Consists of bromhexine hydrochloride, guaiphenesin, terbutaline sulphate
Bromhexine hydrochloride (Rexcore-SF) indications
respiratory-tract disorders with viscous mucus
Uses of Bromhexine hydrochloride (Rexcore-SF) in details
Bromhexine hydrochloride (Rexcore-SF) is used to treat breathing difficulties caused by excessive mucus secretions in the air passages associated with respiratory tract infections.
Bromhexine hydrochloride (Rexcore-SF) description
Bromhexine hydrochloride (Rexcore-SF) is an expectorant/mucolytic agent. Bromhexine hydrochloride (Rexcore-SF) is in the United States. It is marketed under the trade name Bromhexine hydrochloride (Rexcore-SF)(R) in Germany, England, Belgium, France, Italy, Netherlands, Norway, Sweden, Australia, and South Africa.
Bromhexine hydrochloride (Rexcore-SF) dosage
Unless otherwise prescribed, the following doses are recommended:
Tablet: Adults and Children >12 years: 8 mg (1 tab) thrice daily; 6-12 years: 4 mg (½ tab) thrice daily; 2-6 years: 4 mg (½ tab) twice daily.
Oral Solution:
Adults and Children >12 years: 4 mL thrice daily; 6-12 years: 2 mL thrice daily; 2-6 years: 20 drops thrice daily; <2 years: 10 drops thrice daily.Inhalation Solution (with aerosol apparatus): It is generally recommended to warm inhalation solution to body temperature before inhalation. Patients with bronchial asthma may be advised to commencing inhalation after they have taken their regular bronchospasmolytic therapy.
Adults: 4 mL. Children >12 years: 2 mL; 6-12 years: 1 mL; 2-6 years: 10 drops; <2 years: 5 drops. All doses to be taken twice daily.
The solution may be diluted 1:1 in physiological saline solution. In order to avoid precipitation, the solution should be inhaled immediately after mixing. The combined administration of inhalation and oral application intensifies the effect, and is especially suited for the commencement of treatment in cases where the full effect is to be reached quickly.
Syrup: Adults and Children >12 years: 5 ml (1 tsp) thrice daily.
At commencement of treatment, it may be necessary to increase the total daily dose up to 48 mg in adults.
The syrup is sugar-free and therefore suitable for diabetics and small children.
Ampoule: Severe cases, before and after surgical intervention: 1 amp SC, IM or IV (duration of injection: 2-3 min) 2-3 times daily.
Capsule: Adults: 1 cap 3 times daily.
It is recommended for the initial phase of treatment usually lasting not more than a week.
Patients being treated with Bromhexine hydrochloride (Rexcore-SF) should be notified of an expected increase in the flow of secretions.
Bromhexine hydrochloride (Rexcore-SF) interactions
A reduction in dose of cardiac glycosides (e.g. digitalis) and quinidine might become necessary in patients suffering from congestive cardiac failure because of the positive inotropic effect of orciprenaline sulphate.
Bromhexine hydrochloride (Rexcore-SF) hydrochloride SYRUP should not be administered concomitantly with beta-blocking agents, due to orciprenaline’s reversal of anti-hypertensive action.
The concomitant use of other sympathomimetic agents should be carefully controlled to avoid potentiation of effects.
Bromhexine hydrochloride (Rexcore-SF) side effects
Like all medicines, Bromhexine hydrochloride (Rexcore-SF) can have side effects. Bromhexine hydrochloride (Rexcore-SF) is, in general, easily digested, both in the short
and the long-term.
Very exceptionally: queasiness, a heavy feeling in the stomach.
If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your
doctor or pharmacist.
Bromhexine hydrochloride (Rexcore-SF) contraindications
Bromhexine hydrochloride (Rexcore-SF) hydrochloride SYRUP is contra-indicated in patients with known hypersensitivity to sympathomimetic amines or any of the other ingredients; hypertrophic obstructive cardiomyopathy; and tachyarrhythmia.
Sympathomimetics, such as orciprenaline sulphate, may interact with monoamine oxidase inhibitors (MAOI), and therefore Bromhexine hydrochloride (Rexcore-SF) hydrochloride SYRUP should not be given to patients receiving such treatment or within 14 days of MAOI treatment termination.
Safety in pregnancy and lactation has not been established.
Guaiphenesin (Rexcore-SF) indications
Helps loosen phlegm & helps clear chest congestion.
Guaiphenesin (Rexcore-SF) description
A centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1206)
Guaiphenesin (Rexcore-SF) dosage
Adult & childn >12 yr 10-20 mL. Childn 6-12 yr 5-10 mL. To be taken 4 hrly. Max: 6 doses/24 hr.
