Orcolax Uses

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What is Orcolax?

Orcolax (Orcolax) is a laxative that stimulates bowel movements.

Orcolax is used to treat constipation or to empty the bowels before surgery, colonoscopy, x-rays, or other intestinal medical procedure.

Orcolax tablets generally produce a bowel movement in 6 to 12 hours. Orcolax suppositories generally produces bowel movements in 15 minutes to 1 hour.

Orcolax indications

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Orcolax is a laxative that stimulates bowel movements.

Orcolax is used to treat constipation or to empty the bowels before surgery, colonoscopy, x-rays, or other intestinal medical procedure.

How should I use Orcolax?

Use Orcolax enema as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Ask your health care provider any questions you may have about how to use Orcolax enema.

Uses of Orcolax in details

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Orcolax is used to treat constipation. It may also be used to clean out the intestines before a bowel examination/surgery. Orcolax is known as a stimulant laxative. It works by increasing the movement of the intestines, helping the stool to come out.

How to use Orcolax

Take this medication by mouth as directed by your doctor. If you are self-treating, follow all directions on the product package. If you are uncertain about any of the information, ask your doctor or pharmacist.

Swallow this medication whole. Do not crush, chew, or break the tablet or take it within 1 hour of antacids, milk, or milk products. Doing so can destroy the coating on the tablet and may increase the risk of stomach upset and nausea.

Dosage is based on your age, medical condition, and response to treatment. Do not increase your dose or take this drug more often than directed. Do not take this medication for more than 7 days unless directed by your doctor. Serious side effects may occur with overuse of this medication.

It may take 6 to 12 hours before this medication causes a bowel movement. Tell your doctor if your condition persists or worsens, or if bleeding from the rectum occurs. If you think you may have a serious medical problem, seek immediate medical attention.

Orcolax description

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Orcolax may also contain the following excipients: Tablet: Lactose monohydrate, dried and undried maize starch, glycerol, magnesium stearate, crystallized sugar, talc, acacia, titanium dioxide, methacrylic acid-methyl methacrylate copolymer (1:1) and (1:2), PEG 6000, ferric oxide yellow (E172), beeswax white, carnauba wax, dibutyl phthalate, p-hydroxybenzoic acid methyl ester, p-hydroxybenzoic acid propyl ester. Suppositories: Hard fat Witepsol W45, E76.

Orcolax is 4,4'-diacetoxy-diphenyl-(pyridyl-2)-methane.

Orcolax dosage

Orcolax Dosage

Applies to the following strength(s): 5 mg; 10 mg

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Bowel Preparation

5 to 15 mg (1 to 3 tablets) orally once a day as needed or

10 mg (1 suppository) rectally once a day as needed or

10 mg rectal liquid once a day as needed.

Usual Adult Dose for Constipation

5 to 15 mg (1 to 3 tablets) orally once a day as needed or

10 mg (1 suppository) rectally once a day as needed or

10 mg rectal liquid once a day as needed.

Renal Dose Adjustments

No adjustment recommended.

Caution is recommended when using Orcolax enemas containing monobasic or dibasic sodium phosphate in patients with impaired renal function or where colostomy exists as hypocalcemia, hyperphosphatemia, hypernatremia, and acidosis may occur.

Liver Dose Adjustments

No adjustment recommended

Dialysis

No adjustment recommended

Other Comments

Alleviation of constipation can be expected within 8 to 12 hours if taken at bedtime or within 6 hours if taken during waking hours.

More about Orcolax

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Orcolax interactions

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What other drugs will affect Orcolax?

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Antacids: May diminish the therapeutic effect of Orcolax. Antacids may cause the delayed-release Orcolax tablets to release drug prior to reaching the large intestine. Gastric irritation and/or cramps may occur. Management: Antacids should not be used within 1 hour before Orcolax administration. Consider therapy modification

Dichlorphenamide: Laxatives may enhance the hypokalemic effect of Dichlorphenamide. Monitor therapy

Polyethylene Glycol-Electrolyte Solution: Orcolax may enhance the adverse/toxic effect of Polyethylene Glycol-Electrolyte Solution. Monitor therapy

Orcolax side effects

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What are the possible side effects of Orcolax?

Applies to Orcolax: oral tablets delayed-release, rectal suppositories, rectal suspension

Side effects include:

Some degree of abdominal discomfort, nausea, cramps, griping, and/or faintness with therapeutic doses.

