion inhibitors lowers biologic activity of Omidon, these drugs should not be used together.
The actions of Omidon on gastrointestinal function may be antagonised by antimuscarinics and opioid analgesics.
Omidon side effects
See also:
What are the possible side effects of Omidon?
Clinical Trial Data: The safety of Omidon was evaluated in 1221 patients with gastroparesis, dyspepsia, gastro-oesophageal reflux disorder (GERD) or other related conditions in 45 clinical trials included in the safety database. All patients were ≥15 years and received at least 1 dose of oral Omidon (Omidon base). Slightly fewer than one-half (553/1221) of patients were diabetic. The median total daily dose was 80 mg (range 10-160 mg), with 230 patients receiving a dose >80 mg. Median duration of exposure was 56 days (range 1-2248 days).
Adverse drug reactions (ADRs) reported by ≥1% of patients treated with oral Omidon in these 45 clinical trials (n=1221) are the following: Psychiatric Disorders: Depression (2.5%), anxiety (1.6%), decreased libido/loss of libido (1.5%).
Nervous System Disorders: Headache (5.6%), somnolence (2.5%), akathisia (1%).
Gastrointestinal Disorders: Diarrhoea (5.2%).
Skin and Subcutaneous Tissue Disorders: Rash (2.8%), pruritus (1.7%).
Reproductive System and Breast Disorders: Breast enlargement/gynaecomastia (5.3%), breast tenderness (4.4%), galactorrhoea (3.3%), amenorrhoea (2.9%), breast pain (2.3%), irregular menstruation (2%), lactation disorder (1.6%).
General Disorders and Administration Site Conditions: Asthenia (1.9%).
ADRs that occurred in <1% of Omidon-treated patients in the 45 clinical trials (n=1221) are the following: Immune System Disorders: Hypersensitivity (0.2%).
Skin and Subcutaneous Disorders: Urticaria (0.7%).
Reproductive System and Breast Disorders: Breast discharge (0.8%), breast swelling (0.5%).
Dry mouth has been reported with over-the-counter use of Omidon.
Post-Marketing: In addition to the adverse effects reported during clinical studies and previously mentioned, the following adverse drug reactions provided the frequencies according to the following convention: Very common (≥1/10), common (≥1/100 and <1/10); uncommon (≥1/1000 and <1/100); rare (≥1/10,000 and <1/1000); very rare (<1/10,000, including isolated reports).
The following ADRs are presented by frequency category based on spontaneous reporting rates: Immune System Disorders: Very Rare: Anaphylactic reactions (including anaphylactic shock).
Psychiatric Disorders: Very Rare: Agitation, nervousness.
Nervous System Disorders: Very Rare: Extrapyramidal disorder, convulsion.
Cardiac Disorders: Very Rare: Sudden cardiac death*, serious ventricular arrhythmias*.
Skin and Subcutaneous Tissue Disorders: Very Rare: Angioedema.
Renal and Urinary Disorders: Very Rare: Urinary retention.
Investigations: Very Rare: Abnormal liver function test; increased blood prolactin.
Note: *Based on epidemiology data (as follows).
As the hypophysis is outside the blood-brain barrier, Omidon may cause an increase in prolactin levels. In rare cases, this hyperprolactinaemia may lead to neuro-endocrinological side effects eg, galactorrhoea, gynaecomastia and amenorrhoea.
Extrapyramidal disorder occurs primarily in neonates and infants.
Other central nervous system-related effects of convulsion and agitation are also reported primarily in infants and children.
An increase in the risk of serious ventricular arrhythmias and sudden cardiac death has been reported in some epidemiology studies. Due to the limitations of these data, risk factors and the exact frequency of these adverse reactions could not be defined.
Omidon contraindications
Hypersensitivity to Omidon or any ingredient of Omidon.
If patients are taking oral ketoconazole, fluconazole, voriconazole, erythromycin, clarithromycin, telithromycin, amiodarone, selective serotonin reuptake inhibitors, HIV protease inhibitors, calcium antagonists which can increase plasma concentrations of Omidon, leading to a prolonged QTc interval. These medicines can increase plasma concentrations of Omidon leading to a prolonged QTc interval. Patients with long QT syndrome develop a very fast heart rhythm disturbance leading to a sudden loss of consciousness.
Gastrointestinal hemorrhage (bleeding), obstruction, perforation or conditions where gastrointestinal stimulation or movements may be dangerous.
Prolactin-releasing pituitary tumor (prolactinoma).
Active ingredient matches for Omidon:
Domperidone in Bangladesh.
