Polysilane Uses

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Polysilane indications

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Topical/Cutaneous

Head pediculosis

Adult: A 4% solution is used for treatment.

Child: >6 mth: A 4% solution is used for treatment.

Topical/Cutaneous

As a skin protectant

Adult: As cream containing Polysilane 22% w/w and benzalkonium chloride 0.1% w/w. Apply to the affected area several times a day as needed.

Polysilane description

Polysilane contains Dimeticone (silicone) 15%, cetyl alcohol (hexadecanol) 5% and glycerol 2%, in a lanolin-free cream base. It also contains methylhydroxybenzoate 0.2% and propylhydroxybenzoate 0.1% as preservatives. It has a pH of 6.

Polysilane does not contain perfume, lanolin or lanolin derivatives.

Polysilane dosage

Adults: Improvement of Abdominal Symptoms Due to Gas in the Gastrointestinal Tract: 120-240 mg daily divided into 3 times after or between meals by oral route.

Elimination of Foamy Mucus in the Stomach Prior to Gastric Endoscopy: 40-80 mg with about 10 mL of water at 15-40 min prior to the test by oral route.

Elimination of Gas in the Intestine Prior to Abdominal X-Ray Examination: 120-240 mg daily divided into 3 times after or between meals for 3-4 days prior to the test by oral route.

Some adjustments may be made according to the age and symptom of the patient.

Administration: Polysilane Drops: Shake and then use.

Polysilane interactions

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Do not take this product if you are presently taking a prescription antibiotic drug of any form of tetracycline.

The rate and/or extent of absorption of many drugs may be increased or decreased when they are used concurrently with antacids.

Therefore, as a general rule, medication should not be taken within one to two hours of an antacid, if possible.

An incomplete list of substances for which the above statement has been shown to apply includes: tetracycline, iron sans, chlorpromazine, levodopa, isoniazid, digoxin, H2-antagonists, indomethacin, nitrofurantin, and dicumard.

An increase in the plasma level of quinidine and possible toxicity may result if alkalization of the urine occurs during antacid therapy.

Polysilane side effects

Adverse reactions were reported in 16 of 2546 patients (0.63%) treated with Polysilane. The most frequently observed adverse reactions were soft stools in 8 patients (0.31%), gastric discomfort in 4 patients (0.16%), diarrhea in 3 patients (0.12%) and stomachache in 3 patients (0.12%). No abnormal changes were reported in laboratory tests. (At the end of the re-evaluation.) See Table 2.

Polysilane contraindications

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Tuberculous, viral lesions of the skin (e.g. herpes simplex and varicella); fungal lesions not susceptible to nystatin, facial rosacea, acne vulgaris or perioral dermatitis. Not to be applied to the external auditory canal in patients with perforated tympanic membranes. Do not use on extensive areas to reduce risk of systemic absorption and neomycin-induced ototoxicity. Not recommended for <1 yr.

Active ingredient matches for Polysilane:

Dimeticone in Oman.

Al3/aluminium hydroxide/carob flour/dimethicone/Magnesium hydroxide/Mg2 in Indonesia.

Al3/dimethicone in Thailand.

Al3/simethicone in Malaysia.

Aluminium Hydroxide/Simethicone

Aluminium hydroxide/dimethicone in Hong Kong, Thailand, Singapore, Malaysia.

Dimethicone in Netherlands.


Unit description / dosage (Manufacturer)Price, USD
Gel; Oral; Aluminum Hydroxide; Simethicone
Polysilane 5 x 8's$ 3.48
Polysilane 100 mL x 1's$ 2.11
Polysilane 180 mL x 1's$ 3.48
Polysilane / cap 60's$ 4.50

List of Polysilane substitutes (brand and generic names):

Gel; Oral; Dimethicone 2.25 g
Wipe; Topical; Dimethicone 3.2%
Wipe; Topical; Dimethicone 3.2%
Rosken Skin Repair Cream 15 mL x 1's
Rosken Skin Repair Cream 75 mL x 1's
Rosken Skin Repair Cream 200 mL x 1's
Rosken Skin Repair Cream 250 mL x 1's
Rosken Skin Repair Cream 375 mL x 1's
Sheclin Gold Skin 40 gm Cream (HRD Supra Healthcare)$ 2.65
Silent SF Skin 50 gm Cream (American Remedies Limited.)$ 0.45
Suspension; Oral; Dimethicone
Silic 15 75 g (Ego)
Silic 15 75 g x 1's (Ego)
Silic 15 500 g x 1's (Ego)
Silic 15 200 g x 1's (Ego)
Silic 15 500 g (Ego)
Silic 15 cream 75 g x 1's (Ego)
Silic 15 cream 500 g x 1's (Ego)

References

  1. DailyMed. "MAGNESIUM HYDROXIDE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. PubChem. "DIMETHICONE". https://pubchem.ncbi.nlm.nih.gov/sub... (accessed September 17, 2018).
  3. PubChem. "Carob". https://pubchem.ncbi.nlm.nih.gov/sub... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Polysilane are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Polysilane. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


Consumer reported price estimates

No survey data has been collected yet


1 consumer reported time for results

To what extent do I have to use Polysilane before I begin to see changes in my health conditions?
As part of the reports released by ndrugs.com website users, it takes 1 day and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Polysilane. To get the time effectiveness of using Polysilane drug by other patients, please click here.
Users%
1 day1
100.0%


8 consumers reported age

Users%
16-293
37.5%
< 12
25.0%
6-151
12.5%
1-51
12.5%
30-451
12.5%


Consumer reviews


There are no reviews yet. Be the first to write one!


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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