What is Oxwalt?
Oxwalt is a germicidal mouthwash that reduces bacteria in the mouth.
Oxwalt oral rinse is used to treat gingivitis (swelling, redness, bleeding gums). Oxwalt is usually prescribed by a dentist.
Oxwalt oral rinse is not for treating all types of gingivitis. Use the medication only to treat the condition your dentist prescribed it for. Do not share this medication with another person, even if they have the same gum symptoms you have.
Oxwalt may also be used for purposes not listed in this medication guide.
Oxwalt indications
Oxwalt® (Oxwalt
Oral Rinse USP, 0.12%) is indicated for use between dental visits as part of a professional program for the treatment of gingivitis as characterized by redness and swelling of the gingivae, including gingival bleeding upon probing. Oxwalt® has not been tested among patients with acute necrotizing ulcerative gingivitis (ANUG). For patients having coexisting gingivitis and periodontitis, see PRECAUTIONS.
How should I use Oxwalt?
Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Rinse your mouth with Oxwalt twice daily after brushing your teeth.
Measure your dose using the cup provided with the medication. Swish the medicine in your mouth for at least 30 seconds, then spit it out. Do not swallow the mouthwash.
Do not add water to the oral rinse. Do not rinse your mouth with water or other mouthwashes right after using Oxwalt.
Oxwalt may leave an unpleasant taste in your mouth. Do not rinse your mouth to remove this taste after using the medication. You may rinse the medicine away and reduce its effectiveness.
Use this medication for the full prescribed length of time. Your symptoms may improve before your gingivitis is completely cleared. Oxwalt will not treat a viral or fungal infection such as cold sores, canker sores, or oral thrush (yeast infection).
Visit your dentist at least every 6 months for preventive tooth and gum care.
Store Oxwalt at room temperature away from moisture and heat.
Uses of Oxwalt in details
Use: Labeled Indications
Gingivitis:
Oral rinse: Antimicrobial dental rinse for gingivitis treatment
Periodontitis: Periodontal chip: Adjunctive therapy to scaling and root planning procedures to reduce pocket depth in patients with periodontitis
Off Label Uses
Medication-related osteonecrosis of the jaw (MRONJ), adjunctive therapy:
Oral rinse:
Based on a position paper by the American Association of Maxillofacial Surgeons (AAOMS), Oxwalt oral rinse is an effective and recommended adjunctive treatment strategy in the management of medication-related osteonecrosis of the jaw (MRONJ) (stage 1 and above [eg, patients with exposed and necrotic bone or fistulae that probes to bone]).
Oropharyngeal decontamination to reduce the risk of ventilator-associated or hospital-acquired pneumonia, Cardiac surgical patients:
Oral rinse:
Data from a prospective, randomized, double-blind, placebo-control trial and a prospective, randomized, case-controlled trial in patients undergoing coronary artery bypass grafting, valve, or other open heart surgical procedures who received Oxwalt 0.12% oral rinse during the perioperative period showed a decreased rate in hospital-acquired pneumonia. However, the trials used in both meta-analyses were heterogeneous and included patients in a variety of settings (eg, cardiothoracic, general ICU, mixed medical-surgical ICU, trauma ICU). The trials also displayed significant variability with Oxwalt treatment regimens. Oxwalt concentration varied from 0.12%, 0.2%, or 2% across studies. Frequency of administration, Oxwalt dosage form (oral rinse, gel, paste, foam), and technique of application also varied across studies. In the US, Oxwalt for use in the oral cavity is commercially available only as 0.12% solution. Additional trials may be necessary to further define the role of Oxwalt oral rinse in this condition.
Oxwalt description
Each chip contains chlorhexidine gluconate 2.5 mg in a biodegradable matrix of hydrolyzed gelatin (cross-linked with glutaraldehyde).
Oxwalt also contains glycerin and purified water as excipients.
Oxwalt, an antimicrobial agent, is 1, 1'-hexamethylenebis [5-(p-chlorophenyl)biguanide] di-D-gluconate. Molecular Formula: C22H30Cl2N10·2C6H12O7. Molecular Weight: 897.8.
