Pd-LYTE-G Uses

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Pd-LYTE-G indications

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Pd-LYTE-G Injection, USP, after dilution in isotonic sodium chloride injection, may be indicated in the treatment of patients with (1) hypochloremic states and (2) metabolic alkalosis.

Uses of Pd-LYTE-G in details

Pd-LYTE-G is used for the relief of cough in the form of cough expectorant. It is also used as an injection to treat patients with hypochloremia and metabolic alkalosis.

Pd-LYTE-G dosage

Pd-LYTE-G Injection, USP is administered intravenously and must be diluted before use. Solutions for intravenous infusion should not exceed a concentration of 1% to 2% of Pd-LYTE-G.

Dosage is dependent upon the condition and tolerance of the patient. It is recommended that the contents of one to two vials (100 to 200 mEq) be added to 500 or 1000 mL of isotonic (0.9%) sodium chloride injection. The rate of intravenous infusion should not exceed 5 mL per minute in adults (approximately 3 hours for infusion of 1000 mL). Dosage should be monitored by repeated serum bicarbonate determinations.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. See PRECAUTIONS.

Pd-LYTE-G interactions

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In a treatment, patients should be monitored closely for signs of ammonia poisoning: pallor, sweating, irregular breathing, vomiting, bradycardia, arrhythmias, tremors, convulsions and coma.

Pd-LYTE-G should be used with caution in patients with heart and lung failure.

A longer-term correction of a hypochloraemia in patients with secondary metabolic alkalosis due to an intracellular potassium depletion can not be achieved by the sole administration of Pd-LYTE-G. Concomitant administration of potassium is also necessary.

Pd-LYTE-G side effects

See also:
What are the possible side effects of Pd-LYTE-G?

Rapid intravenous administration of Pd-LYTE-G may be accompanied by pain or irritation at the site of injection or along the venous route.

Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia (from large volume diluent).

If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary.

Pd-LYTE-G contraindications

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Pd-LYTE-G is contraindicated in patients with severe impairment of renal or hepatic function.

Pd-LYTE-G should not be administered when metabolic alkalosis due to vomiting of hydrochloric acid is accompanied by loss of sodium (excretion of sodium bicarbonate in the urine).

Active ingredient matches for Pd-LYTE-G:

Ammonium chloride in India.

Anhydrous dextrose/potassium chloride/sodium chloride/sodium sulphite in India.


Unit description / dosage (Manufacturer)Price, USD
500ml$ 0.40
PD-LYTE-G infusion 500ml (Parenteral Drugs)$ 0.40

List of Pd-LYTE-G substitutes (brand and generic names):

Oricof 100 ml Syrup (Orison Pharmaceuticals)$ 0.02
Oril Expectorant 110 ml Expectorant (Optho Remedies Pvt.Ltd.)$ 0.01
Osodryl 100 ml Syrup (Osho Pharma Pvt.Ltd.)$ 0.02
Oyiskof G 100 ml Syrup (Oyster Labs Limited)$ 0.02
Quino Plasmol Strong Syrup (Universal Drug House Pvt Ltd)$ 0.03
Sardryl 100 ml Syrup (Saar Biotech)$ 0.02
Sardryl 60 ml Syrup (Saar Biotech)$ 0.03
Scordryl 100 ml Syrup (Scortis Labs (P) Ltd)$ 0.02
Silvina DB 100 ml Syrup (Silicon Pharma (Rhombus Pharma Pvt Ltd))$ 0.06
Siokof P 60 ml Syrup (Albert David Limited)$ 0.02
Siokof P Syrup (Albert David Limited)$ 0.28
Soventol Exp. 100 ml Expectorant (Nicholas Piramal India Ltd.)$ 0.02
Sputes Expectorant 100 ml Expectorant (Agron Remedies Pvt Ltd)$ 0.02
Sudex Exp 100 ml Expectorant (Comed Chemicals Pvt Ltd)$ 0.01
Sudex Exp 100 ml Eastern Drugs Expectorant (Comed Chemicals Pvt Ltd)$ 0.02
Sudex Exp 50 ml Expectorant (Comed Chemicals Pvt Ltd)$ 0.01
SUDEX EXP syr 100ml (Comed Chemicals Pvt Ltd)$ 0.20
SUDEX EXP syr 50ml (Comed Chemicals Pvt Ltd)$ 0.13
Syncof 100 ml Syrup (Smilax Pharmaceuticals)$ 0.02
Syncof 50 ml Syrup (Smilax Pharmaceuticals)$ 0.02
Tri Cough 100 ml Syrup (Maitri Healthcare Pvt. Ltd.)$ 0.00
Tricos 100 ml Syrup (Atlantic Pharmaceuticals)$ 0.03
Tripex 100 ml Syrup (Modgal Pharmaceuticals (P) Ltd.)$ 0.03
Trodryl 100 ml Syrup (Divine Pharma)$ 0.03
Tussoric Cough 100 ml Syrup (Euphoric Pharmaceuticals Pvt.Ltd.)$ 0.02
Vencof SF 100 ml Syrup (Intra Labs India Pvt Ltd)$ 0.02
Viscodril Lite 100 ml Expectorant (Invision Medi Sciences)$ 0.03
Vividryl 100 ml Syrup (Vivid Biotek Pvt. Ltd.)$ 0.03
Windryl 100 ml Syrup (Mediwin Pharmaceuticals)$ 0.01
Zecof 100 ml Syrup (Winmac Laboratories Limited)$ 0.02
Zotakof C 100 ml Syrup (Zota Pharmaceuticals (Zota Healthcare Pvt Ltd))$ 0.02

References

  1. DailyMed. "AMINO ACIDS; CALCIUM ACETATE; GLYCERIN; MAGNESIUM ACETATE; PHOSPHORIC ACID; POTASSIUM CHLORIDE; SODIUM ACETATE; SODIUM CHLORIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "AMMONIUM CHLORIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. PubChem. "Potassium". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

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Information checked by Dr. Sachin Kumar, MD Pharmacology

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