Painex indications
Painex is a drug used for joint and muscular pain.
Painex description
Painex is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain.
Painex dosage
When Painex administered orally for replacement therapy in adults the initial dose is 20-30 mg, maintenance dose is 10.5 mg / day. If necessary, the initial dose is may be 15-100 mg / day, the maintenance one is 5-15 mg / day. The daily dose should be reduced gradually. For children the starting dose is 1-2 mg / kg in 4-6 receptions, the maintenance one is 300-600 mg / kg / day.
For IM or IV dose administration the multiplicity and duration of application are determined individually.
When intra-articular administration in large joints it used a dose of 25-50 mg, for medium-sized joints - 10-25 mg for small joints - 5-10 mg. For the introduction of infiltration into the tissues depending on disease severity and magnitude of the defeat use doses from 5 mg to 50 mg.
Painex used topically in ophthalmology 3 times / day, course of treatment is no more than 14 days; in dermatology - 1-3 times / day.
Painex interactions
When this drug applied simultaneously with:
- digoxin slightly increased concentration of digoxin in plasma.
- itraconazole greatly increases the concentration of atorvastatin in plasma, apparently due to inhibition of itraconazole its metabolism in the liver that occurs with the participation of isoenzyme CYP3A4; increased risk of myopathy.
- colestipol may decrease the concentration of atorvastatin in plasma, with lipid-lowering effect is enhanced.
- antacids containing magnesium hydroxide and aluminum hydroxide, reduce the concentration of atorvastatin by approximately 35%.
- cyclosporine, fibrates (including gemfibrozil), azole antifungals derivatives, nicotinic acid increases the risk of myopathy.
- erythromycin, clarithromycin moderately increased concentrations of atorvastatin in plasma, increases the risk of myopathy.
- ethinyl estradiol, norethisterone (norethindrone) slightly increases the concentration of ethinyl estradiol, norethisterone and (norethindrone) in blood plasma.
- protease inhibitors increases the concentration of Eto in plasma, as protease inhibitors are inhibitors of the CYP3A4 isoenzyme.
Diltiazem, verapamil, isradipine inhibit isoenzyme CYP3A4, which participates in the metabolism of Eto, so that while the use of these calcium channel blockers may increase the concentration of atorvastatin in plasma and increased risk of myopathy.
Painex side effects
Endocrine system: menstrual irregularities, suppression of adrenal function, Itsenko-Cushing's syndrome, suppression of pituitary-adrenal system, reduced tolerance to carbohydrates, steroid diabetes, or a manifestation of latent diabetes, growth retardation in children, delayed sexual development in children.
Digestive system: nausea, vomiting, steroid ulcer and duodenal ulcer, pancreatitis, esophagitis, bleeding and perforation of the gastrointestinal tract, increased or decreased appetite, flatulence, hiccups. In rare cases - elevated liver transaminases and alkaline phosphatase.
Metabolism: the negative nitrogen balance due to protein catabolism, increased excretion of calcium from the body, hypocalcemia, weight gain, increased sweating.
Cardiovascular system: the loss of potassium, hypokalemic alkalosis, arrhythmia, bradycardia (up to cardiac arrest); steroid myopathy, heart failure (the development or worsening of symptoms), ECG changes typical of hypokalemia, increased blood pressure, hypercoagulability, thrombosis. In patients with acute myocardial infarction - the spread of necrosis, slowing the formation of scar tissue that can lead to rupture of the heart muscle.
Musculoskeletal system: slowing growth and ossification processes in children (premature closure of epiphyseal growth zones) and osteoporosis (very rarely - pathological fractures, aseptic necrosis of the humeral head and femoral), rupture of tendons of muscles, muscle weakness, steroid myopathy, loss of muscle mass (atrophy).
CNS: headache, increased intracranial pressure, delirium, disorientation, euphoria, hallucinations, manic-depressive psychosis, depression, nervousness or anxiety, insomnia, dizziness, vertigo, pseudotumor cerebellum, and seizures.
Vision: the rear subcapsular cataracts, increased intraocular pressure (with the possible damage to the optic nerve), trophic changes of the cornea, exophthalmos, the propensity to develop secondary infections (bacterial, fungal, viral).
Dermatological reactions: petechiae, ecchymosis, thinning and fragility of the skin, hyper- or hypopigmentation, acne, stretch marks, susceptibility to the development of pyoderma and candidiasis.
Reactions due to immunosuppressive effect: slow process of regeneration, reduced resistance to infections.
For parenteral administration: in rare cases of anaphylactic and allergic reactions, hyper- or hypopigmentation, atrophy of skin and subcutaneous tissue, exacerbation after intrasinovialnogo applications such as Charcot arthropathy, sterile abscesses, when injected into pockets on the head - blindness.
Painex contraindications
Active ingredient matches for Painex:
Etofenamate in Bangladesh, Portugal, Turkey.
Acetaminophen/Caffeine/Codeine Phosphate/Doxylamine Succinate
Diclofenac in Portugal, Turkey.
Diclofenac sodium or diclofenac diethylamine in Portugal.
Tramadol in India.