Oxwalt dosage
Oxwalt Dosage
Generic name: Oxwalt 1.2mg in 1mL
Dosage form: mouthwash
The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.
Oxwalt therapy should be initiated directly following a dental prophylaxis. Patients using Oxwalt should be reevaluated and given a thorough prophylaxis at intervals no longer than six months. Recommended use is twice daily oral rinsing for 30 seconds, morning and evening after toothbrushing. Usual dosage is 15ml (marked in cap) of undiluted Oxwalt. Patients should be instructed to not rinse with water or other mouthwashes, brush teeth or eat immediately after using Oxwalt. Oxwalt is not intended for ingestion and should be expectorated after rinsing.
More about Oxwalt (Oxwalt topical)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Support Group
- Pricing & Coupons
- En Espanol
- 2 Reviews - Add your own review/rating
- Generic Availability
Consumer resources
- Oxwalt solution
- Oxwalt oral rinse
- Oxwalt (Advanced Reading)
- Other brands: Hibiclens, Betasept, Oxwalt, ChloraPrep One-Step, More (9) »
Professional resources
- Oxwalt (FDA)
- Oxwalt topical (AHFS Monograph)
Related treatment guides
- Gingivitis
- Mucositis
- Periodontitis
Oxwalt interactions
See also:
What other drugs will affect Oxwalt?
Oxwalt is incompatible with the soap, and detergents containing anionic group (saponins, sodium lauryl sulfate, sodium carboxymethyl cellulose).
Oxwalt Pharmaniaga is compatible with any medication containing cationic group (cetrimonium bromide, benzalkonium chloride).
Oxwalt side effects
See also:
What are the possible side effects of Oxwalt?
The most common side effects associated with Oxwalt oral rinses are (1) an increase in staining of teeth and other oral surfaces, (2) an increase in calculus formation; and (3) an alteration in taste perception; see WARNINGS and PRECAUTIONS.
Oral irritation and local allergy-type symptoms have been spontaneously reported as side effects associated with the use of Oxwalt rinse.
The following oral mucosal side effects were reported during placebo-controlled adult clinical trials: aphthous ulcer, grossly obvious gingivitis, trauma, ulceration, erythema, desquamation, coated tongue, keratinization, geographic tongue, mucocele, and short frenum. Each occurred at a frequency of less than 1.0%.
Among post marketing reports, the most frequently reported oral mucosal symptoms associated with Oxwalt oral rinse are stomatitis, gingivitis, glossitis, ulcer, dry mouth, hypesthesia, glossal edema, and paresthesia.
Minor irritation and superficial desquamation of the oral mucosa have been noted in patients using Oxwalt oral rinse.
There have been cases of parotid gland swelling and inflammation of the salivary glands (sialadenitis) reported in patients using Oxwalt oral rinse.
Oxwalt contraindications
See also:
What is the most important information I should know about Oxwalt?
You should not use this medication if you are allergic to Oxwalt.
If you have periodontal disease, you may need special treatments while you are using Oxwalt.
Oxwalt oral rinse is not for treating all types of gingivitis. Use the medication only to treat the condition your dentist prescribed it for. Do not share this medication with another person, even if they have the same gum symptoms you have.
Do not give this medication to a child or teenager without a doctor's advice.
Do not add water to Oxwalt oral rinse. Do not rinse your mouth with water or other mouthwashes right after using Oxwalt.
Avoid eating, drinking, or brushing your teeth just after using this medication.
Do not use any other mouthwash unless your doctor has told you to.
Oxwalt can stain teeth, dentures, tooth restorations, your tongue, or the inside of your mouth. Talk with your dentist about ways to remove staining from these surfaces. Stains may be harder to remove from false teeth that have scratches in their surfaces.
Visit your dentist at least every 6 months for preventive tooth and gum care.
