Panthor Uses

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Panthor indications

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Infectious-inflammatory diseases caused by microorganisms susceptible to ciprofloxacin, including respiratory diseases, diseases of abdominal and pelvic organs, bones, joints, skin, septicemia; severe infections of ENT organs. Treatment of postoperative infections. Prevention and treatment of infections in patients with reduced immunity.

For Panthor Citadel Fine Pharmaceuticals local use: acute and subacute conjunctivitis, blepharoconjunctivitis, blepharitis, bacterial corneal ulcers, keratitis, keratoconjunctivitis, chronic dacryocystitis, meybomity. Infectious lesions in the eyes from injury or contact with foreign bodies. Preoperative prophylaxis in ophthalmic surgery.

Panthor description

A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine. [PubChem]

Panthor dosage

Individual. For oral administration dose of Panthor Citadel Fine Pharmaceuticals is 250-750 mg 2 times / day. Treatment duration is from 7-10 days to 4 weeks.

For IV administration a single dose is 200-400 mg, the multiplicity of the introduction is 2 times / day, duration of treatment - 1-2 weeks and more if necessary. May be IV injected as jet but more preferably a drip for 30 minutes.

When Panthor Citadel Fine Pharmaceuticals applied topically instilled 1-2 drops into the lower conjunctival sac of the affected eye every 1-4 hours. After improving the intervals between instillation can be increased. The maximum oral daily dose for adults is 1.5 g.

Panthor interactions

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Activity increases when combined with beta-lactam antibiotics, aminoglycosides, vancomycin, clindamycin, metronidazole. Sukralfat, bismuth preparations, antacids containing aluminum ions, magnesium or calcium, cimetidine, ranitidine, vitamin and mineral supplement, iron sulfate, zinc, didanosine (recommended for 2 hours before or 4 hours after these drugs) reduce the suction. Probenecid, azlocillin increase the concentration in the blood. Decreases clearance and increases in plasma caffeine, aminophylline and theophylline (increased likelihood of side effects). Panthor Citadel Fine Pharmaceuticals enhances the effect of warfarin and other oral anticoagulants (prolongs bleeding time). Increases nephrotoxicity of cyclosporine, increase the risk of CNS excitability and convulsive reactions against the background of NSAIDs. Medicines alkalinizing the urine (citrates, sodium bicarbonate, carbonic anhydrase inhibitors) reduce the solubility (increases the probability of crystalluria). Infusion solutions of ciprofloxacin ready to use can be combined with infusion solutions: 0.9% sodium chloride solution, Ringer's solution, Ringer lactate, 5 and 10% dextrose, 10% solution of fructose, and a solution containing 5% dextrose with 0,225 or 0.45% sodium chloride. Incompatible with solutions having a pH > 7.

Panthor side effects

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Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Rare

Fever

skin rash or itching

sore throat and fever

unusual tiredness and weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Abdominal or stomach pain or upset

diarrhea

nausea or vomiting

Rare

Dizziness

hair loss

headache

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Panthor contraindications

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Injection: Panthor is contraindicated in comatose states, in patients who have received large amounts of central-nervous-system depressants (alcohol, sedative hypnotics, including barbiturates, general anesthetics, narcotics, narcotic analgesics, tranquilizers, etc.), and in patients who have demonstrated an idiosyncrasy or hypersensitivity to promethazine.

Under no circumstances should promethazine be given by intra-arterial injection due to the likelihood of severe arteriospasm and the possibility of resultant gangrene

Panthor HCl injection should not be given by the subcutaneous route; evidence of chemical irritation has been noted, and necrotic lesions have resulted on rare occasions following subcutaneous injection. The preferred parenteral route of administration is by deep intramuscular injection.

Syrup, Tablets and Suppositories: Phenergan Tablets and Suppositories are contraindicated for use in pediatric patients less than two years of age.

Phenergan Tablets and Suppositories are contraindicated in comatose states, and in individuals known to be hypersensitive or to have had an idiosyncratic reaction to promethazine or to other phenothiazines.

Antihistamines are contraindicated for use in the treatment of lower respiratory tract symptoms including asthma.