List of Omidon substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Omid DM | |
| Omid DM 20+10 Capsule (Phoenix Pharmaceuticals.) | $ 0.07 |
| Omidon D (Bangladesh) | |
| Omidor D | |
| Omidor D 20+10 Capsule (Adore Healthcare) | $ 0.06 |
| Omig DM | |
| Omig DM 20+10 Tablet (Rass Healthcare) | $ 0.06 |
| Omilee D | |
| Omilee D 20+10 Capsule (Wintech Pharmaceuticals) | $ 0.05 |
| Omipace D | |
| Omipace D 20+10 Capsule (Ratchet Biotech Pvt. Ltd.) | $ 0.05 |
| OMIPACE D 10MG/20MG CAPSULE 1 strip / 10 capsules each (Ratchet Biotech Pvt. Ltd.) | $ 0.54 |
| Omipace D Capsule (Ratchet Biotech Pvt. Ltd.) | $ 0.05 |
| Omiplas D | |
| Omiplas D 20+10 Tablet (Plasmid Health Care Pvt. Ltd.) | $ 0.07 |
| Omiplus | |
| Omiplus 20+10 Capsule (Pharma Synth Formulations Ltd.) | $ 0.05 |
| Omiprex D | |
| Omiprex D 20+10 Capsule (Kentreck Labs Pvt Ltd.) | $ 0.05 |
| OMIPREX D 10 MG/20 MG CAPSULE 1 strip / 10 capsules each (Kentreck Labs Pvt Ltd.) | $ 0.12 |
| Omiprex D 10 mg/20 mg Capsule (Kentreck Labs Pvt Ltd.) | $ 0.01 |
| Omisal D | |
| Omisal D 20+10 Capsule (Salvo Healthcare Pvt Ltd) | $ 0.05 |
| Omisun D | |
| Omisun D 20+10 Capsule (Sungrace Pharma Pvt. Ltd.) | $ 0.05 |
| Omitec D | |
| Omitec D 20+10 Capsule (Retec Formulations Pvt. Ltd.) | $ 0.07 |
| Omitop DM | |
| Omitop DM 20+10 Tablet (Ultramark Healthcare Pvt Ltd.) | $ 0.05 |
| Omium D | |
| Omium D 20+10 Capsule (Symbiosis Labs (P) Ltd.) | $ 0.06 |
| Omiup D | |
| Omiup D 20+10 Capsule (UPS Healthcare) | $ 0.03 |
| Omivan D | |
| Omivan D 20+10 Capsule (Malcom Pharmaceuticals) | $ 0.06 |
| Omix D | |
| Omix D 20+10 Capsule (Merril Pharma Pvt. Ltd.) | $ 0.05 |
| Omiz D | |
| Omiz D 20+10 Capsule (Jarson Pharmaceuticals) | $ 0.04 |
| Omizol D | |
| Omizol D 20+10 Blossoms Biologicals Capsule (Blossoms Biologicals) | $ 0.06 |
| Omizol D 20+10 Capsule (Blossoms Biologicals) | $ 0.12 |
| Omkair D | |
| Omkair D 20+10 Capsule (PDC Healthcare) | $ 0.06 |
| Omkar D | |
| Omkar D 10+10 Capsule (Techyon Biotech (P) Limited) | $ 0.05 |
| Omkar DSR | |
| Omkar DSR 10+30 Capsule (Techyon Biotech (P) Limited) | $ 0.08 |
| Omlek D | |
| Omlek D 10+20 Capsule (Lekar Health Care Ltd) | $ 0.05 |
| OMLEK D 10MG/20MG CAPSULE 1 strip / 10 capsules each (Lekar Health Care Ltd) | $ 0.68 |
| Omlek D Capsule (Lekar Health Care Ltd) | $ 0.07 |
| Omlin D | |
| Omlin D 20+10 Capsule (Ampus Life Sciences Ltd) | $ 0.06 |
| OMLIN D 10MG/20MG CAPSULE 1 strip / 10 capsules each (Ampus Life Sciences Ltd) | $ 0.54 |
| Omlin D Capsule (Ampus Life Sciences Ltd) | $ 0.05 |
| Omlink D | |
| Omlink D 20+10 Capsule (Lincoln Pharmaceuticals Ltd) | $ 0.06 |
| OMLINK D 10MG/20MG CAPSULE 1 strip / 10 capsules each (Lincoln Pharmaceuticals Ltd) | $ 0.36 |
| Omlink D Capsule (Lincoln Pharmaceuticals Ltd) | $ 0.04 |
| Omlo D | |
| Omlo D 20+10 Capsule (Globus Remedies Ltd) | $ 0.06 |
| Omni DM | |
| Omni DM 20+10 Capsule (Reco Drugs) | $ 0.02 |
| Omocid Plus | |
| Omocid Plus 20+10 Capsule (Om Biotec) | $ 0.05 |
| Omoffin D | |
| Omoffin D 20+10 Capsule (Boffin Biotech Pvt Ltd) | $ 0.05 |
| Omon D | |
| Omon D 20+10 Capsule (Maya Drugs & Antibiotics) | $ 0.05 |
| Omore D | |
| Omore D 20+10 Tablet (Biomax Biotechnics) | $ 0.07 |
See 2682 substitutes for Omidon | |
References
- PubChem. "domperidone". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "domperidone". http://www.drugbank.ca/drugs/DB01184 (accessed September 17, 2018).
- DTP/NCI. "domperidone: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Omidon are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Omidon. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
1 consumer reported useful
Was the Omidon drug useful in terms of decreasing the symptom or the disease?According to the reports released by ndrugs.com website users, the below mentioned percentages of users say the drug is useful / not useful to them in decreasing their symptoms/disease. The usefulness of the drug depends on many factors, like severity of the disease, perception of symptom, or disease by the patient, brand name used [matters only to a certain extent], other associated conditions of the patient. If the drug is not effective or useful in your case, you need to meet the doctor to get re-evaluated about your symptoms/disease, and he will prescribe an alternative drug.
| Users | % | ||
|---|---|---|---|
| Not useful | 1 | 100.0% | |
Consumer reported price estimates
No survey data has been collected yet1 consumer reported time for results
To what extent do I have to use Omidon before I begin to see changes in my health conditions?As part of the reports released by ndrugs.com website users, it takes > 3 month and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Omidon. To get the time effectiveness of using Omidon drug by other patients, please click here.
| Users | % | ||
|---|---|---|---|
| > 3 month | 1 | 100.0% | |
22 consumers reported age
| Users | % | ||
|---|---|---|---|
| 16-29 | 9 | 40.9% | |
| 1-5 | 4 | 18.2% | |
| > 60 | 3 | 13.6% | |
| 6-15 | 3 | 13.6% | |
| 46-60 | 2 | 9.1% | |
| 30-45 | 1 | 4.5% | |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
