Rinostat Plus Uses

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What is Rinostat Plus?

Rinostat Plus is a decongestant. It works by constricting (shrinking) blood vessels (veins and arteries) in your body. Constriction of blood vessels in your sinuses, nose, and chest allows drainage of those areas, which decreases congestion.

Rinostat Plus is used to treat the congestion associated with allergies, hay fever, sinus irritation, and the common cold. Rinostat Plus also causes a decrease in appetite and is used in some over-the-counter diet aids.

Rinostat Plus has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain Rinostat Plus.

Rinostat Plus may also be used for purposes other than those listed in this medication guide.

Rinostat Plus indications

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Oral

Nasal congestion

Adult: Per cap contains a combination w/ Rinostat Plus HCl 18 mg: ≥13 yr 2 cap 4 hrly. Max: 8 cap/day. Per tab contains a combination w/ Rinostat Plus HCl 25 mg: ≥13 yr 1 tab 4 hrly. Max: 4 tab/day.

Child: Per cap contains a combination w/ Rinostat Plus HCl 18 mg: 6-12 yr 1 cap 4 hrly. Max: 4 cap/day. As oral liquid containing Rinostat Plus 2.5 mg/5 mL: 6 mth-2 yr 2.5 mL tid, 3-5 yr 5 mL 3-4 times daily, 6-12 yr 5-10 mL 3-4 times daily.

Uses of Rinostat Plus in details

Rinostat Plus is used to relieve blocked nose or sinuses caused by common cold and seasonal nasal allergies (hay fever). It is also used to decrease appetite for weight Rinostat Plus.

Rinostat Plus description

Rinostat Plus has been withdrawn in Canada and the United States. In November 2000, the Food and Drug Administration (FDA) issued a public health advisory against the use of the drug.

Rinostat Plus dosage

Rinostat Plus Dosage

Applies to the following strengths: 75 mg; 25 mg; 37.5 mg; 50 mg; 180 mg-75 mg

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Nasal Congestion

25 mg orally every 4 hours.

-or-

75 mg orally extended release every 12 hours.

Not to exceed 150 mg/day.

Usual Adult Dose for Weight Loss

25 mg orally 3 times a day, one-half hour before meals.

-or-

75 mg orally extended release once a day in the morning.

The use of Rinostat Plus for weight loss should be limited to 12 weeks.

Usual Pediatric Dose for Nasal Congestion

2 to 6 years:

6.25 mg orally every 4 hours. Maximum daily dose is 37.5 mg.

6 to 12 years:

12.5 mg orally every 4 hours. Maximum daily dose is 75 mg.

> 12 years:

25 mg orally every 4 hours.

-or-

75 mg orally extended release every 12 hours.

Not to exceed 150 mg/day.

Renal Dose Adjustments

Because Rinostat Plus is eliminated primarily by the kidneys, one-half of the normally recommended dosage should be given. Patients with renal dysfunction should be monitored for signs and symptoms of toxicity when using Rinostat Plus.

Other Comments

In November 2000, the Food and Drug Administration (FDA), in response to reports of increased risk of hemorrhagic stroke, requested that all drug companies discontinue marketing products containing Rinostat Plus.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

More about Rinostat Plus

Related treatment guides

Rinostat Plus interactions

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What other drugs will affect Rinostat Plus?

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The benzodiazepines, including Ativan (lorazepam), produce increased CNS-depressant effects when administered with other CNS depressants such as alcohol, barbiturates, antipsychotics, sedative/hypnotics, anxiolytics, antidepressants, narcotic analgesics, sedative antihistamines, anticonvulsants, and anesthetics.

Concomitant use of clozapine and lorazepam may produce marked sedation, excessive salivation, hypotension, ataxia, delirium, and respiratory arrest.

Concurrent administration of lorazepam with valproate results in increased plasma concentrations and reduced clearance of lorazepam. Lorazepam dosage should be reduced to approximately 50% when coadministered with valproate.

Concurrent administration of lorazepam with probenecid may result in a more rapid onset or prolonged effect of lorazepam due to increased half-life and decreased total clearance. Lorazepam dosage needs to be reduced by approximately 50% when coadministered with probenecid.

The effects of probenecid and valproate on lorazepam may be due to inhibition of glucuronidation.

Administration of theophylline or aminophylline may reduce the sedative effects of benzodiazepines, including lorazepam.

Rinostat Plus side effects

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What are the possible side effects of Rinostat Plus?

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Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Constipation.

Skin rash.

Codeine can cause drowsiness, although at the dose contained in this medicine this is very unlikely. However, if you do find this medicine makes you feel sleepy or dizzy you should not drive or operate machinery and avoid alcoholic drink.

The side effects listed above may not include all of the side effects reported by the medicines’s manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

Rinostat Plus contraindications

See also:
What is the most important information I should know about Rinostat Plus?