Active ingredient matches for Panthor:

Chlorphenamine in India.

Ammonium Chloride/Chlorpheniramine/Sodium Citrate

Ammonium chloride/chlorpheniramine maleate/sodium citrate in India.


Unit description / dosage (Manufacturer)Price, USD
Panthor Na Citrate 50mg, Chlorphenamine Maleate 2mg, Ammon Cl 100mg/5mL LIQD / 100ml$ 0.32
100ml$ 0.32
PANTHOR 2MG/100MG/50MG SYRUP 1 bottle / 100 ML syrup each (Juggat Pharma)$ 0.66
PANTHOR 2MG/100MG/50MG SYRUP 1 bottle / 125 ML syrup each (Juggat Pharma)$ 0.64
PANTHOR 2MG/100MG/50MG SYRUP 1 bottle / 450 ML syrup each (Juggat Pharma)$ 0.66
PANTHOR oral liqd 100ml (Juggat)$ 0.66
Panthor Syrup (Juggat Pharma)$ 0.72

List of Panthor substitutes (brand and generic names):

Pabicon 5 mg/1 mL x 1's
Patarphen 2 mg/5 mL x 60 mL x 12's
Patarphen 2 mg/5 mL x 60 mL x 50's
Patarphen 2 mg/5 mL x 3, 800 mL
Pehachlor 4 mg x 1500's (Phapros)$ 13.19
Phenamin 5 mg/1 mL x 1 mL (Intas)
Phenamin 5mg x 5mL SYR / 60ml (Intas)$ 0.31
PHENAMIN 25MG INJECTION 1 vial / 2 ML injection each (Intas)$ 0.05
PHENAMIN 5MG SYRUP 1 bottle / 60 ML syrup each (Intas)$ 0.10
PHENAMIN syr 5 mg x 5 mL x 60ml (Intas)$ 0.31
Phenamin 25mg Injection (Intas)$ 0.02
Phenamin 5mg Syrup (Intas)$ 0.10
Phil Pharmawealth/Atlantic Chlorphenamine / amp 10 mg/1 mL x 1 mL x 50's (Atlantic Lab)
Phil Pharmawealth/Atlantic Chlorphenamine inj 10 mg/mL / amp 1 mL x 50 x 1's (Atlantic Lab)
Pirimat 10 mg/1 mL x 100's (CCM Duopharma BioTech)
Pirimat 10 mg/1 mL x 10 mL x 25's (CCM Duopharma BioTech)
Pirimat 10 mg/1 mL x 1's (CCM Duopharma BioTech)
Pirimat inj / amp 10 mg/mL 10 x 1's (CCM Duopharma BioTech)
Pirimat inj / vial 10 mg/mL 10 mL x 25 x 1's (CCM Duopharma BioTech)
Syrup; Oral; Chlorpheniramine Maleate 2 mg / 5 ml (GSK)
Tablet; Oral; Chlorpheniramine Maleate 4 mg (GSK)
Piriton 4 mg x 60's (GSK)
Piriton 4mg TAB / 500 (GSK)$ 0.35
Piriton 4 mg x 6's (GSK)
Piriton 4 mg x 30's (GSK)
4 mg x 500's (GSK)$ 0.35
PIRITON 2.5 MG/125 MG/55 MG EXPECTORANT 1 bottle / 100 ML expectorant each (GSK)$ 0.77
PIRITON 4 MG/125 MG/55 MG EXPECTORANT 1 bottle / 450 ML expectorant each (GSK)$ 0.94
PIRITON 4 MG/125 MG/55 MG EXPECTORANT 1 bottle / 115 ML expectorant each (GSK)$ 0.71
PIRITON 4 MG TABLET 1 packet / 500 tablets each (GSK)$ 0.62
PIRITON SYRUP 1 bottle / 120 ML syrup each (GSK)$ 0.71

References

  1. DailyMed. "CHLORPHENIRAMINE POLISTIREX; HYDROCODONE POLISTIREX: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "SODIUM CITRATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. DailyMed. "AMMONIUM CHLORIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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