Diarrhea, GI irritation, and fluid and electrolyte depletion.

Gastric irritation and the possibility of vomiting if enteric coating of tablets is disrupted.

Rectal administration of Orcolax (the active ingredient contained in Orcolax Uniserts) suspensions or suppositories may cause irritation and a sensation of burning of the rectal mucosa and mild proctitis.

Hepatotoxicity if sufficient tannic acid is absorbed from Orcolax tannex.

Orcolax contraindications

See also:
What is the most important information I should know about Orcolax?

Hypersensitivity to any component.

- Colopathies organic inflammatory (ulcerative colitis, Crohn’s disease...).

- Subocclusif occlusive syndrome.

- Abdominal pain syndromes of unknown cause.

- States of severe dehydration with electrolyte depletion.

RECOMMENDED:

- Pregnancy: there is no reliable data on teratogenesis in animals. Clinically, there is currently no adequate data to evaluate a possible effect of malformation or Orcolax fetotoxic when administered during pregnancy. Consequently, the use of Orcolax is not recommended during pregnancy. This item does not recommend a systematic argument for abortion, but leads to an attitude of caution and a prenatal care oriented.

- Breast-feeding: Because it passes through breast milk, the use of Orcolax is discouraged.

- Concomitant use not recommended: medication torsade de pointes (amiodarone, astemizole, bepridil, bretylium, disopyramide, erythromycin IV, halofantrine, pentamidine, quinidine, sparfloxacin, sotalol, sultopride, terfenadine, vincamine).



Active ingredient matches for Orcolax:

Bisacodyl


Unit description / dosage (Manufacturer)Price, USD
Orcolax 5 mg Tablet$ 0.01

List of Orcolax substitutes (brand and generic names):

NOVOLAX oral susp 5 g x 5 mL x 100ml (MDC)$ 0.60
Picosulu 3 mg
Suppositories; Rectal; Bisacodyl 10 mg
Tablet; Oral; Bisacodyl 5 mg
PMS-bisacodyl tablet 5 mg (Pharmascience Inc (Canada))
PMS-bisacodyl suppository 10 mg (Pharmascience Inc (Canada))
Tablet, Film-Coated; Oral; Bisacodyl 5 mg / Solution; Oral; Sodium Phosphate Dibasic Anhydrous 9.54 g; Sodium Phosphate Monobasic Anhydrous 41.74 g / 100 ml (Codali)
Tablet, Film-Coated; Oral; Bisacodyl 5 mg / Solution; Oral; Sodium Phosphate Dibasic Anhydrous 9.54 g; Sodium Phosphate Monobasic Anhydrous 41.74 g / 100 ml
Tablet, Film-Coated; Oral; Bisacodyl 5 mg / Solution; Oral; Sodium Phosphate Dibasic Anhydrous 9.54 g; Sodium Phosphate Monobasic Anhydrous 41.74 g / 100 ml
Dragee; Oral; Bisacodyl 5 mg (Generis)
Suppositories; Rectal; Bisacodyl 10 mg (Generis)
Dragee, Gastro-Resistant; Oral; Bisacodyl 5 mg (Berlin-chemie)
Suppositories; Rectal; Bisacodyl 10 mg (Berlin-chemie)
Suppositories; Rectal; Bisacodyl 10 mg
Ratio-bisacodyl suppository 10 mg (Teva Canada Limited (Canada))
S.L. Laxative 5 mg x 1's
Saflax 5mg TAB / 100 (Psyco Remedies.)$ 0.96
5 mg x 100's (Psyco Remedies.)$ 0.96
Saflax 5 mg Tablet (Psyco Remedies.)$ 0.01
SAFLAX tab 5 mg x 10's (Psyco Remedies.)$ 0.10
Suppositories; Rectal; Bisacodyl 10 mg
Suppositories; Rectal; Bisacodyl 10 mg (Pharmascience)
Tablet; Oral; Bisacodyl 5 mg (Pharmascience)
Dragee; Oral; Bisacodyl 5 mg
Dragee, Gastro-Resistant; Oral; Bisacodyl (Stada)

References

  1. DailyMed. "BISACODYL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "bisacodyl". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
  3. DrugBank. "Bisacodyl". http://www.drugbank.ca/drugs/DB09020 (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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