Guaiphenesin (Rexcore-SF) interactions
No information available.
Guaiphenesin (Rexcore-SF) side effects
Diarrhea, laxative effect.
Guaiphenesin (Rexcore-SF) contraindications
Guaiphenesin (Rexcore-SF) Tablets are contraindicated in patients hypersensitive to any of the ingredients.
What is Terbutaline sulphate (Rexcore-SF)?
Terbutaline sulphate (Rexcore-SF) is a bronchodilator that is used to treat or prevent bronchospasm (wheezing, chest tightness, trouble breathing) in people with lung conditions such as asthma, bronchitis, or emphysema.
Terbutaline sulphate (Rexcore-SF) is for use in adults and children at least 12 years old.
Terbutaline sulphate (Rexcore-SF) may also be used for purposes not listed in this medication guide.
Terbutaline sulphate (Rexcore-SF) indications
Acute & chronic bronchitis, bronchiectasis, bronchial asthma, whooping cough, emphysema, atelectasis, pulmonary TB, pneumonia & other broncho-spastic conditions.
How should I use Terbutaline sulphate (Rexcore-SF)?
Use Terbutaline sulphate (Rexcore-SF) as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Terbutaline sulphate (Rexcore-SF) is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Terbutaline sulphate (Rexcore-SF) at home, a health care provider will teach you how to use it. Be sure you understand how to use Terbutaline sulphate (Rexcore-SF). Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
- Do not use Terbutaline sulphate (Rexcore-SF) if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
- Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
- If you miss a dose of Terbutaline sulphate (Rexcore-SF) and are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Terbutaline sulphate (Rexcore-SF).
Terbutaline sulphate (Rexcore-SF) description
Terbutaline sulphate (Rexcore-SF) turbuhaler is a breath-activated, multiple-dose powder inhaler free from propellant, lubricant, preservative, carrier substances or other additives.
Terbutaline sulphate (Rexcore-SF) injection also contains the following inactive ingredients: Sodium chloride, HCl (for pH adjustment) and water for injections.
Terbutaline sulphate is 2-(tert-butylamino)-1-(3,5-dihydroxyphenyl)ethanol sulphate.
Terbutaline sulphate (Rexcore-SF) dosage
Adult: 10 ml, tid. Child <6 yrs: 5 ml; 6-12 yrs: 5 ml-10 ml, tid.
Terbutaline sulphate (Rexcore-SF) interactions
See also:
What other drugs will affect Terbutaline sulphate (Rexcore-SF)?
Drug Interactions
The concomitant use of Terbutaline sulphate (Rexcore-SF) with other sympathomimetic agents is not recommended, since the combined effect on the cardiovascular system may be deleterious to the patient
Monoamine Oxidase Inhibitors or Tricyclic Antidepressants: Terbutaline sulphate (Rexcore-SF) should be administered with extreme caution to patients being treated with monoamine oxidase inhibitors or tricyclic antidepressants, or within 2 weeks of discontinuation of such agents, since the action of terbutaline on the vascular system may be potentiated
Beta-Blockers Beta-adrenergic receptor blocking agents not only block the pulmonary effect of beta-agonists, such as Terbutaline sulphate (Rexcore-SF), but may produce severe bronchospasm in asthmatic patients. Therefore, patients with asthma should not normally be treated with beta-blockers. However, under certain circumstances, e.g., as prophylaxis after myocardial infarction, there may be no acceptable alternatives to the use of beta-adrenergic blocking agents in patients with asthma. In this setting, cardioselective beta-blockers could be considered, although they should be administered with caution
Diuretics The ECG changes and/or hypokalemia that may result from the administration of nonpotassium-sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. Although the clinical significance of these effects is not known, caution is advised in the coadministration of beta-agonists with nonpotassium-sparing diuretics.
Terbutaline sulphate (Rexcore-SF) side effects
See also:
What are the possible side effects of Terbutaline sulphate (Rexcore-SF)?
Applies to terbutaline: oral elixir, oral tablet
Other dosage forms:
- subcutaneous solution
In addition to its needed effects, some unwanted effects may be caused by terbutaline (the active ingredient contained in Terbutaline sulphate (Rexcore-SF)). In the event that any of these side effects do occur, they may require medical attention.