Unit description / dosage (Manufacturer) | Price, USD |
Tablet; Oral; Aspirin 375 mg; Caffeine Citrate 30 mg; Codeine Phosphate 15 mg | |
Tablet; Oral; Aspirin 375 mg; Caffeine Citrate 30 mg; Codeine Phosphate 30 mg | |
100 mg x 2mlx10 | |
Painex 100mg INJ / 2mlx10 | |
PAINEX inj 100 mg x 2ml (Mint) | |
Painex NA Gel (Arehk Healthcare) | $ 0.66 |
List of Painex substitutes (brand and generic names): | |
Painelief (Thailand) | |
Painelief Cool Gel 1 % x 60 g | |
PAINEX (AREHK) | |
PAINEX / AREHK GEL 1 tube / 30 GM gel each (Arehk Healthcare) | $ 0.66 |
Painex Gele (Portugal) | |
Painkair (India) | |
Painkair 75mg x 3mL INJ / 10 (PDC) | $ 0.96 |
75 mg x 3 mL x 10's (PDC) | $ 0.96 |
PAINKAIR inj 75 mg x 3 mL x 3ml (PDC) | $ 0.10 |
Painout (India) | |
Painout 25mg INJ / 3ml (Ethix HC) | $ 0.08 |
Painout 25mg INJ / 30ml (Ethix HC) | $ 0.18 |
Painout 100mg TAB / 200 (Ethix HC) | |
100 mg x 200's (Ethix HC) | |
PAINOUT tab 100 mg x 10's (Ethix HC) | |
PAINOXOL | |
PAINOXOL 1% W/W GEL 1 tube / 30 GM gel each (GRAF Laboratories Pvt Ltd) | $ 0.63 |
PAINOXOL 25 MG TABLET 1 strip / 10 tablets each (GRAF Laboratories Pvt Ltd) | $ 0.21 |
Painoxol 25mg Tablet (GRAF Laboratories Pvt Ltd) | $ 0.02 |
Panaflex (Singapore) | |
Panaflex 2's (GlaxoSmithKline Consumer Healthcare) | |
Panaflex Neck & Shoulder Pain Relief dermal patch 3's (GlaxoSmithKline Consumer Healthcare) | |
Panaflex Pain Relief dermal patch 2's (GlaxoSmithKline Consumer Healthcare) | |
PanaFlex Extra (Malaysia) | |
PanaFlex Extra 1 % x 30 g (GlaxoSmithKline Consumer Healthcare) | |
PanaFlex Extra topical gel 1% 30 g x 1's (GlaxoSmithKline Consumer Healthcare) | |
Panaflex Max Pain Relief (Hong Kong) | |
PANAMA OINT (India) | |
30g (Mint) | |
Panama Oint Diclofenac 1.16 mg, Methylsalicylate 100 mg, Menthol 50 mg. OINT / 30g (Mint) | |
PANAMA OINT oint 30g (Mint) | |
Panama Oint Diclofenac 1.16 mg, Methylsalicylate 100 mg, Menthol 50 mg. OINT / 30g (Mint) | |
Panamor (South Africa) | |
Parafortan (Ethiopia, Myanmar, Philippines) | |
Parafortan Diclofenac Sodium 25mg INJ / 3ml (Khandelwal) | $ 0.06 |
Parafortan Diclofenac Na 50mg, Paracetamol 500mg TAB / 100 (Khandelwal) | $ 1.99 |
Parafortan / Amp 25 mg/1 mL x 3 mL (Khandelwal) | |
100's (Khandelwal) | $ 1.99 |
Parafortan Diclofenac sodium 50 mg, paracetamol 500 mg. TAB / 100 (Khandelwal) | $ 1.99 |
PARAFORTAN 25MG INJECTION 1 vial / 3 ML injection each (Khandelwal) | $ 0.11 |
PARAFORTAN 50MG/500MG TABLET 1 strip / 10 tablets each (Khandelwal) | $ 0.23 |
PARAFORTAN tab 10's (Khandelwal) | $ 0.20 |
Parafortan 25mg Injection (Khandelwal) | $ 0.04 |
Parafortan Tablet (Khandelwal) | $ 0.02 |
Parafortan INJ (India) | |
Parafortan INJ Diclofenac sodium AMP / 30ml (Khandelwal) | $ 0.60 |
30ml (Khandelwal) | $ 0.60 |
PARAFORTAN INJ inj 25 mg x 1 mL x 30ml (Khandelwal) | $ 0.60 |
PARAFORTAN INJ. | |
PARAFORTAN INJ. Injection / 25mg per ml / 3ml units (Khandelwal Laboratories) | $ 0.06 |
PARAFORTAN INJ. Capsule/ Tablet / 50mg / 10 units (Khandelwal Laboratories) | $ 0.20 |
PARATEL-T (India) | |
100's (Intel Pharma) | $ 5.42 |
Paratel-T Tramadol 37.5 mg, paracetamol325 mg. TAB / 100 (Intel Pharma) | $ 5.42 |
See 12477 substitutes for Painex |
References
- DailyMed. "DICLOFENAC EPOLAMINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "CODEINE SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- DailyMed. "CAFFEINE; ERGOTAMINE TARTRATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Painex are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Painex. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yet1 consumer reported price estimates
Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?The below mentioned numbers have been reported by ndrugs.com website users about whether the Painex drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
Users | % | ||
---|---|---|---|
Not expensive | 1 | 100.0% |
2 consumers reported time for results
To what extent do I have to use Painex before I begin to see changes in my health conditions?As part of the reports released by ndrugs.com website users, it takes 5 days and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Painex. To get the time effectiveness of using Painex drug by other patients, please click here.
Users | % | ||
---|---|---|---|
5 days | 1 | 50.0% | |
2 days | 1 | 50.0% |
13 consumers reported age
Users | % | ||
---|---|---|---|
16-29 | 5 | 38.5% | |
46-60 | 2 | 15.4% | |
30-45 | 2 | 15.4% | |
1-5 | 1 | 7.7% | |
> 60 | 1 | 7.7% | |
< 1 | 1 | 7.7% | |
6-15 | 1 | 7.7% |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology