What is Rino-Clenil?
Rino-Clenil is a steroid. It prevents the release of substances in the body that cause inflammation.
Rino-Clenil nasal is used to treat nasal symptoms such as congestion, sneezing, and runny nose caused by seasonal or year-round allergies. The Rino-Clenil brand of this medication is also used to keep nasal polyps from coming back after surgery to remove them.
Rino-Clenil may also be used for purposes not listed in this medication guide.
Rino-Clenil indications
Maintenance treatment of asthma as prophylactic therapy in adults and children (≥5 years). For asthma patients who require systemic corticosteroid administration where adding Rino-Clenil dipropionate may reduce or eliminate the need for the systemic corticosteroids.
Rino-Clenil dipropionate is not indicated for the relief of acute bronchospasm.
Uses of Rino-Clenil in details
Rino-Clenil is used to treat runny nose, swelling and itching of the nose due to allergy (allergic rhinitis), hay fever and ulcerative colitis. Rino-Clenil reduces inflammation, swelling and irritation in nose and helps to relieve itching, sneezing and blocked or runny nose. It is also used in asthma and ulcerative colitis.
Rino-Clenil description
The dose which the patient gets through the mouthpiece of the device is 180 mcg.
Rino-Clenil contains 200 doses of finely powdered Rino-Clenil mixed in a small quantity of lactose. The amount of drug received by the patient (180 mcg/dose) corresponds to that from 2 puffs of the freon-based Rino-Clenil inhalation aerosol with a metered dose of 100 mcg/dose. The dose to be inhaled is released from the container by pressing the device between the thumb and the forefinger. This is followed by inhalation through the device. As a result, Rino-Clenil particles are transferred to their target, the lungs. Use of the Rino-Clenil does not require coordination of actuation of the dose and inhalation.
Rino-Clenil dosage
Management of Chronic Asthma: Adults and Children >12 years: 100-400 mcg twice daily. Maximum: 1000 mcg twice daily.
Children (5-12 years): 100-200 mcg twice daily. Maximum: 200-400 mcg twice daily.
Prophylaxis of Asthma: Adults and Children >12 years: 50-200 mcg twice daily. Increase if necessary to maximum 400 mcg twice daily.
Children (5-12 years): The usual starting dose is 100 mcg twice daily. Depending on the severity of asthma, the daily dose may be increased up to 400 mcg administered in 2-4 divided doses.
When patient's symptoms remain under satisfactory control, the dose should be titrated to the lowest dose at which effective control of asthma is maintained.
Therapy in New Patients: Mild Asthma: 50-100 mcg twice daily.
Moderate Asthma: 100-200 mcg twice daily.
Severe Asthma: 200-400 mcg twice daily.
When switching a patient with well-controlled asthma from another corticosteroid inhaler, initially Rino-Clenil 100 mcg puff should be prescribed for Rino-Clenil dipropionate (CFC) or budesonide 200-250 mcg; fluticasone propionate 100 mcg.
When switching a patient with poorly-controlled asthma from another corticosteroid inhaler, initially Rino-Clenil 100 mcg puff should be prescribed for Rino-Clenil dipropionate (CFC) or budesonide or fluticasone propionate 100 mcg. The dose of Rino-Clenil should be adjusted to response.
Use in the elderly or patients with hepatic or renal impairment: There are no special dosage recommendations for use in the elderly or in patients with hepatic or renal impairment.
Rino-Clenil interactions
See also:
What other drugs will affect Rino-Clenil?
Due to the very low plasma concentration achieved after inhaled dosing, clinically significant drug interactions are in general unlikely. Care should be taken when co-administering with known strong CYP3A4 inhibitors (eg, ketoconazole, itraconazole, nelfinavir, ritonavir) as there is a potential for increased systemic exposure to Rino-Clenil.
Rino-Clenil side effects
See also:
What are the possible side effects of Rino-Clenil?
The most commonly noted side effects associated with inhaled Rino-Clenil are mild cough or wheezing due to chemical irritation; these effects may be minimized by using an inhaled bronchodilator (e.g., albuterol or Ventolin) prior to the Rino-Clenil.
Oral candidiasis or thrush, a fungal infection of the mouth and throat, can occur in between 1 in 20 and 1 in 8 persons who use Rino-Clenil. The risk of thrush is greater with higher doses, but the risk in children is lower than in adults. Hoarseness may occur in as few as 1 in 20 or as many as 1 in 2 persons and is due to chemical irritation. A spacer device that can be attached to the inhaler and washing out the mouth with water following each use of Rino-Clenil reduces the amount of Rino-Clenil in the mouth and throat and reduces the risk of thrush and hoarseness.
Higher doses of inhaled Rino-Clenil (more than 1000 mcg/day) may result in more absorption into the body. This may decrease bone formation and increase bone breakdown (resorption), resulting in weak bones and a risk of fractures. Even higher doses (more than 1500 mcg/day in adults and 400 mcg/day in children) may suppress the adrenal glands and impair their ability to make natural glucocorticoid. People with such suppression (which can be identified by testing) need increased amounts of glucocorticoid orally or by the intravenous route during periods of high physical stress since higher amounts of glucocorticoids are needed by the body to fight physical stress. Patients receiving Rino-Clenil may develop easy bruising if enough Rino-Clenil is absorbed into the body from the lungs.
Rino-Clenil contraindications
Hypersensitivity to Rino-Clenil diproprionate or to any of the excipients of Rino-Clenil.