Do not use lorazepam if you have narrow-angle glaucoma, or if you are allergic to lorazepam or to other benzodiazepines, such as alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), or oxazepam (Serax).

Before taking lorazepam, tell your doctor if you are allergic to any drugs, or if you have:

glaucoma;

asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems;

kidney or liver disease;

a history of depression or suicidal thoughts or behavior; or a history of drug or alcohol addiction.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.



Active ingredient matches for Rinostat Plus:

Phenylpropanolamine

Caffeine/Chlorpheniramine/Paracetamol/Phenylephrine


Unit description / dosage (Manufacturer)Price, USD
Rinostat Plus Acetaminophen 500mg, Phenylpropanolamine 25mg, Chlorpheniramine Maleate 4mg TAB / 6$ 0.17

List of Rinostat Plus substitutes (brand and generic names):

Rinostat Plus LIQD Acetaminophen 125mg, Phenylpropanolamine HCl12.5mg, ChlorpheniramineMaleate 1mg/5mL LIQD / 60ml$ 0.37
S-Cold Plus Citrizine HCl 5mg, Phenylpropanolamine HCl 25mg, Paracetamol 500mg, Chlorpheniramine Maleate 2mg TAB / 200$ 5.78
S-Cold Plus JR Phenylpropanolamine HCl6.25mg, Paracetamol 250mg, Chlorpheniramine Maleate 1mg DT-TAB / 200$ 3.37
Sinact 3 60 ml Syrup (Pharmatech Healthcare)$ 0.03
Capsule; Oral; Phenylpropanolamine Hydrochloride (Amino)
Sneezy- G Paracetamol 500mg, Phenylpropanolamine HCI 10mg, Chlorpheniramine Maleate 2mg, Caffine 30mg TAB / 10$ 0.14
Stopross Tablet (Emami Frank Ross Ltd)$ 0.04
Take D 50 ml Syrup (Indian Drugs and Pharmaceuticals Ltd (Ind Biosciences))$ 0.03
Take D 100 ml Syrup (Indian Drugs and Pharmaceuticals Ltd (Ind Biosciences))$ 0.02
Terrol Tablet (Jantec Pharma)$ 0.03
Toff Plus SYR Phenylpropanolamine HCI12.5mg, ChlorpheniramineMaleate 2mg SYR / 60ml$ 0.14
Triaminic E 60 ml Syrup (Wander Ltd)$ 0.02
Tricold SR 50+8 Capsule (Bhavishya Pharmaceuticals Pvt Ltd)$ 0.02
Trinol 60 ml Syrup (Arbro Pharmaceuticals Limited)$ 0.02
Tritus 15+25+4 Tablet (Burgeon Pharmaceuticals Pvt. Ltd.)$ 0.01
Tritus 50 ml Syrup (Burgeon Pharmaceuticals Pvt. Ltd.)$ 0.03
TRITUS 25MG/4MG/15MG SUSPENSION 1 bottle / 50 ML suspension each (Burgeon Pharmaceuticals Pvt. Ltd.)$ 0.48
TRITUS DROPS 1 packet / 15 ML drop each (Burgeon Pharmaceuticals Pvt. Ltd.)$ 0.26
TRITUS TABLET 1 strip / 10 tablets each (Burgeon Pharmaceuticals Pvt. Ltd.)$ 0.13
Tritus 25 mg/4 mg/15 mg Suspension (Burgeon Pharmaceuticals Pvt. Ltd.)$ 0.48
Tritus Drop (Burgeon Pharmaceuticals Pvt. Ltd.)$ 0.26
Tritus Tablet (Burgeon Pharmaceuticals Pvt. Ltd.)$ 0.01
Varcold SUSP Paracetamol 125mg, Phenylpropanolamine HCl12.5mg, ChlorpheniramineMaleate 1mg, Na citrate60mg/5mL SUSP / 30ml$ 0.29
Ventosol AP 100 ml Syrup (Intra Labs India Pvt Ltd)$ 0.02
Vicosyl P 60 ml Syrup (Vostok & Wilcure Remedies)$ 0.02
Wifi 25+5 Tablet (Grandcure Healthcare (P) Ltd)$ 0.06

References

  1. DailyMed. "CHLORPHENIRAMINE POLISTIREX; HYDROCODONE POLISTIREX: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  2. DailyMed. "CAFFEINE; ERGOTAMINE TARTRATE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
  3. PubChem. "phenylephrine". https://pubchem.ncbi.nlm.nih.gov/com... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Rinostat Plus are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Rinostat Plus. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

User reports

Consumer reported useful

No survey data has been collected yet


Consumer reported price estimates

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Consumer reported time for results

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3 consumers reported age

Users%
6-151
33.3%
30-451
33.3%
16-291
33.3%


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Information checked by Dr. Sachin Kumar, MD Pharmacology

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