Active ingredient matches for Oxwalt:
Chlorhexidine gluconate in India.
| Unit description / dosage (Manufacturer) | Price, USD |
| 0.2 % w/v x 100ml | $ 0.46 |
| Oxwalt 0.2% w/v M-WASH / 100ml | $ 0.46 |
| Oxwalt Mouth/Throat 100 ml Mouth Wash/Gargle | $ 0.46 |
| OXWALT mouthwash 0.2 % w/v x 100ml (Edward) | $ 0.46 |
| Oxwalt 0.2% w/v M-WASH / 100ml | $ 0.46 |
List of Oxwalt substitutes (brand and generic names): | |
| Otsol (Bangladesh) | |
| Parmason (Taiwan) | |
| Parmason 1 g | |
| Parmason 3 g | |
| Parmason 5 g | |
| Parmason 10 g | |
| Parmason 15 g | |
| Parmason 20 g | |
| Parmason 500 g | |
| Parmason 1 kg | |
| Parmason Gargle (Taiwan) | |
| Parmason Gargle 2 mg/1 mL x 200 mL | |
| Parodium (Argentina) | |
| Gel; Dental; Chlorhexidine Gluconate 0.02%; Formaldehyde 0.1%; Rhubarb 0.2% (Pierre fabre) | |
| Parodongyl (Germany) | |
| Paroex | |
| Solution; Local Oral; Chlorhexidine Gluconate 0.12% (Pharmadent) | |
| Paroex rinse 1.2 mg/mL (Pharmadent) | |
| Paroex 0.12% (France) | |
| Paroex Oral Rinse | |
| Parosept (Sweden) | |
| Pearlcare (India) | |
| Pearlcare 1% w/v M-WASH / 100ml (Pharma Synth) | $ 0.27 |
| 1 % w/v x 100ml (Pharma Synth) | $ 0.27 |
| PEARLCARE mouthwash 1 % w/v x 100ml (Pharma Synth) | $ 0.27 |
| Peefresh (India) | |
| Peefresh Chlorhexidine 0.2 % w/v, Sodium fluoride 0.05 % w/v, Zinc chloride 0.09 % w/v. M-WASH / 100ml (Peerage) | $ 0.46 |
| 100ml (Peerage) | $ 0.46 |
| PEEFRESH mouthwash 100ml (Peerage) | $ 0.46 |
| Pelwash (India) | |
| Pelwash 0.2% M-WASH / 100ml (Pax Healthcare) | $ 0.46 |
| 0.2 % w/v x 100ml (Pax Healthcare) | $ 0.46 |
| PELWASH mouthwash 0.2 % w/v x 100ml (Pax Healthcare) | $ 0.46 |
| Pendin (India) | |
| Pendin Chlorhexidine 0.2 % w/w, Sodium benzoate 0.2 % w/w. M-WASH / 100ml (Vensat) | $ 0.42 |
| 100ml (Vensat) | $ 0.42 |
| PENDIN mouthwash 100ml (Vensat) | $ 0.42 |
| Percyl (Italy) | |
| Perichlor (Canada) | |
| Liquid; Buccal; Chlorhexidine Gluconate 0.12% | |
| Perichlor liquid 0.12 % (Pharmascience Inc (Canada)) | |
| Perident (Chile) | |
| Peridex | |
| Liquid; Buccal; Chlorhexidine Gluconate 0.12% (Procter & gamble) | |
| Mouthwash; Buccal; Chlorhexidine Gluconate 0.12% (Procter & gamble) | |
| 118 milliliter in 1 bottle, plastic (Procter & gamble) | |
| 1893 milliliter in 1 bottle, pump (Procter & gamble) | |
| 473 milliliter in 1 bottle, plastic (Procter & gamble) | |
| Solution; Dental; Chlorhexidine Gluconate 0.12% (Procter & gamble) | |
| Peridex rinse 1.2 mg/mL (Procter & gamble) | |
| Peridex oral rinse | |
| Liquid; Buccal; Chlorhexidine Gluconate 0.12% | |
| Mouthwash; Buccal; Chlorhexidine Gluconate 0.12% | |
See 1883 substitutes for Oxwalt | |
References
- DailyMed. "CHLORHEXIDINE GLUCONATE; ISOPROPYL ALCOHOL: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "chlorhexidine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "chlorhexidine". http://www.drugbank.ca/drugs/DB00878 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Oxwalt are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Oxwalt. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
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Information checked by Dr. Sachin Kumar, MD Pharmacology