Major Side Effects
You should check with your doctor immediately if any of these side effects occur when taking terbutaline:
More common:
- Shakiness in the legs, arms, hands, or feet
- trembling or shaking of the hands or feet
- Extra heartbeat
- feeling faint, dizzy, or lightheadedness
- feeling of warmth or heat
- flushing or redness of the skin, especially on the face and neck
- headache
- sweating
- Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- excessive muscle tone
- muscle stiffness
- muscle tension or tightness
If any of the following symptoms of overdose occur while taking terbutaline, get emergency help immediately:
Symptoms of overdose:
- Arm, back, or jaw pain
- blurred vision
- chest pain or discomfort
- chest tightness or heaviness
- confusion
- convulsions
- decreased urine
- dizziness
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- dry mouth
- fainting
- fast, pounding, or irregular heartbeat or pulse
- general feeling of discomfort or illness
- increased thirst
- loss of appetite
- mood changes
- muscle pain or cramps
- nausea or vomiting
- nervousness
- numbness or tingling in the hands, feet, or lips
- pounding in the ears
- seizures
- shortness of breath
- sleeplessness
- slow or fast heartbeat
- trouble sleeping
- unable to sleep
- unusual tiredness or weakness
Minor Side Effects
Some of the side effects that can occur with terbutaline may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
More common:
- Sleepiness or unusual drowsiness
- Anxiety
- lack or loss of strength
- Fever
- rash
- redness, soreness, or itching skin
- seeing, hearing, or feeling things that are not there
- sores, welting, or blisters
Terbutaline sulphate (Rexcore-SF) contraindications
See also:
What is the most important information I should know about Terbutaline sulphate (Rexcore-SF)?
Hypersensitivity to sympathomimetic amines or to any of the ingredients of Terbutaline sulphate (Rexcore-SF). Prolonged tocolysis.
Active ingredient matches for Rexcore-SF:
Bromhexine hydrochloride/guaiphenesin/terbutaline sulphate in India.
| Unit description / dosage (Manufacturer) | Price, USD |
| REXCORE-SF syr 100ml (Lividus) | $ 0.78 |
List of Rexcore-SF substitutes (brand and generic names): | |
| B-KOF EXP (India) | |
| B-KOF EXP syr 100ml (Bewell) | $ 0.34 |
| BESILENT (India) | |
| BESILENT syr 30ml (Shirr) | $ 0.66 |
| BIOVENT-A EXP (India) | |
| BIOVENT-A EXP syr 100ml (Bioxis) | $ 0.65 |
| BRO-ZEDEX-SF EXP (India) | |
| BRO-ZEDEX-SF EXP syr 100ml (Wockhardt) | $ 0.69 |
| bromhexine hydrochloride/guaiphenesin/terbutaline sulphate (India) | |
| ELEDYL EXP (India) | |
| ELEDYL EXP syr 100ml (Mandar) | $ 0.34 |
| NISIBRO (India) | |
| NISIBRO syr 100ml (Neiss) | $ 0.80 |
| ORIPECT TAB (India) | |
| ORIPECT TAB tab 10's (Stanford) | $ 0.18 |
| ORIPECT-SF (India) | |
| ORIPECT-SF syr 100ml (Stanford) | $ 0.60 |
| PULMO-REST JUNIOR EXP (India) | |
| PULMO-REST JUNIOR EXP syr 100ml (Stadmed) | $ 0.41 |
References
- DailyMed. "TERBUTALINE SULFATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "terbutaline". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- PubChem. "bromhexine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Rexcore-SF are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Rexcore-SF. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yet1 consumer reported price estimates
Was the price you paid to purchase the drug reasonable? Did you feel it was expensive?The below mentioned numbers have been reported by ndrugs.com website users about whether the Rexcore-SF drug is expensive or inexpensive. There is a mixed opinion among users. The rating about the cost of the drug depends on factors like which brand drug the patient purchased, how effective it was for the price paid, the country or place the drug is marketed, and the economic condition of the patient. The users who feel the drug is expensive can look for an alternative brand drug or a generic drug to save the cost.
| Users | % | ||
|---|---|---|---|
| Not expensive | 1 | 100.0% | |
1 consumer reported time for results
To what extent do I have to use Rexcore-SF before I begin to see changes in my health conditions?As part of the reports released by ndrugs.com website users, it takes 1 day and a few days before you notice an improvement in your health conditions.
Please note, it doesn't mean you will start to notice such health improvement in the same time frame as other users. There are many factors to consider, and we implore you to visit your doctor to know how long before you can see improvements in your health while taking Rexcore-SF. To get the time effectiveness of using Rexcore-SF drug by other patients, please click here.
| Users | % | ||
|---|---|---|---|
| 1 day | 1 | 100.0% | |
8 consumers reported age
| Users | % | ||
|---|---|---|---|
| > 60 | 2 | 25.0% | |
| < 1 | 2 | 25.0% | |
| 46-60 | 1 | 12.5% | |
| 6-15 | 1 | 12.5% | |
| 30-45 | 1 | 12.5% | |
| 1-5 | 1 | 12.5% | |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