Active ingredient matches for Rino-Clenil:
Beclometasone in Cyprus, Egypt, Jordan, Kuwait, Lebanon, Oman, Saudi Arabia, Sri Lanka, Syria.
List of Rino-Clenil substitutes (brand and generic names) | Sort by popularity |
| Unit description / dosage (Manufacturer) | Price, USD |
| Rino Clenil (Thailand) | |
| Rino Clenil nasal spray 100 mcg/puff 200 actuation x 1's (Chiesi) | |
| Rinobek (Turkey) | |
| Rinoclenil (France, Malta, Romania, Tunisia, Turkey, Venezuela) | |
| Rinosol (Argentina, Greece, Malta) | |
| Rivanase (Canada) | |
| Aerosol, Metered-Dose; Inhalation; Beclomethasone Dipropionate 50 mcg / dose (Riva) | |
| Rivanase AQ (Canada) | |
| Rivanase AQ. (Canada) | |
| Salcoat (Japan, Taiwan) | |
| Salcoat 50 mcg x 100's (Teijin) | |
| Sanasthmax (Germany) | |
| Solution; Inhalation; Beclomethasone Dipropionate (Chiesi) | |
| Sanasthmax 250 Mikrogramm (Germany) | |
| Sanasthmax 400 Mikrogramm (Germany) | |
| Sanasthmax Junior (Germany) | |
| Sanasthmax Junior 50 Mikrogramm (Germany) | |
| Sanasthmyl (Germany) | |
| Powder; Inhalation; Beclomethasone Dipropionate 200 mcg / dose (Gsk) | |
| Sanasthmyl Rotadisk (Germany) | |
| Powder; Inhalation; Beclomethasone Dipropionate 200 mcg / dose | |
| Sandoz Beclomethasone (South Africa) | |
| Sarbet N | |
| Sarbet N Skin 15 gm Cream (Vsaar Pharma) | $ 0.33 |
| Selsyd-BN (India) | |
| Selsyd-BN Clotrimazole 1 % w/w, beclomethasone dipropionate0.025 % w/w, neomycin 0.5 %w/w. CRM / 15g (Psycorem) | $ 0.66 |
| SELSYD-BN cream 15g (Psycorem) | $ 0.66 |
| Sertacide-B (India) | |
| Sertacide-B Sertaconazole 2 %, beclometasone 0.025 %. CRM / 10g (Cipla (Xterna)) | $ 1.08 |
| SERTACIDE-B cream 10g (Cipla (Xterna)) | $ 1.08 |
| Shelic Cream (India) | |
| Shelic Cream Beclometasone 0.025 %, Salicylic acid 3 %. CRM / 15g (Zee Lab) | $ 0.70 |
| 15g (Zee Lab) | $ 0.70 |
| SHELIC CREAM cream 15g (Zee Lab) | $ 0.70 |
| Siloderm Mixi (India) | |
| Siloderm Mixi Clotrimazole 1 % w/w, Beclometasone dipropionate0.025 % w/w, Gentamicinsulfate 1 % w/w. CRM / 10g (US Vitamins Limited) | $ 0.25 |
| 10g (US Vitamins Limited) | $ 0.25 |
| Siloderm Mixi Skin 10 gm Cream (US Vitamins Limited) | $ 0.49 |
| SILODERM MIXI CREAM 1 tube / 10 GM cream each (US Vitamins Limited) | $ 0.59 |
| SILODERM MIXI cream 10g (US Vitamins Limited) | $ 0.49 |
| Sinase (India) | |
| 200ml (Cruise) | |
| Sinase Diastase 50 mg, pepsin 10 mg. SYR / 200ml (Cruise) | |
| SINASE syr 200ml (Cruise) | |
| Sofudate-B (India) | |
| Sofudate-B Fusidic acid 20 mg, beclomethasone dipropionate0.25 mg/1 g. CRM / 10g (Alobiote) | |
| SOFUDATE-B cream 10g (Alobiote) | |
| Spir (France) | |
| Stecort NM | |
| Stecort NM Skin 15 gm Cream (Stancare (Ranbaxy Laboratories Ltd)) | $ 0.23 |
| Steradin-HFA (Bangladesh) | |
| Supirocin B Plus | |
| Supirocin B Plus Skin 30 gm Cream (Glenmark Pharmaceuticals Ltd.) | $ 6.27 |
| Supirocin B Plus Skin 10 gm Cream (Glenmark Pharmaceuticals Ltd.) | $ 2.53 |
| Supirocin B Plus Skin 20 gm Cream (Glenmark Pharmaceuticals Ltd.) | $ 3.73 |
| Supirocin B Plus Ointment (Glenmark Pharmaceuticals Ltd.) | $ 0.37 |
| Taunus (Japan) | |
See 1295 substitutes for Rino-Clenil | |
References
- DailyMed. "BECLOMETHASONE DIPROPIONATE MONOHYDRATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
- PubChem. "BECLOMETHASONE DIPROPIONATE". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).
- DrugBank. "BECLOMETHASONE DIPROPIONATE". http://www.drugbank.ca/drugs/DB00394 (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Rino-Clenil are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Rino-Clenil. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported useful
No survey data has been collected yetConsumer reported price estimates
No survey data has been collected yetConsumer reported time for results
No survey data has been collected yet3 consumers reported age
| Users | % | ||
|---|---|---|---|
| 6-15 | 2 | 66.7% | |
| 16-29 | 1 | 33.3% | |
Consumer reviews
There are no reviews yet. Be the first to write one! |
Information checked by Dr. Sachin Kumar, MD Pharmacology
