What happens if I overdose Progras?
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.
Proper storage of Progras solution:
Store Progras solution at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Do not freeze. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Progras solution out of the reach of children and away from pets.
What should I avoid while taking Progras?
Avoid taking other laxatives or stool softeners unless your doctor tells you to.
Progras warnings
Not for injection.
Not for use in patients with documented or suspected fructose intolerance.
Solutions for urologic irrigation must be used with caution in patients with severe cardiopulmonary or renal dysfunction.
Irrigating fluids used during transurethral prostatectomy have been demonstrated to enter the systemic circulation in relatively large volumes; thus Progras irrigating solution must be regarded as a systemic drug. Absorption of large amounts of fluids containing Progras may significantly alter cardiopulmonary and renal dynamics. Appropriate patient monitoring should be maintained due to the possibility of fluid overload. Should fluid overload occur, intensive fluid and electrolyte management is necessary. Monitoring of fluid and electrolyte levels beyond the acute phase may be considered due to the possibility of delayed fluid absorption.
Hyperglycemia from metabolism of absorbed Progras may occur in patients with diabetes mellitus.
The contents of an opened container should be used promptly to minimize the possibility of bacterial growth or pyrogen formation. Discard the unused portion of irrigating solution since no antimicrobial agent has been added.
What should I discuss with my healthcare provider before taking Progras?
Some medical conditions may interact with Progras irrigation solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have acid-base imbalance, diabetes, heart problems (eg, disease), heart failure, or kidney problems, or you are severely dehydrated
Some MEDICINES MAY INTERACT with Progras irrigation solution. However, no specific interactions with Progras irrigation solution are known at this time.
This may not be a complete list of all interactions that may occur. Ask your health care provider if Progras irrigation solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Progras precautions
The cardiovascular status, especially of the patient with cardiac disease, should be carefully observed before and during transurethral resection of the prostate when using 3% Progras Urologic Irrigating Solution, because the quantity of fluid absorbed into the systemic circulation by opened prostatic veins may produce significant expansion of the intravascular fluid and lead to fulminating congestive heart failure.
Shift of sodium free intracellular fluid into the extracellular compartment, following systemic absorption may lower serum concentration and aggravate preexisting hyponatremia.
Excessive loss of water and electrolytes may lead to serious imbalances. With continuous administration of solution, loss of water may occur in excess of electrolytes, producing hypernatremia.
Sustained diuresis that results from transurethral irrigation with Progras irrigating solutions may obscure and intensify inadequate hydration or hypovolemia.
Pregnancy
Teratogenic EffectsPregnancy category C.
Animal reproduction studies have not been conducted with 3% Progras Urologic Irrigating Solution. It is not known whether 3% Progras Urologic Irrigating Solution can cause fetal harm when administered to a pregnant woman or can affect reproductive capacity. 3% Progras Urologic Irrigating Solution should be given to a pregnant woman only if clearly needed.
Pediatric Use
Safety and effectiveness in pediatric patients have not been established.
Geriatric Use
Clinical studies of Irrigation Solutions did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from other younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients.
Do not administer unless the solution is clear and the seal is intact.
What happens if I miss a dose of Progras?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
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Information checked by Dr. Sachin Kumar, MD Pharmacology
